111 results about "Color flow" patented technology

A system and method for improved imaging is disclosed. An exemplary system provides a peripheral ultrasound system connected to a host computer with a plug-and-play interface such as a USB. An exemplary system utilizes a dedicated graphics processing unit such as a graphics card to analyze data obtained from a region of interest to produce an image on one or more output units for the user's viewing. Based on the image displayed on the output units, the user can determine the velocity of the moving tissue and fluid. The system of the present invention can be used to produce a Doppler color flow map or for power Doppler imaging.

A medical ultrasound viewing system for processing a sequence of three-dimensional (3-D) ultrasound images far performing a quantitative estimation of a flow through a body organ comprising means for performing steps of acquiring a sequence of 3D color flow images, of said flow; assessing the flow velocity values in the 3D images, constructing isovelocity surfaces (6) by segmentation of the flow velocity values; computing the volume (Vol) delimited by the isovelocity surfaces; and using the flow velocity value (V) and the volume (Vol) computed from a segmented surface for computing the surface of an orifice (3) of the organ through which the flow propagates. The viewing system further comprises means for performing steps of measuring the peak velocity (VREG) of said flow through said orifice; computing the surface of the orifice (SOR) through which the flow propagates as a function of the flow velocity value (V) at an isovelocity surface upstream the flow propagation with respect to said orifice, the volume (Vol) computed from said segmented isovelocity surface, and the peak velocity of the flow through said orifice. The surface is given by the formula: SOR=Vol. V / VREG. The system can be applied to the assessment of the surface of regurgitation of the mitral jet.

A method for continuous non-invasive monitoring of multiple arterial parameters of a patient is provided. The method includes continuously acquiring ultrasound data via an ultrasound transducer attached to the patient for detecting a blood vessel using color flow processing within a monitoring scan plane. Further, the method includes processing the continuously acquired ultrasound data to generate continuous quantitative waveforms based on an estimated cross-sectional area of the blood vessel and an estimated volumetric flow rate of blood through the vessel and displaying the generated continuous quantitative waveforms for monitoring the arterial parameters of the patient in real-time.

Methods, apparatus, and computer-readable storage media for dynamic color flow modeling. A dynamic color flow model that incorporates motion estimation in a probabilistic fashion is described. By automatically and adaptively changing model parameters based on the inferred local motion uncertainty, the dynamic color flow model accurately and reliably models the object appearance, and improves the foreground color probability estimation when compared to conventional methods. The dynamic color flow model may, for example, be applied to both foreground and background layers (or to additional layers) for video object segmentation, obtaining significantly improved results when compared to conventional methods.

A real-time signal processing technique for ultrasonic imaging of tissue vibrations for localizing the source of a bruit in a 2D image with respect to the anatomy and / or for obtaining simultaneous information about vibrations and the underlying blood flow. The bruit can be quantitatively assessed using an ensemble of ultrasound echoes. Signal processing enables estimation of wall displacement and the display of time-resolved vibration spectrum. Vibrations are detected and color-coded according to their amplitude and frequency and overlaid on the B-mode and / or color-flow image in real time. Proposed vibration imaging algorithms use data acquired during conventional ultrasonic color-flow imaging and the clutter signal, normally suppressed in color-flow imaging, to detect and characterize tissue vibrations. Three vibration imaging algorithms based on parametric modeling of vibrations and other criteria distinguish between clutter, blood flow, and vibrations. The techniques are usable to detect, locate, image, and quantitatively grade stenoses in blood vessels.

Adaptive volume rendering is provided for medical diagnostic ultrasound. The opacity of B-mode data is set relative to the opacity of Doppler data. The opacities for the different types of data are set as a function of ray depth. For example, the opacity of B-mode data near a tissue border is set to be more opaque than for tissue away from the border, and the opacity for flow data near a flow border is set to be less opaque than for flow away from the border. An image is rendered using a rendering parameter set as a function of ray depth, B-mode information and Doppler information. Other processes for enhancing and / or using rendering may be used.

