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712 results about "Particle composition" patented technology
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A composition comprises a non-aqueous solvent containing reverse micelle particles formed of block polymers having amphipathic properties. A particle composition and a composition wherein particles are dispersed, which exhibits excellent dispersion properties and can form superbly uniform particles, is provided.
Scaffolded nucleic acid polymer particles and methods of making and using
ActiveUS20100304982A1Bioreactor/fermenter combinationsSequential/parallel process reactionsParticle compositionPolynucleotide
The invention provides particle compositions having applications in nucleic acid analysis. Nucleic acid polymer particles of the invention allow polynucleotides to be attached throughout their volumes for higher loading capacities than those achievable solely with surface attachment. In one aspect, nucleic acid polymer particles of the invention comprise polyacrylamide particles with uniform size distributions having low coefficients of variations, which result in reduced particle-to-particle variation in analytical assays. Such particle compositions are used in various amplification reactions to make amplicon libraries from nucleic acid fragment libraries.
Owner:LIFE TECH CORP
Light-emitting nanoparticles and method of making same
InactiveUS6846565B2Reduce aggregationResist formationMaterial nanotechnologyLiquid surface applicatorsParticle compositionHigh pressure
A method for the production of a robust, chemically stable, crystalline, passivated nanoparticle and composition containing the same, that emit light with high efficiencies and size-tunable and excitation energy tunable color. The methods include the thermal degradation of a precursor molecule in the presence of a capping agent at high temperature and elevated pressure. A particular composition prepared by the methods is a passivated silicon nanoparticle composition displaying discrete optical transitions.
Owner:MERCK PATENT GMBH +1
Biomass Char Compositions for Catalytic Gasification
InactiveUS20090217575A1Efficient utilization of carbonEfficient comprehensive utilizationProductsReagentsParticulatesHydrogen
Particulate compositions are described comprising an intimate mixture of a biomass char producedfrom the combustion of a biomass, such as switchgrass or hybrid poplar, with at least a second carbonaceous material, such as petroleum coke or coal, and, optionally a gasification catalyst, for gasification in the presence of steam to yield a plurality of gases including methane and at least one or more of hydrogen, carbon monoxide, and other higher hydrocarbons are formed. Processes are also provided for the preparation of the particulate compositions and converting the particulate composition into a plurality of gaseous products.
Owner:SURE CHAMPION INVESTMENT LTD
Compositions and methods relating to reduced mucoadhesion
InactiveUS20120121718A1Reduced mucoadhesionDiffusion fastOrganic active ingredientsPowder deliveryMedicineParticle composition
The present invention generally relates to reducing the mucoadhesive properties of a particle. In some embodiments, the particle is coated with and / or associated with a (poly(ethylene glycol))-(poly(propylene oxide))-(poly(ethylene glycol)) triblock copolymer. Methods for preparing inventive particles using a poly(ethylene glycol)-vitamin E conjugate as a surfactant are also provided. In some embodiments, methods are provided comprising administering to a subject a composition of particles of the present invention. Such particles with reduced mucoadhesive properties are useful in delivering agents to mucosal tissues such as oral, ophthalmic, gastrointestinal, nasal, respiratory, and genital mucosal tissues.
Owner:THE JOHN HOPKINS UNIV SCHOOL OF MEDICINE
Compositions for Catalytic Gasification of a Petroleum Coke
InactiveUS20090090056A1Cost-effective and high-yielding productionPromote gasificationHydrogenGaseous fuelsParticle compositionMethane gas
The present invention relates to particulate compositions of a lower ash type petroleum coke containing at least two preselected components (alkali metal and calcium) that exhibit an efficient, enhanced-yielding gasification to value added gaseous products, particularly when used in a steady-state integrated gasification process. The compositions of the present invention are particularly useful for catalytic gasification of petroleum coke at moderate temperatures ranging from about 450° C. to about 900° C. Advantageously, the compositions can be readily incorporated into fluidized bed gasification units, and can result in a cost-effective, high-yielding production of methane gas from petroleum coke.
