75results about How to "Long emission wavelength" patented technology

The invention relates to a dark red/near-infrared multifunctional aggregation-induced light-emitting material, a preparation method and application thereof. According to the dark red/near-infrared multifunctional aggregation-induced light-emitting material, a pyridine ring in the molecular structure endows the molecule with electropositivity, and meanwhile, the molecule has appropriate lipo-hydropartition coefficient (with ClogP being greater than 3 and less than 5) and space structure, and is beneficial to combination with gram-positive bacteria. During co-culture of the molecule with bacteria, specific "lightening" imaging of gram-positive bacteria can be realized; the strong electron donating (D)-electron withdrawing (A) effect of the molecule itself causes absorption and emission wavelength red shift of the molecule, thus having dark red/near-infrared fluorescence emission and strong ROS generation capacity. Meanwhile, the aggregation-induced light-emitting material provided by the invention can efficiently kill gram-positive bacteria.

The invention discloses a thermosensitive liposome capable of conducting magnetic-heat release. The thermosensitive liposome consists of a phospholipid liposome which is constructed by a thermosensitive material and magnetic nanoparticles covered in the phospholipid liposome, wherein phase-transition temperature of the phospholipid liposome is at 40-51 DEG C; the magnetic nanoparticles are superparamagnetic ferriferrous oxide particles; the magnetic nanoparticles can become heated in a (high-frequency) alternating magnetic field, and the phospholipid liposome is heated up to the phase-transition temperature and substances in the phospholipid liposome are released; and near-infrared fluorescence quantum dots are also covered in the phospholipid liposome. The thermosensitive liposome provided by the invention, in which the magnetic nanoparticles are covered, has a magnetic-heat effect, and the thermosensitive liposome can achieve local heating to result in structural damage in the alternating magnetic field, so that effective ingredients in the thermosensitive liposome are released; the thermosensitive liposome has the characteristic of being high in controlled-release precision; and in the combination with the near-infrared fluorescence quantum dots which serve as a tracing ingredient, the problem that the magnetic thermosensitive liposome, when entering a body, is difficult to represent is effectively solved, and a tracing effect is achieved.

The invention belongs to the field of fluorescent dyes and laser dyes, and relates to coumarin fluorescent dyes and laser dyes, in particular to pyrazoline naphthyridine benzocoumarin fluorescent dye derivatives, a synthesis method of the same, and application of the same. The pyrazoline naphthyridine benzocoumarin fluorescent dye derivatives have longer emission wavelength and extremely high luminous efficiency, and the fluorescence quantum efficiency of the derivatives is approximately 100 percent; at the same time, a luminescent material of the derivatives has excellent thermo, photo and electrochemical stability, and can be used as fluorescent dyes, laser dyes, organic electroluminescent materials, fluorescent labeling materials, fluorescent chemosensitive materials and the like. The pyrazoline naphthyridine benzocoumarin fluorescent dye derivatives have a structure shown in a formula (I) or a formula (II).

The invention discloses an axially-chiral fluorescence dye compound having a characteristic of aggregation-induced luminescence. The invention further discloses a preparation method of the compound. The compound disclosed by the invention has the advantages of being simple and convenient to synthetize, high in product yield, simple to purify and the like, the synthetized compound concurrently has the characteristics of an axially-chiral structure of binaphthol and the characteristics of fluorescence of a coumarin structure, has the characteristics of long transmitted wave length, larger stocks shift and aggregation-induced luminescence, presents yellow fluorescence at solid state, and has potential application in the field of organic luminescent materials and fluorescence test.

There is herein described a composite ceramic wavelength converter having a first phase of an α-SiAlON:Eu phosphor and a second phase of a β-SiAlON:Eu phosphor. The converter may be used in a phosphor-converted light emitting diode to form a light source having a correlated color temperature (CCT) from 2000K to 4500K.

The invention discloses a 4-N substituted anthracene pyridone fluorescent dye and a preparation method and application thereof. The compound has the structural general formula I, wherein in the general formula I, n is an integer from 1-10; and R is selected from hydrogen atom, methyl, hydroxyl, amino group, dimethylamino group, trimethyl ammonium halide group and guanidine hydrochloride group. The 4-N substituted anthracene pyridone fluorescent dye disclosed by the invention is simple to synthesize, and has good light stability, relatively long emission wavelength and good cellular membrane permeability. Therefore, the invention also aims to provide application of the 4-N substituted anthracene pyridone fluorescent dye in biological dyeing, and the 4-N substituted anthracene pyridone fluorescent dye can be used for dyeing fixed cells, living cells and biological tissues.

