66results about "Styryl dyes" patented technology

The invention discloses a triarylmethane type I photosensitive dye as well as a synthesis method and application thereof. The structure of the dye is shown as a general formula I; intramolecular charge separation is optimized by regulating substituent groups, and the generation efficiency of superoxide anions and hydroxyl radicals is remarkably improved. According to the synthesis method, 4-diphenylaminobenzaldehyde or 4-vinyl benzaldehyde is used as a raw material, efficient preparation is achieved through the steps of condensation, oxidation and the like, the raw material is easy to obtain, and operation is easy and convenient. The dye has strong absorption at the wavelength of 600-630 nm, is suitable for red light triggered photodynamic therapy (PDT), especially keeps high reactive oxygen yield under the hypoxic condition, and breaks through the oxygen dependence limitation of traditional PDT. Experiments show that the dye can induce ferroptosis of tumor cells, has the functions of fluorescence imaging and treatment, and has wide application prospects in the fields of antitumor drugs, in-vivo fluorescence labeling, photoresponsive functional preparations and the like.

The invention discloses a preparation method and application of near-infrared fluorescent dye DOM-O for acute alcoholic liver injury detection. The specific chemical structural formula of the near-infrared fluorescent dye DOM-O is shown in the specification. The near-infrared fluorescent dye prepared by the invention has excellent fluorescence imaging performance, can realize specific fluorescence imaging diagnosis of the acute alcoholic liver injury, and provides an imaging dye with application prospect for early detection and clinical diagnosis of the acute alcoholic liver injury.

The present application relates to an optical filter having a substrate and a dielectric multilayer film laminated on at least one main surface side of the substrate and serving as an outermost layer, wherein the substrate has a resin film containing a pigment (U) having a maximum absorption wavelength in the range of 360 nm to 395 nm in dichloromethane, a pigment (A) having a maximum absorption wavelength in the range of 600 nm to 800 nm in dichloromethane, and a resin, and the optical filter satisfies specific spectral characteristics.

The application discloses a kind of two-photon fluorescent probe for detecting industrial hydrogen sulfide or sodium sulfide and a preparation method thereof, and relates to the technical field of fluorescent probe.The application designs and synthesizes a compound with D-Π-A structure, which can be used as a two-photon fluorescent probe to selectively detect H2S, and is suitable for detecting H2S or Na2S residue in industry, with high sensitivity and good specificity.The reaction product of the compound and H2S can be used as an organic fluorescent dye.

Design and applications of a class of water-soluble small molecules represented by formula 1. The molecules, in their dilute aqueous solutions, exhibit lower critical solution temperature (LCST) phase transitions near room temperature, inducing a temperature triggered switching of opacity. Further, disclosed is a scalable smart window, akin to a radiative energy management system, that can be incorporated into the built environment for imparting energy efficiency. The window fabrication is facile wherein the aqueous solution is sandwiched between two transparent glass panes to enable modulation of light and heat transmission. The dynamic window of present invention represents with multifarious applications in developing scalable, smart energy management systems for indoor building environments is envisioned to be a major contribution towards cost effective smart glass technologies.

To provide 3D-printed products.SOLUTION: The present invention relates to urethane-acrylate-resin-based 3D-printed products having a colour distance ΔE of less than 20 from the L*a*b* coordinates for a colour number, beginning with "3", of the RAL colour chart, comprising at least one red perinone dye to be selected from 8,9,10,11-tetrachloro-12H-phthaloperin-12-one and / or 14H-benz[4,5]isoquino[2,1-a]perimidin-14-one dissolved therein, to the use of the red perinone dyes for producing 3D-printed products having a colour distance ΔE of less than 20 from the L*a*b* coordinates for a colour number, beginning with "3", of the RAL colour chart by photopolymerization, and to a method for increasing the lightfastness and the colouristic properties of photopolymerizable urethane-acrylate-resin-based compositions and 3D-printed products based thereon by means of at least one red perinone dye to be selected from 8,9,10,11-tetrachloro-12H-phthaloperin-12-one and / or 14H-benz[4,5]isoquino[2,1-a]perimidin-14-one dissolved therein.SELECTED DRAWING: None

The present invention relates to compounds of Formula (I) and their use in the detection and monitoring of autophagic activity, as well as their use in the identification, treatment, prevention, or amelioration of diseases associated with dysregulation of autophagy.

