182results about How to "Wide excitation spectrum" patented technology

The invention discloses a method for highly sensitive quantitative detection of quantum dot fluorescence immunochromatographic assay. The method includes: building a fluorescence immunochromatographic assay test strip on the basis of optimizing the structure of the test strip and components by the aid of excellent fluorescent characteristics of quantum dots and by means of combining quantum dot fluorescence labeling technology and immunochromatographic assay; detecting fluorescence signal strength of a quantitative belt and a quality control belt by the aid of a fluorescence quantometer and correcting the fluorescence strength of the quantitative belt by the aid of the quality control belt after immunochromatographic assay of the test strip; and further quantitatively detecting analyte according to a standard curve obtained by the fluorescence quantometer. The method is simple, rapid, accurate, low in cost and quite high in sensitivity. Compared with a conventional colloidal gold immunochromatographic assay method, the method has the advantages of fine labeling stability, low non-specificity, high sensitivity, wide linear range and accuracy in quantization. The method is applicable to samples such as blood samples, urine samples, spittle, excrement and the like, and can be applied to detection of critical illness, poison, food safety and the like.

The invention discloses a quantum dot multicolor marking method for quantitative detection of various cardiovascular disease markers and a kit of troponin I/creatine kinase isoenzyme/myohemoglobin. The method realizes fluorescent quantitative detection by utilizing excellent fluorescent properties of quantum dots and combining a multicolour marking technology and an immunochromatographic assay on the basis of optimizing each component of a test strip. Compared with the common collaurum immunochromatographic assay, the method has the advantages of good mark stability, low nonspecificity, high sensitivity, wide linear range, small cross interference, and accuracy in quantification. The kit disclosed by the invention is used for carrying out quantification detection on the troponin I, the creatine kinase isoenzyme and the myohemoglobin simultaneously, is suitable for detection of whole blood, blood serum and plasma samples, can provide a reference for cardiovascular and cerebrovascular disease diagnosis, and is widely applied to primary hospitals and clinics.

The invention discloses a fluorescent immunochromatography method for whole quantitative detection of C-reactive protein and a reagent kit thereof. The fluorescent immunochromatography method for the whole quantitative detection of the C-reactive protein (CRP) utilizes excellent fluorescent characteristics of quantum dots, and combines double-color marking technology and immunochromatography technology to achieve fluorescent quantitative detection on the basis of optimizing each constituent elements of test paper. Compared with a conventional colloidal gold immunochromatography method, the fluorescent immunochromatography method for the whole quantitative detection of the CRP has the advantages of being good in stability, low in non-specificity, high in flexibility, wide in linear range and accurate in quantifying. The reagent kit of the fluorescent immunochromatography method can perform the whole quantifying and can simultaneously predict and evaluate infectious diseases, antibiotic effects and cardiovascular and cerebrovascular diseases. The fluorescent immunochromatography method for the whole quantitative detection of the CRP and the reagent kit of the fluorescent immunochromatography method are suitable for various-level hospitals, and particularly contribute to wide popularization in basic-level hospitals and clinics.

The invention discloses a fluorescence immunochromatographic assay method for quantitatively detecting hFABP (heart fatty acid binding protein) and a kit for quantitatively detecting the same. The fluorescence immunochromatographic assay method for quantitatively detecting the hFABP realizes quantitative fluorescence detection on the basis of optimizing components of a test strip by the aid of excellent fluorescent characteristics of quantum dots and by means of combining bicolor labeling technique and immunochromatographic assay. Compared with a conventional colloidal gold immunochromatographic assay method, the fluorescence immunochromatographic assay method has the advantages of fine labeling stability, low non-specificity, high sensitivity, wide linear range and accuracy in quantization. The kit is used for quantitatively detecting the hFABP, can be used for simultaneously detecting whole blood, blood serum and plasma samples, serves as a simple, accurate, specific and inexpensive detecting tool for early screening and prognosis evaluation of acute myocardial infarction, is applicable to hospitals at all levels, and is particularly beneficial to wide popularization in primary hospitals and clinics.

