274 results about "Medical testing" patented technology

This invention relates to the field of medical testing, specifically to a set of biomarkers, reagent kits, and their applications for diagnosing hypertension in children. This invention involves collecting tongue / intestinal samples from obese children with hypertension, obese children, and healthy individuals, performing metagenomic sequencing, and statistically analyzing the sequencing data using bioinformatics to identify disease-related tongue / intestinal flora. By integrating tongue / intestinal flora with disease information, a combination of flora biomarkers is obtained. A binary classification prediction model constructed using this combination can maximally detect hypertension in obese children.

The invention discloses a case misdiagnosis identification method and device and a storage medium, relates to the technical field of medical technology and machine learning, and discloses the steps that multi-source heterogeneous medical detection data of a to-be-identified case and a disease diagnosis result and a treatment strategy of a doctor on the to-be-identified case are acquired; based on the multi-source heterogeneous medical detection data, the disease diagnosis result and the treatment strategy, diagnosis and treatment path matching is conducted on a pre-constructed typical disease knowledge base, the corresponding diagnosis and treatment path deviation degree is obtained, and the typical disease knowledge base comprises multiple disease entries and reference diagnosis and treatment paths corresponding to the disease entries; and inputting the multi-source heterogeneous medical detection data, the disease diagnosis result, the treatment strategy and the diagnosis and treatment path deviation degree into a misdiagnosis recognition model, and performing misdiagnosis recognition on the to-be-recognized case based on the misdiagnosis recognition model to obtain a corresponding misdiagnosis recognition result, thereby solving the technical problem of low misdiagnosis recognition accuracy of the actual diagnosis and treatment path of the case in the prior art, and improving the accuracy of the misdiagnosis recognition. And the misdiagnosis identification accuracy is improved.

The invention discloses a Wright staining peripheral blood cell accurate identification system and method based on intelligent microscopic imaging and multi-modal fusion deep learning, belongs to the crossing field of medical examination and artificial intelligence, and is suitable for cell morphology analysis under a 10 * 40-time microscope. The core scheme comprises the following steps: standardized slide preparation and dyeing (the slide pushing angle is 25 + / -2 degrees, the pH is 6.8 + / -0.2, and color sensing dynamic regulation is performed); intelligent imaging (focusing formula and color normalization; the method comprises the following steps of (1) data processing, (2) data processing, (3) data processing, (4) data processing, (5) data processing, (6) data processing, (7) data processing, (8) data processing, (7) data processing, (8) data processing, (8) data processing, (8) data processing, (8) data processing, (8) data processing and (8) data processing.

The invention discloses a microbial culture device for medical examination, which comprises a cylinder body, a storage cavity is arranged at the upper end of the cylinder body, a cover body is arranged in the storage cavity, a through hole is formed in the cover body, a sealing cover is arranged at the through hole, a support frame and a lifting mechanism are arranged in the storage cavity, the support frame is used for placing a culture dish, and the lifting mechanism can push the culture dish out of the through hole. A liquid heating assembly is arranged at the bottom of the barrel, a first water channel is formed in the side wall of the storage cavity, a second water channel is formed in the cover, the liquid heating assembly communicates with one end of the first water channel, the other end of the first water channel communicates with one end of the second water channel, and the other end of the second water channel communicates with the heating assembly. The supporting frame, the lifting mechanism and the liquid heating assembly are all electrically connected to the control panel. The culture dishes on the supporting section frames extend out of the through holes with smaller openings through the lifting mechanisms, so that the heat loss can be reduced under the condition of water bath heating, and the temperature balance is ensured.