The invention discloses an electron-rich BODIPY type I photosensitive dye as well as a preparation method and application thereof. The photosensitive dye has a structure as shown in a general formula I. The BODIPY photosensitive dye compound with the I-type photodynamic performance disclosed by the invention has relatively strong near-infrared region absorption and electron transfer capabilities, and superoxide anions can be efficiently generated. Under the excitation of near-infrared light, the photodynamic killing can be carried out on normal oxygen and hypoxic cancer cells. Meanwhile, the electron-rich type BODIPY type I photosensitive dye has a good application prospect in the aspect of treating solid tumors in a living body.

To provide 3D-printed products.SOLUTION: The present invention relates to urethane-acrylate-resin-based 3D-printed products having a colour distance ΔE of less than 20 from the L*a*b* coordinates for a colour number beginning with "2" of the RAL colour chart, comprising at least one orange methine dye dissolved therein, to the use of orange methine dyes for producing 3D-printed products having a colour distance ΔE of less than 20 from the L*a*b* coordinates for a colour number of the RAL colour chart beginning with "2" by photopolymerization-based 3D printing, and to a method for increasing the lightfastness and colouristic properties of photopolymerizable urethane-acrylate-resin-based compositions and 3D-printed products to be produced therefrom having a colour distance ΔE of less than 20 from the L*a*b* coordinates for a colour number beginning with "2" of the RAL colour chart by means of at least one orange methine dye dissolved therein.SELECTED DRAWING: None

A fluorescent dye, as well as a preparation method and uses thereof, wherein the fluorescent dye is sensitive and specific to viscosity and has low background fluorescence; it can also be used as a fluorescent activated and lighted probe used for fluorescent labeling, quantification or monitoring of protein, enzymes or nucleic acid.

To provide an oil droplet staining agent and an inner mitochondrial membrane staining agent which can estimate the composition of oil droplets and the membrane structure (membrane composition) of the inner mitochondrial membrane.SOLUTION: A bisphosphoryl-crosslinked stilbene compound is represented by general formula (1) [where Ar1 and Ar2 are the same or different to represent a substituted or unsubstituted aromatic hydrocarbon ring or a substituted or unsubstituted heteroaromatic ring. R1 and R2 are the same or different to represent a hydrogen atom, a substituted or unsubstituted alkyl group, a substituted or unsubstituted cycloalkyl group, or a substituted or unsubstituted (hetero)aryl group. Y1 and Y2 are the same or different to represent a phosphine oxide group or the like].SELECTED DRAWING: None

The present application relates to a dye compound of the formula (I), or a salt thereof. The present application relates to the use of the fluorescent dye or salt for various applications, such as for staining cells and for assessing the effect of an agent on a cell phenotypic state.

To provide an optical filter in which high transmittance of visible light, particularly transmittance of blue light, is favorably maintained, and also in which decrease in near-infrared light shielding performance at high incident angles, such as light leakage, is suppressed.SOLUTION: The present invention relates to an optical filter including a base material and a dielectric multilayer film laminated on at least one main surface of the base material. The base material includes a pigment (A) as a near-infrared absorption pigment and a resin film including resin. The pigment (A) includes at least one of the compound shown by the following formula (A1) and the compound shown by the following formula (A2). The optical filter satisfies a specific spectral characteristic.SELECTED DRAWING: Figure 1

The present invention relates to the field of optical imaging. More specifically, the present invention relates to compounds of the cyanine family with near-infrared emission and their conjugates with biological ligands, characterized by improved physicochemical and biological properties. The present invention also relates to the use of these compounds as optical diagnostic agents in the imaging or therapy of solid tumors, their preparation methods, and compositions containing them. The compound has formula (I), where X is a direct bond or -O-; Y is a group selected from linear or branched C-C alkyl, C-C cycloalkyl, and heterocyclyl substituted by at least two hydroxyl groups; R and R are each independently linear or branched C-C alkyl substituted by a group selected from -SOH, -COOH, -CONH, and -COO-C-C alkyl; and R is hydrogen, -SOH, or linear or branched C-C alkyl substituted by -COOH or -CONH-Y, where Y is a group selected from linear or branched C-C alkyl, C-C cycloalkyl, and heterocyclyl substituted by at least two hydroxyl groups. JPEG2023530575000042.jpg72166

