The invention relates to a nanometer SiO2 hybrid polyester modified organosilicon non-stick paint. The non-stick paint is prepared mainly by mixing the following components by weight: 50 to 70 parts of a nanometer SiO2 hybrid polyester modified organosilicon resin, 3 to 10 parts of an epoxy resin, 3 to 10 parts of a melamine resin, 3 to 10 parts of a filling material, 20 to 30 parts of an organic solvent, 1 to 5 parts of a non-stick auxiliary agent, 0.3 to 1 part of a polymeric dispersant and 1 to 3 parts of an adhesion promoter. A coating prepared through coating of the non-stick paint has the characteristics of good non-stick performance, good temperature tolerance, excellent chemical resistance, corrosion resistance, high hardness and the like, is especially applicable to non-stick coatings for ferrous baking equipment and a cake mould and accords with relevant FDA and LFGB standards for food contact materials. According to the invention, the technical defect of a high sintering temperature (normally, higher than 380 DEG C) of a conventional fluoro paint is overcome; and the non-stick paint provided by the invention only needs a sintering temperature of about 280 DEG C, so a phosphating film on the surface of a ferrous substrate is protected, resistance to chemical corrosion is improved, and energy saving and environmental protection are realized.