66 results about "Drug test" patented technology

A portable drug sampling device for handheldly collecting a sample from exhaled breath of a subject for further sensor based analysis. The device comprising: a housing (406) comprising at least one inlet (407) and at least one outlet (408) for the exhaled breath to exit through, and a sampling membrane (302) arranged in the housing. A tubular element (40) having a mouthpiece section (401) for the subject to exhale into, and a saliva trap section comprising baffles (103) to create a non-straight gas flow path for letting aerosols pass through the tubular element. The sampling membrane (302) is arranged to collect the aerosols from the exhaled breath. The portable drug testing device further comprises a volume collecting element (208).

An automated system and method for passive testing of alcohol and drug abuse. The system enters a participant or subject into the system who is to be monitored during a probationary or other program for alcohol or drug abuse offenders. The system provides a drug testing home device or a drug testing kiosk device for use by the participant. The system enrolls the biometrics information of the participant into the computer system (e.g., finger print, voice, image, volatile compound organic gas level, and pH level). When the participant is to be tested in accordance with a testing schedule, the system validates these same biometrics of the participant, conducts the test, and then analyzes the test information for determining if the participant has been using alcohol or other drugs and should be subjected to a confirming urinalysis exam.

The metabolic processes involved in the formation of any glucose-based metabolite of a metabolic network are determined. A precursor molecule is labeled with a stable carbon (¹³C) isotope at specific positions. The label is allowed to distribute and rearrange in the system. Metabolites are recovered and analyzed against a control system to determine a set of metabolic pathway substrate fluxes caused by changes to the test system relative to the control system such as the addition of compound being tested as a potential drug.

The invention discloses an in-vitro individualized medicine test method for lung cancer and a culture medium, and belongs to the field of cell biology and pharmacology. The in-vitro individualized medicine test method and the culture medium have the advantages that the culture medium M can be applied to normal epithelial cells and primary tumor cells of human or mammals, accordingly, in-vitro culture systems for tumor cells and para-carcinoma cells of lung cancer patients can be established, and primary cells, with continuous passage and quick proliferation functions, of patient individuals can be obtained; the culture systems can be used for detecting the sensitivity and the safety of medicines or combination groups of the medicines, and accordingly stable, accurate and reliable lung cancer individualized treatment-medicine sensitivity test standard detection process systems can be established; individualized sensitive chemotherapy medicines or compositions screened by the aid of the lung cancer individualized treatment-medicine sensitivity test standard detection process systems can be combined with clinical medicine or relevant subjects, accordingly, clinical individualized treatment schemes can be formulated, and the in-vitro individualized medicine test method and the culture medium can ultimately serve for clinical application.

Systems, methods, and apparatus allow for capturing the results of drug tests using mobile devices. One or more implementations include apparatus that interface a mobile computing device with a drug test, while ensuring that an imaging device of the mobile computing device is optically aligned with a test display areas of the drug test. One or more additional implementations include a method for analyzing drug testing results. The method includes receiving and analyzing drug testing data, which includes an identification of a type drug testing apparatus being used at a remote testing device, and an image that visually represents a portion of a drug test. The method also includes analyzing the test results of the drug test based on the identification of the type drug testing apparatus.

A bio-nano-chip (BNC) technology that works in connection with non-invasive samples, such as saliva, cheek swab or urine samples that can be easily performed by non-specialists, such as security personnel and police officers is disclosed. The microfluidic system for drug testing includes an analyzer or reader having a housing containing a slot for receiving a cartridge, a drug testing cartridge, a processor having a user interface, an optical or energy sensing means, and a means for moving fluid.

A versatile drug testing device (a lateral flow diagnostic testing device) includes a flat transparent carrier with a top and a bottom with the carrier having a series of independent parallel grooves formed therein running from adjacent to the top to adjacent to the bottom of the carrier, each groove having a first opening and a second opening above the first opening therein adjacent to the bottom of the carrier, at least one drug test strip installed in one of said grooves with its absorbent pad contiguous to the openings and a cover layer attached to the carrier operable to sealing close each of said grooves whereby the bottom of the device can be immersed in a specimen of “urine”, “body fluid” or “other biological specimen” to wet the pad of the at least one test strip though the ingress of the specimen though the associated openings and the test results on the test strip can be easily viewed through the transparent carrier. Because of the unique construction the device will give accurate reading if temporarily immersed in the specimen or left in the specimen for an extended period of time, making it very user friendly.

The invention relates to a method for establishing a damp-heat diarrhea animal model. The method includes the steps of putting a Wistar rat in a metabolism cage and letting the rat freely drink hydromel; alternatively carrying out fasting, sufficient forage feeding, and lard gavage every other day for 10 days; filling a proper amount of liquor on the 10-15th days, and placing the rat in high temperature and humidity environment for 5 days; and injecting Escherichia coli into the abdominal cavity on the 16th day, and injecting again in 24 hours. By observing the general condition of the rat and detecting the blood, blood viscosity, blood biochemistry and serum cytokines, it is shown that the damp-heat diarrhea animal model is established successfully by the method. The animal model constructed by the invention has good reproducibility and stability, and can withstand the test of drug test, so as to provide an ideal animal model for developing new therapeutic drugs.

