Double-resistance anti-allergy composition, double-resistance anti-allergy skin care product and preparation method of double-resistance anti-allergy composition

By combining gentian extract and multiple plant soothing and repairing agents, a dual-anti-allergic skin care product is prepared, which solves the problems of skin sensitivity and redness, achieves rapid anti-itching, calming and analgesic effects, and significantly improves skin condition.

CN120713804APending Publication Date: 2025-09-30ZHUHAI CENTURY KANGMEI BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202511164966.3
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-08-20
Publication Date
2025-09-30

AI Technical Summary

Technical Problem

The ozone layer depletion caused by modern industry and excessive ultraviolet radiation cause skin sensitivity, redness and damage, which are difficult to be effectively alleviated by existing skin care products.

Method used

A combination of gentian extract and multiple plant soothing and repairing agents, including field mint leaf extract, golden chamomile extract, purslane extract, sophora flavescens root extract, aloe vera extract and geranium flower/leaf/stem extract, is used in combination with xanthan gum, butylene glycol, parahydroxyacetophenone and other ingredients to prepare a dual anti-allergic composition and skin care product that relieves skin problems through synergistic effects.

Benefits of technology

It can quickly relieve itching, calm and relieve pain, significantly reduce redness and anti-allergic effects, effectively repair damaged skin, and significantly improve skin sensitivity, redness and burning sensation.

✦ Generated by Eureka AI based on patent content.
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Abstract

The invention relates to the technical field of skin care products, in particular to a double-resistance anti-allergy composition in a skin care product and a preparation method of the skin care product. According to the double-resistance anti-allergy composition provided by the invention, the radix gentianae extract has the effects of resisting allergy, repairing, inhibiting skin redness and fever and effectively relieving skin pricking and burning, and the multi-plant soothing repairing agent can repair damaged skin, prevent and inhibit generation of inflammatory factors, quickly relieve itching, remove redness, resist allergy and relieve skin. The traditional Chinese medicine composition can effectively relieve skin pricking and burning feelings and relieve itching and has the effects of immediate analgesia and sedation, and the multiple plant relieving and repairing agents and the gentian plant extract can play a synergistic role to relieve skin sensitivity, redness, pain and burning feelings, relieve itching and the like. The double-resistance anti-allergy composition provided by the invention has obvious red fading and itching relieving effects in a skin care product with an optimal ratio. The preparation method of the anti-allergy, redness-removing and itching-relieving skin care product, provided by the invention, is simple, stable in process and easy to popularize.
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Description

Technical Field

[0001] The present invention relates to the technical field of skin care products, and in particular to a dual-anti-allergic anti-allergic composition, a dual-anti-allergic anti-allergic skin care product and a preparation method thereof. Background Art

[0002] As people's living standards continue to improve, beauty and skincare products are gradually becoming necessities rather than luxuries. Simultaneously, with social development and environmental changes, people are paying more and more attention to skin care, and their expectations for product efficacy are becoming increasingly refined. Due to the development of modern industry, air pollution has intensified in recent years, and ozone layer depletion has become increasingly serious. Excessive ultraviolet radiation can cause skin sensitivity, redness, and damage. Summary of the Invention

[0003] In order to overcome the shortcomings of the existing technology, one of the purposes of the present invention is to provide a dual anti-allergic and anti-itching composition. The anti-allergic, redness-reducing and itching-relieving composition is a combination of gentian extract and multiple plant soothing and repairing agents, which can play a synergistic role in alleviating skin sensitivity, redness, damage and other problems.

[0004] The technical solution solved by the present invention is a dual anti-allergic composition, which includes the following components in parts by mass: 0.2-30 parts of gentian extract, 0.1-25 parts of multiple plant soothing and repairing agents, 0.01-0.2 parts of xanthan gum, 0.5-30 parts of butylene glycol, 0.5-2 parts of preservatives, and 30-70 parts of water.

[0005] Preferably, the multiple plant soothing and repairing agent includes 0.01 to 1 parts of field mint leaf extract, 0.1 to 5 parts of golden chamomile extract, 0.01 to 8 parts of purslane extract, 0.001 to 2 parts of sophora flavescens root extract, 0.01 to 3 parts of aloe vera extract, 0.01 to 10 parts of geranium flower / leaf / stem extract, 5 to 25 parts of butylene glycol, 2 to 20 parts of glycerin, 0.2 to 1 part of 1,2-hexanediol, 0.2 to 1 part of parahydroxyacetophenone, and 5 to 30 parts of water.

