86 results about "Photoinduced electron transfer" patented technology

The present invention provides fluorogenic compounds for the detection of target metal ions wherein the compounds exhibit a Stokes shift greater than 50 nm and the detectable signal is modulated by photoinduced electron transfer (PET). The present compounds consist of three functional elements, the ion sensing moiety (chelating moiety), the reporter moiety (fluorophore or fluorescent protein) and spacer or linker between the sensing and reporter moieties of the present compound that allows for PET upon binding of a metal ion and excitation by an appropriate wavelength.

The invention discloses a preparation method for a titanium dioxide nano particle fluorescence probe for detection DDT. In the method, TiO2 is used as a core, and modified with 4-chloro-7-nitrobenzofuran fluorescence probe and aminopropyl functional groups on the surface, and at last quasi target molecules are printed on the surface, so that a silicon dioxide printed shell layer is formed. The preparation process of the fluorescence probe comprises three steps of 1, preparation of a fluorescence precursor; 2, silanization of the quasi target molecules, and 3, preparation and elution of the titanium dioxide nanoparticles printed with the quasi target molecules. The target molecule DDT enters a recognition site, a helium atom of the DDT and a hydrogen atom of aminopropyl form a hydrogen bond, so that the aminopropyl is stable, when in optical excitation, electrons of the nitrogen atom on the aminopropyl is prevented from being transferred to an NBD-APTS compound, fluorescence strength of the compound is enhanced according to a photoinduced electron transfer mechanism, recognition and detection of the DDT molecule are achieved by matching print sites and changing the fluorescence strength, photocatalysis of TiO2 is excited by changing an excitation wavelength, and thus degradation of the DDT molecule is achieved.

The invention belongs to the technical field of chemical sensing, and particularly relates to a new fluorescence detection method of tetracycline based on a zirconium-based MOF(Metal-Organic framework). By using the zirconium-based metal-organic framework (Zr-MOF) with good water and heat stability and excellent luminescent performance as a detection platform, selective adsorption enrichment and fluorescent response of the Zr-MOF on the tetracycline in a water body are utilized, so that high-sensitivity and high-selectivity detection on the tetracycline can be realized. Meanwhile, the detection method has a low detection limit. Compared with other detection methods of the tetracycline, the detection method disclosed by the invention has the advantages of simple and quick operation, no need of expensive and complicated instruments and equipment, and the like; therefore, the practicability is high, and the application range is wide. The fluorescent response of the zirconium-based MOF on the tetracycline is based on electron transfer between the zirconium-based MOF and the tetracycline, and fluorescence quenching on the zirconium-based MOF is caused by photoinduced electron transfer between the zirconium-based MOF and the tetracycline.

The invention provides a composite titanium dioxide photocatalyst, which consists of an inert metal micro-nano structure, a diamond-like film layer deposited on the inert metal micro-nano structure, and nano-titanium dioxide coated outside the diamond-like film layer, wherein The thickness of the diamond-like carbon film layer is 1-2 nanometers. In the present invention, the ultra-thin diamond-like film is coated on the inert metal micro-nano structure, and by preventing the photo-generated electrons of titanium dioxide from transferring to the metal, the surface plasmon effect of the metal micro-nano structure is stimulated to obtain a more pure metal micro-nano structure than the simple metal micro-nano structure. Strong enhanced electric field, thus greatly improving the photocatalytic efficiency of titanium dioxide, can be widely used in indoor pollutant removal, sterilization and degradation of organic dye pollutants.

The invention discloses a metal-organic framework material photosensitization titanium dioxide co-catalyst ADA-M/TiO2, which is obtained through simply mechanical grounding and mixing an MOFs material ADA-M and TiO2 according to a molar ratio of 0.4 percent to 40 percent, so that photoinduced electron transfer from the ADA-M to the TiO2 can be realized, and the aim of co-catalysis under visible light is achieved, wherein the ADA is an organic-ligand 9,10-diacrylic acid anthracene, and M is metal salt. The invention also discloses application of the metal-organic framework material photosensitization titanium dioxide co-catalyst ADA-M/TiO2 on high-efficiently catalytic degrading multiple cationic and anionic dyestuffs. A preparation method of the metal-organic framework material photosensitization titanium dioxideco-catalyst ADA-M/TiO2 provided by the invention is simple; an obtained binaryco-catalyst can be used for high-efficiently catalytic degrading the multiple cationic and anionic dyestuffs at room temperature and under visible light without additionally adding any oxidizing agent, has better stability and durability, and is green, environmental-friendly, and low in environment pollution abatement cost.