The invention belongs to the technical field of medical detection, and particularly relates to a marker for smoke disease diagnosis and application thereof. The invention discloses a marker for smoke disease diagnosis. The marker for smoke disease diagnosis is miRNA (micro Ribonucleic Acid); the miRNA is hsa-miR-4433a-5p, and the nucleotide sequence of the miRNA is as shown in SEQ ID NO. 1 (sequence identifier number 1). Experiments prove that the expression level of hsa-miR-4433a-5p in smoke disease patients is obviously higher than that of hsa-miR-4433a-5p in healthy people, and hsa-miR-4433a-5p can be used as a marker for smoke disease diagnosis. Meanwhile, the marker for smoke disease diagnosis is applied to preparation of the kit, the content of hsa-miR-4433a-5p in serum can be detected through a real-time fluorescent quantitative PCR technology, and the kit has the advantages of being high in sensitivity and accuracy and wide in application prospect.

The application discloses a clinical medical examination knowledge base construction and application method, device, equipment and medium, relates to the computer technical field, and includes: converting the collected clinical medical data into corresponding dense vectors based on a preset large language model to obtain a target clinical medical examination knowledge base; performing a configuration operation of a dialogue retrieval mode on the target clinical medical examination knowledge base, and after the configuration is completed, performing vector conversion on a received natural language sentence to be replied based on the preset large language model to obtain a corresponding question vector; by calculating the cosine similarity between the question vector and each dense vector in the target clinical medical examination knowledge base, the most relevant target vector to the question vector is determined; and based on the preset large language model and the target vector, a corresponding target natural language reply sentence is generated to reply to the natural language sentence to be replied. In this way, the retrieval efficiency can be effectively improved, and the convenience of retrieval is further improved.

The invention relates to the technical field of medical systems, in particular to an intelligent diagnosis auxiliary system based on informatization planning, which comprehensively collects inspection operation parameters and patient physique information and covers data in multiple aspects from inspection process details to patient individual physique characteristics. The data are mapped to a test method-interference factor relation network through a knowledge graph, the influence of test operation interference and patient physique interference on diagnosis can be comprehensively analyzed, the influence condition of interference parameters is quantified by adopting a natural constant power formula in test process anomaly analysis and physique-to-diagnosis disease anomaly influence analysis, and the diagnosis accuracy is improved. The non-linear quantification mode better accords with the actual relation between interference and influence in a medical examination operation scene, the influence degree of the examination process and the patient physique on diagnosis can be more accurately evaluated, and then a more reliable basis is provided for diagnosis.

The invention discloses a physical examination report interpretation method and device based on knowledge distillation. The method relates to the technical field of artificial intelligence, and comprises the following steps: obtaining a to-be-interpreted target physical examination report from a target queue; performing standardization processing on data in the target physical examination report through a classification model in a first container instance to obtain a medical examination data set with examination items as categories; performing abnormal index identification on the medical examination data set to obtain abnormal index data, and processing the medical examination data set through a medical entity identification model in a second container instance to obtain a medical entity set, and processing the medical entity set and the abnormal index data through an interpretation model in a third container instance to obtain an interpretation result. According to the method and the device, the problem of relatively low efficiency of interpreting the physical examination report due to the fact that the physical examination report is interpreted depending on manual professional knowledge in related technologies is solved.

The utility model belongs to the technical field of medical examination experiment instruments, and particularly relates to a test tube oscillator. Aiming at the problem that the existing test tube oscillator is tedious to fix and adjust, the oscillator provided by the utility model comprises an oscillator main body, an oscillation disc, a sliding rod, a pressing plate, a first elastic piece and a locking assembly, the oscillation disc is connected with the output end of the oscillator body, the two sliding rods are arranged on the two sides of the oscillation disc at the upper end of the oscillator body and provided with lock holes, the pressing plate and the locking assembly are longitudinally and slidably connected with the sliding rods, the first elastic piece is fixedly connected between the pressing plate and the locking assembly, and the locking assembly can be locked with the lock holes. When the test tube is fixed, through simple operations such as unlocking, lifting and pressing, the test tube is fixed by utilizing pressure generated by compression of the first elastic piece. The test tube fixing device is convenient to operate, high in error-tolerant rate and capable of quickly fixing test tubes with different heights; fixation is stable and reliable, and test tube loosening is avoided; the application range is wide, diversified requirements of medical examination can be met, and medical examination efficiency and result accuracy are effectively improved.