Owner:SURE CHAMPION INVESTMENT LTD
Applications of light-emitting nanoparticles
InactiveUS6918946B2Reduce aggregationResist formationMaterial nanotechnologyPolycrystalline material growthParticle compositionHigh pressure
A method for the production of a robust, chemically stable, crystalline, passivated nanoparticle and composition containing the same, that emit light with high efficiencies and size-tunable and excitation energy tunable color. The methods include the thermal degradation of a precursor molecule in the presence of a capping agent at high temperature and elevated pressure. A particular composition prepared by the methods is a passivated silicon nanoparticle composition displaying discrete optical transitions.
Owner:KORGEL BRIAN A +1
Petroleum Coke Compositions for Catalytic Gasification
Particulate compositions are described comprising an intimate mixture of a petroleum coke and an alkali metal gasification catalyst, where the alkali metal gasification catalyst comprises a combination of an alkali metal hydroxide and one or more other alkali metal compounds are loaded onto coke for gasification in the presence of steam to yield a plurality of gases including methane and at least one or more of hydrogen, carbon monoxide, and other higher hydrocarbons are formed. Processes are also provided for the preparation of the particulate compositions and converting the particulate composition into a plurality of gaseous products.
Owner:SURE CHAMPION INVESTMENT LTD
Hypochlorite Technology
This invention generally relates to compositions and method of producing diluted hypohalous acid and hypohalous acid vapor. These compositions can be used to treat allergen containing surfaces, hard surfaces, food contact surfaces, hospital surfaces, food surfaces, kitchen surfaces, bathroom surfaces, human surfaces, animal surfaces, children's items, outdoor surfaces, soft surfaces, and medical instruments. These compositions can be converted to solid particulate or granular compositions. These compositions can be put into a variety of containers which preserve the stability. These compositions can be used to treat allergens and molds and as part of a mold detection system. These compositions can be dispersed into the air to enable microbiological control.
Owner:BROMBERG STEVEN E +29
Microfluidic Synthesis of Organic Nanoparticles
ActiveUS20100022680A1Minimum of laborMinimum of timeCosmetic preparationsMaterial nanotechnologyNanoparticleParticle composition
The present invention provides microfluidic systems and methods for the production of particles (e.g., nanoparticles) for drug delivery. The present invention provides microfluidic devices useful for production of particles by nanoprecipitation. The present invention provides highly homogenous compositions of particles produced by inventive microfluidic devices.
Owner:THE BRIGHAM & WOMEN S HOSPITAL INC +1
Coal Compositions for Catalytic Gasification
Particulate compositions are described comprising an intimate mixture of a coal and a gasification catalyst. The particulate compositions are gasified in the presence of steam to yield a plurality of gases including methane and at least one or more of hydrogen, carbon monoxide, carbon dioxide, hydrogen sulfide, ammonia and other higher hydrocarbons. Processes are also provided for the preparation of the particulate compositions and converting the particulate composition into a plurality of gaseous products.
Owner:SURE CHAMPION INVESTMENT LTD
Biomass Compositions for Catalytic Gasification
Particulate compositions are described comprising an intimate mixture of a biomass, such as switchgrass or hybrid poplar, a non-biomass carbonaceous material, such as petroleum coke or coal, and a gasification catalyst, where the gasification catalyst is loaded onto at least one of the biomass or non-biomass for gasification in the presence of steam to yield a plurality of gases including methane and at least one or more of hydrogen, carbon monoxide, and other higher hydrocarbons are formed. Processes are also provided for the preparation of the particulate compositions and converting the particulate composition into a plurality of gaseous products.
Owner:SURE CHAMPION INVESTMENT LTD
Carbonaceous Fines Recycle
ActiveUS20090217589A1Sufficient amountHydrogen productionCarbon monoxideParticulatesParticle composition
Owner:SURE CHAMPION INVESTMENT LTD
Combinations and modes of administration of therapeutic agents and combination therapy
InactiveUS20070166388A1Heavy metal active ingredientsOrganic active ingredientsNanoparticleAnti vegf antibody
The present invention provides combination therapy methods of treating proliferative diseases (such as cancer) comprising a first therapy comprising administering to an individual an effective amount of a taxane in a nanoparticle composition, and a second therapy which may include, for example, radiation, surgery, administration of chemotherapeutic agents (such as an anti-VEGF antibody), or combinations thereof. Also provided are methods of administering to an individual a drug taxane in a nanoparticle composition based on a metronomic dosing regime.