[0006] Preferably, the gentian extract comprises 0.01 to 10 parts of gentian root extract, 10 to 50 parts of butylene glycol, and 20 to 50 parts of water.

[0007] A dual-anti-allergic skin care product comprising any one of the above dual-anti-allergic compositions.

[0008] A dual-anti-allergic skin care product further comprises the following components, calculated by weight: 0.01 to 1 parts of a thickener, 0.5 to 2 parts of an antioxidant, and 0.5 to 30 parts of a moisturizer.

[0009] Preferably, the thickener is selected from one or more of carbomer, crisp chondrus crispus, xanthan gum, acrylic acid (esters) / C10-30 alkyl acrylate crosspolymer, hydroxyethyl cellulose, lithium magnesium silicate, ammonium acryloyldimethyltaurate / VP copolymer;

[0010] The preservative or antioxidant is selected from one or two of phenoxyethanol, bis(hydroxymethyl)imidazolidinyl urea, iodopropynyl butylcarbamate, DMDM ​​hydantoin, chlorphenesin, methylparaben, propylparaben, sodium benzoate, potassium sorbate, p-hydroxyacetophenone, and caprylhydroxamic acid;

[0011] The moisturizing agent is selected from one or more of 1,2-hexanediol, glycerol, butanediol and 1,2-pentanediol.

[0012] Preferably, the pH value of the dual-anti-allergic skin care product is 5.0-8.0.

[0013] A method for preparing a dual-anti-allergy skin care product, comprising the following steps:

[0014] a) thoroughly stirring water, a thickener, a humectant, and an antioxidant at 75-85° C. to obtain a first mixture;

[0015] b) cooling the first mixture to 40-45° C., adding gentian root extract and multiple plant soothing and repairing agents in sequence, and stirring evenly to obtain a dual anti-allergic skin care product.

[0016] Preferably, the stirring speed of step a) is 30-40 rpm, and the stirring speed of step b) is 20-30 rpm.

[0017] Preferably, after the stirring in step b), and before obtaining the dual-anti-allergic skin care product, the process further comprises: cooling to 35-40° C. and stirring evenly at 15-20 rpm.

[0018] The beneficial effects of the present invention are:

[0019] The present invention provides a dual anti-allergic and anti-allergic composition, in which gentian extract has the effects of anti-allergic, repairing, inhibiting skin redness and fever, and effectively relieving skin tingling and burning sensations. Multiple plant soothing and repairing agents can repair damaged skin, prevent and inhibit the production of inflammatory factors, quickly relieve itching and redness, anti-allergic and soothing, effectively relieve skin tingling, burning and itching, and have instant analgesic and sedative effects. Multiple plant soothing and repairing agents and gentian plant extracts can play a synergistic role in the optimal ratio to relieve skin sensitivity, redness, pain, burning, itching, damage and other problems.

[0020] The present invention provides a dual-anti-allergic and anti-itching skin care product, comprising an anti-allergic, redness-reducing and itching-relieving composition, which has obvious redness-reducing and itching-relieving effects.

[0021] The present invention provides a method for preparing a dual-anti-allergic and anti-itching skin care product. The preparation method is simple and the process is stable. The prepared skin care product has good anti-allergic, redness-reducing and itching effects and is easy to promote. DETAILED DESCRIPTION

[0022] The present invention will be further described below in conjunction with specific implementation methods. It should be noted that, under the premise of no conflict, the various embodiments or technical features described below can be arbitrarily combined to form new embodiments.

[0023] The following are specific embodiments of the present invention. Unless otherwise specified, the raw materials, equipment, etc. used in the following embodiments can be obtained by purchase.

[0024] In a specific embodiment, gentian extract was purchased from Shanghai Jiayu Biotechnology Co., Ltd., and the mass ratio of gentian root extract, butylene glycol, and water was 5:50:54; the multiple plant soothing and repairing agent was purchased from Guangzhou Jizhou Trading Co., Ltd., and the mass ratio of field mint leaf extract, golden chamomile extract, purslane extract, sophora flavescens root extract, aloe vera extract, geranium flower / leaf / stem extract, butylene glycol, glycerin, 1,2-hexanediol, p-hydroxyacetophenone, and water was 3:10:14.5:1:2.5:7:20:12:0.5:0.5:29; xanthan gum was purchased from Guangzhou Hengyuan Biotechnology Co., Ltd.; butylene glycol was purchased from Oujiya Chemical Company; p-hydroxyacetophenone was purchased from Guangzhou Unico Technology Development Co., Ltd.; and 1,2-hexanediol was purchased from Guangzhou Unico Technology Development Co., Ltd.