1. Name of the product in this design: Medical Detection Data Acquisition Device. 2. Purpose of this design: For collecting medical test samples. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The invention discloses a method for measuring the pressure in the heart cavity of a mouse, and relates to the technical field of experimental animal medical detection, and the method comprises the following steps: cutting an incision of about 1cm in the neck of the mouse; placing two sutures below the common carotid artery, and ligating the common carotid artery by using the suture at the distal end; the other section of suture line is placed in the middle of the right common carotid artery, the carotid artery is lifted up, the blood filling condition is observed, an opening is formed in the blood vessel, a pressure volume catheter is inserted, and meanwhile the suture line at the telecentric end is slightly pulled backwards to prevent bleeding; the pressure volume catheter is inserted into the left ventricle through the right common carotid artery, and the left ventricle pressure maximum rising rate and the left ventricle pressure maximum falling rate are collected. By means of the carotid artery approach, serious trauma caused by thoracotomy can be prevented, and the cardiac physiology can be possibly affected by the operation. Therefore, the carotid artery approach is more suitable for a long-time pressure collection experiment.

This disclosure belongs to the field of medical testing technology, and specifically relates to a classification, diagnostic, and prediction method, system, and electronic device for congenital neurodevelopmental disorders. Addressing the clinical diagnostic challenges of congenital neurodevelopmental disorders, this disclosure establishes for the first time a classification, diagnostic, and prediction method for congenital neurodevelopmental disorders based on whole-genome methylation signatures and customized SVM machine learning. This method achieves one-stop differential diagnosis across multiple mechanisms and diseases, filling a gap in existing technologies and providing a novel and efficient solution for the accurate diagnosis of congenital neurodevelopmental disorders.

The utility model relates to the field of oscillation devices, in particular to an oscillation device for clinical medical examination, which is used for oscillating a test tube and comprises a base, a lifting component for controlling the test tube to oscillate up and down is fixedly mounted at the top of the base, and a moving component for controlling the test tube to oscillate transversely is fixedly mounted on the lifting component. The moving assembly is fixedly provided with a driving assembly used for controlling the test tube to swing and oscillate, and the test tube is detachably fixed on the driving assembly through a clamping assembly. The sample test tube is convenient to take and place, the operation is simple, the use is convenient and fast, and the device is suitable for popularization and application.

The invention relates to the technical field of robots, and discloses a precise pressure control type medical examination pipettor gun head cleaning robot. The pipette tip is installed in the tip isolation shell, at the moment, the water level is located at the position of a first liquid level indicator, the robot automatic cleaning barrel is rotated to enable the tip isolation shell to be horizontally placed, then the robot automatic cleaning barrel is rotated to enable the pipette tip to be vertically upward, and at the moment, the tip isolation shell is full of cleaning liquid; a first switch is turned on, waste liquid in a pipettor gun head is transferred into a robot automatic cleaning barrel, waste liquid in a gun head isolation shell is transferred into the pipettor gun head under the siphoning effect, then the water level is supplemented to a second liquid level indicator, cleaning liquid starts to enter the gun head isolation shell at the moment, and when the cleaning liquid is supplemented, the robot automatic cleaning barrel is opened. And the water level is lowered to a third liquid level indicator, meanwhile, a first switch and a robot waste liquid water pump are turned on, waste liquid is discharged, and efficient cleaning of the pipette tip is achieved through repeated cleaning.

The invention relates to an artificial intelligence recognition system and application thereof in fungal morphology diagnosis, and relates to the technical field of medical examination and artificial intelligence crossing. The artificial intelligence recognition system deeply fuses an immunofluorescence technology and artificial intelligence, can be used for clearly distinguishing dead / viable thalli, performs image recognition, segmentation and feature extraction through the artificial intelligence system, and further performs comprehensive diagnosis in combination with clinical data.