Owner:ABRAXIS BIOSCI LLC
Polymer composition for encapsulation of electrode particles
InactiveUS20050034993A1Pigmenting treatmentElectrode carriers/collectorsRefractive indexParticle composition
Compositions and methods are provided for coating electroactive particles. Coating materials include a conductive component and a low refractive index component. Coatings are provided in which the conductive and low refractive index components are linked and / or do not form phases having lengthscales greater than about 0.25 μm. Coatings are provided in which the components are contained in sequential layers.
Owner:A123 SYSTEMS LLC
Method for surface crosslinking water-absorbing resin and method for manufacturing water-absorbing resin
ActiveUS20070149760A1Good physical propertiesShorten heat treatment timeTransportation and packagingRotary stirring mixersParticulatesParticle composition
A method for surface crosslinking water-absorbing resin of the present invention includes a step (1) of obtaining a wet mixture, a step (2) of obtaining a dried particulate composition, and a step (3) of carrying out a surface crosslinking reaction. With this, since a processing time of each step becomes short, it is possible to mass produce the water-absorbing resin having excellent physical properties. Moreover, a method for manufacturing the water-absorbing resin of the present invention includes a modifying step and a cooling step. The modifying step and / or the cooling step are / is carried out by using stirring means including a rotation axis having a plurality of stirring boards, and the stirring means includes the stirring board having a specific thickness and / or a scraping blade having a specific shape. With this, it is possible to suppress the generation of the fine powder in the modifying step and / or the cooling step.
Owner:NIPPON SHOKUBAI CO LTD
Compositions and methods relating to reduced mucoadhesion
InactiveUS20130236556A1Reduced mucoadhesionDiffusion fastBiocidePowder deliveryMedicineParticle composition
The present invention generally relates to reducing the mucoadhesive properties of a particle. In some embodiments, the particle is coated with and / or associated with a (poly(ethylene glycol))-(poly(propylene oxide))-(poly(ethylene glycol)) triblock copolymer. Methods for preparing inventive particles using a poly(ethylene glycol)-vitamin E conjugate as a surfactant are also provided. In some embodiments, methods are provided comprising administering to a subject a composition of particles of the present invention. Such particles with reduced mucoadhesive properties are useful in delivering agents to mucosal tissues such as oral, ophthalmic, gastrointestinal, nasal, respiratory, and genital mucosal tissues.
Owner:THE JOHN HOPKINS UNIV SCHOOL OF MEDICINE
Amphiphilic polymer micelles and use thereof
InactiveUS20080160305A1Improve high temperature performanceImprove propertiesMaterial nanotechnologySynthetic resin layered productsElastomerThermoplastic
A nano-particle composition including a polar core and a hydrophobic surface layer is provided. The nano-particles have a mean average diameter less than about 100 nm. Methods are disclosed for making and using the nano-particles. The nano-particles can be modified via, for example, hydrogenation or functionalization. The nano-particles can advantageously be incorporated into rubbers, elastomers, and thermoplastics.
Owner:BRIDGESTONE CORP
Surface modified particulate compositions of biologically active substances
InactiveUS20060210622A1Easy to useEfficient deliveryPowder deliveryOrganic active ingredientsParticulatesWater insoluble
This invention disclosure relates to compositions for the delivery of stable surface modified sub-micron and micron sized particles of water-insoluble biologically active substances from a non-aqueous medium that self-disperses on exposure to an aqueous environment.
Owner:SKYEPHARMA CANADA INC
Process for the preparation of a granulate suitable to the preparation of rapidly disintegrable mouth-soluble tablets and compositions obtained thereby
InactiveUS6149938AGood water solubilityPill deliveryPharmaceutical non-active ingredientsParticle compositionSoluble Tablet
A process for making a granulate composition suitable to the preparation of an oral solid form that can disintegrate rapidly inside the buccal cavity is provided as well as the granulate compositions and obtained.