The invention discloses a beta-phenanthrene azaBODIPY dye and a preparation method and application thereof. The structural formula of the beta-phenanthrene azaBODIPY dye is as shown in the formula (I) (please see the formula in the description), wherein R1 is alkoxy groups of C1-C6, R2 and R4 are independently selected from alkoxy groups of C1-C6 or alkyl groups of C1-C6, and R3 and R5 are independently selected from hydrogen or alkoxy groups of C1-C6. By means of the design, the prepared beta-phenanthrene azaBODIPY dye of the structure shown in the formula (I) has large absorption wavelength in actual use, narrow absorption peaks and emission peaks and excellent molar absorption coefficient, and thereby having potential application in optical sensors and photoacoustic imaging.

The invention discloses a novel compound and a preparation method and application thereof. Specifically, the invention provides a 2-(2 '-hydroxyphenyl) benzoxazole compound which has an excited stateintramolecular proton transfer and aggregation-induced emission characteristic and has a skeleton structure as shown in a general formula I. In the general formula I, R2 is independently selected fromhydrogen, an aldehyde group or an electron-withdrawing unit conjugated with a benzene ring through double bonds; the invention provides a preparation method of a 2-(2 '-hydroxyphenyl) benzoxazole compound. In addition, the invention also provides an application of the 2-(2 '-hydroxyphenyl) benzoxazole compound containing the nitrogen positive ion structure in living cell mitochondrion imaging. The 2-(2 '-hydroxyphenyl) benzoxazole compound with excited state intramolecular proton transfer and aggregation-induced emission effects has a good application prospect in the fields of photoelectricity, sensing, biomedicine and the like.

The invention belongs to the technical field of biological materials, and particularly relates to a near-infrared window II emission type fluorescent dye as well as a preparation method and application thereof. The near-infrared fluorescent dye provided by the invention has the advantages of being large in molar extinction coefficient, long in absorption and emission wavelength and wide in adjustable range, and therefore the dye can be applied to deep-tissue multi-channel imaging, fluorescent encoding microspheres and the like; and in addition, the dye is not liable to generate solvatochromismin a polar solvent, has better stability in water compared with an existing common near-infrared window II heptamethine cyanine fluorescent dye and has very good chemical stability within a relatively large acid-base range.

The invention discloses a near-infrared fluorescent probe, preparation and an application of the near-infrared fluorescent probe in detection of transthyroxine tetramer protein. The structural formula of the near-infrared fluorescent probe is shown as a formula (I). The preparation method comprises the following steps: adding 2-aldehyde-6-dimethylaminoquinoline, 2-acetonitrile benzothiazole and tetrabutylammonium bromide into ethanol, carrying out a reflux reaction under the conditions of sealing and oil bath at 80 +/-5 DEG C, cooling to room temperature after the reaction is finished, standing to separate out a solid, carrying out suction filtration, and washing to obtain the near-infrared fluorescent probe. The fluorescent probe prepared in the invention has near-infrared emission wavelength, and can be used for detecting the content of transthyretin tetramer protein and diagnosing transthyretin familial amyloidosis.

The invention relates to a compound with a general formula I, wherein 1-pyrene butylamido is substituted at pyridine ring 2, 3 or 4 site; -B(OH)2 is substituted at benzene meta or para site; and X is F, Cl, Br or I. the compound can be used as a fluorescent molecular probe in carbohydrate detections. The compound has good water solubility, high fluorescent intensity, and highly efficient carbohydrate detection performance. The invention also relates to an application of the compound represented by the formula I as a fluorescent molecular probe in detecting carbohydrates. The invention also relates to a method for applying the compound represented by the general formula I in detecting carbohydrates and especially water-soluble total sugar in tobacco. The detection method provided by the invention is simple and economical, and has the advantages of good selectivity and high sensitivity.