[0025] Example 1

[0026] In this embodiment, an anti-allergic, redness-reducing, and itching-relieving skin care product is prepared. The raw materials include, by mass, 5 parts of gentian extract, 5 parts of multiple plant soothing and repairing agents, 0.01 parts of xanthan gum, 10 parts of butylene glycol, 0.5 parts of 1,2-hexanediol, 0.5 parts of p-hydroxyacetophenone, and 30 parts of water.

[0027] The preparation method is as follows:

[0028] a) stirring xanthan gum, butylene glycol, p-hydroxyacetophenone, and water at 85° C. and 30 rpm to obtain a first mixture;

[0029] b) Cooling the first mixture to 50° C., adding gentian extract, multiple plant soothing and repairing agents, and 1,2-hexanediol in sequence, stirring evenly at 20 rpm, then cooling to 35° C., stirring evenly at 20 rpm, and filtering to obtain a dual-anti-allergic skin care product.

[0030] Example 2

[0031] In this embodiment, an anti-allergic, redness-reducing, and itching-relieving skin care product is prepared. The raw materials include, by mass, 4 parts of gentian extract, 6 parts of multiple plant soothing and repairing agents, 0.02 parts of xanthan gum, 15 parts of butylene glycol, 0.5 parts of 1,2-hexanediol, 0.4 parts of p-hydroxyacetophenone, and 25 parts of water.

[0032] The preparation method is as follows:

[0033] a) stirring xanthan gum, butylene glycol, p-hydroxyacetophenone, and water at 75° C. and 32 rpm to obtain a first mixture;

[0034] b) Cooling the first mixture to 45° C., adding gentian extract, multiple plant soothing and repairing agents, and 1,2-hexanediol in sequence, stirring evenly at 25 rpm, then cooling to 38° C., stirring evenly at 25 rpm, and filtering to obtain a dual-anti-allergic skin care product.

[0035] Example 3

[0036] In this embodiment, an anti-allergic, redness-reducing, and itching-relieving skin care product is prepared. The raw materials include, by mass, 6 parts of gentian extract, 4 parts of multiple plant soothing and repairing agents, 0.01 parts of xanthan gum, 20 parts of butylene glycol, 0.6 parts of 1,2-hexanediol, 0.4 parts of p-hydroxyacetophenone, and 20 parts of water.

[0037] The preparation method is as follows:

[0038] a) stirring xanthan gum, butylene glycol, p-hydroxyacetophenone, and water at 80° C. and 35 rpm to obtain a first mixture;

[0039] b) Cooling the first mixture to 40° C., adding gentian extract, multiple plant soothing and repairing agents, and 1,2-hexanediol in sequence, stirring evenly at 15 rpm, then cooling to 38° C., stirring evenly at 15 rpm, and filtering to obtain a dual-anti-allergic skin care product.

[0040] Comparative Example 1

[0041] The difference between Comparative Example 1 and Example 3 is that the proportions of gentian extract and multiple plant soothing and repairing agents in the raw materials are different, but the mass content of the dual anti-allergic composition in the anti-allergic, redness-reducing and itching-relieving skin care products is the same as that in Example 3.

[0042] 3 parts of gentian extract, 5 parts of multi-plant soothing and repairing agent, 0.01 parts of xanthan gum, 10 parts of butylene glycol, 0.5 parts of 1,2-hexanediol, 0.5 parts of p-hydroxyacetophenone, 30 parts of water;

[0043] a) stirring xanthan gum, butylene glycol, p-hydroxyacetophenone, and water at 85° C. and 30 rpm to obtain a first mixture;

[0044] b) cooling the first mixture to 50° C., adding gentian extract, multiple plant soothing and repairing agents, and 1,2-hexanediol in sequence and stirring uniformly at 20 rpm, then cooling the mixture to 35° C., stirring uniformly at 20 rpm, and filtering to obtain an anti-allergic, redness-reducing, and itching-relieving skin care product.