The invention discloses a fluorescence immunochromatographic assay and kit for quantitatively detecting acute myocardial infarction marker, namely, N-terminal pro brain natriuretic peptide (NT-proBNP). The fluorescence immunochromatographic assay for quantitatively detecting the NT-proBNP realizes fluorescence quantitative detection on the basis of optimizing various constituent parts of test paper by using excellent fluorescence characteristic of quantum dots and combining a bicolor marking technology and an immunochromatographic technology. Compared with the conventional colloidal gold immunochromatographic assay, the fluorescence immunochromatographic assay disclosed by the invention has the advantages of good marking stability, low non-specificity, high sensitivity, wide linear range and quantifying accuracy. The fluorescence immunochromatographic kit disclosed by the invention is used for carrying out quantitative detection on the NT-proBNP and detecting whole blood, blood serum and blood plasma samples, can provide reference for diagnosis of cardiovascular and cerebrovascular diseases and can be widely applied to primary hospitals and clinics.

The invention discloses a kit for double-sandwich immunofluorescence quantitative detection of human anti-Mullerian hormone (AMH) on the basis of quantum dots and application thereof. The original kit contains an AMH protein standard substance, an ELISA plate coated with an AMH specific polyclonal antibody and a CdTe quantum dot labeled AMH monoclonal antibody. The detection antibody used in the kit is a CdTe quantum dot label for monoclonal antibodies, and can better remove background signals; the detection method is simple and convenient, and has high practicality; the detection result directly determined by a fluorescent ELIASA indicates that the emitted fluorescence has the advantages of narrow spectrum peak, weak autofluorescence and high sensitivity; the kit has the advantages of high fluorescence intensity and long stabilization time, and overcomes the actual states of low sensitivity and poor specificity in the traditional ELISA detection kit; and the kit can enhance the resolution, sensitivity and specificity of ovary reservation function detection.

The invention relates to a single-matrix luminescent material used for a light emitting diode (LED), which outputs strong light under the stimulation of the near ultraviolet, and a preparation method thereof. The single-matrix luminescent material belongs to the field of luminescent materials. The borophosphate white light fluorescent powder has a composition formula of KBa(1-x)Eu<2+>xBP2O8, wherein x is a molar percentage coefficient of EU, which is accounted relatively to Ba, and m is more than 0 and is less than 0.1. The preparation method for the fluorescent powder comprises the following steps of: accurately weighing the raw materials according to a chemical composition formula; after the raw materials are grinded and evenly mixed, firing for 1-4h under the reducing atmosphere at the temperature of 900-1000DEG C; and smashing and screening after cooling to obtain the single-matrix luminescent material. Ray of 400-620nm can be stimulated from the fluorescent powder under the ray of 300-400nm (especially 350-370nm). The near ultraviolet stimulated borophosphate white light fluorescent powder is suitable for a near ultraviolet LED chip and has the characteristics of wide stimulating range, high luminescence luminance, simple and convenient preparation method and the like.

The invention discloses a fluorescence immunochromatographic assay and kit for quantitatively detecting cardiac troponin T (cTnT). The fluorescence immunochromatographic assay for quantitatively detecting cTnT realizes fluorescence quantitative detection on the basis of optimizing various constituent parts of test paper by using excellent fluorescence characteristic of quantum dots and combining a bicolor marking technology and an immunochromatographic technology. Compared with the conventional colloidal gold immunochromatographic assay, the fluorescence immunochromatographic assay disclosed by the invention has the advantages of good marking stability, low non-specificity, high sensitivity, wide linear range and quantifying accuracy. The fluorescence immunochromatographic kit disclosed by the invention is used for carrying out quantitative detection on the cTnT and detecting whole blood, blood serum and blood plasma samples and is suitable for different levels of hospitals and particularly good for wide popularization in primary hospitals and clinics.