The invention discloses a fluorescent probe with the characteristic of charge transfer, and a preparation method and an application thereof, belonging to the fields of chemical synthesis, chemical analysis and biological analysis. According to the invention, the structure of the probe comprises the parts of electron-donating triphenylamine and electron-deficient quinoline salt, so the probe has the property of intramolecular charge transfer. The fluorescent probe has the following advantages: the synthetic route has high operability; the purification method is simple; the preparation cost is low; and good market competitiveness is obtained. The fluorescent probe has stable structure and low fluorescence background, wherein the fluorescence enhancement exceeds one hundred times after specific binding of the fluorescent probe with a G-quadruplex. Through fluorescence spectrum, a secondary structure of a DNA sample can be rapidly detected, and the disadvantages like high price, long cycle and complicated technical operation in the prior art are overcome.

The invention discloses a cell nucleolus imaging red fluorescent carbon dot and a preparation method and application thereof. The red fluorescent carbon dot is prepared from the following raw materials in parts by weight: 1 part of Congo red and 1-10 parts of p-phenylenediamine. The fluorescent carbon dot is prepared by taking p-phenylenediamine and Congo red as raw materials and adopting a one-step hydrothermal method, and the carbon dot prepared by the invention can realize rapid, no-clean, long-time and light-stable (anti-bleaching) imaging of cell nucleuses and nucleuses of mammalian cells, and can also be applied to living cell nucleolus fluorescence imaging of model animals (such as zebra fish and nematodes). In addition, the carbon dot also has the advantages of low preparation cost, good water dispersibility, low cytotoxicity, large Stokes shift and the like, and can replace the commercialized nucleolus fluorescent probe which is widely used at present.

The invention relates to the technical field of photochemical detection and analysis, and discloses a fluorescent compound for detecting viscosity of oil displacement of tertiary oil recovery, and a preparation method and application of the fluorescent compound. The fluorescent probe is 2-(4-bis(4-methoxyphenyl)amino)phenyl)anthracene-9,10-dione (TPAMD). The probe compound disclosed by the invention is composed of groups with an aggregation-induced emission characteristic and anthraquinone groups with an electron-withdrawing effect, and thus has an aggregation-induced emission characteristic and an intramolecular charge transfer characteristic simultaneously. The probe is easy to prepare, is high in yield, has good viscosity responsiveness, and has relatively good linear response. The probe can be used in complex solvent environments, has good resistance to solvent perturbation, can be used to achieve detection of viscosity of chemical displacement agents in the oil production field, and the method has an analysis and detection potential for various viscosity-sensitive fields such as chemistry, food, environment and the like.

The invention provides a novel mercury ion fluorescent probe based on rhodamine B as well as a preparation method and application thereof. The structural formula of the novel mercury ion fluorescent probe based on rhodamine B is shown in the specification, and the preparation method comprises the following steps: preparing rhodamine B acyl chloride by adopting rhodamine B; carrying out a reactionbetween the obtained rhodamine B acyl chloride and N,N-dimethyl selenourea in a solvent containing triethylamine; removing the solvent through reduced pressure distillation, and carrying out extraction, rotary evaporation and column chromatography separation to obtain the novel mercury ion fluorescent probe based on rhodamine B. According to the invention, rhodamine B is used as a fluorescent group and N,N-dimethyl selenourea is used as a recognition group to synthesize a novel mercury ion fluorescent probe based on rhodamine B, which has strong selectivity to mercury ions and high sensitivity, and strong anti-interference capability to other metal ions, can be used as a basis for qualitative and quantitative detection of Hg<2+>, and is widely used for detection and in-situ online quantitative analysis of mercury ions.

The invention relates to a compound with aggregation-induced emission property as well as a preparation method and application thereof, the compound has a molecular structural formula, and R1 and R2 are respectively and independently selected from one of H and a group shown as the specification. The compound with the aggregation-induced emission property, provided by the invention, has relatively long absorption and emission wavelengths, the emission wavelength can reach a near-infrared light region, and the compound has efficient I-type ROS generation efficiency. The compound with the aggregation-induced emission property, provided by the invention, can be used for targeting tumor cell nucleus imaging after being wrapped by a cell nucleus targeting carrier to form nanoparticles. Therefore, the material can be used for tumor cell nucleus targeted photodynamic therapy.

