39results about How to "Narrow emission peak" patented technology

The invention discloses a photoluminescent nano particle as well as a preparation method and an application thereof. The photoluminescent nano particle is composed of a carboxyl-containing copolymer matrix material and a rare earth fluorescent dye dispersed in the matrix material. The preparation method of the fluorescent nano particle comprises the following steps: dissolving the rare earth compound fluorescent dye and the copolymer in an organic solvent which is capable of being miscible with water; and adding the solution in water, so that the fluorescent nano particle is formed by utilizing a coprecipitation-self assembly process. The fluorescent nano particle has the advantages of excellent long wave excitation luminescence property and good stability, and has a surface carboxyl group for coupling biomolecules. A biological probe based on the fluorescent nano particle has a wide application prospect in the aspects of high-sensitivity fluorescent immunoassay, biological imaging and the like.

The invention discloses ultraviolet-blue ray excitated aluminate-base narrow-band green fluorescent powder. A chemical formula of the aluminate-base narrow-band green fluorescent powder is Sr(Mg1-xMnx)yAl12-2yO19-2y, wherein Mn is divalent, x is more than 0 and less than or equal to 0.50, and y is more than or equal to 0 and less than or equal to 1.0. The invention further discloses a preparationmethod of the ultraviolet-blue ray excitated aluminate-base narrow-band green fluorescent powder. The excitation wavelength of the fluorescent powder is 350nm-475nm in an ultraviolet-blue ray region and can be well matched with commercial ultraviolet-blue ray LED chips; the fluorescent powder is narrow in emission peak, high in color purity and excellent in heat stability and has a very wide colorrange; and the synthetic temperature is low, the synthetic process is simple, and the fluorescent powder is stable in chemical performance and pollution-free and has very high practical and application values in the field of fluorescent powder for new-generation LCD backlight sources.

The invention relates to a near-infrared truxene-based conjugate dual-BODIPY fluorescent dye and a preparation method thereof. The fluorescent dye is synthesized by virtue of Knoevenagel condensation reaction of a BODIPY derivative and dialdehyde-containing truxene under the catalysis of p-toluenesulfonic acid and piperidine. The preparation method has the beneficial effects of simple reaction steps, mild reaction conditions and relatively good selectivity. The fluorescent dye has excellent physical properties of relatively high molar extinction coefficients, good solubility and light stability and the like, the highest electronic absorption spectrum red shift reaches above 650nm, the fluorescence emission wavelength reaches 680nm, and the fluorescent dye has very high application prospects. The fluorescent dye has good potential application prospects in the fields of cell imaging, bio-labeling or photoelectric materials and the like.

The invention discloses a fluorine-boron fluorescent dye as well as a preparation method and application thereof, wherein the structure of the fluorine-boron fluorescent dye is shown as a formula (I) or a formula (II), in the formula (I) and the formula (II), R1 is H or halogen; R2 is CN; R3, R4, R5 and R6 are independently selected from H, halogen, C1-C6 alkyl or C1-C6 alkoxy; V, W, X, Y and Z are independently CH or N, and when V, W, X, Y or Z is N, N has no substituent group. According to the fluorine-boron fluorescent dye and the preparation method thereof, the maximal fluorescence emission wavelength of the fluorine-boron fluorescent dye is 518-600nm, and the fluorine-boron fluorescent dye also has excellent fluorescence quantum yield and Stokes shift, which shows that the fluorine-boron fluorescent dye has good application prospect in the bioanalysis fields of fluorescence labeling, bioimaging and so on; meanwhile, the preparation method is simple in steps, and raw materials can be obtained easily.

The invention relates to a medical immunodetection method and in particular relates to a method for detecting a Japanese encephalitis virus (JEV) by an immunological method by using a quantum dot labelled immunochromatographic test strip. The quantum dot labelled immunochromatographic test strip is characterized in that a glass cellulose membrane A, a glass cellulose membrane B of a quantum dot labelled JEV IgG (immunoglobulin G) monoclonal antibody, a nitrocellulose membrane and absorbent paper are stuck to a plastic board from bottom to top in sequence, wherein one end of the nitrocellulose membrane has a JEV polyclonal antibody and a rabbit anti-mouse second antibody, thereby forming a detection zone T and a quality control zone C; the quantum dot labelled JEV IgG monoclonal antibody is arranged at the other end of the glass cellulose membrane B, corresponds to the detection zone T and the quality control zone C and is arranged at one end of a sampling point. The detection sensitivity of the method is about 1000 times higher than that of the detection method frequently used at present.

The invention discloses ultraviolet-blue ray excitated aluminate-base narrow-band green fluorescent powder. A chemical formula of the aluminate-base narrow-band green fluorescent powder is Sr(Mg1-xMnx)yAl12-2yO19-2y, wherein Mn is divalent, x is more than 0 and less than or equal to 0.50, and y is more than or equal to 0 and less than or equal to 1.0. The invention further discloses a preparationmethod of the ultraviolet-blue ray excitated aluminate-base narrow-band green fluorescent powder. The excitation wavelength of the fluorescent powder is 350nm-475nm in an ultraviolet-blue ray region and can be well matched with commercial ultraviolet-blue ray LED chips; the fluorescent powder is narrow in emission peak, high in color purity and excellent in heat stability and has a very wide colorrange; and the synthetic temperature is low, the synthetic process is simple, and the fluorescent powder is stable in chemical performance and pollution-free and has very high practical and application values in the field of fluorescent powder for new-generation LCD backlight sources.