An ultrasound based technique for detecting and imaging vibrations in tissue caused by eddies produced during bleeding through punctured arteries or from organs. A clutter signal, normally suppressed in conventional color flow imaging, is employed to detect and characterize local tissue vibrations, to detect internal bleeding in an image, or as an audible or palpable signal, or a readout. Using a tissue vibration image, the origin and extent of vibrations relative to the underlying anatomy and blood flow can be visualized in real time, enabling measurements of vibration amplitude, frequency, and spatial distribution. Bleeding rate can be determined from the frequency and amplitude of the vibrations. Signal processing algorithms usable to identify tissue vibrations from an ensemble of 2D ultrasound data include those based on phase decomposition, spectral estimation using eigendecomposition, and spectral estimation using autoregressive modeling for isolating vibrations from clutter, blood flow, and noise.

An ultrasound based technique for detecting and imaging vibrations in tissue caused by eddies produced during bleeding through punctured arteries or from organs. A clutter signal, normally suppressed in conventional color flow imaging, is employed to detect and characterize local tissue vibrations, to detect internal bleeding in an image, or as an audible or palpable signal, or a readout. Using a tissue vibration image, the origin and extent of vibrations relative to the underlying anatomy and blood flow can be visualized in real time, enabling measurements of vibration amplitude, frequency, and spatial distribution. Bleeding rate can be determined from the frequency and amplitude of the vibrations. Signal processing algorithms usable to identify tissue vibrations from an ensemble of 2D ultrasound data include those based on phase decomposition, spectral estimation using eigendecomposition, and spectral estimation using autoregressive modeling for isolating vibrations from clutter, blood flow, and noise.

A system and method for ultrasound clutter filtering is provided. A processor is configured to iteratively select an optimal high pass filter for the progressive, ordered filtering of clutter from ultrasound color flow imaging data. The high pass filter input for each iterative selection and ordered set of high pass filters is the same original ultrasound color flow imaging data. The high pass filters have different cutoff frequencies whereby each high pass filter can be implemented using different structures. The system and method allow for filtering of clutter from ultrasound color flow imaging data until the clutter is substantially removed.

A method for producing an ECG-triggered retrospective color-flow ultrasound image comprises generating ultrasound, transmitting the ultrasound into a subject at a first location, wherein a first reference point of an ECG signal taken from the subject triggers the ultrasound transmission, receiving ultrasound reflected from the subject at the first location, transmitting the ultrasound into the subject at a second location, wherein a second reference point of an ECG signal taken from the subject triggers the ultrasound transmission receiving ultrasound reflected from the subject at the second location, processing the received ultrasound to form ultrasound color traces, and reconstructing the ultrasound color traces to form the ultrasound image.

Aspects of the present disclosure include methods for processing a biological sample. Methods according to certain embodiments include contacting a biological sample having cells with an assay reagent that includes one or more analyte-specific binding members to produce a biological sample assay composition and introducing the biological assay composition into an inlet of a flow cytometer having an integrated acoustic separator. Systems, including a flow cytometer with integrated acoustic separator having one or more acoustic concentrator devices suitable for practicing the subject methods are also described.

The invention relates to a detection method of colon bacillus, particularly discloses a method for detecting the colon bacillus by combining magnetic nanoparticle enrichment with bi-color flow cytometry. The method comprises the following steps of: firstly co-culturing nanoparticles and samples to be measured and enriching composites formed by the magnetic nanoparticles and the samples to be measured under the action of an externally applied magnetic field; then carrying out immune co-culture and secondary enrichment on colon bacillus antibodies labelled by fluorescent nanoparticles and the enriched samples to be measured; then dyeing the secondarily-enriched samples to be measured by using nucleic acid dyes; finally detecting and viewing the dyed samples to be measured by adopting the multi-parameter flow cytometry and a laser confocal microscope, and analyzing and judging detection results of the colon bacillus contained in the samples to be measured according to the number of detected objects with fluorescent double-positive signals. The detection method has the advantages of rapidness, accuracy, sensitivity, low false positive rate, and the like.