Compounds and methods for determining transmembrane potential, monitoring changes in transmembrane potential, and/or drug screening are provided. In one aspect, compounds of the invention have a structure according to the formula: E-M-A, wherein A is a fluorophore, selected from xanthenes, eoumarins, cyanines, bimanes, and difluoroboradizaindacenes, charged at physiological pH; M is a molecular wire; and E is a hydrophobic moiety, wherein A and E are capable of being involved in a photo-induced, intramolecular electron transfer that quenches the fluorescence of A in response to a voltage condition. When in use, compounds of the invention are membrane-impermeant and oriented within the cell membrane such that the charged moiety localizes at the outer leaflet of the lipid bilayer and the hydrophobic moiety and molecular wire associate with the hydrophobic portion of the lipid bilayer. The rate of electron transfer, fluorescence intensity, and quenching are altered in response to changes in transmembrane potential.

A light energy conversion system having a multiplicity of artificial photosynthetic reaction centers and exhibiting a high light-harvesting capability and charge separation capability, constructed by the use of a zinc porphyrin dendrimer supramolecular complex formed by the use of a coordinate bond. Using a zinc porphyrin dendrimer as a spherical zinc porphyrin oligomer, a supramolecule with pyridylnaphthalenediimide was constructed. With respect to the zinc porphyrin dendrimer/pyridylnaphthalenediimide supramolecule, when photoexcitation of the zinc porphyrin was realized, a charge-separated state was generated by photoinduced electron transfer and the lifetime thereof was strikingly long, up to 830 microseconds.

The invention belongs to the technical field of medicines and relates to a photosensitizer-hypoxia activated prodrug integrated prodrug. According to the invention, a photosensitizer and a hypoxia activated prodrug are connected through a bond which breaks under triggering by photo-induced electron transfer, a bond sensitive to active oxygen, or a bond which breaks under the triggering by photo-induced electron transfer and is sensitive or non-sensitive to active oxygen, so the photosensitizer and the hypoxia activated prodrug can be efficiently co-loaded and synchronously delivered. Pyropheophorbide a is used as a photosensitizer, PR104A is used as a hypoxia activated prodrug, a thioketal bond or monothioether bond or non-sensitive carbonate bond is employed for connecting pyropheophorbide with PR104A to synthesize an integrated prodrug, and then a self-assembled nanometer drug delivery system is prepared. According to the invention, a preparation process is simple; the drug loading capacity of the nanoparticles is high; the particle size of the nanoparticles is small and uniform, so the nanoparticles can be enriched at a tumor part through an EPR effect; while photodynamic therapy is conducted, the selective release of the hypoxia activated prodrug in the tumor is triggered through dual modes of PET and ROS; and the photodynamic therapy promotes the activation of the hypoxiaactivated prodrug, and significantly improves the synergistic anti-tumor effect of the photosensitizer and the hypoxia activated prodrug.

The novel photoelectrochemical nano-hybrid film fabricated by blending regioregular polyhexylthiophene (RRPHTh) with titanium oxide (TiO₂), Zinc oxide (ZnO) and nanodiamond (ND) nanoparticles on ITO coated glass plate, n-type silicon, and gold coated glass surfaces. The photoelectrochemical study reveals photoinduced electron transfer in nano-hybrid RRPHTh with donor and ND as acceptor providing a molecular approach to high-efficiency photoelectrochemical conversion properties. The ND-RRPHTh has shown promising morphological and photoelectrochemical properties than RRPHTh as well as TiO₂-RRPHTh and ZnO-RRPHTh nano-hybrid films.

The invention provides composite film for achieving efficient photoinduction electron transfer in a visible region, a preparation method and application, and belongs to the field of nanometer material science. The composite film is characterized in that transparent conductive oxide film serves as an electron extraction layer, citric acid serves as a carbon source, urea serves as a nitrogen source, nitrogen-doped carbon nanodots synthesized according to a microwave method serve as a photosensitive layer, and the photosensitive layer is compounded with a titanium dioxide electron separation layer of a nanometer mesoporous structure, so that the composite film is prepared. According to the composite film, with the help of oxygen molecules in air, efficient photoinduction charge separation from the carbon nanodots to titanium dioxide can be achieved, and the composite film can be applied to air purification and preparation of high-performance carbon-based solar cells, also shows the good dye light degradation characteristic in water, and can be used for water pollution control.

