62results about How to "Conformationally stable" patented technology

The invention discloses a moon cake. The moon cake comprises a moon cake cladding and a moon cake filling, wherein the moon cake cladding comprises the following raw materials: 40 to 70 percent of wheat flour, 20 to 45 percent of sugar alcohol, 2 to 8 percent of L-arabinose, 5 to 20 percent of animal and vegetable oil or hydrogenated animal and vegetable oil and 0.2 to 2 percent of alkaline water. The technical problems of soft cladding and poor plasticity caused by the low viscosity of a sugar-free moon cake which takes maltitol solution as a cladding in the prior art are solved. Therefore, the moon cake has the characteristics of easily-shaped cladding, high plasticity and stable texture in baking process.

The invention provides a preparation method of alvimopan and an intermediate for synthesizing the alvimopan. The preparation method comprises the following steps of: designing a process route through a two-chain method, respectively synthesizing initial raw materials, then condensing and hydrolyzing to obtain the alvimopan. The method can be used for directionally synthesizing a single optical isomer through N-alkylation reaction under an alkaline condition, the configuration change of the chiral centers of the raw materials and the product can not be generated both in reaction conditions anda post-processing method, and the obtained product can be hydrolyzed into the alvimopan under the mild alkaline condition.

The invention provides an integrated platform supporting hinge, which comprises an integrated connecting rod, a magnetometer, an attitude measuring instrument, a Y-shaped supporting flexible hinge, asupporting platform and an I-shaped supporting flexible hinge. The magnetometer and the attitude measuring instrument are arranged at two ends of the integrated connecting rod respectively; and the integrated connecting rod is connected to the supporting platform in a supporting mode through the Y-shaped supporting flexible hinge and the I-shaped supporting flexible hinge. Through thermodynamic decoupling of the Y-shaped supporting flexible hinge and the I-shaped supporting flexible hinge in two dimensions and high rigidity in the vertical direction, no-thermal stress support of the Y-shaped supporting flexible hinge and the I-shaped supporting flexible hinge and constancy of the positions of key components of the magnetometer are realized, thereby facilitating scientific tests and applications in satellite fields such as space magnetic field and gravitational field detection. The integrated platform supporting hinge has the advantages of no thermal stress support, constant key component pose, stable platform configuration, high support rigidity, reliable performance and simple structure and the like.

The invention relates to a preparation method of a pH sensitive element based on DNA molecule configuration change. The preparation method comprises the following steps: preparing a DNA self-assembling structure; and adsorbing a DNA molecule and a gold base to obtain the pH sensitive element. The DNA molecule is subjected to the action of H<+1> under an acidic condition and a chain segment has the configuration change to a certain extent; and meanwhile, some DNA chain segments which are sensitive to pH, such as i-motig chain segments, are folded under the action the H<+1>, so that the change of the pH can be directly reflected through the change of the configuration by the DNA molecule. According to the preparation method, the DNA molecule is modified on a gold surface, a material preparation process is developed and the maneuverability is strong; the sensitivity to the change of the pH is high and a rapid reaction can be realized; and a proton-driven environment-friendly and clean reversible biological change-over switch device is provided and has a wide application prospect in the field of biosensors and the field of clean energy sources.

The invention discloses an all-steel tubeless radial tire with a high load performance and a manufacturing method thereof. A rectangular bead ring is arranged in a compound bead ring; a section designangle is adopted by a profile curve at the bottom of a bead base; a tangent design angle is adopted by the profile curve of a tire bead heel; a sizing material is thickened on a contact position of the bead heel and the rim; binding rubber slices are arranged at two endpoints of a tire cord fabric and a reinforced cord fabric; the height of reverse binding sections of the binding rubber slices isarranged close to the height H1 of a horizontal shaft; an upper filling glue and a lower filling glue for isolation are successively arranged between the reverse binding sections of the binding rubber slices and the tire body from top to bottom; a U-shaped reinforced cord fabric layer is paved on the outer layer of the tire cord fabric; an inside liner and a sidewall compound piece are respectively arranged on the inner and outer sides of the reinforced cord fabric. The bead ring is stable in construction, is free from deformation under a stressed state and is high in strength use ratio; thebottom of the bead ring is in surface contact with the rim; the stress is uniform and the load resistance is promoted; the stress between the tire body and the tire cord fabric is buffered by the isolating rubber slices; the loading capacity is promoted by the reinforced cord fabric.