The invention relates to ultraviolet and near ultraviolet excited phosphor powder used for white light LEDs and a method for preparing the phosphor powder. The formula of the phosphor powder is A3D2O5X2:Mx. In the formula, A is one or more than one of Mg, Ca, Sr and Ba; D is one or more than one of B, Al and Ga; X is one or two of Cl and F; M is one or two of Eu and Ce; x is more than or equal to 0.001 and less than or equal to 0.10. Hydrates, oxides or corresponding salts of the structural formula are used as raw materials and are calcinated for two to five hours at 1100 to 1300 DEG C in reducing atmosphere, and are cooled, thus preparing the ultraviolet and near ultraviolet excited phosphor powder used for white light LEDs. The phosphor powder is excited within the range from 200nm to 450nm; the emission wavelength ranges from 400nm to 700nm; the phosphor powder emits blue light, green light or white light, and can be used in ultraviolet and near ultraviolet excited white light LED devices.

The invention relates to a single-matrix white fluorescent powder, a manufacturing method thereof and a light emitting device manufactured thereby. The chemical formula of the involved fluorescent powder is Ba(3-m-n-a)AaLu2-bRbSi3O12:mEu2+,nMn2+. The method comprises the following steps of: mixing and uniformly grinding all raw materials; roasting the mixture in reducing atmosphere at a high temperature; and performing post-processing to obtain the fluorescent powder. The fluorescent power has the characteristics of high chemical stability, super-wide excitation waveband, adjustable emission wavelength as required, high luminous intensity and the like and has the advantages of simple method, no pollution and low cost. A white LED and a warm tone light source can be manufactured by using ultraviolet light or a ultraviolet LED chip and the fluorescent powder of the invention.

The invention relates to a novel high-scattering quantum dot fluorescent powder and a preparation method thereof. The preparation method comprises the following steps: mixing a water-soluble quantum dot with a certain concentration of the inorganic saline solution or a nano-oxide ultrasonically dispersed in the water, stirring, performing ultrasound wave, stirring, performing spray drying on the mixed solution under a certain temperature to obtain the novel fluorescent powder by taking the inorganic salt or the nano-oxide assembly as a matrix and taking a fluorescent quantum dot as a luminescence center. The fluorescent powder has excellent optical performances of the quantum dot, such as wide and continuous distribution of the excitation spectrum, narrow and symmetrical emission spectrum, adjustable color, saturated color and high photochemical stability and the like; the matrix material has a protective effect on the embedded quantum dot so that the fluorescent powder has a high scattering property. The rare earth resource is not used so that the sustainable development of the resource can be realized. The spray drying method is suitable for the industrial production and the produced high-scattering quantum dot fluorescent powder can be used for designing a high-quality illuminating and displaying device.

The invention discloses a doped system of silicate green fluorescent powder and a preparation method of the doped system of the silicate green fluorescent powder, and belongs to the technical field of luminescent materials. The chemical formula of the silicate green fluorescent powder is , wherein0<=x<=0.25, 0<y<=0.02 and 0<z<=0.1.. The method includes the specific steps that according to the stoichiometric ratio of all the elements in the chemical formula, barium salt, lithium salt, silica, europium oxide, erbium oxide and a moderate amount of surfactant are weighed; a precipitating agent solution is prepared; the europium oxide and the erbium oxide are dissolved with concentrated acid, and water bath processing is performed after a moderate amount of deionized water is added; then the barium salt, the lithium salt, the silica and the surfactant are added and stirred continuously, the precipitating agent is dripped in, the PH is adjusted to be larger than or equal to 7, and the mixture is continuously stirred for 1-4 hours; drying is directly performed, and a precursor is obtained; the precursor is placed in an atmosphere furnace with reducing atmosphere and calcined at 1000-1300 DEG C for 1-7 hours, and the needed fluorescent powder is obtained. The green fluorescent powder used for LEDs is high in luminescence intensity, good in stability and color rendering performance and applicable to exciting near ultraviolet radiation InGaN tube cores.

The invention discloses a fluorescence immunochromatographic assay and kit for quantitative detection of cardiac troponin I (cTnI). The fluorescence immunochromatographic assay for quantitative detection of the cTnI realizes fluorescent quantitative detection by utilizing excellent fluorescent properties of quantum dots and combining a bicolour marking technology and an immunochromatographic assay on the basis of optimizing each component of a test strip. Compared with the common collaurum immunochromatographic assay, the fluorescence immunochromatographic assay has the advantages of good mark stability, low nonspecificity, high sensitivity, wide linear range and accuracy in quantification. The kit disclosed by the invention is used for carrying out quantification detection on the cTnI, can be used for detecting whole blood, blood serum and plasma samples simultaneously, and is applied to different levels of hospitals and is particularly favored to be widely popularized to primary hospitals and clinics.