The invention belongs to the technical field of metalorganic framework composite materials, and particularly relates to a method for determining AA content in the mouse cerebrospinal fluid by using the RhB@MOF5 composite material. The method comprising the following steps: adding Fe3 to a RhB@MOF5 composite aqueous solution to form a RhB@MOF5/Fe3 composite aqueous solution, using the internal rateeffect and photoinduced electron transfer between Fe3 and RhB@MOF5, the quenching the fluorescence of the RhB@MOF5 composite material; then adding AA, wherein the AA reduces Fe3 to Fe2, which restores the fluorescence of RhB@MOF5 composite material, and determining its fluorescence spectrum change. The method of the invention is characterized in that the AA content in the cerebrospinal fluid of the mouse is highly selective and sensitive.

The invention provides a three-dimensional perylene type metal-organic framework material capable of stabilizing anion radicals and a using method of the metal-organic framework material for light-thermal conversion. Perylene bisimide is simply modified and can be coordinated with metals. The method is excellent in universality and simple and convenient to operate. The prepared metal-organic framework is stable in structure, stable anion radicals can be produced by virtue of a photoinduced electron transfer process, and other compounding or later modification is not needed. The radical stabilizing method has the advantages of being simple, economic and environmental-friendly. The produced anion radicals have extremely high light-thermal conversion property of 53.8%, the light-thermal conversion property is higher than that of the vast majority of infrared light-thermal conversion materials, and the anion radicals are stable in near-infrared light-thermal conversion property and can berepeatedly used. Therefore, the three-dimensional perylene type metal-organic framework near-infrared light-thermal conversion material and the method for stabilizing the anion radicals provided by the invention have potential commercial application prospects.

The invention discloses a meso-porous iridium pyridine heterogeneous catalyst, and a preparation method and an application thereof. The meso-porous iridium pyridine heterogeneous catalyst comprises a mercapto functionalized meso-porous foam silicon oxide matrix and an iridium pyridine catalyst covalently combined with the matrix, and active sites of the iridium pyridine catalyst are dispersed in the meso-porous tunnels of the matrix. The heterogeneous catalyst has a three dimensional tunnel structure. The preparation method of the heterogeneous catalyst is realized through a click chemical method, the heterogeneous catalyst can be well dispersed in a reaction system, grafted Ir<3+> active sides are dispersed on the inner walls of the pores of the heterogeneous catalyst, and the grafted Ir<3+> active sides are in mutually independent contact with a substrate, so the catalysis effect is realized, and mutual influences are avoided; the catalyst has good chemical and thermal stability, can eliminate reaction substrate diffusion influences, can be widely applied in photoinduced electron transfer reactions, and can be repeatedly used; and the preparation method has the advantages of simplicity, wide sources of raw materials, convenient and controllable operation, low cost, and easy large-scale enforcement.

The invention discloses a perylene bisimide derivative nano-material and a preparation method and application thereof, the nano-material has specific selective response to sarin poison gas, and the nano-material is of a banded nano-structure formed by self-assembly of construction molecules through pi-pi stacking; according to the nanometer material, the construction molecules are subjected to crosslinking, interconnection or polymerization to form a net structure, the interconnected network structure provides a high-speed transmission channel for electron transfer among the molecules, rapid photoinduced electron transfer is further ensured, and the detection sensitivity of the nanometer material is improved; the high fluorescence quantum yield is beneficial to further improvement of the detection sensitivity, and the lowest detection limit of sarin poison gas is greatly reduced. The nano material has no fluorescent response to phosgene, soman poison gas, tower collapse poison gas, chlorine, mustard gas and the like, has good anti-interference capability, realizes specific and high-sensitivity detection of sarin poison gas, and has good application prospects.

The invention discloses a composite nano-probe based on N-Ti<3>C<2>QDs and o-phenylenediamine oxide, and discloses a ratio fluorescence detection method of the probe for H<2>O<2> and xanthine. The probe is the composite nano-probe, which is formed by bonding N-Ti<3>C<2>QDs to DAP through pi-pi conjugation and hydrogen bonds and used for ratio fluorescence detection of H<2>O<2> or xanthine. According to the invention, a dual-emission reverse ratio fluorescent sensing platform of H<2>O<2> based on photo-induced electron transfer (PET) is established by using quantum dots synthesized by a MXene two-dimensional material for the first time; furthermore, on the basis of the effect of xanthine generating H<2>O<2> under specific catalysis of xanthine oxidase, ratio fluorescence detection of xanthine is realized; and the detection method in the invention has the advantages of being free from labelling, high in sensitivity, high in accuracy and low in cost detection, and has good application prospect.

Metallopolymers composed of polymers and catalytically active diiron-disulfide ([2Fe-2S]) complexes are described herein. [FeFe]-hydrogenase mimics have been synthesized and used to initiate polymerization of various monomers to generate metallopolymers containing active [2Fe-2S] sites which serve as catalysts for a hydrogen evolution reaction (HER). Vinylic monomers with polar groups provided water solubility relevant for large scale hydrogen production, leveraging the supramolecular architecture to improve catalysis. Metallopolymeric electrocatalysts displayed high turnover frequency and low overpotential in aqueous media as well as aerobic stability. Metallopolymeric photocatalysts incorporated P3HT ligands to serve as a photosensitizer to promote photoinduced electron transfer to the active complex.

