5 results about "Body organs" patented technology

The present invention relates to an artificial contractile device comprising at least one contractile element (1) comprising a flexible strip (4) extending in a longitudinal direction and a closure (6) for forming the contractile element (1) into a closed loop around a hollow body organ, the closure (6) being situated at a first extremity of the flexible strip (4). The contractile element is adapted to contract a hollow body organ, in such a way that said contractile element (1) may be in a resting position or in an activated position. The artificial contractile device further comprises a flexible transmission (3) comprising a tensioning element (31) being anchored at a first end (311) to a first anchoring point (A) on the flexible strip (4), said flexible transmission (3) being adapted to tighten the contractile element (1) formed in a closed loop around said hollow body organ upon application of a traction force at and end of the tensioning element (2031) by an actuator (7). The artificial contractile device also comprises a connector (5) adapted to connect the flexible transmission (3) to a said actuator (7), a second end (312) of said tensioning element (2031) being anchored in said connector (5).

Apparatuses and methods for facilitating the guided delivery of a drug into a patient's body organ are disclosed. An apparatus (2500) for facilitating the guided delivery of a drug into a patient's body organ can include a container (2504) configured to package a drug, a needle (2502) having a passage therethrough and a sharp distal tip, and a needle sheath (2506) at least partially surrounding a shaft of the needle. The needle sheath can include a distal surface, wherein the sharp distal tip of the needle can be configured to extend through an opening in the distal surface. The needle sheath can be movable relative to the needle along an axis of the needle to control a distance from the distal surface to the distal tip of the needle.

The application belongs to the technical field of animal vaccine preparation, and discloses an African swine fever virus (ASFV) multi-epitope fusion protein, a ferritin nanoparticle vaccine of the ASFV multi-epitope fusion protein and application. The application obtains 16 dominant B cell epitopes by using an ASFV phage display library in combination with reverse screening of clinical positive serum, and constructs a nanoparticle vaccine by linking the 16 epitopes with ferritin self-assembly. The vaccine has excellent biosafety, can induce high-level and sustained specific antibodies and significant IFN-gamma cellular immune response in pigs, can effectively delay the clinical onset and death process of pigs in ASFV virulent challenge experiments, and can significantly reduce the virus load in whole-body organ tissues, thereby providing 25% survival protection rate. The application provides an effective new strategy for the development of a subunit vaccine for responding to various ASFV mutant strains.

The present invention provides an improved vascular occlusion device having improved flexibility and retention of the type fabricated from braided tubular metal fabric having an expanded preset configuration and an elongated collapsed reduced diameter configuration for delivery through a catheter to a treatment site and shaped to create an occlusion of an abnormal opening in a body organ or vessel, the woven metal fabric having a memory property whereby the medical device tends to return to said expanded preset configuration when unconstrained. The device further including at least one disk portion adjacent a body cylindrical portion formed from the fabric and having a transition diameter between the disk and cylindrical portion, significantly smaller than the diameter of the disk and the diameter of the cylindrical portion.