The invention discloses LED nitride fluorescent powder and a preparation method thereof. The chemical structural formula of the LED nitride fluorescent powder is LaXbZcNd: rR, wherein L is at least one of Ca, Sr and Ba; X is at least one of B, Al, Ga, In and Tl, wherein Al is necessary; Z is at least one of C, Si and Ge, wherein Si is necessary; R is at least one of La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb and Lu, wherein Eu is necessary; and (a + r): b: c: d is equal to 1: 1: 1: 3. The preparation method is as follows: weighing raw materials according to the composition of the chemical formula of the fluorescent powder and the stoichiometric ratio, adding an activator, uniformly mixing in a glove box, sealing, then adopting the normal-pressure high-temperature solid-state method for carrying out multiple roasting under the protection atmosphere, and carrying out post-treatment for obtaining the LED nitride fluorescent powder. The luminescent material is characterized by good chemical stability, high luminescence efficiency and the like, and the manufacturing method is simple, pollution-free and low in cost.

The invention relates to orange long-afterglow fluorescent powder and a preparation method thereof. The chemical formula of the fluorescent powder is Sr3-x-y-zMzAl2O5Cl2: Eu2+x, Dy3+y, wherein M is one or two of Ba, Ca and Mg; x, y and z are molar fractions; x is more than 0.0001 and less than or equal to 0.10; y is more than or equal to 0.0002 and less than or equal to 0.20; and z is more than or equal to 0 and less than or equal to 0.30. The preparation method comprises the following steps of: selecting oxide, hydroxide or corresponding salt in the structural formula as raw materials, mixing and grinding the raw materials, roasting the mixture for 2 to 5 hours at the temperature of between 1,200 and 1,350 DEG C under the reducing atmosphere of CO or H2, and naturally cooling and grinding the roasted product to obtain the orange long-afterglow fluorescent powder. After an excitation source is removed under the excitation of wavelength of 300 to 420 nanometers, the fluorescent powder has remarkable orange long-afterglow property, and human eyes can observe the orange long afterglow for over 1 hour in a darkroom. The orange long-afterglow fluorescent powder can be used for display marks or cautions at special places such as dark environment and the like. The long-afterglow fluorescent powder has the advantages of stable performance, low raw material cost, no pollution and simple preparation.

An alkaline halogen silicate fluorescent powder and its production are disclosed. The general formula is 2(Ca1-x-0.5z-0.5nSrx)0.mCa(FyCl1-y)2.SiO2:zEu.nMn; n=0, x is not greater than 0.45 or not less than 0; y is not greater than 0.1 or not less than 0.001, m is not greater than 1.7 or not less than 0.8, z is not greater than 0.18 or not less than 0.003; when n is not greater than 0.30 or greater than 0, x is not greater than 0.45 or not less than 0, y is not greater than 0.1 or not less than 0, m is not greater than 1.7 or not less than 0.8, z is not greater than 0.18 or not less than 0.003. The process is carried out by weighing materials proportionally, mixing and grinding for oxides and salts in elements, sintering at 500-700 deg. C for 1-4 hrs under air atmosphere, sintering at 700-1000 deg. C for 1-7 hrs under reducing atmosphere, cooling, crushing, screening, washing by alcohol and water and drying. It has strong absorbing performance between 250-470 nm wavelength, transmitting main peak is located between 505-605 nm. It has adjusting wavelength and can be excited effectively by violet light and blue light LED chip.

