5 results about "Fluorescent nanoparticles" patented technology

The present application relates to fluorescent nanoparticles based on fluorinated zwitterionic random copolymer and its preparation method and application, the fluorescent nanoparticles include the single chain nanoparticles formed by poly trifluoroethyl methacrylate-co-methacryloyloxyethyl sulfobetaine, the molecular chain end of the poly trifluoroethyl methacrylate-co-methacryloyloxyethyl sulfobetaine is connected with ACQ type group selected from anthryl, perylene imide group and pyrene base or AIE type group selected from tetraphenyl ethylene base, carbazole base and cyanine-containing triphenyl ethylene group.The fluorescent nanoparticles based on the poly trifluoroethyl methacrylate-co-methacryloyloxyethyl sulfobetaine of the present application that terminal fluorescent group is terminated, has excellent controllable fluorescent luminescence performance.It is considered that the single chain nanoparticles have isolation effect, avoid the fluorescence quenching effect of ACQ type group, and can provide limited microenvironment for AIE type group, ensure the fluorescent luminescence performance of nanoparticles.

The present invention provides fluorescent nanoparticles with a long fluorescence lifetime and a method for producing the same. [Solution] The fluorescent silica nanoparticles of the present invention comprise silica, and rare earth fluorescent complexes and gold nanoparticles encapsulated within the silica. Furthermore, the method of the present invention for producing fluorescent silica nanoparticles includes providing gold nanoparticle-encapsulated silica nanoparticles containing gold nanoparticles, and coating the gold nanoparticle-encapsulated silica nanoparticles with silica containing a rare earth fluorescent complex.

The application discloses a preparation method of polymer fluorescent nanoparticles. First, a polylactic acid-polyurethane-polyacrylic acid copolymer is synthesized by reacting alcoholysis-recovered double-hydroxyl polylactic acid, 4,4'-diphenyl methane diisocyanate, polycaprolactone polyol, hydroxyethyl acrylate and acrylic acid; second, a polyethylene imine aqueous solution is prepared, and the polyethylene imine aqueous solution is added dropwise into a butyl acetate solution of the polylactic acid-polyurethane-polyacrylic acid copolymer, high-speed stirring is conducted, and a water-in-oil emulsion is formed; finally, the water-in-oil emulsion is heated, water is evaporated, a fluorescent solution is formed, and the fluorescent solution is subjected to spray drying to obtain the fluorescent nanoparticles. The nanoparticles of the paper cup are uniform in size, have excellent fluorescent performance and biocompatibility, and have a wide application prospect.