87 results about "Tobacco use" patented technology

Embodiments of the invention provide methods for the transdermal delivery of therapeutic agents for the treatment of addictive cravings e.g., nicotine compounds for the treatment of nicotine cravings from tobacco use. An embodiment of a method for such delivery comprises positioning at least one electrode assembly in electrical communication with a patient's skin. The assembly includes a solution comprising a therapeutic agent which passively diffuses into the skin. A dose of agent is delivered from the assembly into the skin during a first period using a first current having a characteristic e.g., polarity and magnitude, to repel the agent out of the assembly. During a second period, a second current having a characteristic to attract the agent is used to retain the agent in the assembly such that delivery of agent into skin is minimized. A dose of agent may be delivered on demand by an input from the patient.

A composition for nasal administration comprising varenicline or its pharmaceutically acceptable salt and at least one excipient. The invention also provides a composition for buccal administration comprising varenicline or its pharmaceutically acceptable salt and at least one excipient to form a solid dosage form, wherein the solid dosage form disintegrates in an oral cavity at body temperature and may adhere to body tissue of the oral cavity; a composition for pulmonary administration comprising varenicline or its pharmaceutically acceptable salt and at least one excipient; and, a method for reducing nicotine addiction, aiding in the cessation of, or lessening of tobacco use in a subject.

The invention discloses a method for producing a spice for cigarettes by using waste tobacco as a raw material. The method comprises the following steps: adding 5 to 10 percent of amino acid by weight into 5 to 15 percent of the waste tobacco by weight generated during threshing and re-drying, then adding 60 to 95 percent of solvent by weight into the mixture, placing the mixture into a normal-pressure reaction kettle, stirring the mixture evenly, adjusting the pH to be between 8.0 and 9.5, and then making the mixture react for 3 to 4 hours at a constant temperature of between 90 and 105 DEG C under the conditions of stirring, heating and condensing reflux; and after the reaction is ended, quickly filtering the hot reaction product, and decompressing and condensing the filtrate to obtain a spice product for the cigarettes, wherein the solvent comprises water, propylene glycol and ethylene glycol, and the ratio of the propylene glycol to the ethylene glycol to the water is 1-6:1-6-1. The spice for the cigarettes has the characteristics of obvious flue-cured tobacco note, fresh fragrance and sweetness, fragrance and sweetness of paste, fragrance of licorice, roasting fragrance, acid fragrance, and the like. When the spice is added into a tobacco product, the spice can enhance and enrich cigarette fragrance, fineness and softness, mellowness, smoke, and the like, and can promote internal quality of the cigarettes.

The invention discloses a rose blended tobacco baking and flavoring method which comprises the following steps of: installing the harvested fresh tobacco on rods, loading the tobacco into a bulk curing barn, separately placing roses in 4-8 ventilated containers during the tobacco flue-curing color curing period, evenly distributing the containers at 3-5 cm away from tobacco, baking the tobacco for 120-140 h, wherein the weight ratio of rose to tobacco is 1:3500. The invention develops a new method, plant rose and tobacco are baked in the same oven, tobacco cells absorb volatile fragrant substances of the rose through breathing under the action of temperature and humidity, so that the purposes of enriching tobacco fragrance, covering miscellaneous smell, improving smoking taste, increasing tobacco sweetness and reducing the dry sensation of smoke are achieve, and the demand of top-grade high-end cigarette brands for high-quality raw material is satisfied. Plant fragrance raw material rose is added before tobacco is industrially used, so that the fragrant ingredients of the rose can be well cured in tobacco. Not only is the use level of rose essence reduced in industrial use, but also the safety of tobacco use is also increased.

A substantially pure fraction of at least one cannabinoid is added to smokable or smokeless tobacco products to reduce the harm associated with tobacco use. The harm to be reduced includes irritation and carcinogenicity of tobacco. In a preferred embodiment a whole plant cannabis extract is mixed directly with the tobacco during the curing or manufacturing process. For cigarette applications the cannabinoids may be inserted into a cigarette filter, and / or paper. In other embodiments the cannabinoids are purified.