The invention belongs to the technical field of rare-earth light-emitting materials, relates to emission peak-adjustable phosphate fluorescent powder for a white-light LED (Light-Emitting Diode) and a preparation method thereof. Fluorescent powder for the white-light LED, which is stable in chemical property, high in light-emitting performance, high in physical phase purity and adjustable in the emission peak from green light to red light when being excited by near ultraviolet light, purple light and blue light and can be applied to the white-light LED excited by using a blue-light LED chip. The chemical components of the fluorescent powder can be shown as a chemical formula, namely, Ca9(1-x-y)-La(PO4)7:xEu<2+>,yMn<2+>, wherein x is more than or equal to 0.002 and less than or equal to 0.2, and y is more than or equal 0.002 and less than or equal to 0.2. The fluorescent powder can be used for exciting white light together with blue fluorescent powder BaMgAl10O17:xEu<2+>. An encapsulated device can reach a white-light area with low color temperature, warm tone (CCT is less than or equal 5,000K), high color rendering index (CRI, RA is more than or equal to 90) and a color coordinate being up to CIE1931. The preparation method is simple and easy to operate, contributes to saving energy and time, and has extremely good application prospect in the field of solid illumination.

The invention discloses a fluorescence immunochromatographic assay and kit for quantitative detection of acute myocardial infarction marker-creatine kinase isoenzyme (CK-MB). The fluorescence immunochromatographic assay for quantitative detection of the CK-MB realizes fluorescent quantitative detection by utilizing excellent fluorescent properties of quantum dots and combining a bicolour marking technology and an immunochromatographic assay on the basis of optimizing each component of a test strip. Compared with the common collaurum immunochromatographic assay, the fluorescence immunochromatographic assay has the advantages of good mark stability, low nonspecificity, high sensitivity, wide linear range and accuracy in quantification. The kit disclosed by the invention is used for carrying out quantification detection on the CK-MB, is suitable for detection of whole blood, blood serum and plasma samples, can provide a reference for cardiovascular and cerebrovascular disease diagnosis, and is widely applied to primary hospitals and clinics.

The invention discloses ultraviolet excited or near ultraviolet excited borate fluorescent powder and a preparation method thereof. A structural formula of the borate fluorescent powder is Ba(2-x-z)Sr(z)Ca(1-y)(BO3)2:xEu<2+>, yMn<2+>, wherein x, y and z are respectively mol percentages of the Eu<2+>, the Mn<2+> and the Sr<2+> in a compound; x is not less than 0 and not more than 0.15; y is not less than 0 and not more than 0.15; z is not less than 0 and not more than 1.5, and the values of x and y are zero simultaneously. The fluorescent powder disclosed by the invention has the advantages of no sulfur, stable performance, wider excitation spectrum, excitation range of 300-430 nm, transmission wavelength of 400-700 nm and suitability for excitation of ultraviolet excited and near ultraviolet LEDs (Light Emitting Diode); the light color of the fluorescent powder disclosed by the invention is adjustable and can be continuously converted from green light to red light according to needs; and the preparation method disclosed by the invention has the advantages of simplicity, feasibility, easiness for operation, easiness for production, no pollution and low cost.

The invention relates to blue fluorescent powder for a near ultraviolet LED and belongs to technology for preparing rare-earth fluorescent powder; the blue fluorescent powder has a chemical formula of Ca1-xMgSi2O6:xEu<2+>, x is more than 0 and less than 0.2; the technology comprises the following specific steps: according to the stoichiometric ratio of the chemical formula, calcium salt, magnesium salt, silicic acid, europia and proper amount of precipitator, surfactant and fluxing agent are weighed; the europia is dissolved through concentrated acid, is added with proper amount of deionized water, is subjected to water bath treatment, is added with the calcium salt, the magnesium salt and the surfactant, is stirred and is added with the precipitator for several times; the PH value of the solution is regulated to be more than or equal to 7 through ammonia; the solution is continuously stirred for 0.5 to 4 hours, is kept stand or is subjected to centrifugal precipitation, suction filtering, washing and drying to obtain a precursor; and the precursor and the weighed fluxing agent are evenly mixed, are positioned in a muffle furnace with the protection of reducing atmosphere and are calcined to obtain the needed fluorescent powder. The fluorescent powder completes adulteration and once calcination synthesis when the precursor is subjected to thermal decomposition, has good luminous intensity, stability, color rendering and granularity and is applicable to being used as the blue fluorescent powder of LED activated by InGaN tube core of near infrared radiation (350-410nm).