The application provides a sample injection assembly and a capillary adapter, wherein the sample injection needle assembly has a sample injection needle body and a sample injection needle extending from a head end of the sample injection needle body; the capillary adapter has a first end and a second end and a through hole penetrating through the first end and the second end, the first end has a butt joint groove adapted to the head end of the sample injection needle, and the through hole is used for clamping the capillary at least at one end adjacent to the bottom of the butt joint groove. In this way, the butt joint of the capillary and the sample injection needle assembly is realized when the capillary adapter is butted with the sample injection needle assembly, the pressure borne by the capillary is reduced, the capillary is prevented from being broken, and after the capillary adapter is butted with the sample injection needle, the contact between the sample and air when the sample injection needle sucks the sample in the capillary can be isolated, so that the quality of the sample sucked by the sample injection needle is improved, and the measurement accuracy is improved.

The invention relates to the technical field of computer vision and intelligent medical examination, in particular to an animal pathogenic microorganism target image detection model construction system which comprises a sample collection module used for controlling digital microscopic imaging equipment to collect an original microscopic image matrix containing target microorganisms; the ideal reference construction module is used for constructing an ideal reference light field image matrix; the knowledge parameterization injection module is used for generating a theoretical simulation state image matrix, a biological factor tensor for controlling geometric deformation and a flaking factor tensor for controlling pixel intensity attenuation; the double-track difference module is used for generating a real light field residual matrix and a theoretical simulation residual matrix; the coupling judgment and model construction module is used for calculating the Euclidean distance of the feature vectors of the two residual matrixes; according to the method, rapid and accurate inversion from real observation to theoretical parameters is realized, and the efficiency of model construction and iteration is greatly improved.

This invention relates to an alanine aminotransferase (ALT) detection reagent and its preparation method, belonging to the field of medical testing. The ALT detection reagent comprises nanobodies AC1 and AT1 binding to different ALT binding sites. Nanobodies AC1 are biotinylated and immobilized on an avidin ELISA plate as a capture antibody, while nanobodies AT1 serve as the detection antibody. The ALT detection reagent and method prepared based on these nanobodies can meet the needs for rapid and accurate ALT detection.

This invention relates to the field of medical testing equipment, specifically to a pulsatile tinnitus detection device. The device includes a wearable body worn on the user's head, with symmetrically arranged sensing mechanisms on the wearable body for contacting specific areas of the user's skull to collect physiological signals. The wearable body also includes an intervention mechanism for simulating different hemodynamic states; the intervention mechanism includes an actuator and a compression head, the actuator driving the compression head to perform controllable compression and release. A control unit is also included, communicatively connected to the sensing and intervention mechanisms. The control unit controls the actions of the intervention mechanism, receives and analyzes the physiological signals collected by the sensing mechanisms, and correlates changes in physiological signals with the timing of compression and release actions to generate assessment information for determining the cause of pulsatile tinnitus, intraoperative effects, or postoperative recovery. This invention is used to objectively assess vascular recovery status, providing standardized and comparable assessment indicators for diagnosis and treatment.

The invention discloses a risk assessment system for difficulty in cross matching of blood, and relates to the technical field of clinical medical examination and blood transfusion management. The system comprises a data input module, a risk calculation module, a risk layering module and a result output and suggestion module. The data input module obtains key information of a patient, wherein the key information comprises an erythrocyte irregular antibody screening result, multiple myeloma diagnosis, hematology department medical history, age of more than or equal to 60 years, pregnancy-related disease state and blood type identification difficulty; the risk calculation module adopts a preset scoring algorithm to endow each factor with a weight and calculates a total risk score; the risk layering module divides the patients into three levels of low risk, medium risk and high risk; and the result output module provides differentiated clinical management paths corresponding to the risk levels. According to the method, early warning of difficulty in cross matching of blood is achieved through quantitative evaluation, blood transfusion process efficiency can be optimized, clinical risks can be reduced, and the method has good prediction performance (AUC = 0.819) and a high negative prediction value (93.7%).