The invention discloses concrete flavouring for tobacco and a preparation method and application thereof, belonging to the technical field of additive for tobacco. In the invention, waste tobacco used as raw material is sequentially fermented with rhodococcus, bacillus pumilus and bacillus subtilis to reduce nicotine in the waste tobacco and convert ferulic acid in the tobacco into incense ingredients such as 4-guaethol and vanillin; after fermentation is finished, the conventional biochemical technology is utilized to extract the incense ingredients from the waste tobacco for preparing concrete flavouring. The concrete flavouring obtained by invention contains the following main incense ingredients with higher contents: benzyl alcohol, solanone, vanillin, BETA-damascenone, dihydroactinidiolide, megastigmatrienone, duvatriene diglycol and neophytadiene. Results of an aromatic flavouring smoke panel test show that the concrete flavouring has obvious effects of increasing tobacco aroma,smoothing alcohol and smoke, reducing irritation, covering impurity gas and improving smoking taste of cigarettes.

A processing method for increasing low-grade tobacco use value includes the steps: moistening a tobacco group composed of low-grade tobacco to enable the water content to be 18-22%; storing for 1-24h, and entering a lining feeder to enable the tobacco water content to be 28-36%; using a burley tobacco curing machine to dry the tobacco under the conditions that the temperature is 70-1100 DEG C and the process flow is 1600kg / h to enable the water content of tobacco in a cooling area to be 4-7%, and entering a resurgence area to enable the tobacco water content to be 10-14%; entering a surface material feeder to enable the tobacco water content to be 18.5-21.5% after surface material feeding, storing for 1-4h, and shredding, wherein the tobacco water content is 17.5-20.5%; and drying the shredded tobacco through a sheet cut-tobacco dryer to enable the tobacco water content to be 12.5-13.5% after drying of cut tobacco. By means of the processing method, the use ratio of low-grade tobacco in third-grade and fourth-grade cigarettes can be evidently increased to be 8-20%, and cost of formula raw materials can be remarkably lowered.

Disclosed are a carbon heating low-temperature cigarette compound atomization agent, preparing method and application of the same. The raw materials of the compound atomization agent comprise the following parts by weight: 1 part of 1,2- propylene glycol, 10-20 parts of glycerin, 0.01-0.4 part of firming agent, 0.002-0.006 part of sodium benzoate, 0.01-0.1 part of tobacco-used flavoring and 10-20 parts of water. The compound atomization agent is in a semi-solidity colloid with certain viscidity, enables the cut tobacco to absorb more atomization agent and flavoring compensation substances, avoids infiltration defect of the cigarette appearance, overcomes the defect that common tobacco cannot effervesce, aerify and release smoke before being ignited. In addition, the compound atomization agent has the characteristics of not volatilizing under the condition of 25-60 DEG C, instead emitting tobacco smell after tobacco ignition so as to perfectly simulate smoke. The smoke releasing continuity is good, the standstill time is proper, better smoke releasing effect is obtained and good sensory quality is kept at the same time.

The invention relates to a technique of a fertilizer for cultivating a cured tobacco, in particular to a fertilizer special for a multi-element tobacco and a preparation method thereof. The special fertilizer comprises the following components in portion by weight: 12.6 to 13.0 portions of urea, 9.8 to 10.2 portions of diamine phosphate, 39.8 to 40.2 portions of potassium sulfate, 18.0 to 22.0 portions of bone powder, 6.8 to 7.2 portions of humic acid, 1.8 to 2.2 portions of rare earth, 3.5 to 3.9 portions of medium element, and 0.8 to 1.2 portions of microelement. The fertilizer special for the multi-element tobacco uses the rear earth and the humic acid as main bodies, belongs to nutrient fertilizers, and can greatly improve the integral level of a tobacco field, improve the yield and the quality of crops, stimulate the growth of the crops, improve the disease resistance of the crops, prolong the release cycle of the fertilizer, reduce the fertilizer loss, improve the stress resistance of the crops, and provide a large amount of organic matters for soil to play a role of improving the soil.

The invention discloses a method and application for extracting tobacco use spice from corn cobs, which belong to the field of preparation and application of tobacco spice in the cigarette technology. The method comprises the following steps: (1) crushing the corn cobs into a pressure vessel and holding the corn cobs in the pressure vessel at a room temperature and under 3MP for 3 to 15 minutes; (2) setting the proportion of the corn cobs: 50 to 95 percent ethanol equal to 1: (5-10), setting the extracting temperature at 75 to 90 DEG C and the extracting time 0.5 to 4 hours; (3) concentrating the mixture to the density of 1.0317; and (4) refrigerating the mixture at 2 DEG C below zero to 2 DEG C and obtaining the corn cob extract after filtering. The corn cob extract is added into tobacco shreds for perfuming according to a proportion of 0.06 to 0.1 percent; or the corn cob extract is added into a tobacco use spice recipe according to a proportion of 0.02 to 2 percent and then the perfuming is carried out. The method is simple and practical and is easily carried out; and the method has high extracting yield. The corn cob extract has the effects of softening the tobacco gas, refining the tobacco flavor and promoting flavor emission.