The invention discloses a doxorubicin fluorescence detection method based on carboxylated chitosan/dithiothreitol-gold nanoclusters. The doxorubicin fluorescence detection method based on the carboxylated chitosan/dithiothreitol-gold nanoclusters uses the effect that strong photoinduced electron transfer occurs after the specificity interaction of the gold nanoclusters and doxorubicin to cause thequenching of the fluorescence of the gold nanoclusters, thereby realizing the determination of doxorubicin. The linear range of doxorubicin determination is 0.05[Mu]mol/L to 2[Mu]mol/L, and the minimum detection limit is 0.005[Mu]mol/L. The gold nanoclusters used in the new detection method are simple and easy to prepare, and the new detection method has the advantages of simple operation, shortdetection time, high sensitivity and strong specificity, and is easy to popularize and use.

The invention relates to a method for targeted detection of H2S in lysoome through carbon quantum dots, and belongs to the technical field of a biosensor and ion recognition. The fluorescence intensity of a synthesized carbon quantum dot CD-dopa-morph fluorescent probe and H2S in a 575 nm position can be obviously enhanced through photoinduced electron transfer. The H2S detection lowest limit of the carbon quantum dot fluorescent probe reaches 70nM. The carbon quantum dot fluorescent probe has the advantages that the synthesis method is simple; the biocompatibility is good; the cell toxicity is low; the detection sensitivity is high; the detection is fast; the signal is stable; the possibility is provided for the realization of clinic detection of H2S in cytolysosome.

The invention relates to an immobilized algae cell bioelectrode and a usage method thereof. The bioelectrode is prepared by immobilizing algae cells on a planar porous electrode material by using a sol-gel method. The prepared bioelectrode is used as a work electrode and constitutes a three-electrode system with a counter electrode and a reference electrode, an electronic mediator is added in electrolyte and an external voltage is applied so as to perform light response test on the electrode. Electron transfer between an algae photosynthetic system and an electrochemical system can be realized by using the prepared bioelectrode, a light current of 94.2 microamperes which is 25 times that of an algae cell suspension system can be obtained. No technology used for light current researches of preparing the bioelectrode by using silica gel immobilized microalgaes is reported internationally. The bioelectrode can realize high-efficiency couple between the biological photosynthetic system and the electrochemical system, characterizes a photoinduced electron transfer process of a biosystem, realizes direct photoelectric or light energy-hydrogen energy transfer, and has the advantage of high efficiency with low cost, and is simple and practicable.

The invention discloses a model compound for the research on blue light receptor photoinduced electron transfer and a preparation method thereof. The model compound has a structural general formula shown by formula (I), and n is an integer not smaller than 1. The preparation method comprises the following steps: sequentially preparing end-(N-carbobenzoxy) fatty acid, 2-(end-(N-carbobenzoxy) fatty acid acylamino)-3-(1H- indolyl-3) methyl propionate, 2-(end-amino fatty acid acylamino)-3-(1H- indolyl-3) methyl propionate, 7,8- dimethyl-10- glyoxyl-isoalloxazine, and the model compound for the research on blue light receptor photoinduced electron transfer. The model compound disclosed by the invention adopts flavin as a photosensitizer, a spacer arm molecule with a proper length is connected with tryptophan serving as an electron donor through a covalent bond, and the preparation method is short in route, low in cost, simple and convenient and high in yield. The formula is described in the description.

The invention discloses an enhanced azo Salen Schiff base fluorescent probe and synthesis and application thereof, belonging to the technical field of fluorescent probes. The chemical formula of the fluorescent probe is C39H34N8O7, and the structural formula of the fluorescent probe is as shown in the specification. The fluorescent probe has good selectivity on Al <3+>, good linear relation, highsensitivity, strong fluorescence response, low detection limit and low cost, and can be widely applied to detection of Al<3+> ions in an environment. Compared with the prior art, the fluorescent probeof the invention has the advantages that more than one time of coordination sites can be provided; the fluorescent probe is more easily coordinated with Al<3+> to form a binuclear complex with a plurality of coordination sites; and molecular plane rigidity is enhanced after coordination, so the photoinduced electron transfer effect of Schiff base nitrogen atoms is inhibited, and a strong chelating fluorescence enhancement effect is generated. The synthesis method of the probe is simple, and has high yield, and reaction conditions are easy to control.