To provide a novel fluorescent dye and kit for readily detecting a compound and a composition or a cell capable of suitably using in a fluorescent dye etc. as well as, a new method for readily detecting a cell etc., and etc.SOLUTION: By applying a fluorescent dye containing a compound and a composition that can be used for a red fluorescent dye based on a specific pyrene structure to stain a cell, a tissue, or an organ, a detection method capable of readily detecting a cell, a tissue, or an organ is provided.SELECTED DRAWING: None

The invention discloses a flavonoid fluorescent dye, a supramolecular fluorescent probe, a preparation method of the supramolecular fluorescent probe and a pyriproxyfen detection method. The probe is constructed by spontaneously assembling the albumin derivative and the flavonoid fluorescent dye in a buffer solution. The detection mechanism is shown as follows: the flavonoid dye presents characteristic red fluorescence in a free state, and obvious fluorescence blue shift is triggered after the flavonoid dye is combined with albumin. When pyriproxyfen is introduced into the system, hydrophobic molecules enter an albumin hydrophobic cavity in a competitive binding manner, so that dye molecules have a replacement effect. In the process, along with the bidirectional response of a fluorescence signal, namely, the yellow fluorescence intensity and the pyriproxyfen concentration are in negative correlation, and the reconstructed dye aggregation state triggers the enhancement of a green fluorescence channel signal, so that the quantitative conversion of the fluorescence chroma of the solution from yellow to green is finally realized. Based on the ratio-type fluorescence signal, the probe system has an obvious colorimetric effect when being used for detecting pyriproxyfen in environment, food and the like, and the color change can be directly observed by naked eyes.

The invention belongs to the technical field of organic compounds and artificial boards, and relates to a whitening agent, a preparation method thereof and application of the whitening agent in whitening type medium density fiberboards, the whitening agent comprises the following components by mass percent: 2-5% of hydrogen peroxide, 0.2-0.6% of sodium silicate, 0.5-1.5% of sodium hydroxide, 0.1-0.4% of water-soluble stilbene fluorescent whitening agent and the balance of water. The preparation method comprises the following steps: sequentially adding the components into water at 60-65 DEG C, stirring and dissolving, and keeping the temperature at 60 DEG C for later use. When being applied, the cleaning agent is added in a wood chip washing process, the mass of the cleaning agent is 1-1.5% of the total mass of cleaning water for the first time, and 0.05-0.08% of the cleaning agent is supplemented per hour subsequently. According to the whitening agent, through the synergistic effect of chemical oxidation and physical color complementing, the whiteness of a fiberboard reaches 31-36 (only 14 in a conventional process), the physical and chemical properties meet the GB / T 11718-2021 standard, and the whitening agent is environmentally friendly, free of residues, simple to prepare and apply, suitable for industrial continuous production and capable of remarkably improving the added value of products.

The present invention provides a laser welding ink application tool that allows for the relatively thin, uniform, and easy application of laser welding ink to desired locations. [Solution] A laser welding ink coating tool 1 comprising an ink 5 containing a near-infrared absorbing dye and a solvent, a container 2 containing the ink 5, and a core material 3 from which the ink 5 contained in the container 2 is supplied, wherein the ink 5 can be coated from the core material 3.

The present disclosure is directed, in general, to (1) nonlinear optical (NLO) chromophores containing 3-methyl-2-cyclopenten-l- one based Fl-bridge groups, including (2) compositions / materials / resistive layers comprising NLO chromophores containing 3-methyl-2- cyclopenten-l-one based ll-bridge groups, and the methods of making the compositions / materials / resistive layers comprising NLO chromophores containing 3-methyl-2-cyclopenten-l-one based H- bridge groups (e.g., methods of drying and / or poling, and the like), (3) uses of NLO chromophores containing 3-methyl-2-cyclopenten-l-one based ll-bridge groups in electro-optic devices (e.g., EOMs). The nonlinear optical (NLO) chromophores have the following formula (II), wherein X is a cyclopenten-based Π-bridge having formula Π1 or Π2.