Owner:ALPEX PHARMA SA
Multi-layer nano-particle preparation and applications
InactiveUS6872785B2Reduced shrinkage performanceImprove lagMaterial nanotechnologySpecial tyresThermoplasticElastomer
A multi-layer nano-particle composition including a polymer core and at least two additional layers is provided. The nano-particles have a mean average diameter less than about 100 nm. The nano-particles can be modified via, for example, hydrogenation or functionalization. The nano-particles can be advantageously incorporated into rubbers, elastomers, and thermoplastics.
Owner:BRIDGESTONE CORP
Particles, compositions and methods for ophthalmic and/or other applications
InactiveUS20130316001A1Improves ocular bioavailabilityImprove concentrationNanotechSenses disorderDrug deliveryOphthalmology
Particles, compositions, and methods that aid particle transport in mucus are provided. The particles, compositions, and methods may be used, in some instances, for ophthalmic and / or other applications. In some embodiments, the compositions and methods may involve modifying the surface coatings of particles, such as particles of pharmaceutical agents that have a low aqueous solubility. Such compositions and methods can be used to achieve efficient transport of particles of pharmaceutical agents though mucus barriers in the body for a wide spectrum of applications, including drug delivery, imaging, and diagnostic applications. In certain embodiments, a pharmaceutical composition including such particles is well-suited for ophthalmic applications, and may be used for delivering pharmaceutical agents to the front of the eye and / or the back of the eye.
Owner:ALCON INC
Nanoparticles for therapeutic and diagnostic applications
InactiveUS20060222595A1Easy to useFacilitate multiple modeUltrasonic/sonic/infrasonic diagnosticsMaterial nanotechnologyDiagnostic agentProviding material
This document provides materials and methods related to nanoparticles. For example, nanoparticle compositions, methods for making nanoparticle compositions, and methods for using nanoparticle compositions are provided. In some cases, the nanoparticles are gold (e.g., colloidal gold) nanoparticles. A nanoparticle can include one or more agents linked to its surface, such as therapeutic and / or diagnostic agents, and can be from about 1 nm to about 10 nm in size.
Owner:MAYO FOUND FOR MEDICAL EDUCATION & RES
Particulate compositions for pulmonary delivery
ActiveUS7182961B2Maximize drug deliveryWall thickness can be minimizedPowder deliveryPharmaceutical product form changeParticulatesMedicine
This invention concerns an improved particulate composition for delivering a drug to the pulmonary system. Applicants disclose a method of identifying an optimal form of aerodynamically light particles which are highly dispersible. The particles of the instant invention are made by creating hollow, spherical drug particles (i.e., progenitor particles) that collapse in the process of particle formation, leading to wrinkled, thin-walled drug particles of very low envelope density. Additionally, Applicants have found that such particles are especially optimal for inhaled aerosols when the surface area parameter (σ) is greater than 2, optimally greater than 3.
Owner:CIVITAS THERAPEUTICS
Medical devices having a metal particulate composition for controlled diffusion
An implantable or insertable medical device is provided which includes as components: (a) a substrate component comprising a depression that is at least partially filled with a therapeutic agent-containing material that comprises a first therapeutic agent, and (b) a particulate composition disposed in the depression such that it regulates transport of chemical species between the depression and the exterior of the device upon implantation or insertion of the device into a subject.
Owner:BOSTON SCI SCIMED INC
Magnetic particle composition for therapeutic hyperthermia
InactiveUS20050249817A1Heat generationHeavy metal active ingredientsBiocideHysteresisMagnetite Nanoparticles
Magnetic nanoparticle compositions are provided which provide an inherent temperature regulator for use in magnetic heating, particularly for use in magnetic hyperthermia medical treatments. The composition includes magnetic nanoparticles having a Curie temperature of between 40 and 46° C., preferably about 42° C., and may further include a polymeric material and optionally a drug or radiosensitizing agent. Methods of hyperthermia treatment of a patient in need thereof are provided which include the steps of administering to the patient a composition comprising magnetic nanoparticles having a Curie temperature of between 40 and 46° C.; and exposing the magnetic nanoparticles in the patient to an alternating magnetic field effective to generate hysteresis heat in the nanoparticles.