The invention discloses a nano-pore detection system based on a nano-tube and a preparation method and application thereof. The system comprises a nano-pore structure based on the nano-tube, a micro-channel structure, a cover plate for sealing the micro-channel structure, and a current detection system for detecting a to-be-detected object. The nano-pore structure based on the nano-tube comprises a substrate and the nano-tube. The nano-tube is dispersed or grows on the substrate, openings are formed in the left end and the right end of the nano-tube, and a nano-pore is formed in the side wall. The micro-channel structure is machined on the substrate and provided with three independent electrolyte solution cavities, the nano-tube penetrates through the three cavities, and the left opening, the nano-pore and the right opening of the nano-tube are communicated with the first cavity, the second cavity and the third cavity respectively. One end of the current detection system is arranged in the second cavity, and the other end of the current detection system is arranged in the first cavity or the third cavity. The resolution and sensitivity of a bio-sensor can be greatly improved, and the concept of single molecule DNA direct sequencing is expected to be achieved.

The invention discloses a preparation method of a Fenton-like catalytic material having double reactive active centers. The preparation method comprises: (1) placing a nitrogen-containing compound ina muffle furnace, calcining the nitrogen-containing compound and dissolving the product in deionized water to form a suspension solution, (2) dissolving aluminum nitrate nonahydrate, copper nitrate trihydrate and glucose in deionized water to obtain a solution C, (3) adding the suspension solution into the solution C drop by drop, carrying out a closed hydrothermal reaction process and carrying out washing, centrifugation and drying to obtain solids, and (4) calcining the solids in the muffle furnace to obtain the Fenton-like catalytic material. The catalytic material has a complete spheroidalflower-like mesoporous structure with a large specific surface area and can expose more catalytic active sites, so that H2O2 undergoes a reduction reaction at the electron-rich center as much as possible during the reaction to generate hydroxyl radicals. The novel catalytic material has good removal effects on various toxic and harmful organic pollutants under neutral conditions, and can achievehighly selective conversion of H2O2.

The present invention relates to one kind of medicine composition of cefuroxime ester microcapsule and its preparation process. The cefuroxime ester microcapsule consists of cefuroxime ester and filming material, selected from ethyl cellulose and acrylic resin type L or S, in the weight ratio of 1 to 0.5-5, as well as additive, selected from polyvidone, polyethylene glycol and hydroxypropyl ethyl cellulose, in the amount of 10-50 wt% of the filming material. The prepared granule and dry suspension have excellent effects of masking bitter taste, raising excorporeal leaching rate, etc.

The invention discloses an enhanced azo Salen Schiff base fluorescent probe and synthesis and application thereof, belonging to the technical field of fluorescent probes. The chemical formula of the fluorescent probe is C39H34N8O7, and the structural formula of the fluorescent probe is as shown in the specification. The fluorescent probe has good selectivity on Al <3+>, good linear relation, highsensitivity, strong fluorescence response, low detection limit and low cost, and can be widely applied to detection of Al<3+> ions in an environment. Compared with the prior art, the fluorescent probeof the invention has the advantages that more than one time of coordination sites can be provided; the fluorescent probe is more easily coordinated with Al<3+> to form a binuclear complex with a plurality of coordination sites; and molecular plane rigidity is enhanced after coordination, so the photoinduced electron transfer effect of Schiff base nitrogen atoms is inhibited, and a strong chelating fluorescence enhancement effect is generated. The synthesis method of the probe is simple, and has high yield, and reaction conditions are easy to control.

The invention discloses a mold-proof, antibacterial and anti-corrosion cable used for power transmission. The cable comprises three conductors (1). An inner isolating layer (2) wrapped by a mica sub-band is arranged outside each conductor (1). An insulating layer (3) is arranged outside each inner isolating layer (2). An outer isolating layer (4) wrapped by a mica sub-band and aramid fiber is arranged outside the insulating layers (3) of the three conductors (1). A polyethylene sheath (5) and a mold-proof polypeptide thin film layer (7) sequentially wrap the outer isolating layer (4). A fire-resistant filling material (6) is arranged between the insulating layers (3) of the three conductors and the outer isolating layer (4) wrapped by the mica sub-band and the aramid fiber. The developed cable has extremely strong antibacterial and anti-corrosion functions, the preparation mode is easy and convenient, and the effect can be achieved without special processes. The cable has the advantages of being low in input, high in yield and capable of saving resources.

The invention provides cyanodiphenylethylene compound with stable Z/E configuration in excited state and a preparation method and application thereof. The cyanodiphenylethylene compound with stable Z/E configuration in excited state acts as a novel light-emitting isomer; the structure can be controlled by introducing different push-pull electron groups so as to adjust light emission color and efficiency of the isomer; therefore, the cyanodiphenylethylene compound has a very promising application prospect in the fields, such as photoluminescence, piezochromism and fluorescent sensing.