The invention relates to a medical immunodetection method and particularly relates to a method for using quantum-dot labeled immunochromatography test paper to detect mumps virus by an immunological method. The quantum-dot labeled immunochromatography test paper is characterized in that a plastic board is stuck with a glass cellulose membrane A, a glass cellulose membrane B of a quantum-dot labeled mumps virus IgG monoclonal antibody, a nitrocellulose membrane and water absorbing paper from bottom to top in sequence, wherein one end of the nitrocellulose membrane is provided with mumps virus polyclonal antibody and rabbit antimouse second antibody so as to form a detecting band T and a quality control band C; the quantum-dot labeled mumps virus IgG monoclonal antibody is positioned at one end of the glass cellulose membrane and corresponds to the detecting band T and the quality control band C, and the quantum-dot labeled mumps virus IgG monoclonal antibody is positioned at one end of a sampling point. The method has the advantage that the detection sensitivity is about 1000 times higher than that of the commonly-used method.

The invention discloses a class of fluorescent nanoparticles and a preparation method and an application thereof. The fluorescent nanoparticle comprises matrix material and fluorescent dye dispersed in the matrix material, wherein the matrix material is the compound composed of hydrophobic polymer main chain of which is hydrocarbon chain, organo-siloxane and organosilicon-polymer, and the fluorescent dye is rare earth complex with photoluminescence performance. The preparation method of the fluorescent nanoparticle comprises the following steps: dissolving rare earth complex, hydrophobic polymer and compound RSi (OR') 3 into organic solvent miscible with water; adding the mixture into aqueous solution containing surfactant; using precipitation and hydrolytic condensation reaction to form nanoparticles. The nanoparticle of the invention has favourable luminous performance and favourable stability, can have a silicon oxide shell and a surface functional group and can be used for bonding biomolecules; biological probes based on the fluorescent nanoparticle have wide application prospects on the aspects of high-sensitivity fluorescence immunoassay, imaging and the like.

The invention relates to a medical immunodetection method, and particularly relates to a method for detecting hepatitis c virus by quantum-dot-marked immunochromatographic test paper through immunology. According to the quantum-dot-marked immunochromatographic test paper, a glass cellulose membrane A, a glass cellulose membrane B of a quantum-dot-marked hepatitis c virus monoclonal antibody, a nitrocellulose membrane and absorbent paper are sequentially adhered to a plastic plate from top to bottom, wherein one end of the nitrocellulose membrane is provided with a hepatitis c virus polyclonal antibody and a rabbit antimouse second antibody to form a detection band T and a detection band C; the quantum-dot-marked hepatitis c virus monoclonal antibody is located at one end of the glass cellulose membrane B and corresponds to the detection band T and the detection band C, and the quantum-dot-marked hepatitis c virus monoclonal antibody is located at the end of a sampling point. The sensitiveness of the method is about 1000 times higher than that of a colloidal gold method.

The invention relates to a medimmune inspection method, and particularly relates to quantum dot-labeled immunochromatographic test paper, and a method for detecting rubella virus by adopting an immunological method. According to the quantum dot-labeled immunochromatographic test paper, a glass cellulose membrane A, a quantum dot-labeled rubella virus IgG monoclonal antibody glass cellulose membrane B, a cellulose nitrate membrane and absorbent paper are sequentially bonded on a plastic board from bottom to top, wherein a rubella virus polyclonal antibody and a rabbit-anti-mouse secondary antibody are arranged on one end of the cellulose nitrate membrane so as to form an inspection strip T and a quality control strip C; a quantum dot-labeled rubella virus IgG monoclonal antibody is located at the other end of the glass cellulose membrane B and corresponds to the inspection strip T and the quality control strip C, and the quantum dot-labeled rubella virus IgG monoclonal antibody is located at one end of a sample feeding point. The inspection sensitivity of the method is higher than of the currently used method by about 1000 times.

The invention relates to a medical immunodetection method and particularly relates to a method for using quantum-dot labeled immunochromatography test paper to detect hepatitis E virus by an immunological method. The quantum-dot labeled immunochromatography test paper is characterized in that a plastic board is stuck with a glass cellulose membrane A, a glass cellulose membrane B of a quantum-dot labeled hepatitis E virus IgG monoclonal antibody, a nitrocellulose membrane and water absorbing paper from bottom to top in sequence, wherein one end of the nitrocellulose membrane is provided with hepatitis E virus polyclonal antibody and rabbit antimouse second antibody so as to form a detecting band T and a quality control band C; the quantum-dot labeled hepatitis E virus IgG monoclonal antibody is positioned at one end of the glass cellulose membrane and corresponds to the detecting band T and the quality control band C, and the quantum-dot labeled hepatitis E virus IgG monoclonal antibody is positioned at one end of a sampling point. The method has the advantages that high specificity of immunoreactions and the fluorescence characteristic of quantum dots are combined, so that the detection sensitivity is about 1000 times higher than that of the current commonly-used detection method.