Fluorescence immunochromatographic assay and kit for quantitative detection of creatine kinase isoenzyme (CK-MB)

A technology of fluorescence immunochromatography and creatine kinase, which is applied in the field of medical testing, can solve the problems of expensive instruments, narrow linear range, and low sensitivity of creatine kinase isoenzyme detection, and achieve the effect of improving sensitivity and detection sensitivity
CN102520173AActive Publication Date: 2012-06-27SHENZHEN KANGMEI BIOTECH

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
SHENZHEN KANGMEI BIOTECH
Publication Date
2012-06-27

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Abstract

The invention discloses a fluorescence immunochromatographic assay and kit for quantitative detection of acute myocardial infarction marker-creatine kinase isoenzyme (CK-MB). The fluorescence immunochromatographic assay for quantitative detection of the CK-MB realizes fluorescent quantitative detection by utilizing excellent fluorescent properties of quantum dots and combining a bicolour marking technology and an immunochromatographic assay on the basis of optimizing each component of a test strip. Compared with the common collaurum immunochromatographic assay, the fluorescence immunochromatographic assay has the advantages of good mark stability, low nonspecificity, high sensitivity, wide linear range and accuracy in quantification. The kit disclosed by the invention is used for carrying out quantification detection on the CK-MB, is suitable for detection of whole blood, blood serum and plasma samples, can provide a reference for cardiovascular and cerebrovascular disease diagnosis, and is widely applied to primary hospitals and clinics.
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Description

technical field

[0001] The invention relates to the field of medical testing, in particular to a fluorescent immunochromatographic method for quantitatively detecting acute myocardial infarction marker creatine kinase isoenzyme and a kit thereof. Background technique

[0002] At present, cardiovascular disease has become the largest potential killer of adults worldwide. In the United States alone, more than 70 million people suffer from heart disease, and about 6 million people go to the emergency room due to chest pain every year. Acute myocardial infarction ( The death toll of AMI) has exceeded 500,000. In my country, the prevalence, incidence and risk factors of cardiovascular diseases are on the rise. According to statistics in recent years, the mortality rate of cardiovascular disease accounts for 40% of the population deaths, which is higher than that of European and American countries, and belongs to the country with high incidence of cardiovascular disease. Therefore...

Claims

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