This invention relates to the field of gene detection technology and discloses a high-throughput gene sequencing data multivariate quality control system, including a sample information management module, a sequencing data acquisition module, a multivariate quality control analysis module, a result output and traceability module, an equipment collaborative control module, and a data storage module. Each module communicates bidirectionally via a data bus to achieve real-time data transmission and interaction. This invention addresses the dual needs of clinical medical testing and forensic evidence identification, adapting to multiple application scenarios and solving the problem of single-scenario application in existing systems. It can simultaneously meet the quality control requirements for non-invasive prenatal testing, reproductive genetic testing, tumor gene testing, and forensic kinship identification, eliminating the need for multiple quality control systems, reducing equipment costs and operational complexity, and improving laboratory efficiency.

The invention relates to a preparation method and application of a suvortinib standard substance in human serum, and belongs to the field of medical examination. The standard substance is characterized by comprising the following three levels of suvaltinib solutions: a level 1: 10.00-50.00 [mu] g / L, a level 2: 10.00-50.00 [mu] g / L, and a level 3: 10.00-50.00 [mu] g / L; the level 2 is 450.00 to 750.00 [mu] g / L; the level is 3: 1200.00 to 2000.00 [mu] g / L; wherein the level 1 corresponds to the concentration range of the blood concentration trough of the suvortinib in the serum of a patient taking the medicine; the level 2 is an effective treatment blood concentration range; and the level 3 is the peak concentration range of the blood concentration. The standard substance can be used as a conventional detection limit and a reportable range of suvortinib in human serum. The standard substance has good uniformity, stability and interoperability, and can be applied to the fields of accuracy evaluation of blood concentration detection, detection result value traceability, performance evaluation of medical equipment, instrument calibration, research and development of medical equipment and the like.

The invention provides a physical examination information and data association analysis system based on a medical laboratory. The physical examination information and data association analysis system comprises a data acquisition unit, a data annotation and arrangement unit, an association analysis unit and a visual display unit. The invention further provides a medical laboratory-based physical examination information and data association analysis method, which comprises the following steps of: acquiring physical examination personnel information and a detection result, and storing the physical examination personnel information and the detection result as original physical examination data; labeling and sorting the original physical examination data to obtain to-be-analyzed physical examination data; establishing a correlation analysis model; calculating and analyzing correlation; and the system displays a correlation analysis result. According to the invention, personnel information and detection data are collected and stored in combination with an existing medical examination laboratory management system, and on the basis of monotonicity and discontinuity characteristics of the personnel information and detection data of physical examination people, visual correlation analysis of personnel and regional personnel information and a detection item system can be realized; and the information is converted into effective and valuable health management suggestions which are simple and easy to understand, so that diseases are prevented.

The invention belongs to the technical field of urine sampling devices for examination, and particularly relates to a sanitary urine sampling device for medical examination, which comprises a shell, the shell is hollow, a three-way valve is fixedly connected to the inner top wall of the shell, a communicating pipe is fixedly connected to the top wall of the shell, and the communicating pipe is communicated with the input end of the three-way valve. A placement shell is fixedly connected to the inner wall of one side of the shell, a middle cylinder is fixedly connected to the inner bottom wall of the placement shell, a detection assembly is arranged on the inner bottom wall of the placement shell, and a hollow part of the middle cylinder communicates with the detection assembly through an air pipe; through cooperation of the impeller torsion spring in the detection valve and the friction disc, the dripping state and the normal urination state are intelligently recognized, the flow direction of the three-way valve is automatically switched, automatic judgment and flow division of the urine discharge mode are achieved, and sampling opportunity errors or sample confusion caused by dependence on manual observation and judgment are avoided.