The invention belongs to the field of chemical analysis of forensic science microphysical evidence, and particularly relates to a fluorescence probe capable of visually inspecting firearms residues and a preparation method and application of the fluorescence probe. The molecular structure of the fluorescence probe is as shown in formula I or formula II, and is used as application of visual inspection of the firearms residues. By the probe, the firearms residues are detected by colorimetric and ratio methods. The fluorescence probe capable of visually inspecting firearms residues has the advantages of good selectivity, high sensitivity, small use amount of samples, obvious visual imaging and the like, and the application prospect is wide.

The invention relates to a fluorescent probe of recognizing H2S based on 4-styrene pyridinium long wave emission and a synthetic method and application thereof. The fluorescent probe has a structuralformula as follows: a formula is as shown in the description. The preparation method comprises the following steps: inputting 4-(diethylamino) salicylaldehyde, 4-methyl pyridinium and piperidine by taking ethanol as a solvent; heating the mixture for a reflux reaction; spinning out a solvent; purifying a coarse product by means of silica gel column chromatography; carrying out separation by methane and dichloromethane as an eluent to obtain a compound 1; inputting compounds 1,2,4-dinitrofluorobenzene and potassium carbonate by taking DMF as a solvent; stirring the mixture at room temperature;filtering the mixture to obtain a coarse product; purifying the coarse product by means of silica gel column chromatography; and carrying out separation through an eluent to obtain the fluorescent probe L. The fluorescent probe has the advantages that the fluorescent probe is simple in synthetic step and easy to separate and purify; the fluorescent probe can recognize H2S in a water medium in an enhanced manner by long wave emission of fluorescence, has good selectivity, relatively high sensitivity and relatively good interference resistance and can be applied to an actual water sample to detect H2S.

The invention belongs to the field of small organic molecule fluorescent probes, and particularly relates to a coumarin-based fluorescent probe as well as a preparation method and application thereof.Aiming at the condition that the existing fluorescent probes with long emission wavelength and high light quantum yield are fewer, the invention synthesizes the fluorescent probe PQA capable of beingused for detecting the polarity in the microenvironment through a series of reactions on the basis of 7-diethylamino coumarin. The fluorescence probe has large Stokes displacement in solvents with different polarities and non-polar solvents, good solubility, a larger emission wavelength area and high light quantum yield, fluorescence quenching caused by dye self-absorption and molecular aggregation can be avoided, and interference of autofluorescence of cells or tissues can be reduced.

The invention discloses a compound I, a preparation method thereof and application of the compound I as a fluorescent probe. The compound I has near-infrared excitation/emission, the excitation wavelength ranges from 500 nm to 750 nm; and the compound is excited at a maximum absorption wavelength of 670 nm, and the emission wavelength is 700 to 810 nm. In addition, the compound I has an ultra-highsensitivity response to the PGP-1 enzyme. The detection limit for the PGP-1 enzyme at lambda ex/em=670/700 nm is 0.18 ng/mL. The compound I is used as a fluorescent probe to realize PGP-1 in vivo detection and fluorescence imaging for the first time. In vitro, cell and in vivo PGP-1 detection and fluorescence imaging can be realized, and all cells and tissues with inflammatory response and canceration can be assayed and imaged.

The invention discloses a method of preparing CdTeS quantum dots at a certain temperature with the raw materials of cadmium oxide or cadmium acetate or other inorganic substances which avoid the complication of preparing core-shell quantum dots and the shortcomings that organic cadmium like Cd(CH3)2 is inflammable and explosive and is expensive. The method is easy for operation and reproducing, safe in application and low in cost. The CdTeS quantum dots are provided with high fluorescent intensity, narrow half peak breadth, high quantum yield, good stability and a longer emission wavelength(infrared and near-infrared, Gama is equal to 620-728nm).

The invention relates to the technical field of luminescent materials, in particular to germinate yellow fluorescent powder. The germinate yellow fluorescent powder has a chemical formula as follows: Zn2-xGeO4-ySy:xMn<2+>, wherein x is 0.001 to 0.1, and y is 0.1 to 1.99. The fluorescent powder does not contain a rare-earth element with higher price and has wide excitation bandwidth; and an excitation band of the fluorescent powder covers ultraviolet light and purple light areas, and the germinate yellow fluorescent powder can be used as the yellow fluorescent powder for an ultraviolet LED (light-emitting diode).