This invention relates generally to formulations, compositions, aerosols and kits used to provide habitual tobacco users with products, methods and apparatus to reduce and eventually terminate their dependence on nicotine containing products. More specifically, the invention relates to a nicotine-based medicament and dosage forms thereof formulated in such a way as to effectively reduce or eliminate the sensations of craving associated with addictive nicotine use.

The invention discloses a tobacco composition in flue-cured type cigarettes. The tobacco composition comprises the following tobaccos in parts by weight: 2-3 parts of third-grade tobacco in the central Hubei Enshi with the sugar-nicotine ratio of 8-12, 1-2 parts of first-grade tobacco in the north Yunnan Pu'er with the sugar-nicotine ratio of 8-12, 1-2 parts of third-grade tobacco in the central Gangxi Hezhou with the sugar-nicotine ratio of 8-12, and 1-2 parts of second-grade tobacco in the central Guizhou Tongren with the sugar-nicotine ratio of 8-12. The tobacco composition can be used for completely replacing the Canada tobacco used in the existing first-grade and second-grade cigarettes, thereby effectively relieving the dependence of the cigarette product development on the imported tobaccos, improving the utilization efficiency of the domestic tobaccos, and ensuring the sustainable development capability of cigarette products. The first-grade and second-grade cigarettes prepared by using the tobacco composition provided by the invention to replace the Canada tobacco used in the existing first-grade and second-grade cigarettes can still satisfy the style characteristic requirements of the first-grade and second-grade cigarettes.

The invention discloses a mint-doped tobacco baking and blending method, which is characterized in that: fresh tobaccos are collected, woven into rods and then placed into an intensive baking room in accordance with requirements of the three-stage tobacco baking process, mint is separately arranged in 4-8 breathable containers and are uniformly distributed for 3-5cm away from tobaccos at the bottom, and baking is carried out for 120-140 hours; and the weight ratio of the mint leaves to the tobaccos is 1 to 7000. The method is unique, the mint and tobaccos are baked in one furnace, tobacco cells can absorb volatile fragrant substances of the mint due to effects of the temperature and humidity, the tobacco aroma can be enriched, the mixed smell can be masked, the smoking flavor can be improved, the dryness of flue gas can be reduced, and the flue gas can be made to be cool and moist. Meanwhile, the aroma of the mint is added into the tobaccos prior to industrial use, the fragrant components of the mint can be well cured in the tobaccos, the consumption of mint essence in the industrial use can be reduced, and the safety of tobacco use can be improved.

The invention relates to the field of tobacco, in particular to a tobacco processing method of sucking flavor components in tobacco using fog media and a tobacco sucking device. The method comprises the following steps: under a heating condition, the flavor components in tobacco products are sucked using the fog media. The tobacco processing method of sucking the flavor components in the tobacco using the fog media has the advantages that passive smoking can not produced; all kinds of hazardous substances produced by cleavage reaction caused by burning and bar components which are most harmful to human bodies are not included in water vapor produced when the method is used; and in the whole using process, open fire is not needed, and therefore using safety is improved to a great extent. Meanwhile, a considerable amount of nicotine can be provided for the human bodies when incombustible-type tobacco products and corresponding devices are heated, and physical feelings similar to traditional cigarette flavor are also provided or the human bodies, and therefore the tobacco is mellow, fine and smooth after entering a mouth, and is rich in gradation.

A chewing gum composition including a water insoluble base portion; a water soluble portion; and a therapeutically effective amount of varenicline or its pharmaceutical acceptable salt thereof. A method for reducing nicotine addiction and aiding in the cessation or lessening of tobacco use in an individual by administering to an oral cavity of an individual a chewing gum composition including an effective amount of varenicline or its pharmaceutical acceptable salt thereof; and chewing the gum composition to cause the varenicline or its pharmaceutical acceptable salt thereof to be released from the chewing gum composition into the oral cavity of the individual. A method of manufacturing a chewing gum composition.

