36 results about "Drugs trials" patented technology

The application discloses a kind of for drug test research room subject sign dynamic monitoring system, it is related to the field of drug test, solve the problem that drug test research room subject sign dynamic monitoring monitoring effect is poor, including data acquisition module: a plurality of physiological indexes are set to the physiological index monitoring of subject for characteristic test drug, obtain physiological index acquisition data, sign analysis module: according to physiological index acquisition data, sign index analysis is carried out to characteristic drug subject, according to the type division of subject is carried out to analysis result, obtains subject type division data, symptom analysis module: the typical symptom coincidence degree analysis is carried out to normal subject, according to analysis result, obtain typical symptom similarity coefficient, monitoring feedback module: according to subject type division data and typical symptom similarity coefficient, monitoring result feedback is carried out to characteristic drug subject, the accuracy and pertinence of subject sign dynamic monitoring process can be improved by the application.

The present application belongs to the field of AD drug test using rats, and particularly relates to a method for screening AD rat model and a method for evaluating recovery of AD rats after taking drugs, the screening method comprising the following steps: conducting sugar water and hot water drinking test on known normal healthy rats and AD rats to be tested; if the AD rats to be tested significantly decrease water drinking times in S area compared with normal healthy rats, and significantly increase water drinking times in C area, the AD rats to be tested are AD rats, the method for evaluating recovery comprises the following steps: conducting sugar water and hot water drinking test on AD rats continuously taking drugs for several days, if the AD rats gradually increase water drinking times in S area with increasing days, and gradually decrease water drinking times in C area, it is indicated that the AD rats recover after taking drugs, the method of the present application can simply, quickly and painlessly screen qualified AD rats, and can evaluate recovery of AD rats after taking drugs by using a low-cost method, thereby effectively reducing development cost and time of AD specific drugs.