137results about "Coumarine dyes" patented technology

The present invention includes methods for forming an object in a volume including a photohardenable composition described herein that includes a photohardenable resin component and a photoswitchable photoinitiator comprising a P-type photochromic molecule. The present invention also includes photoswitchable photoinitiators comprising a P-type photochromic molecule, preferably comprising a P-type diarylethene molecule, and photohardenable compositions and methods including such photoswitchable photoinitiators.

Photoswitchable photoinitiators comprising a photochromic molecule including one or more substituents at least one of which comprises a substituted or unsubstituted alpha-diketone moiety represented by general formula Ar1—C(═O)—C(═O)—Ar2, wherein Ar1 and Ar2 are the same or different and are independently a substituted or unsubstituted aryl group or a substituted or unsubstituted heteroaryl group. Preferably the photochromic molecule comprises a benzospiropyran molecule, a naphthopyran molecule, or a spironaphthoxazine molecule. Photohardenable compositions, hardenable resin compositions, and methods for forming an object, which photohardenable compositions, hardenable resin compositions, and methods include a photoswitchable photoinitiator described herein, are also disclosed.

The invention provides an aza [3.2. 1] bridged ring substituted fluorescent dye as well as a preparation method and application of the aza [3.2. 1] bridged ring substituted fluorescent dye. According to the fluorescent dye, an aza [3.2. 1] bridge ring is adopted as a substituent group of the fluorescent dye, so that the brightness and the light stability of the fluorescent dye are remarkably improved, the light blue shift phenomenon generated after the dye is illuminated for a long time is thoroughly avoided, meanwhile, the water solubility of the fluorescent dye can be effectively improved, and good cell membrane permeability of the fluorescent dye can be kept. The invention also provides an embodiment of the functionalized derivative of the dye for single-molecule imaging, confocal imaging and super-resolution imaging in a biological sample.

Embodiments of the present disclosure relate to cyclooctatetraene containing dyes and their uses as fluorescent labels. Also provided are composition containing cyclooctatetraene. The dyes and compositions may be used in various biological applications, such as nucleic acid sequencing.

The present invention includes methods for forming an object in a volume including a photohardenable composition described herein that includes a photohardenable resin component and a photoswitchable photoinitiator comprising a P-type photochromic molecule. The present invention also includes photoswitchable photoinitiators comprising a P-type photochromic molecule, preferably comprising a P-type diarylethene molecule, and photohardenable compositions and methods including such photoswitchable photoinitiators.

A photochromic compound according to the present invention is characterized by comprising at least two monovalent photochromic basic structural groups PC that include a T-type photochromic site, wherein the photochromic base structural groups are bonded to an organic group having a non-SO aromatic ring that does not include a sulfur atom or an oxygen atom.

The present invention aims to provide a fluorescent reagent capable of highly sensitive imaging of a lipid droplet at a level ranging from cultured cells to individuals. A lipid droplet detection reagent including a compound represented by the following General Formula (I) is provided.In the formula, m represents an integer of 0 to 5; n represents an integer of 0 to 5; X is selected from the group consisting of a sulfur atom, an oxygen atom, and a group represented by NR; R is a hydrogen atom or a group represented by —(CH2)yCH3; and y represents an integer of 0 to 5.

Provided is a photosensitive composition containing a colorant, a polymerizable compound, and a photopolymerization initiator, the content of the colorant in the total solid content of the photosensitive composition being 40 mass% or more, the polymerizable compound containing a polymerizable compound B1 having a weight-average molecular weight of 3000 or more, and the photopolymerization initiator containing a polymerizable compound B2 having a weight-average molecular weight of 3000 or more. The content of the polymerizable compound B1 in the total mass of the polymerizable compounds is 50 mass% or more, and the photopolymerization initiator contains a compound represented by formula (1). The invention also provides a film using the photosensitive composition, an optical filter, a solid-state imaging element, and an image display device. # imgabs0 #

Embodiments of the present disclosure relate to multi-dye labeled polyphosphodiester scaffolds, as well as methods and kits for sequencing by synthesis utilizing such multi-dye labeled, scaffolds as post-incorporation labeling reagents.