A method for the prevention of dementia is provided including the steps of testing, in a client, for a dementia risk factors (including those related to brain tissue, atrial fibrillation, hypercoaguable state, LDL cholesterol, carotid artery evaluation, tobacco use, hypertension, and inflammation evaluation), determining a score for each of the risk factors tested, wherein each score is based on a continuous scale from a low number to a high number, wherein a low number corresponds to a relatively low likelihood of dementia risk and a high number corresponds to a relatively low likelihood of dementia risk, applying all of the scores obtained to an equation that yields a resulting value proportional to an overall risk of dementia, and providing dementia risk reduction advice to the client to lower the scores for each of the components.

Embodiments can provide a wearable device for nicotine cessation behavioral support, comprising a top surface; a first surface; a second surface; an underside surface; a communication device; one or more buttons; an internal storage medium; and a power supply; wherein the one or more buttons are configured to log a NRT use event to the internal storage medium when depressed and subsequently released within a predetermined timeframe; wherein the one or more buttons are configured to log a tobacco use event to the internal storage medium when depressed and released at a time longer than the predetermined timeframe; wherein the one or more buttons, when depressed, are configured to log a craving event to the internal storage medium, wherein an intensity of the craving event is determined by a time duration between depression and release of the one or more buttons.

The invention discloses a preparation method of tobacco maltose caramel flavor. Maltose, which is used as a raw material, undergoes a reaction in an autoclave; and then the reaction product undergoes fractional separation. After the separation, tobacco-use quality and style features of each ingredient are analyzed and studied. On this basis, all separated ingredients are compounded and recombined so as to obtain the maltose caramel flavor with different tobacco-use effects. The maltose caramel is I-type caramel pigment, thus avoiding safety risks. In addition, the unique style of the maltose caramel is naturally harmonious with a cigarette product. The product of the invention has an extremely good application effect of enhancing style features of a cigarette product.

The invention discloses a method for determining the contents of benzene and benzene-series substances in tobacco-use triacetin. The method comprises the steps of internal standard extract preparation, standard working solution preparation, sample solution preparation, gas chromatography-mass spectrometry analysis, determination result calculation, and the like. The invention adopts an internal standard method in quantitation. An optimized detection method has the advantage of simple and accurate operation, such that errors brought by pretreatments and instrument precision are effectively reduced. With the adopted chromatographic conditions, separations of chromatographic peaks of 6 target objects and internal standards are good, and the chromatographic peaks have good linear correlation. A detection limit is 0.01-0.02mug / g, an average relative standard deviation is 2.02-7.01%, and a standard addition recovery rate is 89.0-108.5%. The method has the advantages of high sensitivity, good repeatability, high recovery rate, and the like. The method has good practicality.

The invention discloses an electronic tobacco and a method for detecting the quality guarantee period of the electronic tobacco. The electronic tobacco comprises a power battery as well as a microcontroller and a vaporizer which are respectively connected with the power battery, wherein the microcontroller is provided with a first timing module, a comparison module and a control module; the first timing module is used for timing; the comparison module is used for comparing the timing time of the first timing module with the preset timing time; the control module is used for controlling the power battery of the electronic tobacco to stop supplying power to the vaporizer when timing time is greater than or equal to the preset timing time according to the comparison result of the comparison module; the preset timing time is equal to the quality guarantee period of the electronic tobacco and is set and stored by the microcontroller. The method has the beneficial effects that when the quality guarantee period of the electronic tobacco is over, the electronic tobacco does not operate, and a user is reminded, so that the taste and safety of the electronic tobacco used by the user are ensured.

The invention discloses low-tar mixed type expanded tobacco and application of the low-tar mixed type expanded tobacco in low-tar cigarettes. The low-tar mixed type expanded tobacco is formed by mixing, by weight, 35 percent to 45 percent of burley tobacco, 25 percent to 45 percent of yellow sun-cured tobacco and 15 percent to 35 percent of aromatic tobacco through a carbon dioxide expansion technology. According to the application of the low-tar mixed type expanded tobacco in the low-tar cigarettes, the low-tar mixed type expanded tobacco accounting for five percent to 15 percent of the total weight of the tobacco used in tobacco curing is doped in the production process of cigarette products, and rolling is carried out. The mixed type formula expanded tobacco is low in tar, the filling value is good, the tobacco is added to the cigarettes, the aim of reducing the tar and harm is achieved, and the fragrance of the cigarettes can be richer.