This invention belongs to the field of medical testing technology, specifically relating to a lateral flow test strip for ultra-high sensitivity detection of pathogens and its application. The lateral flow test strip provided by this invention uses polydopamine nanoparticles modified with bacterial antibodies as signal probes. Multiple detection lines are set on the NC membrane, and the detection lines are obtained by scribing with a bacterial antibody solution as ink. This invention replaces Au NPs in classic LFIAs with PDA NPs. Relying on the high extinction coefficient, affinity for bacteria, and stability of antibody binding of PDA NPs, a two-order-of-magnitude improvement in sensitivity is achieved when using LFIAs to detect bacteria. Simultaneously, utilizing the high extinction coefficient of PDA NPs, their signals can be identified and statistically analyzed by ImageJ software even when invisible to the naked eye. Combined with multiple test strips, this improves target capture efficiency, thereby achieving highly sensitive detection of pathogenic bacteria.

1. The name of the design product: enzyme label analyzer (DR-8000 series). 2. The use of the design product: a medical testing instrument for enzyme immunoassay. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view.

The utility model relates to the technical field of medical detection experiment appliances, and discloses a medical detection reagent dissolving device which comprises a dissolving barrel, a sealing cover is detachably connected to the upper end of the dissolving barrel, a motor is fixedly connected to the sealing cover, the output end of the motor penetrates through the sealing cover and is connected with a stirring frame, and a butt joint cover is fixedly connected to the lower end of the dissolving barrel. The lower end of the butt joint cover is detachably connected with a collecting barrel, a connecting column is connected in the collecting barrel in an up-down sliding mode, the upper end of the connecting column is fixedly connected with a plugging disc, the lower end of the connecting column is fixedly connected with a butt joint disc, the upper end of the collecting barrel is provided with a plurality of flow guide holes, the plugging disc is matched with the flow guide holes, and the inner wall of the dissolving barrel is provided with a conical surface and an arc-shaped surface. According to the utility model, the dead angle of the cavity is eliminated, the residual reagent hanging on the wall is reduced, the arc-shaped surface is matched with the annular stirring frame to form a vortex region, the uniformity of reagent dissolution is improved, and the problem of poor dissolution effect of the existing device is solved.

The invention discloses a kidney stone, hydronephrosis and pyosis detection system based on multi-scale feature fusion, and belongs to the technical field of medical detection, and the working process of the detection system comprises the following steps: S1, image data acquisition and preprocessing; s2, feature extraction and multi-scale feature fusion of the model; s3, classification decision and output layer design; and S4, model training and optimization. According to the system, from original DICOM image input to final diagnosis report generation, full-process automatic processing is achieved, manual intervention on feature engineering or intermediate steps is not needed, the system can generate a structured diagnosis report which comprises specific disease classification, confidence score and visual evidence heat map, the output format is normative, and the diagnosis report can be used for diagnosis. The method is easy to integrate with an existing image archiving and communication system of a hospital, and the model is clearly guided to pay attention to specific features related to ponding and infection in the learning process by introducing independent ponding and infection auxiliary discrimination branches and performing joint optimization with a main classification task.

The utility model discloses a medical detection sampling device which comprises a shell, a pressing ring is arranged on the upper side of the shell, a transmission rod is connected to the bottom of the pressing ring, the bottom end of the transmission rod penetrates through the shell and extends into the shell, and a convex frame is connected to the lower side of the transmission rod. According to the technical scheme, the shell is adopted as a main body, the sampling spoon capable of being pressed to stretch out and draw back is arranged in the shell, after an excrement sample is sampled through the sampling spoon, the sampling spoon can be retracted into the shell, and then the sealing assembly is connected with the shell, so that the odor of the excrement sample can be isolated, and the excrement sample can be conveniently taken out. Meanwhile, the sample can be prevented from being polluted, and the whole use is convenient and practical.