Nucleic acid polymers for data storage and related methods are provided. In some embodiments, the nucleic acid polymers are writable for data, and in other embodiments, the nucleic acid polymers are encoded with data when synthesized. Generally, a writable polymer may contain one or more convertible residues (e.g., chemically alterable group) bits that are enabled to provide a data code. Various methods can be utilized to generate a writable nucleic acid polymer, or a data encoded nucleic acid polymer. Various methods can be utilized to encode a nucleic acid polymer by selectively modifying convertible residues via a light or redox source with an enzyme (e.g., polymerase) conjugated to a sensitizer. Various methods of reading an encoded nucleic acid polymer are also described herein.

The purpose of the present invention is to provide: a photochromic compound that has excellent temperature dependence, decoloration speed, and durability; a naphthol derivative that can be an intermediate of the photochromic compound; a naphthol derivative that can be an intermediate of the photochromic compound; a curable composition that contains the photochromic compound; an optical article; a lens; and eyeglasses. An embodiment of the present invention provides a photochromic compound having a skeleton represented by formula (1). In formula (1), M is C, Si, or Ge. R1 is a group represented by formula (2). R2 is an alkyl group that may contain a halogen atom in a substituent, or a group represented by formula (2).

The present invention includes a method for forming an object within a volume containing a photocurable composition described herein, the photocurable composition including a photocurable resin component and a photoswitchable photoinitiator including a P-type photochromic molecule. The present invention also includes a photoswitchable photoinitiator including a P-type photochromic molecule, preferably including a P-type diarylethene molecule, and a photocurable composition and method including such a photoswitchable photoinitiator.

The invention relates to the technical field of fluorescent dye preparation, in particular to an organic fluorescent dye and a preparation method thereof.The preparation method comprises the following steps that m-diethylaminophenol and Meldrum's acid are catalyzed in an ethanol-water solvent through a supported catalyst and stirred to react in an oil bath, and an intermediate is obtained through acidification crystallization after cooling; and heating the intermediate, anhydrous potassium carbonate and ethyl iodoacetate in N, N-dimethylformamide under the protection of nitrogen to carry out alkylation reaction, and carrying out recrystallization, saponification hydrolysis and purification on the reaction liquid to obtain the organic fluorescent dye coumarin 343. The supported catalyst prepared by the invention shows good catalytic performance, stability and recoverability in the preparation reaction of the organic fluorescent dye.

The invention discloses a color generation substance, a preparation method and application of the color generation substance in color mixing of tea beverages and food, and the preparation method comprises the following steps: S1, mixing according to a proportion to prepare a phosphate buffer solution with a certain pH value; s2, weighing catechin substances, dissolving the catechin substances in the phosphate buffer solution obtained in the step S1, and fully dissolving the catechin substances to prepare a catechin buffer solution system; s3, heating the buffer system in the step S2 at high temperature to promote chemical reaction in the system; and S4, rapidly cooling by using an ice-water bath after heating is finished, and adding a protective solution to stop the reaction, so as to obtain a colored system containing the coloring substance. On the basis of an in-vitro simulation system, low-molecular-weight color generation substances are found, an efficient preparation method is established, the influence rule of concentration change on color generation is studied, the antioxidant capacity of the color generation substances is proved, and a material and theoretical basis is provided for quality regulation and control of tea and development and utilization of natural pigment substances; the color generation substance can be applied to color mixing of tea beverages and food.

The present invention relates to spiropyrans and process for the manufacture of them. In particular, a method is provided to exchange the indole and salicylaldehyde part of a spiropyran in a reversible reaction. The method is used for the synthesis of dual color photoinitiators with specific substituents and substitution patterns, which result in improved dual color volumetric printing (xolography). Furthermore, a process for locally polymerizing a starting material by dual color photopolymerization is disclosed.

Invisible fluorescent solvent inkjet ink compositions comprising a fluorescent colorant comprising a coumarin, a solvent, a binder resin, and a conductive agent are described.

