The invention provides a control system and method of an artificial intelligence drive robot. The system comprises a receiving module, an artificial intelligence module, a central processing unit, a cloud processing module and an executing module. The method comprises the steps that scene information of the surrounding and voice and/or visual information of a user are acquired; a comprehensive decision is made after recognition and understanding according to voice and/or visual information; the intention of the user is confirmed, and the robot gives a response; and a treatment result is outputin multiple modes including one or more of moving of the intelligent robot, action of a mechanical arm and/or a head, expression video image display on a screen, and audio playing. According to the method, artificial intelligence analysis and decision can be carried out locally or through cloud uploading according to acquired voice and/or visual information, the robot is automatically controlledto be in interactive feedback with the user in multiple manners, much hardware can be arranged outside, a designer quickly expands a machine body, and an artificial intelligence result can be intuitively and effectively achieved on the robot.