The invention provides an isophorone dye derivative LYC-CF3 as well as a synthesis method and application thereof. The specific name of the isophorone dye derivative is (E)-4-(2-(3-(dicyanomethylene)-5, 5-dimethylcyclohex-1-ene-1-yl) vinyl)-2-(trifluoromethyl) phenyl trifluoromethanesulfonate, and the structural formula of the isophorone dye derivative is shown in the description. The invention also provides a synthesis method of the derivative LYC-CF3, and a fluorescence imaging experiment of the derivative LYC-CF3 on O2 <-> in PC-12 cells. Through verification of a fluorescence spectrum and a laser confocal microscope, the derivative LYC-CF3 has quick response to O2 <-> in an in-vitro test and cells and relatively remarkable fluorescence imaging capability. Therefore, LYC-CF3 can be used as a fluorescent probe for in-vitro detection of O2 <-> and detection of O2 <-> in cells.

The present application relates to a kind of human cysteine gamma-cleaving enzyme (hCSE) response fluorescent dye and its preparation method and application.The excitation wavelength of the fluorescent dye is 500-630nm, and the emission wavelength is 650-850nm.The dye can be selectively imaged hCSE enzyme on living cells rapidly, with high signal-to-noise ratio, compared with prior art, cell fluorescence signal enhancement can reach 10 times.In addition, the dye is the first fluorescent probe that can be used for in vivo identification and imaging of hCSE enzyme, by intratumoral injection, with small dose, tumor fluorescence signal can be significantly enhanced in a short time.The application direction includes hCSE enzyme fluorescence detection and imaging, imaging preparation, hCSE enzyme targeted tumor light-driven treatment related preparation, hCSE enzyme targeted tumor chemotherapy prodrug preparation, hCSE enzyme targeted radioimaging preparation, and as a tool for biomarker research and drug development.

The application provides a semi-florin chemotherapy drug and a synthesis method thereof, relates to the technical field of drug synthesis, and the semi-florin derivative exhibits significant selective anti-tumor activity, and the mechanism of action is that after entering tumor cells, the semi-florin derivative can induce the increase of the level of reactive oxygen species (ROS) in the cells, causes the collapse of the mitochondrial membrane potential, and finally triggers the late apoptosis pathway of the cells.

Compounds of the formula (I), polymeric photoinitiators based upon compounds of the formula (I), photopolymerizable compositions comprising compounds of the formula (I), a process for preparing compounds of the formula (I), a process for the polymerization of compounds involving irradiating compounds of the formula (I), coated substrates coated with a photopolymerizable composition comprising compounds of the formula (I), process for the photographic production of relief images in which a coated substrate coated with a photopolymerizable compositions comprising compounds of the formula (I) is subjected to imagewise exposure and then the unexposed portions are removed with a developer, a color filter comprising a photosensitive resin comprising a compound of the formula (I), and a use of a compound of the formula (I) as a photoinitiator.

The present invention discloses a large Stokes shift fluorescent dye targeting the endoplasmic reticulum, and its preparation method and application. It is a new fluorescent dye based on the classic ESIPT dye and incorporating 4-phenylpyridinium salt, specially designed for endoplasmic reticulum targeting, and has both a large Stokes shift and a high viscosity response signal-to-noise ratio. Excellent endoplasmic reticulum targeting is ensured by adjusting the lipophilic-amphiphilic balance of the dye. The Stokes shift exceeds 200nm, eliminating self-absorption interference and enhancing imaging quality. In addition, the unique electron donor-acceptor structure makes the fluorescent signal sensitive to solvent viscosity, enabling accurate reporting of changes in the endoplasmic reticulum microenvironment. Therefore, the present invention not only improves the accuracy and efficiency of endoplasmic reticulum imaging, but also provides a powerful tool for understanding endoplasmic reticulum dynamics in cell and medical research, especially in monitoring changes in endoplasmic reticulum viscosity in damaged cells, showing significant advantages.

According to the application of the fluorescent probe based on the triphenylamine derivative in fluorescent ink, fingerprint powder and fish freshness indication, the structural formula of the fluorescent probe is shown in the specification, the fluorescence of the fluorescent probe is remarkably enhanced in a solid or high-water-content environment, and the problem of aggregation fluorescence quenching of a traditional dye is effectively solved. The fluorescent probe shows broad-spectrum and high-sensitivity fluorescent response to various volatile amines, and the recognition mechanism is clear. On the basis, the invention develops a two-channel visual freshness indication label, lossless and real-time monitoring of the freshness of the fish meat is realized through synchronous change of color and fluorescence, and the evaluation result is consistent with the grade determined by a national standard method. In addition, the probe can be prepared into fluorescent ink for information encryption and high-contrast fingerprint showing powder, and microscopic characteristics of hidden fingerprints can be clearly shown under sunlight / ultraviolet light. High-sensitivity sensing, intelligent packaging and multifunctional material application are integrated, and the intelligent packaging box has important practical value in the fields of food safety and public safety.