Pharmaceutical compositions are disclosed for the treatment of alcohol or cocaine dependence or addiction, alcohol dependence or addiction, reduction of alcohol withdrawal symptoms or aiding in the cessation or lessening of tobacco use or substance abuse or other behavioral dependencies. The pharmaceutical compositions are comprised of a therapeutically effective combination of a nicotinic receptor partial agonist and an alpha2delta ligand and a pharmaceutically acceptable carrier. The method of using these compounds is also disclosed.

The described invention provides a system and method for clinical outcome tracking and analysis. The clinical outcome tracking and analysis comprises sorting, outcome tracking, quality of life metrics, toxicity to therapy and cost of care. The system and method includes receiving one or more parameters. Exemplary parameters for sorting include sex, age, ethnicity, comorbidities, tobacco use, source of insurance, medical record number, primary care physician, referring physician, hospital, approved service vendors, disease-specific clinical molecular phenotype, therapy intent, stage of therapy, biomarkers, and cost of care.

The invention relates to a flexible tobacco conveying system of AGVs (Automatic Guided Vehicle). The flexible tobacco conveying system comprises a controller, a plurality of tobacco storage cabinets,a plurality of cigarette making machines, a plurality of AGVs and an AGV runway, wherein the plurality of AGVs are used for loading transfer boxes, and the AGV runway is used for the AGVs to run; at least one tobacco outlet is formed in each tobacco storage cabinet, a tobacco outlet conveyor is arranged at each tobacco outlet, a lifting conveyor is arranged on the output end of each tobacco outletconveyor, and a feed funnel is installed on the output end of each lifting conveyor; and a feed area and a discharge area are respectively formed in both ends of the AGV runway, feed stations of which the number is consistent with that of the feed funnels are formed in the feed area, the feed funnels are located above the corresponding feed stations, tobaccos can be conveyed to the transfer boxeswhich are driven to pass through the lower parts of the AGVs by the AGVs by the feed funnels, discharge funnels of which the number is consistent with that of the cigarette making machines are arranged in the discharge area, and a discharge opening of the lower end of each discharge funnel is connected with a feed opening of the corresponding cigarette making machine. According to the flexible tobacco conveying system, cross-district tobacco transfer can be flexibly realized, the tobacco use measurement of a single cigarette making machine can be realized, and the maintenance cost is low.

The invention relates to an ascorbate peroxidase gene in a lycium chinense miller cytoplasm and an application thereof. The ascorbate peroxidase gene has a nucleotide sequence shown in a sequence of SEQ ID No.1; the ascorbate peroxidase gene LmAPX in the lycium chinense miller cytoplasm is cloned by extracting total RNA (Ribonucleic Acid) of fresh lycium chinense miller leaves through a homology-based cloning strategy and a 3'-RACE (Rapid Amplification of Cdna (complementary deoxyribonucleic acid) Ends) technology to obtain a complete coding gene sequence 753bp. An escherichia coli expression vector Pet28a-LmAPX is constructed, the enzyme activity of the cloned ascorbate peroxidase gene LmAPX code in the lycium chinense miller cytoplasm is identified by using an escherichia coli heterologous expression system, and a recombinant protein has higher activity for substrate ascorbic acid (AsA) and H2O2. Meanwhile, a binary plant expression vector pCAMBIA2300-LmAPX is constructed and is transplanted into an agrobacterium C58 cell by using an electroporation method, and the agrobacterium C58 cell is used for transforming a tobacco to obtain a transgenic tobacco used for subsequent adversity stress research.

The invention discloses a fermentation method for removing peculiar smell of tobacco leaves of sun-cured tobacco and application of the tobacco leaves in heated cigarettes. The fermentation method comprises the steps of airing, modulating, sorting to-be-bundled tobacco leaves of sun-cured tobacco according to types, uniformly spraying edible white spirit of 50 degrees or above on the surfaces of petioles, or directly dipping the petioles in the edible white spirit of 50 degrees or above, bundling and wrapping, and storing in a clean, odorless and shady inner room for 40 days or above. In allusion to the flavor quality requirements of heated cigarettes on the tobacco leaves of the sun-cured tobacco raw material, by adopting the fermentation method disclosed by the invention, the peculiar smell and mould of the tobacco leaves generated by the traditional fermentation method can be effectively removed, the tobacco leaves are naturally and sufficiently fermented, bright in color and pure in tobacco flavor, and the sensory quality of the sun-cured tobacco used as raw material tobacco for the heated cigarettes is remarkably improved while the flavor characteristic of the sun-cured tobacco is ensured.