Patents
Literature
Patsnap Copilot is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Patsnap Copilot

392results about How to "Long fluorescence lifetime" patented technology

Method for highly sensitive quantitative detection of quantum dot fluorescence immunochromatographic assay

ActiveCN102520165ASensitive quantitative detection fastRealize detectionMaterial analysisCritical illnessLinear range
The invention discloses a method for highly sensitive quantitative detection of quantum dot fluorescence immunochromatographic assay. The method includes: building a fluorescence immunochromatographic assay test strip on the basis of optimizing the structure of the test strip and components by the aid of excellent fluorescent characteristics of quantum dots and by means of combining quantum dot fluorescence labeling technology and immunochromatographic assay; detecting fluorescence signal strength of a quantitative belt and a quality control belt by the aid of a fluorescence quantometer and correcting the fluorescence strength of the quantitative belt by the aid of the quality control belt after immunochromatographic assay of the test strip; and further quantitatively detecting analyte according to a standard curve obtained by the fluorescence quantometer. The method is simple, rapid, accurate, low in cost and quite high in sensitivity. Compared with a conventional colloidal gold immunochromatographic assay method, the method has the advantages of fine labeling stability, low non-specificity, high sensitivity, wide linear range and accuracy in quantization. The method is applicable to samples such as blood samples, urine samples, spittle, excrement and the like, and can be applied to detection of critical illness, poison, food safety and the like.
Owner:BEIJING KANGMEI TIANHONG BIOTECH

Fluorescent immunochromatography method for whole quantitative detection of C-reactive protein and reagent kit thereof

ActiveCN102539785ASolve the backgroundSolve the signal indistinguishableBiological testingFluorescence/phosphorescenceBasic levelQuantum dot
The invention discloses a fluorescent immunochromatography method for whole quantitative detection of C-reactive protein and a reagent kit thereof. The fluorescent immunochromatography method for the whole quantitative detection of the C-reactive protein (CRP) utilizes excellent fluorescent characteristics of quantum dots, and combines double-color marking technology and immunochromatography technology to achieve fluorescent quantitative detection on the basis of optimizing each constituent elements of test paper. Compared with a conventional colloidal gold immunochromatography method, the fluorescent immunochromatography method for the whole quantitative detection of the CRP has the advantages of being good in stability, low in non-specificity, high in flexibility, wide in linear range and accurate in quantifying. The reagent kit of the fluorescent immunochromatography method can perform the whole quantifying and can simultaneously predict and evaluate infectious diseases, antibiotic effects and cardiovascular and cerebrovascular diseases. The fluorescent immunochromatography method for the whole quantitative detection of the CRP and the reagent kit of the fluorescent immunochromatography method are suitable for various-level hospitals, and particularly contribute to wide popularization in basic-level hospitals and clinics.
Owner:SHENZHEN KANGMEI BIOTECH

Test strip detection system

A test strip detection system, comprising a test strip card (1) and a detection device (2); the test strip card (1) comprises a card box (16), a built-in test strip (15) and an electronic label (20) matched with the built-in test strip (15); the electronic label (20) stores parameters such as the standard working curve of an object to be detected and the like; the detection device (2) comprises an optical system (3), a photoelectric detector (4), an analog / digital converter (5), a data processing device (6), an electronic label read-write module (10) with an aerial (11), a voice module (34), a cell box (7) and an output display device (8). The system further comprises a wireless communication module (12) and a wireless network system (13) connected with the wireless communication module (12) and comprising a remote server (14). The data processing device (6) calculates a sample detection result according to the characteristic frequency optical signals transmitted by a test strip detection band (27) and a quality control band (28) in combination with an electronic label (20) transmission parameter; the detection result is displayed on the output display device (8); the voice module (34) vocally prompts the detection result at the same time; the detection result is transmitted to the remote server (14) via the wireless communication module (12) for data management and information feedback.
Owner:CHENGDU LINGYU BIOTECH

Infrared-excited fluorescence-lifetime-adjustable up-conversion nanocrystal material and preparing method thereof

The invention belongs to the technical field of nanometer biological materials and particularly relates to an infrared-excited fluorescence-lifetime-adjustable up-conversion nanocrystal material and a preparing method thereof. The fluorescence nanometer material is a core-shell structure nanocrystal material with one core and two shell layers, and is composed of the up-conversion fluorescent center core, the energy transmission layer and the energy absorption layer. The up-conversion fluorescent center core absorbs exciting light with the specific wavelength and emits visible light; the energy transmission layer transmits energy between the energy absorption layer and a visible light emitting layer, and the fluorescence lifetime of the material is regulated by changing the thickness of the energy transmission layer; the energy absorption layer absorbs the energy of infrared-excited light and transfers the energy to the energy transmission layer. Through the design of the three-layer structure, the energy transmission process from Nd<3+ >to Yb<3+> to Tm<3+> and the energy transmission process from Nd<3+> to Yb<3+> to Er<3+> are achieved, and in addition the fluorescence lifetime of the material can be regulated and controlled just by changing the thickness of the middle layer. The material can be applied to the fields of analysis and detection.
Owner:FUDAN UNIV