Described are three-dimensional, engineered, biological cancer models, methods of producing the same, and methods of identifying a therapeutic agent for cancer in an individual utilizing the three-dimensional, engineered, biological cancer models.

Described herein is a drug delivery system, which is based on a novel polymer namely hypromellose-graft-chitosan (HC), useful to deliver a drug to a patient in sustained and controlled release fashion. HC is highly water soluble across the pH range from 1.2 to 10, and has a high pH buffering capacity to provide a pH-stable environment for drug delivery. In addition, the drug delivery system provided herein exhibited a drug loading efficiency of over 90% in all drugs tested, which is 1-2 fold higher than the efficiency attainable by conventional chitosan, and achieved a 2-3 fold longer duration of sustained drug release.

A remote-controlled automated system for drug testing and screening. Systems and methods for the discovery of new pharmaceuticals according to their toxicity and/or efficacy, where the discovery process is guided by a computer assisted system and performed into a remote laboratory; additionally, a machine learning algorithm is configured to obtain the results.

A disposable cartridge can be used for biofluid sample collection, preparation, and mixing with reagents. After sample collection, the cartridge can be inserted into a reader for sample analysis. This system can be used for detecting and measuring analytes, such as drugs, in saliva for example. This is useful for point of test detection of drugs in applications such as workplace drug testing and driving under the influence of drugs testing.

The invention provides a simplified analysis method and system for pharmacokinetic parameters, and belongs to the technical field of pharmacokinetics. According to the method, when pharmacokinetics ofa single administration test of a clinical drug test is analyzed, values which are in a data set and are lower than the lower limit of a measurement method and cannot be measured are subjected to self-defined conversion, and important parameter results such as Cmax, Tmax, the average blood concentration value of each dose group in a test group at each planned blood sampling time point and the like are obtained; an operation result is merged into the original data set under the condition that the format of the original data set and other variable data in the data set are not influenced and changed, and a new data set is generated or directly covers the original data set. Statists can simply use the method provided by the invention in SAS software to quickly obtain the required operation result, and can directly carry out subsequent analysis and research work without spending a lot of time in importing, merging or sorting data sets among different software.

A novel method for testing human tissue in a testing system is more effective than conventional cell culture systems and functions by treating the human tissue slice system's samples with at least one compound and observing the effect on the human tissue slices resident therein, or cells, tissue samples or other derivatives from the testing process.

The invention belongs to the technical field of drug testing, and provides a prediction method and device for the sensitivity of a target drug, a terminal device and a storage medium. The method comprises the following steps: acquiring clinical factor information and single nucleotide polymorphism (SNP) site information of a user to be tested, wherein the SNP site information is the information ofa site, that may act with a target drug, in a gene of the user to be tested; extracting SNP information features according to the SNP site information, and extracting clinical factor features according to the clinical factor information; and according to the SNP information features and the clinical factor features, predicting the sensitivity of the to-be-tested user taking the target drug. According to the method, the information of the site, that may act with the target drug, in the gene of the user to be tested and the clinical factor information are taken as prediction information, and corresponding SNP information features and clinical factor features are extracted for prediction, so higher prediction accuracy is obtained in detection of generation of sensitivity when the to-be-tested user takes the target drug.

The invention discloses a multifunctional fixing rack for an experimental animal. The multifunctional fixing rack is characterized in that the upper end of a stand column is fixedly connected to a U-shaped rack (1) via a bolt or a nut; two arms of the U-shaped rack are provided with several or more than ten sets of holes; each set of holes is formed by a side through hole and a vertical screw hole, center lines of which are perpendicular; a telescopic rod (6) adaptive to an aperture is inserted into each side through hole; each vertical screw hole is connected with a bolt (7) with a rotary button; the lower end of each bolt has a contact with the telescopic rod; the other end of the telescopic rod is provided with a slot hole in a sleeved connection with a hook handle, one end of which is equipped with a slot hole via the bolt; the end part of each bolt is connected with a nut (10) with a rotary button; and the other end of the hook handle (9) is provided with a hook (8). The multifunctional fixing rack is especially suitable for surgery experiments, and also suitable for medical scientific researches and teaching experiments including physiological and pathological change observation tests of experiment animals, drug tests and biopsy tests.

The invention discloses a quick detection method for the drug susceptibility of coccidium of different species. The method comprises the following steps of constructing a real-time fluorescence quantification PCR analysis method for TaqMan of the to-be-detected coccidium of different species; collecting clinical test coccidium samples, and separating out coccidium oocysts; carrying out an anti-coccidium drug clinical test; obtaining results of drug susceptibility of the to-be-detected coccidium of different species by analyzing the composition and proportion change of sample coccidium populations before and after the drug test. By means of the quick detection method, the situation in a traditional method that it needs several months before the complicated step of separating a single coccidium is completed can be avoided, the drug susceptibility and the drug resistance test result of the coccidium of different species can be directly obtained in only several days, the working time, labor and material resources are greatly saved, and better prevention and control over clinical coccidiosis are facilitated.