An optical filter includes: a transparent substrate; and an absorption layer on the transparent substrate, the absorption layer containing at least one dye (X) having a maximum absorption wavelength in 600 to 1000 nm. A laminate of the transparent substrate and the absorption layer satisfies all of the following characteristics (i-2) to (i-4): (i-2) a maximum internal transmittance in 700 to 850 nm is 35% or lower; (i-3) a difference between the maximum internal transmittance and a minimum internal transmittance in 700 to 850 nm is 20% or smaller; and (i-4) OD(A) and OD(B) satisfy the following relationship: OD(A) / OD(B)<0.07 where OD(A) is an average optical density of an internal transmittance in 500 to 600 nm and OD(B) is an average optical density of an internal transmittance in 700 to 850 nm.

This invention provides a compound that exhibits excellent heat resistance and oxidation resistance, and can stably maintain its absorbance properties even when maintained under high temperature or high temperature and high humidity conditions. It also provides a resin film in which desired optical properties are ensured by applying the compound, and provides applications for the compound. [Solution] The compound is the compound shown in chemical formula 1 below. JPEG2026069446000032.jpg4455 ...chemical formula 1

The application discloses a multi-cyan structure near-infrared fluorescent dye, by changing the structure of end group and intermediate condensing agent, the accurate control of dye electron donating type, charge separation degree and electron mobility is realized. The multi-cyan structure near-infrared fluorescent dye compound prepared by the application has significant advantages in spectral characteristics, the molar extinction coefficient is higher than that of traditional multi-cyan dye, the light energy absorption capacity is strong, which is helpful to improve the light energy utilization rate and reduce the dye amount; the absolute fluorescence quantum yield reaches a high level, the imaging signal intensity and sensitivity are significantly enhanced, a more sensitive and reliable tool is provided for biological imaging and molecular detection; the fluorescent dye compound has excellent biocompatibility and phototoxicity, the safety of the dye in the application in the biological and medical fields is ensured, and strong support is provided for the application of the dye in the field of cancer treatment.

The application discloses dendritic silica spheres, a composite phase change energy storage material and a preparation method and application thereof; the preparation method of the dendritic silica spheres comprises the following steps: dispersing a block type polyurethane surfactant and a cationic surfactant in a solvent to prepare a dispersion liquid, stirring to form an emulsion after adding cyclohexane oil phase, adding tetraethoxysilane and ammonia water to react, and washing, drying and calcining the separated solid product to obtain the dendritic silica spheres. The prepared silica nanospheres and a phase change material are prepared into the dendritic silica composite phase change energy storage material through a vacuum impregnation method. The new method for synthesizing the dendritic silica spheres is simple and controllable, the particle size and pore structure of the silica spheres can be controlled, and the synthesized composite phase change energy storage material exhibits good thermal energy storage capacity and shape stability. The application has great application potential in the fields of building energy saving, electronic equipment and battery heat management.

To provide 3D-printed products.SOLUTION: The present invention relates to urethane-acrylate-resin-based 3D-printed products having a colour distance ΔE of less than 20 from the L*a*b* coordinates for a colour number, beginning with "3", of the RAL colour chart, comprising at least one red perinone dye to be selected from 8,9,10,11-tetrachloro-12H-phthaloperin-12-one and / or 14H-benz[4,5]isoquino[2,1-a]perimidin-14-one dissolved therein, to the use of the red perinone dyes for producing 3D-printed products having a colour distance ΔE of less than 20 from the L*a*b* coordinates for a colour number, beginning with "3", of the RAL colour chart by photopolymerization, and to a method for increasing the lightfastness and the colouristic properties of photopolymerizable urethane-acrylate-resin-based compositions and 3D-printed products based thereon by means of at least one red perinone dye to be selected from 8,9,10,11-tetrachloro-12H-phthaloperin-12-one and / or 14H-benz[4,5]isoquino[2,1-a]perimidin-14-one dissolved therein.SELECTED DRAWING: None