An exemplary
system, method and computer-accessible medium for determining
resultant information about a portion(s) of a tissue(s), can include, for example, receiving initial information which is based on a particular
radiation that is returned from the portion(s), the particular
radiation can be is based solely on an interaction between the portion(s) and a near-
infrared radiation forwarded to the portion(s), and determining the
resultant information about the portion(s) of the tissue(s) based on the initial information. The near-
infrared radiation can be provided by a near-
infrared light optical arrangement that can include a diffusely reflected near-infrared light arrangement. A depth of a
lesion to be ablated can be determined by the near-infrared radiation based on the initial information. The initial information can include data corresponding to a reflectance spectrum(s) of the portion(s).