A method for continuous non-invasive monitoring of multiple arterial parameters of a patient is provided. The method includes continuously acquiring ultrasound data via an ultrasound transducer attached to the patient for detecting a blood vessel using color flow processing within a monitoring scan plane. Further, the method includes processing the continuously acquired ultrasound data to generate continuous quantitative waveforms based on an estimated cross-sectional area of the blood vessel and an estimated volumetric flow rate of blood through the vessel and displaying the generated continuous quantitative waveforms for monitoring the arterial parameters of the patient in real-time.

Systems and methods for enhanced color-flow imaging of contrast-agent perfused blood vessels and other tissues within a patient's body are disclosed. The method generally comprises, introducing one or more contrast agents into the body, power-modulating transmit pulses into the body, receiving echoes from the body, processing the received echoes to reduce tissue-generated echoes and echoes from stationary contrast agent, using a color-flow processor to generate a color-encoded display responsive to contrast-agent motion. The method may be implemented by a system with a an excitation-signal source, a transducer, an ultrasound-processing system having multiple image processors including a color-flow processor, as well as, a clutter filter, and an arbiter, and a display-processing system.

The invention relates to a viewing system having means for processing a sequence of three-dimensional (3-D) ultrasound images for performing a quantitative estimation of a flow in a body organ. In particular, the invention relates to a medical viewing system and to an image processing method for performing an automatic quantitative estimation of the blood flow through the heart values, and / or of the regurgitant jet, from a sequence of 3-D color flow images. The invention particularly finds an application in the field of medical imaging in cardiology using ultrasound medical apparatus and / or viewing systems.

Methods, apparatus, and computer-readable storage media for dynamic color flow modeling. A dynamic color flow model that incorporates motion estimation in a probabilistic fashion is described. By automatically and adaptively changing model parameters based on the inferred local motion uncertainty, the dynamic color flow model accurately and reliably models the object appearance, and improves the foreground color probability estimation when compared to conventional methods. The dynamic color flow model may, for example, be applied to both foreground and background layers (or to additional layers) for video object segmentation, obtaining significantly improved results when compared to conventional methods.

Systems and methods for determining scan parameters to be used during image acquisition are provided. Values of imaging effects can be input using user controls accessible from a user interface. A processor can determine scan parameters to be used during image acquisition based on the input imaging effect values. The determined scan parameters can be displayed using the user interface. Values of imaging effects and potential ranges of values of imaging effects can be constrained based on selected values of other imaging effects. Imaging effects can include image resolution, image penetration, frame rate and / or color flow sensitivity. Scan parameters can include: line density, number of focal zones, frequency, dynamic range, pulse repetition frequency, and / or number of compounding angles. An ultrasound imaging system can be used to acquire images using the determined scan parameters.

A system, an apparatus, and a method are provided for a modular flow cytometer with a compact size. In one embodiment, the modular flow cytometry system includes the following: a laser system for emitting laser beams; a flow cell assembly positioned to receive the laser beams at an interrogation region of a fluidics stream where fluoresced cells scatter the laser beams into fluorescent light; a fiber assembly positioned to collect the fluorescent light; and a grating system including a dispersive element and a receiver assembly, wherein the dispersive element is positioned to receive the fluorescent light from the fiber assembly and to direct spectrally dispersed light toward the receiver assembly.

Disclosed herein is the iterative selection of an optimal high pass filter for progressive, ordered filtering of clutter from ultrasound color flow imaging data wherein a criterion for selecting the optimal high pass filter is if a mean frequency of filtered signal data is less than a clutter frequency threshold wherein if the mean frequency is less than the clutter frequency threshold is determined by whether an absolute value of an imaginary part of a first order autocorrelation of the filtered signal data is less than a constant times a real part of the autocorrelation, where the constant is determined by the clutter frequency threshold, wherein a high pass filter input for each iterative selection is the original ultrasound color flow imaging data.

