This invention discloses a GTR membrane, its preparation method, and its application, belonging to the field of biomedical materials technology, and solves the problem of insufficient
antibacterial effect of existing GTR membranes. The method includes the following steps: uniformly dispersing BaTiO3 in a
Tris buffer solution; dissolving
dopamine hydrochloride powder in the
reaction system; stirring evenly; centrifuging to collect the precipitate; cleaning and
drying to obtain PDA@BaTiO3 nanoparticles; adding the PDA@BaTiO3 nanoparticles to a silver
ammonia solution; stirring at
room temperature; centrifuging to collect the precipitate; cleaning and
drying to obtain Ag@PDA@BaTiO3 particles; uniformly dispersing the Ag@PDA@BaTiO3 particles in a hexafluoroisopropanol solution of L-
polylactic acid;
electrospinning the
reaction system to obtain a
fiber membrane; and sequentially subjecting the membrane to ventilation, high-temperature annealing, and natural cooling to
room temperature to obtain the GTR membrane. The GTR membrane provided by this invention possesses both piezoelectric and photothermal effects, exhibits rapid sterilization and long-lasting
antibacterial activity, and has a simple preparation process.