Owner:FLORIDA STATE UNIV RES FOUND INC
Scaffolded Nucleic Acid Polymer Particles and Methods of Making and Using
InactiveUS20110195253A1Sequential/parallel process reactionsMicrobiological testing/measurementParticle compositionPolynucleotide
The invention provides particle compositions having applications in nucleic acid analysis. Nucleic acid polymer particles of the invention allow polynucleotides to be attached throughout their volumes for higher loading capacities than those achievable solely with surface attachment. In one aspect, nucleic acid polymer particles of the invention comprise polyacrylamide particles with uniform size distributions having low coefficients of variations, which result in reduced particle-to-particle variation in analytical assays. Such particle compositions are used in various amplification reactions to make amplicon libraries from nucleic acid fragment libraries.
Owner:LIFE TECH CORP
Granular controlled release agrochemical compositions and process for the preparation thereof
A granular agrochemical composition is disclosed including a granular core material having a water soluble portion with a first coating layer applied on the surface of the core material and a second coating layer applied on the surface of the first coating layer. The first coating layer includes a wax composition having a biologically active ingredient incorporated therein and the second coating layer includes a polymeric composition. The granular agrochemical composition exhibits a controlled rate of release of the biologically active ingredient therefrom over a period greater than about 30 days from the date of initial exposure of the granular composition to moisture whereby essentially all of the biologically active ingredient incorporated in the wax material of the first coating layer is released from the granular composition before the water soluble portion of the granular core material is released from the granular composition.
Owner:EVERRIS INT
Methods of enhancing drug delivery and effectiveness of therapeutic agents
ActiveUS20120076862A1Promote absorptionConvenient treatmentPowder deliveryHeavy metal active ingredientsDiseaseCo administration
The present invention in one aspect provides methods of enhancing uptake of a therapeutic agent in a target tissue as well as methods of treating a disease (such as cancer) or enhancing effectiveness of treatment with a therapeutic agent in an individual by co-administering a composition comprising nanoparticles comprising albumin and a poorly water soluble drug such as a taxane with the therapeutic agent. The present invention in another aspect provides a method of treatment or a method of selecting patients for treatment of a disease (such as cancer) with the combination of a therapeutic agent and a composition comprising nanoparticles comprising albumin and a poorly water soluble drug such as a taxane based on one or more characteristics of the target tissue that correlates or indicates the capability of getting enhanced therapeutic agent uptake as a result of the co-administration of the taxane nanoparticle composition in the target tissue (referred to as “the drug uptake capability”). Also provided are pharmaceutical compositions, article of manufacture, and kits useful for methods described herein.
Owner:ABRAXIS BIOSCI LLC
Flame-Retardant Magnesium Hydroxide Compositions and Associated Methods of Manufacture and Use
InactiveUS20070176155A1Improve resistance performanceSuitable for usePigmenting treatmentGlass/slag layered productsParticulatesPolymer resin
The invention provides a submicron magnesium hydroxide particulate composition comprising a first distribution of magnesium hydroxide particles having a D50 of no more than about 0.30 μm, a D90 of no more than about 1.5 μm, and a BET surface area of at least about 35 m2 / g, which can be used as a flame-retardant additive for synthetic polymers, optionally in combination with other flame-retardant additives such as nanoclays and larger-sized magnesium hydroxide particulate compositions. Polymeric resins comprising the submicron magnesium hydroxide particles and methods of manufacturing submicron magnesium hydroxide particles are also provided.
Owner:MARTIN MARIETTA MATERIALS
Degradable particulates as friction reducers for the flow of solid particulates and associated methods of use
InactiveUS20070238623A1Improving particulate flowRelieve pressureFluid removalFlushingParticulatesSolid particle
Particulate compositions that comprise macro-particulates, and degradable particulates in an amount sufficient to reduce friction between the macro-particulates, the degradable particulates having a mean particle diameter of at least about 20 times smaller than the mean particle diameter of the macro-particulates are disclosed herein. Also disclosed are fluids that comprise a liquid component, and a particulate composition, the particulate composition comprising macro-particulates and degradable particulates having a mean particle diameter of at least about 20 times smaller than the mean particle diameter of the macro-particulates, wherein the degradable particulates are present in the particulate composition in an amount sufficient to reduce friction between the macro-particulates. Methods of using the particulate compositions and fluids are also disclosed.
Owner:HALLIBURTON ENERGY SERVICES INC
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