The invention relates to a preparation method of polyimide nanofiber aerogel with a controllable microstructure. The preparation method is characterized by comprising the following steps: step 1, preparing polyimide into a nanofiber dispersion solution; step 2, carrying out freezing crystallization on the nanofiber dispersion solution to manufacture a micro-configuration so as to obtain a nanofiber dispersion solution crystalline phase; step 3, removing ice crystals of the crystalline phase of the nanofiber dispersion solution to obtain an uncrosslinked nanofiber skeleton; and step 4, heatingthe non-crosslinked nanofiber skeleton to stabilize the configuration, thereby obtaining the polyimide nanofiber aerogel. The freezing nucleation of the solvent is directionally controlled by controlling the freezing speed and the temperature gradient so that the framework construction of the polyimide nanofiber is controlled, and the macroscopic functional characteristics of the material are determined. Compared with a traditional method, the method is simple and convenient and convenient to control technological parameters, and the operation efficiency and the product success rate can be improved.

The invention discloses a deformable wheel-track composite walking mechanism. The deformable wheel-track composite walking mechanism comprises a deformable wheel-track main frame used for enabling the outer contour to be transformed between a flat and long octagon and a quasi-circular shape; a track, wherein the outer edge of the deformable wheel track main frame is coated with the track, and the shape of the track can be changed under the driving of the deformable wheel track main frame; a track driving device which is arranged at the middle position in the deformable wheel-track main frame and is used for driving the crawler belt to rotate; a wheel-track main frame driving device which is arranged in the middle of the outer surface of the deformable wheel-track main frame and used for driving the deformable wheel-track main frame to turn over. According to the deformable wheel-track main frame, based on the multi-connecting-rod movement principle, the driving triangular wheel sets are driven by the deformation driving devices to slide in the corresponding groove holes of the limiting plates, then the triangular wheel sliding wheels and the longitudinal adjusting wheels are driven, and the deformable wheel-track main frame is converted between the quasi-circular configuration and the flat and long configuration; the maneuvering performance and the passing performance of the platform walking mechanism are enhanced, and maintenance and repair are easy.

The invention discloses a method for improving the stability of monascus pigment in compound wine and a pigment protective agent. The method comprises the following steps of: 1) uniformly mixing ethylenediamine tetraacetic acid, a traditional Chinese medicinal material extract, a food ingredient containing free amino, alpha-cyclodextrin and/or gamma-cyclodextrin according to a formula ratio to prepare the pigment protective agent; 2) weighing solid red yeast rice, the monascus pigment or red yeast rice powder, adding the pigment protective agent, adding an acidity regulator, extracting, cooling to room temperature, and filtering to obtain monascus pigment leachate; and 3) adding the monascus pigment leachate into the compound wine until the color value of the compound wine is 0.2 to 3.0, and adding the acidity regulator until the pH of the compound wine is between 5.5 and 7.5 to obtain a finished product. According to the method, the monascus pigment and the compound wine are separately extracted, so that the monascus pigment is protected from the beginning of production; and the pigment protective agent comprises the food ingredient containing the free amino, and the free amino can be combined with groups which are easily degraded in the monascus pigment to further protect the monascus pigment.

The present invention relates to a slide bearing (27) for telescopic booms or arms (3, 72) which are extendable and retractable under load and which comprise a plurality of boom or arm sections (5, 7, 9, 73, 75, 77) being movable with respect to each other, wherein said slide bearing (27) comprises: a first section (30) in form of a housing, comprising a central recess (31), being adapted to receive a second (32) and a third (29) section, a second section (32) being received in said central recess (31) of said first housing section (30), and a third section (29), being smoothly in contact with said second section (32) and comprising a sliding surface (47), said third section (29) serving as slide plate of the slide bearing (27), wherein said second section (32) comprises a central inner recess (41) opening to the bottom of the central recess (31) of the first section (30) and extending into said second section (32) until a base section (42) thereof, and wherein said second section (32) comprises a load deflection curve starting from a rather flat part and turning into and ending in a very steep part. Furthermore, the present invention relates to a telescopic boom or arm comprising such bearings (27) and a shotcrete manipulator or robot comprising such boom with such bearing (27).