[0045] Comparative Example 2

[0046] The difference between Comparative Example 2 and Example 3 is that the proportions of gentian extract and multiple plant soothing and repairing agents in the raw materials are different, but the mass content of the dual anti-allergic composition in the anti-allergic, redness-reducing and itching-relieving skin care products is the same as that in Example 3.

[0047] In this embodiment, an anti-allergic, redness-reducing, and itching-relieving skin care product is prepared. The raw materials include, by mass, 3 parts of gentian extract, 3 parts of multiple plant soothing and repairing agents, 0.02 parts of xanthan gum, 15 parts of butylene glycol, 0.5 parts of 1,2-hexanediol, 0.4 parts of p-hydroxyacetophenone, and 25 parts of water.

[0048] The preparation method is as follows:

[0049] a) stirring xanthan gum, butylene glycol, p-hydroxyacetophenone, and water at 75° C. and 32 rpm to obtain a first mixture;

[0050] b) cooling the first mixture to 45° C., adding gentian extract, multiple plant soothing and repairing agents, and 1,2-hexanediol in sequence, stirring evenly at 25 rpm, then cooling to 38° C., stirring evenly at 25 rpm, and filtering to obtain an anti-allergic, redness-reducing, and itching-relieving skin care product.

[0051] Comparative Example 3

[0052] The difference between Comparative Example 3 and Example 3 is that the raw materials do not contain gentian extract, but the mass content of the dual anti-allergic, redness-reducing and itching-relieving composition in the skin care product is the same as that in Example 3.

[0053] This comparative example is used to prepare anti-allergic, redness-reducing and itching-relieving skin care products. The raw materials include 4 parts of multiple plant soothing and repairing agents, 0.01 parts of xanthan gum, 20 parts of butylene glycol, 0.6 parts of 1,2-hexanediol, 0.4 parts of p-hydroxyacetophenone and 20 parts of water, calculated by mass.

[0054] The preparation method is as follows:

[0055] a) stirring xanthan gum, butylene glycol, p-hydroxyacetophenone, and water at 80° C. and 35 rpm to obtain a first mixture;

[0056] b) cooling the first mixture to 40° C., adding the multiple plant soothing and repairing agents and 1,2-hexanediol in sequence and stirring evenly at 15 rpm, then cooling the mixture to 38° C., stirring evenly at 15 rpm, and filtering to obtain an anti-allergic, redness-reducing, and itching-relieving skin care product.

[0057] Performance Testing

[0058] The dual-anti-allergic skin care products prepared in Examples 1 to 3 of the present invention were sampled and tested, and all of them were slightly yellow mucus, meeting the specified fragrance. After dilution 10 times, the pH value was 5.0-8.0, the total bacterial count (CFU / g, ml): ≤100, and the total mold and yeast count (CFU / g, ml): ≤100.

[0059] The anti-allergic, redness-reducing and itching-relieving skin care products prepared in Examples 1 to 3 of the present invention and Comparative Examples 1 to 3 were used to conduct effect tests.

[0060] 60 subjects were randomly selected and all subjects were randomly divided into 6 groups, with 10 subjects in each group. Each group was evenly smeared with the same diluted histamine on the arm. After 10 minutes, the subjects could consciously produce burning, pain, redness and itching locally. Then, the redness-reducing skin care products prepared in Examples 1 to 3 or Comparative Examples 1 to 3 were evenly applied at a dosage of 0.5 mg / cm2 and the time was measured. The different skin conditions were observed after 5, 10 and 20 minutes, respectively. The following standards were used to statistically evaluate the effects of use: significant effect: the erythema basically disappeared, the burning and pain were completely eliminated; effective: the erythema was reduced by 50% to 80%, the border was significantly lighter, and the burning and pain were significantly reduced; ineffective: the erythema did not change significantly or the reduction was less than 50%.

[0061] Please refer to Table 1 for the test results, which are the test results of the anti-allergic, redness-reducing and itching-relieving skin care products of Examples 1 to 3 of the present invention and Comparative Examples 1 to 3. The experimental results show that after the subjects used the anti-allergic, redness-reducing and itching-relieving skin care products of Examples 1 to 3 of the present invention and Comparative Examples 1 to 3 for 5, 10 and 20 minutes, the redness, itching, burning and pain were improved to a certain extent. The total effective rate of the subjects using the redness-reducing skin care products of Examples 1 to 3 of the present invention reached 90%, among which the number of subjects who used the redness-reducing skin care products of Example 3 was the largest. Compared with Example 3, the subjects using Comparative Examples 1 and 2 had significantly lower erythema, burning and pain, and were poor in the itching and calming effects. This shows that the present invention adopts the combination of gentian extract and multiple plant soothing and repairing agents in different proportions, which can achieve a synergistic effect in the redness-reducing, itching and calming effects at the optimal proportion.

