6results about How to "High molar extinction coefficient" patented technology

The invention relates to a preparation method of a tetrahydroxy tetraphenyl ethylene photoinitiator. According to the method, tetrahydroxy tetraphenyl ethylene and a diazo naphthoquinone sulfonyl chloride compound are subjected to a condensation reaction to prepare the diazo naphthoquinone photoinitiator, and the photolysis rate of the diazo naphthoquinone photoinitiator is tested. The preparation method specifically comprises the following steps: in an organic solvent, taking tetrahydroxy tetraphenyl ethylene and diazonaphthoquinone sulfonyl chloride as raw materials, and carrying out esterification condensation reaction under the action of a catalyst to obtain the tetrahydroxy tetraphenyl ethylene photoinitiator. The tetrahydroxy tetraphenyl ethylene photoinitiator synthesized by the invention has the following advantages: compared with the traditional photoinitiator, the light sensitivity is obviously improved; the ultraviolet absorption capability is stronger, and the photosensitive performance is more excellent.

The invention relates to the field of organic light-emitting materials, and discloses a color conversion composition, a blue light-driven LED and a preparation method thereof, organic boron heteropolycyclic aromatic hydrocarbon organic light-emitting materials (BODIPY and BN) in the color conversion composition are utilized, the molar extinction coefficient is large, the emission spectrum half-peak width is very narrow (10-50 nm), the quantum yield is high, and the thermal stability and chemical stability are good. Compared with the prior art, the color conversion film provided by the invention has the characteristics of simple structure and diverse structure, can realize complete coverage from the whole visible light area to the near-infrared light area, and has excellent compatibility with a base material (such as binder resin), so that the color conversion film with excellent performance is formed, and green light and red light with high luminous efficiency and high color purity can be obtained when the color conversion film is applied to an LED driven by blue light, so that the color rendering index of the LED is improved.

The invention belongs to the technical field of organic synthesis, and particularly discloses a BODIPY photodynamic antibacterial fluorescent probe with an aromatic structure and a preparation method thereof.The BODIPY photodynamic antibacterial fluorescent probe is characterized in that a BODIPY fluorescent dye and an aldehyde compound are subjected to a novenger condensation reaction, and aryl is introduced to the meso position of BODIPY, so that the two-photon absorption capacity and chemical stability of the compound are enhanced; the introduction of aromatic rings and iodine atoms to a certain extent can have a very good inhibition effect on the proliferation of bacteria, so that not only is the antibacterial effect provided, but also the wound healing can be promoted. Comparison experiments find that the antibacterial effect of the BODIPY with the optimized structure is obviously enhanced, and the BODIPY with non-iodinated aromatic rings introduced to the meso site shows the strongest antibacterial effect. The invention not only provides a design strategy for the development of novel near-infrared photosensitizers, but also has great application potential and research significance in the aspect of photodynamic diagnosis and treatment.

The application belongs to the technical field of biological detection, and aims at solving the single color change mode and poor sensitivity of the current ELISA kit, and provides CMO nano-oxidase, a CMO-OVA-MC-LR probe, a kit, a preparation method and application thereof.The CMO nano-oxidase is a raspberry-shaped Co-doped Mn3O4 oxidase, the nano-oxidase is a two-heterojunction CMO of Co3O4 and Mn3O4 synthesized by one-pot hydrothermal method, and the particle size is 110-140 nm.The detection limit of the enzyme-linked immunosorbent kit constructed by the application for microcystin LR (MC-LR) is 0.505 ng / mL, and the quantitative range is 0.195-100 ng / mL.Benefiting from the strong catalytic activity and good biocompatibility of the nano-enzyme, the label and signal response mode open up a new way for the sensitivity improvement of the immunosensor determination, and are conducive to further expanding the application of the immunosensor.

The invention relates to preparation and application of tetracoumarin-based beta-beta coupled double-BODIPY near-infrared photothermal dye, which are realized by the following method: carrying out C-C coupling reaction on a BODIPY monomer derivative (I) and anhydrous ferric trichloride to obtain a beta-beta coupled double-BODIPY derivative (II), and carrying out reaction on the beta-beta coupled double-BODIPY derivative (II) and 7-(N, N-dimethyl formamide)-1, 2, 3, 4-tetracoumarin-based beta-beta coupled double-BODIPY derivative (II) to obtain the tetracoumarin-based beta-beta coupled double-BODIPY near-infrared photothermal dye. The preparation method comprises the following steps: carrying out Knoevenagel condensation reaction on N, N '-diethylamino) coumarin-3-formaldehyde to obtain the near-infrared photothermal agent tetracoumarin-based beta-beta coupled double BODIPY derivative (III). The preparation method has the advantages of simple reaction steps, mild reaction conditions, good selectivity and wide application range. The photothermal agent has relatively strong near-infrared absorption, excellent photothermal conversion efficiency and cell apoptosis ability, can be used as a novel photothermal therapy anti-tumor and antibacterial drug, and has important scientific significance and application value.

This invention relates to a pyrrolopyrrole organic small molecule photothermal material with high photothermal conversion efficiency, its preparation method, and its application. The invention belongs to the field of organic small molecule photothermal materials. It aims to solve the problems of poor thermal stability and low photothermal conversion efficiency in existing photothermal materials. Preparation method: BrDPPBr, R-boronate, potassium carbonate, and a high-boiling-point solvent are mixed, then heated, and a phosphine compound is added. The mixture is heated and stirred continuously. After the reaction, it is cooled to room temperature, and then pure water is added to precipitate the solid. The solid is then recrystallized and purified to obtain the pyrrolopyrrole organic small molecule photothermal material. Application: It is used for water evaporation. This invention relates to pyrrolopyrrole organic small molecule photothermal materials with high photothermal conversion efficiency, their preparation, and their applications.