The invention discloses a composition containing pravastatin calcium as well as a preparation method and application thereof. The composition contains the following components in parts by weight: 1 part of pravastatin calcium, 110-300 parts of L-arginine, 30-90 parts of taurine, 20-80 parts of L-citrulline and 5-20 parts of vitamin E. When made into oral tablets or hard capsules, the composition meets the requirement of pharmaceutical stability, the therapeutic action of the composition on hyperlipidemia is improved, and the composition has remarkable economic and social benefits.

The invention discloses an intelligent color-changing liquid crystal fabric and a preparation method and application thereof, and belongs to the technical field of fine chemical engineering and material science. The intelligent color-changing liquid crystal fabric which takes a two-dimensional Mxene material as a photoelectric-thermal multi-stimulus layer and a cholesteric liquid crystal microcapsule coating as a thermochromic layer is prepared by adopting a static layer-by-layer self-assembly and screen printing coating method. The intelligent color-changing liquid crystal fabric prepared by the method can reversibly change color under the stimulation of an electric field, infrared light and temperature, is bright and changeable in color and sensitive in response, and has good solvent resistance and water resistance.

The invention discloses a sheet-shaped punched part. The sheet-shaped punched part comprises an upper punched body, a position clamping corner and a lower punched body. The position clamping corner is arranged at the position of connection between the upper punched body and the lower punched body. Circular corners are arranged on the two sides of the top of the upper punched body respectively, a plurality of fixing holes are formed in the four corners of the upper punched body, circular corners are arranged on the two sides of the bottom of the lower punched body, and a plurality of fixing holes are formed in the four corners of the lower punched body. The sheet-shaped punched part is simple in structure, practical in function and low in cost. Due to the fact that the position clamping corner is arranged, the sheet-shaped punched part can be clamped on a rear cover of a liquid crystal display screen, and the liquid crystal display screen can be firmly fixed. Due to the fact that the corners of the sheet-shaped punched part are designed to be circular corners, the sheet-shaped punched part is attractive in appearance and stable in structure, and easy to implement, meets an existing trend of the market, and has the good application prospect.

The invention discloses a lipid-based drug of a serum degradable carrier and an application method of the lipid-based drug, and belongs to the technical field of pharmacy. The lipid-based drug of the serum degradable carrier is characterized by comprising a liposome and serum, the liposome is formed by coating the drug with lecithin zirconium nanometer particles, dosage ratio of the liposome and the serum is 184-191 microgram: 1.5mL, and the application method is that the carrier or the lipid-based drug is externally injected into the serum. Pressure in terms of acidity, salinity and oxidation metabolite is not caused to blood cells by a degradation product, efficiency of directional delivery and target recognition of the drug to recipient cells can be improved, the lipid-based drug has the advantages of high mechanical strength and stability of drug coating conformation, and can be widely applied for developing slow-release drugs with a low blood cell immune response and no residual and for preparing a novel formulation with controlled release and efficient delivery of ribosome profilin.

The invention provides crystalline graphene, a preparation method thereof and modified asphalt, and the preparation method comprises the following steps: (1) placing high-activity Ca (OH) 2 powder in a reaction furnace, heating to a preset temperature in an inert protective atmosphere, and keeping the temperature; wherein the content of Ca (OH) 2 in the high-activity Ca (OH) 2 powder is not less than 90% by mass, the content of Mg (OH) 2 is 0.1-5% by mass, and the balance is impurities; (2) introducing a carbon source into the reaction furnace, and carrying out chemical vapor deposition reaction to obtain a solid-phase product; (3) carrying out acid pickling on the solid-phase product to obtain a crystalline graphene blank; and (4) placing the crystalline graphene blank in a furnace containing hydrogen or carbon dioxide atmosphere, and performing high-temperature etching to obtain the crystalline graphene. The crystalline graphene can be highly matched with an asphalt mixture, and the high and low temperature performance of asphalt is improved.

The present invention belongs to the field of aircraft design, and in particular, to an aircraft product pattern changing category control method. According to the aircraft product changing category control method, when researching and developing an aircraft collaborative design platform, a fast changing sheet is made into a form, and when the aircraft collaborative design platform edits and sends the fast changing sheet, a changing category of a product pattern is associated with a stage tag, and when an aircraft is shaped, that is, when the stage tag of the product pattern is D or P, the category of the fast changing sheet is limited to category 1 or category 2, so as to effectively avoid a shaped product from having a fast changing sheet of category 3 or category 4. According to the method provided by the present invention, a mess of the changing category of aircraft product patterns is eliminated, delay execution of important design changes is avoided, orderly scientific research and production are ensured, and the method has relatively large practical application values.