Novel application and preparation method of biological retina

Abstract

The invention provides a biological retina, which is applied to tissue repair in the field of ophthalmological department. The tissue repair includes glaucoma trabeculectomy, a neovascular glaucoma surgery, uveitic glaucoma, a pterygium surgery, a strabismus surgery, a nasolacrimal duct operation, an orbital surgery, an ocular plastic surgery, a conjunctival scar tissue reconstruction surgery, a burn repair surgery and a corneal ulcer surgery; and the preparation method comprises the following steps: preparing a high-purity type I collagen and glacial acetic acid water solution according to a preset proportion and emulsifying; and vacuumizing the emulsified slurry and freeze-drying the slurry so as to obtain a collagen film having a three-dimensional porous structure. The biological retina disclosed by the invention has beneficial effects that the prepared biological retina, which takes the collagen, as a major ingredient, is good in biocompatibility and biodegradability and is capable of controlling an inflammatory reaction; the high-purity collagen is free from antigenicity and repellency; by virtue of the three-dimensional porous structure, the random and discrete hyperplasia of fibroblasts is guided; and the biological retina can inhibit conjunctival scars and conjunctival contraction, and can keep normal intraocular pressure.

Description

technical field [0001] The invention relates to the field of medical materials, in particular to a new application of a biological retina and a preparation method thereof. Background technique [0002] In the treatment of preventing scarring of damaged tissues after ophthalmic surgery, the commonly used anti-metabolite drug treatment methods have shortcomings, and careless application may even bring some negative effects. Finding more effective and safer biomedical materials is currently the One of the directions of ophthalmology research, and biological retina is an ideal eye tissue repair material. [0003] The main raw material of biological retina is high-purity type I collagen. Collagen is mainly distributed in the connective tissue of mammals. It is very important for the formation of animal and human skin, blood vessels, bones, tendons, teeth and cartilage. These connective The main material basis of the organization, the molecular weight is 300KD. The most common s...

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Problems solved by technology

[0011] The present invention also proposes a method for preparing biological retina, which solves the problem that there is no better method for preparing biological retina in the prior art

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