Fluorescence immunochromatographic assay method for quantitatively detecting heart fatty acid binding protein and kit for quantitatively detecting same

ActiveCN102520194ASolve the backgroundSolve the signal indistinguishableBiological testingBlood plasmaBiology
The invention discloses a fluorescence immunochromatographic assay method for quantitatively detecting hFABP (heart fatty acid binding protein) and a kit for quantitatively detecting the same. The fluorescence immunochromatographic assay method for quantitatively detecting the hFABP realizes quantitative fluorescence detection on the basis of optimizing components of a test strip by the aid of excellent fluorescent characteristics of quantum dots and by means of combining bicolor labeling technique and immunochromatographic assay. Compared with a conventional colloidal gold immunochromatographic assay method, the fluorescence immunochromatographic assay method has the advantages of fine labeling stability, low non-specificity, high sensitivity, wide linear range and accuracy in quantization. The kit is used for quantitatively detecting the hFABP, can be used for simultaneously detecting whole blood, blood serum and plasma samples, serves as a simple, accurate, specific and inexpensive detecting tool for early screening and prognosis evaluation of acute myocardial infarction, is applicable to hospitals at all levels, and is particularly beneficial to wide popularization in primary hospitals and clinics.
Owner:SHENZHEN KANGMEI BIOTECH

Immunofiltration assay fluorescent quantitative detection method based on high-sensitivity quantum dot

The invention discloses an immunofiltration assay fluorescent quantitative detection method based on a high-sensitivity quantum dot; the immunofiltration assay fluorescent quantitative detection method comprises the following steps of: constructing a fluorescence immunofiltration array device by using the excellent fluorescent characteristic of the quantum dot in combination of a quantum dot fluorescence labeling technology and an immunofiltration array technology on the basis of optimizing constituent parts for the immunofiltration assay; and after immunofiltration array, detecting the strenght of fluorescent signals of the quantum dot and a quality control dot by using a fluorescence quantometer, correcting the fluorescence strenght of the quantum pot by using the quality control dot, and further realizing the quantitative detection of a tested object according to a standard curve obtained by using the fluorescence quantometer. The method is simple, rapid, accurate, low in cost and high in sensitiveness. Comapred with the conventional collodial gold immunofiltration array method, the immunofiltration assay fluorescent quantitative detection method has the advantages of good labeling stability, low non-specificity, high sensitivity, wide linear range and accurate quantification. The method is suitable for samples such as serums, urine, spittle, excrement and the like and can be applicable to the detection of serious illness, poisons, food safety and the like.
Owner:BEIJING KANGMEI TIANHONG BIOTECH

Acridone derivatives as labels for fluorescence detection of target materials

Disclosed are new acridone dye derivatives having characteristic fluorescence lifetimes. Also disclosed are methods for labelling target biological materials employing the acridone dyes and use of the labelled materials in biological assays. The acridone derivatives have the following structure:in which Z1 and Z2 represent the atoms necessary to complete one ring, two fused ring, or three fused ring aromatic or heteroaromatic systems, each ring having five or six atoms selected from carbon atoms and optionally no more than two atoms selected from oxygen, nitrogen and sulphur; R2, R3, R4 and R5 are selected from hydrogen, halogen, amide, hydroxyl, cyano, nitro, mono- or di-nitro-substituted benzyl, amino, mono- or di-C1-C4 alkyl-substituted amino, sulphydryl, carbonyl, carboxyl, C1-C6 alkoxy, acrylate, vinyl, styryl, aryl, heteroaryl, C1-C20 alkyl, aralkyl, sulphonate, sulphonic acid, quaternary ammonium, the group -E-F and the group —(CH2—)nY; R1 is selected from hydrogen, mono- or di-nitro-substituted benzyl, C1-C20 alkyl, aralkyl, the group -E-F and the group —(CH2—)nY; where E is a spacer group, F is a target bonding group; Y is selected from sulphonate, sulphate, phosphonate, phosphate, quaternary ammonium and carboxyl; and n is an integer from 1 to 6. The invention also relates to a set of different fluorescent acridone dye derivatives, each dye having a different fluorescence lifetime, the set of dyes being particularly useful for multiparameter analysis.
Owner:TTP LABTECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products