5 results about "Methine dye" patented technology

Food contact materials with a color difference ΔE <20 from the L*a*b* coordinates to a color number starting with "1" of the RAL color chart according to the color model according to EN ISO 11664-4, as determined according to DIN 5033 (1979), based on compositions containing at least one polyester or polystyrene and a colorant consisting of at least one yellow methine dye or at least one yellow quinophthalone dye and at least one ethylene oxide-propylene oxide block copolymer with a central propylene oxide unit between two ethylene oxide units, a molar mass determined from the OH number to be determined according to DIN / ISO 4629, in the range of 5500 to 7500 g / mol, a mass fraction of ethylene oxide units in the range of 45 to 55 wt.% and a flocculation point to be determined according to EN 1890 method B in the range of 70°C to 85°C.

The invention relates to inhibitors of the PKC signaling pathway for use in the treatment of septic cholestasis, wherein the inhibitors are targeted into the liver by a selective nanostructured delivery system, wherein the selective nanostructured delivery system comprises at least one polymethine dye and at least one polymer and / or at least one lipid and / or at least one virus-like particle, wherein the at least one polymethine dye is a symmetrical or asymmetrical polymethine.

The application belongs to the technical field of small molecule fluorescent probe, and provides a kind of nonamethylenecyclooctyne dye probe and its application in disease diagnosis.A kind of nonamethylenecyclooctyne dye is prepared, and the dye can be rapidly covalently combined with serum albumin in vivo or in vitro to form fluorescent protein, which is suitable for targeted imaging of various diseases.Nonamethylenecyclooctyne dye is injected through tail vein, rapidly combined with serum albumin in vivo, and can be used for targeted imaging and diagnosis of different degrees of brain damage in mouse stroke and targeted imaging of tumor.In addition, the pre-prepared nonamethylenecyclooctyne dye and human serum albumin complex can also be injected through tail vein to achieve rapid targeted imaging of tumor.Compared with ICG, NIR-940 can rapidly covalently combine with serum albumin at 37 DEG C or even room temperature, overcoming the defect of non-covalent combination of ICG, and being suitable for high-contrast targeted imaging of disease area.

The invention provides a fused aza derivative as well as preparation and application thereof. The absorption intensity of the fused aza derivative in a near-infrared region is higher, and the maximum molar absorption coefficient in a solution state exceeds 1.0 * 10 < 5 > L.M <-1 >. Cm <-1 >; the light stability and the light fastness of the dye are obviously superior to those of methine dyes, and the European wool light fastness third-level standard is met. The structure of the fused aza derivative is shown as a formula (I),

Food contact materials with a color difference ΔE <20 from the L*a*b* coordinates to a color number starting with "2" of the RAL color chart according to the color model according to EN ISO 11664-4, to be determined according to DIN 5033 (1979), based on compositions containing at least one polyester or polystyrene and a colorant consisting of at least one orange methine dye and at least one ethylene oxide-propylene oxide block copolymer with a central propylene oxide unit between two ethylene oxide units, a molar mass determined from the OH number to be determined according to DIN / ISO 4629, in the range of 5500 to 7500 g / mol, a mass fraction of ethylene oxide units in the range of 45 to 55 wt.% and a flocculation point to be determined according to EN 1890 method B in the range of 70°C to 85°C.