[0062] Table 1 Test results of the dual anti-allergic skin care products of Examples 1 to 3 of the present invention and Comparative Examples 1 to 3

[0063] Group Number of people with significant effects Effective number of people Invalid number of people Total efficiency Example 1 6 3 1 90% Example 2 7 2 1 90% Example 3 9 1 0 100% Comparative Example 1 5 3 2 80% Comparative Example 2 4 3 3 70% Comparative Example 3 3 2 5 50%

[0064] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principles of the present invention. These improvements and modifications should also be regarded as within the scope of protection of the present invention.

Claims

1. A dual anti-allergic composition, characterized in that: The composition includes the following components in parts by mass: 0.2 to 30 parts of gentian extract, 0.1 to 25 parts of multiple plant soothing and repairing agents, 0.01 to 0.2 parts of xanthan gum, 0.5 to 30 parts of butylene glycol, 0.5 to 2 parts of preservatives, and 30 to 70 parts of water.

2. A dual anti-allergic composition according to claim 1, characterized in that: The multiple plant soothing and repairing agent includes 0.01 to 1 parts of field mint leaf extract, 0.1 to 5 parts of golden chamomile extract, 0.01 to 8 parts of purslane extract, 0.001 to 2 parts of sophora flavescens root extract, 0.01 to 3 parts of aloe vera extract, 0.01 to 10 parts of geranium flower / leaf / stem extract, 5 to 25 parts of butylene glycol, 2 to 20 parts of glycerin, 0.2 to 1 part of 1,2-hexanediol, 0.2 to 1 part of parahydroxyacetophenone, and 5 to 30 parts of water.

3. A dual anti-allergic composition according to claim 1, characterized in that: The gentian extract comprises 0.01 to 10 parts of gentian root extract, 10 to 50 parts of butylene glycol and 20 to 50 parts of water.

4. A dual-anti-allergic skin care product, characterized in that: The invention comprises the dual-antiallergic anti-allergic composition according to any one of claims 1 to 3.

5. The dual-anti-allergy skin care product according to claim 4, characterized in that: The invention also includes the following components by weight: 0.01 to 1 parts of thickener, 0.5 to 2 parts of antioxidant, and 0.5 to 30 parts of moisturizer.

6. The dual anti-allergic skin care product according to claim 5, characterized in that: The thickener is selected from one or more of carbomer, crisp wave carrageenan, xanthan gum, acrylic acid (esters) / C10-30 alkyl acrylate crosspolymer, hydroxyethyl cellulose, lithium magnesium silicate, ammonium acryloyldimethyltaurate / VP copolymer; The preservative or antioxidant is selected from one or two of phenoxyethanol, bis(hydroxymethyl)imidazolidinyl urea, iodopropynyl butylcarbamate, DMDM ​​hydantoin, chlorphenesin, methylparaben, propylparaben, sodium benzoate, potassium sorbate, p-hydroxyacetophenone, and caprylhydroxamic acid; The moisturizing agent is selected from one or more of 1,2-hexanediol, glycerol, butanediol and 1,2-pentanediol.

7. The dual anti-allergic skin care product according to claim 5, characterized in that: The pH value of the dual-anti-allergic skin care product is 5.0-8.

0.

8. The method for preparing a dual-anti-allergic skin care product according to any one of claims 4 to 7, characterized in that: The following steps are involved: a) thoroughly stirring water, a thickener, a humectant, and an antioxidant at 75-85° C. to obtain a first mixture; b) cooling the first mixture to 40-45° C., adding gentian extract and multiple plant soothing and repairing agents in sequence and stirring evenly to obtain a dual anti-allergic skin care product.

9. The method for preparing a dual-anti-allergic skin care product according to claim 8, characterized in that: The stirring speed of step a) is 30-40 rpm, and the stirring speed of step b) is 20-30 rpm.

10. The method for preparing a dual-anti-allergic skin care product according to claim 8, characterized in that: After the stirring in step b), and before obtaining the dual-anti-allergic skin care product, the method further comprises: cooling the mixture to 35-40° C. and stirring the mixture evenly at 15-20 rpm.