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97 results about "Membrane transport" patented technology

In cellular biology, membrane transport refers to the collection of mechanisms that regulate the passage of solutes such as ions and small molecules through biological membranes, which are lipid bilayers that contain proteins embedded in them. The regulation of passage through the membrane is due to selective membrane permeability - a characteristic of biological membranes which allows them to separate substances of distinct chemical nature. In other words, they can be permeable to certain substances but not to others.

Clamping type residual membrane recovering machine

The invention relates to a clamping type residual membrane recovering machine, belonging to the field of agricultural machinery. The machine comprises a traction device, a drive system, a residual membrane box, an earth wheel and a residual membrane recovering device, wherein the residual membrane recovering device consists of a clamping type residual membrane picking wheel, a sprocket rake type residual membrane transporting device, a baseboard, a membrane removing wheel and a contour wheel; the clamping type residual membrane picking wheel consists of a chain wheel, four rows of clamps, a push rod, a clamp bracket, a restoring spring, a baffle block and a cam wheel; the lower end of each clamp is provided with a shifting fork; a plurality of rows of rack bars are arranged on the sprocket rake type residual membrane transporting device; the residual membrane recovering device is arranged at the back side of the residual membrane box in a hinging way; a clamping type residual membranepicking mechanism is arranged at the lower end of the residual membrane recovering device; a contour earth wheel is arranged at the back side of the lower end of the residual membrane recovering device; the baseboard is arranged at the lower side of the sprocket rake type residual membrane transporting device; and the membrane removing wheel is arranged at the upper end of the residual membrane recovering device. The clamping type residual membrane recovering machine is fast in work speed, can be used for recovering small pieces of the residual membrane, is high in residual membrane recovering rate, and can be used for meeting the residual membrane recovering requirement.
Owner:SHIHEZI UNIVERSITY

Method for building BCRP (breast cancer resistance proteins) mediated medicine transport models for research on 3D (three-dimensional) organs of small intestines and application

The invention discloses a method for building medicine transport models for research on BCRP (breast cancer resistance proteins) mediation for 3D (three-dimensional) organs of the small intestines of mice. The method includes separating crypts from the small intestines of the mice by means of digestion, suspending the crypts in matrigel and then joining the crypts with cell culture plates and promoting differentiation of the crypts by the aid of ADMEM/F12 media with Respondin-1, m-noggin and m-EGF cell differentiation growth factors to form the 3D organs; carrying out morphologic observation and detecting the expression level of BCRP genes and proteins to verify the feasibility of model theories; carrying out research on the trans-membrane transport activity of BCRP in the 3D organs by the aid of fluorescent substrates Hoechst 33342 of the BCRP and inhibitors Ko143 or YHO-13177 of the fluorescent substrates by co-incubation processes. The method has the advantages that the medicine trans-cell-membrane transport in-vitro models for the research on the BCRP mediation for the 3D organs of the small intestines of the mice are built for the first time, and the method for building the models is easy and convenient to implement and high in detection efficiency and speed and can be widely applied to screening BCRP substrates and inhibitors in an in-vitro manner.
Owner:EAST CHINA NORMAL UNIV

Method for preparing nano magnetic microballoons and anticancer oral preparation prepared using the method

The invention discloses a method for preparing nanometer magnetic microspheres and an anticancer oral preparation prepared by utilizing the method. The method comprises the process steps of: a, material preparation, in which a carrier material, a framework material, a drug and a solvent are prepared; b, the preparation; c, the stability and drying; and d, the crushing and preparation and so on. The method takes beta-cyclodextrin as the framework material and includes the carrier material (a nanometer magnetic biomaterial) and drug combination and so on. The drug-loaded nanometer magnetic microspheres can quickly reach appointed focus target positions, penetrate target cell membranes to enter cells, realize the trans-membrane transport of target macromolecules, achieve the effects of targeted release and slow / controlled release, improve the drug concentration in target cells, and inhibit the gene expression and amplification of the target cells to ensure that the target cells are degenerated to necrotize or apoptosize; at the same time, the microspheres strengthen the killing activity of T cells and NK cells and the phagotrophic ability of macrophages to the target cells, improve the immunity of organisms, and achieve the effects of multiple treatment and multi-drug resistance reverse.
Owner:黄云清

Intelligent lettering mechanism of belt-film transporting system for producing large transfusion soft bag

The present invention discloses an intelligent printing mechanism for a membrane transport system for large transfusion soft bag production, which comprises a rack, at least one set of thermal transfer printing intelligent marking system that can print large transfusion soft bag lettering, and one set of membrane transport system. The thermal transfer printing intelligent marking system comprises a control panel and at least a printed letter; the membrane transport system is composed of a membrane transport device and a membrane tensioning device. The thermal transfer printing intelligent marking system of the invention can input and print graphics and text, print real-time variables, such as the production date, the batch number, and the validity period, and also can print bar codes; the membrane transport system can make the bag membrane pass under the print head of the intelligent marking system at a normal printing speed required by thermal transfer printing intelligent marking system, so as to solve the problems that the prior art requires batch number replacement for heating, and is low in production efficiency and poor in printing quality, thereby the production efficiency and product quality is improved.
Owner:HUNAN CHINASUN PHARMA MASCH CO LTD
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