The present invention relates to a method and an ultrasound diagnostic system for displaying a 3-dimensional color flow image performing a transparency treatment for a predetermined region. The method of displaying a color flow image, comprises: a) forming a plurality of 2-dimensional color flow images based on ultrasound echo signals; b) sequentially superposing the plurality of 2-dimensional color flow images to form a 3-dimensional color flow image including a plurality of image regions; c) receiving selection information for selecting a desirable image region from the 3-dimensional color flow image; and d) performing a transparency treatment upon the selected region in the 3-dimensional color flow to have a predetermined transparency.

The present invention relates to a method and apparatus for performing motion adaptive frame averaging for ultrasound color flow images used to overcome lag and smearing alias of color due to motion. One embodiment of the present invention comprises an ultrasound machine for generating an color flow imaging responsive to moving tissue. The ultrasound system comprises a front end and at least one processor. The front-end is arranged to transmit ultrasound waves into the moving tissue, generating received signals in response to the ultrasound waves backscattered from the moving tissue. The processor is responsive to the received signals, calculating a motion factor by comparing at least one current b-mode frame with at least one previous b-mode frame, determining motion using at least the motion factor, increasing a level of frame averaging if the motion factor is below a first predetermined threshold, and decreasing the level of frame averaging if the motion factor is above a second predetermined threshold.

The invention discloses an acute B-lymphocyte leukemia initiated cell phenetic classification kit. The kit is used in cooperation with a sever-color flow cytometer. The structure of the kit is configured with the following fluorescently-labeled monoclonal antibody: CD58FITC, CD10PE, CD34PerCP, CD38APC, CD19APC-Cy7 and CD45PacificBlue. The kit disclosed by the invention can be used for fast and accurately detecting the immunophenotype of the leukemia initiated cell of a B-ALL patient in first visit; and the CD58 expression proportion on the leukemia initiated cell tested by the kit provided by the invention can be used as one of the prognostic indicators of the B-ALL patient, and the indicator has important guiding significance in the prognosis of the B-ALL patient and the decision of a clinic treatment scheme.

An array type printhead includes a first member including a plurality of inflow holes through which inks of different colors flow, a second member including a plurality of channels formed on a top surface thereof to receive the inks of different colors from the plurality of inflow holes of the first member, and a plurality of outflow holes through which the received inks flow, a third member including a plurality of path grooves formed on a top surface thereof through which the inks of different colors flow from the second member, and a plurality of supply holes formed in corresponding ones of the plurality of path grooves, each supply hole to supply one head chip nozzle line with ink of one color, and at least one head chip mounted on a bottom surface of the third member and comprising a plurality of nozzles arranged in a plurality of lines in a lengthwise direction of the printhead corresponding to a widthwise direction of a printing medium to eject the inks of different colors, the first, second, and third members being layered on top of each other.

Disclosed is an ultrasonic diagnostic device, provided with: a transmitting / receiving unit which repeatedly drives a probe, receives through the probe reflected echoes obtained as the ultrasound wave transmitted by means of driving the probe reflects off a subject, and sequentially generates a plurality of receiving signals; a color flow mapping signal processing unit which sequentially generates blood flow rate data of the blood flow portion of the subject's body for each frame on the basis of the plurality of received signals; a remaining image processing unit which processes the remaining images for each frame with respect to the blood flow rate data; a tomographic image signal processing unit which generates a B-mode tomographic image frame data on the basis of the receiving signals; and an image synthesizing unit which synthesizes the blood flow rate data that was processed by the remaining image processing unit and the B-mode tomographic image frame data. The remaining image processing unit performs a folding assessment on the basis of the blood flow rate data of the newest frame and the blood flow rate data that was processed by the remaining image processing unit of the frames before the newest frame and dynamically changes the coefficient of persistence on the basis of the results of the folding assessment and the blood flow rate data of the newest frame and the frames therebefore.