The purpose of the present invention is to provide: a photochromic compound having an excellent color fading rate and excellent durability; a naphthol derivative that can become an intermediate for the photochromic compound; and a curable composition, an optical article, a lens and eyeglasses each containing the photochromic compound. According to embodiments, a photochromic compound having a backbone represented by formula (1) is provided. In formula (1), M represents C, Si or Ge; R1 represents a haloalkyl group having 1 to 20 carbon atoms inclusive; R2 represents a substituted or unsubstituted alkyl group having 1 to 20 carbon atoms inclusive or a substituted or unsubstituted haloalkyl group having 1 to 20 carbon atoms inclusive.

The present disclosure provides an aza[3.2.1]bridged ring substituted fluorescent dye and a preparation method and use thereof. According to the fluorescent dye, by adopting an aza[3.2.1]bridged ring as a substituent of the fluorescent dye, not only are the brightness and photostability of the fluorescent dye obviously improved, but also the phenomenon of spectral blue shift caused by irradiation of the dye for a long time is completely avoided. Meanwhile, the water solubility of the fluorescent dye can be effectively improved, and good membrane permeability of the fluorescent dye is maintained. The present disclosure further provides embodiments of functionalized derivatives of the dye in single molecule imaging, confocal imaging and super-resolution imaging of biological samples.

The present application relates to substituted coumarin derivatives and their uses as fluorescent labels. These compounds may be used as fluorescent labels for nucleotides in nucleic acid sequencing applications.

The present invention relates to dynamic covalent chemistry of spiropyrans and application thereof. In particular, a process is provided to synthesize spiropyrans via an exchange reaction. Thereby, substitution patterns at spiropyrans may be firstly synthetically accessible. The provided spiropyrans contain specific substituents and substitution patterns and are used as dual color photoinitiators, which result in improved dual color volumetric printing (xolography). The present invention relates further to a process for locally polymerizing a starting material by dual color photopolymerization. In particular, photoinitiators are provided, which cause efficient curing of photopolymerizable formulations upon irradiation with two different wavelengths, and which may be used for volumetric printing (xolocure initiators).

The present invention concerns bichromophoric compounds and methods of preparation thereof. Said invention also concerns the uses of these compounds, notably in the study of metallo-biomedical agents, notably metallo-pharmaceuticals or metallo-contrast agents, in particular for the study of the biotransformations of metallo-biomedical agents, notably metallo-pharmaceuticals or metallo-contrast agents, more particularly to localize and / or quantify in vitro or in vivo the biotransformations of metallo-biomedical agents, notably metallo-pharmaceuticals or metallo-contrast agents.

Provided in the present application are a kind of aza[3.2.1] bridged ring substituted fluorescent dye, and a preparation method therefor and the use thereof. In this kind of fluorescent dye, the aza [3.2.1] bridged ring is used as the substituent of the fluorescent dye, which significantly improves the brightness and light stability of the fluorescent dye, completely avoids a blue shift of light of the dye after long-term illumination, and can also effectively improve the water solubility of the fluorescent dye and maintains good cell membrane permeability thereof. Also provided in the present application are embodiments of functionalized derivatives of this kind of dye for single-molecule imaging, confocal imaging and super-resolution imaging in biological samples.

A photoconvertible photoinitiator comprising a photochromic molecule comprising one or more substituents wherein at least one substituent comprises a substituted or unsubstituted alpha-diketone moiety represented by the general formula Ar1-C (= O)-C (= O)-Ar2 wherein Ar1 and Ar2 are the same or different and are independently a substituted or unsubstituted aryl group or a substituted or unsubstituted heteroaryl group. Preferably, the photochromic molecule comprises a benzo spiropyran molecule, a naphthopyran molecule, or a spironaphthoxazine molecule. Also disclosed are photocurable compositions, curable resin compositions, and methods of forming an object, wherein the photocurable compositions, curable resin compositions, and methods include the photoconvertible photoinitiators described herein.

The present application relates to tertiary amine substituted coumarin derivatives and their uses as fluorescent labels. These compounds may be used as fluorescent labels for nucleotides in nucleic acid sequencing applications.

The present invention includes a method for forming an object within a volume containing a photocurable composition described herein, the photocurable composition including a photocurable resin component and a photoswitchable photoinitiator including a P-type photochromic molecule. The present invention also includes a photoswitchable photoinitiator including a P-type photochromic molecule, preferably including a P-type diarylethene molecule, and a photocurable composition and method including such a photoswitchable photoinitiator.