Magnetic nanoparticle therapies

a technology of magnetic nanoparticles and nanoparticles, applied in the field of fluorescent nanoparticles, can solve the problems of many anatomical spaces and tissues, inaccessible and viewable, and expensive and time-consuming imaging equipment use,
US20080255403A1Inactive Publication Date: 2008-10-16ETHICON ENDO SURGERY INC
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Patent Information

Authority / Receiving Office
US · United States
Patent Type
Applications(United States)
Current Assignee / Owner
ETHICON ENDO SURGERY INC
Publication Date
2008-10-16
Estimated Expiration
Not applicable · inactive patent

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Abstract

Various compositions, methods, and devices are provided that use fluorescent nanoparticles, which can function as markers, indicators, and light sources. The fluorescent nanoparticles can be formed from a fluorophore core surrounded by a biocompatible shell, such as a silica shell. In one embodiment, the fluorescent nanoparticles can be delivered to tissue to mark the tissue, enable identification and location of the tissue, and / or illuminate an area surrounding the tissue. In another embodiment, the fluorescent nanoparticles can be used on a device or implant to locate the device or implant in the body, indicate an orientation of the device or implant, and / or illuminate an area surrounding the device or implant. The fluorescent nanoparticles can also be used to provide a therapeutic effect.
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Description

CROSS REFERENCE TO RELATED APPLICATIONS

[0001] This application claims priority to U.S. Provisional Patent Application No. 60 / 911,546 filed on Apr. 13, 2007 and entitled “Fluorescent Nanoparticle Compositions, Methods, and Devices,” which is hereby incorporated by reference in its entirety.FIELD OF THE INVENTION

[0002] The present invention relates to fluorescent nanoparticles, and in particular to various compositions, methods, and devices that use fluorescent nanoparticles.BACKGROUND OF THE INVENTION

[0003] Illuminating light incident on tissue is transmitted through, scattered by, absorbed, or reflected by that tissue. At certain wavelengths, after absorbing the illuminating light, tissue can re-emit light energy at a different wavelength (autofluorescence). If a substance is introduced into the tissue or is present between tissue layers, or in lumens, it can fluoresce after absorbing incident light as well. Detecting devices can be placed in relationship to the tissue to image light t...

Claims

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