A method and an apparatus for performing pulsed-wave spectral Doppler imaging at every color flow range gate location in a two-dimensional (or three-dimensional) region of interest. Spectral processing is necessary to determine the flow parameters. Performing this processing at every color flow range gate location creates the two-dimensional image. The method generates two-dimensional images of flow parameters such as peak velocity, pulsatility index, resistance index, etc. With the two-dimensional image, the user immediately observes where the most critical value of the flow parameter occurs and what that value is.

A medical ultrasound viewing system for processing a sequence of three-dimensional (3-D) ultrasound images far performing a quantitative estimation of a flow through a body organ comprising means for performing steps of acquiring a sequence of 3D color flow images, of said flow; assessing the flow velocity values in the 3D images, constructing isovelocity surfaces (6) by segmentation of the flow velocity values; computing the volume (Vol) delimited by the isovelocity surfaces; and using the flow velocity value (V) and the volume (Vol) computed from a segmented surface for computing the surface of an orifice (3) of the organ through which the flow propagates. The viewing system further comprises means for performing steps of measuring the peak velocity (VREG) of said flow through said orifice; computing the surface of the orifice (SOR) through which the flow propagates as a function of the flow velocity value (V) at an isovelocity surface upstream the flow propagation with respect to said orifice, the volume (Vol) computed from said segmented isovelocity surface, and the peak velocity of the flow through said orifice. The surface is given by the formula: SOR=Vol. V / VREG. The system can be applied to the assessment of the surface of regurgitation of the mitral jet.

The invention provides an antibody composition, and applications thereof in Lymphoplasmacytic Lymphoma minimal residual detection. Based on a plurality of years of clinical practice and research, twotubes eight colors 16 antibody compositions are obtained via screening, and high efficiency high sensitivity distinguishing identifying of abnormal cell population is realized; on the above base, FITC, PE, Percp5.5, Pe-cy7, APC, AF750, BV421, and V500 fluorescent labels are selected preferably, and results of eight kinds of antibodies are obtained in detection of one flow tube in an eight color flow cytometry single tube. In addition, a corresponding analysis method of the detection results is designed based on 45 / SSC combination, so that it is possible to determine whether plasmocyte, B lymphocyte clonality, and abnormal lymphoplasmacytoid are detected. The antibody composition can be directly used for MRD detection of LPL, and can also be used for preparation of related kits.

The invention relates to the field of minimal residual disease (MRD) diagnostics, which is progressively more applied for the evaluation of treatment effectiveness in patients with a hematological malignancy, such as B-cell precursor acute lymphoblastic leukemia (BCP-ALL), B-cell chronic lymphocytic leukemia (B-CLL), and multiple myeloma (MM). Provided are unique reagent compositions with carefully selected and thoroughly tested combinations of antibodies, for >=8 color flow cytometric stainings as well as for 10-color and 12-color flow cytometric stainings, which can reach sensitivities of at least 10<-4>, even down to 10<-5>. Also provided are diagnostic kits and methods for detecting MRD.

The present invention relates to latex compositions comprising hydroxyethyl cellulose grafted acrylic polymer emulsions and methods for preparing same without gelling or coagulation. The latex composition comprises at least about 0.2% of HEC by weight relative to the monomer weight, contains at least about 45% solid, and the average mean volume (mV) latex particle size is in the range of about 320-about 850 nm. Paint compositions incorporating the HEC grafted acrylic latex show high viscosity at static conditions and have no color flow and no syneresis compared paints containing a latex without HEC grafting. The present invention also relates to a cross-linking mechanism that cross-links latex particles at ambient conditions. This cross-linking mechanism comprises diacetone acrylamide (DAAM) and methacrylamide (MAM) with or without styrene.