1087results about How to "Enhance phagocytosis" patented technology

The present invention discloses a fruit and vegetable probiotic tablet and a preparation method thereof. The fruit and vegetable probiotic tablet uses probiotic powders such as lactobacillus plantarum powder as the main raw material, and the preparation method scientifically mixes modified dietary fibers, fruit and vegetable powder, oligosaccharides, plant extracts, protein powder, tea leaf extracts and traditional Chinese medicine extracts and etc., thus improves the content of soluble celluloses which are of real significance for probiotic flora, enhances the physiological activity of celluloses, thereby increases the species of intestinal probiotic flora as well as significantly enhances the colonization ability and time of endogenous and exogenous probiotics in the human intestinal tracts, effectively inhibits the growth and reproduction of harmful intestinal bacteria, especially gram-negative bacteria, and fully regulates the composition of the intestinal probiotic flora. The prepared fruit and vegetable probiotic tablet has a high biological activity, a long human intestinal colonization time, and a significant weight loss effect, and is suitable for a wide range of people.

A vegetative additive for the mixed feed used to culture quatic animals is proportionally prepared from adhesive, allicin, and 8 Chinese-medicinal materials including dandelion herb, phellodendron bark, scutellaria root, liquorice root, etc. Its advantage is high effect to kill bacteria and virus and promote the development of immune organs.

The invention relates to a composition for enhancing immunity and a preparation method of the composition for enhancing the immunity. The composition comprises the following raw materials: cordyceps sinensis powder, marine fish oligopeptide, corn oligopeptides, wheat oligopeptides, American ginseng extract, ganoderma extract, medlar extract and ganoderma spore powder. According to the preparation method, the cordyceps sinensis powder and three short peptide materials with biological activity are combined, and are supplemented with the plant extract capable of improving the immunity, therefore, the effect of enhancing the immunity can be achieved.

The present invention relates to a kind of Chinese medicine composition for preventing bird flu of chicken and duck. The Chinese medicine composition is prepared with forsythia 90-110 weight portions, honeysuckle 40-60 weight portions, northern isatis root 25-45 weight portions, skullcap root 40-60 weight portions, basket fern rhizome 40-60 weight portions and astragalus root 70-90 weight portions. The Chinese medicine composition is for fowls to take orally, has obvious bird flu preventing effect and is safe and convenient.

The invention discloses a concentrated feed containing Chinese herbal medicine for growing-finishing pig. The concentrated feed comprises soybean meal, fish meal, rapeseed meal, stone powder, calcium hydrogen phosphate, soybean oil, and premix; the following Chinese herbal medicine components are added into the concentrated feed: rhizoma atractylodis, processed fleece-flower root, gentian, tangerine peel, white peony root, parched medicated leaven, parched hawthorn, parched malt, medulla tetrapanacis, semen cuscutae, stir-fried betelnut, radix astragali, scutellaria, rhubarb powder, etc. The feed can improve the immunity, disease resistance, and stress resistance of growing-finishing pigs; the feed has improved quality, can enhance the appetite of the animals, and promote the digestion and the absorption; and the utilization rate of the feed is increased, and the breeding cost is reduced. The feed also has blood circulation invigorating, stomach-strengthening, parasite-expelling, and rapid fattening functions.

The invention discloses a health food for improving immunity and a preparation method thereof. The health food is prepared from the following raw materials in part by weight: 1 to 3 parts of dendrobium officinale, 2 to 6 parts of American ginseng and 6 to 18 parts of Chinese wolfberry. Pharmacological experiments prove that: the health food has an obvious effect of promoting an immune system, canobviously improve a phagocytic index of macrophage of immunosuppressed mice and increase coefficients of immune organs in nonspecifc immune experiments, can improve the conversion rate of lymphocytes, improve the level of immunoglobulin IgG, IgA and IgM in serum of the immunosuppressed mice and assist in conditioning immunodeficiency disease, and diseases such as weakened immune system, low resistance and the like.

The invention discloses weight-losing probiotic tablets and a preparation method thereof. According to the weight-losing probiotic tablets and the preparation method thereof, probiotic powder such as lactobacillus plantarum is taken as a main raw material, and modified dietary fibres, fruit and vegetable powder, oligosaccharides, plant extract, protein powder, tea leaf extract, Chinese herb extracts and the like are scientifically compounded, thus increasing the content of soluble celluloses with real significance in probiotic groups, and enhancing the physiological activity of the celluloses, and then remarkably improving the planting capacity and the planting time of endogenous and exogenous probiotics in human intestinal tracts, effectively suppressing the growth and the reproduction of intestinal harmful bacteria, in particular, Gram negative bacteria, and adequately regulating the composition of the intestinal probiotic groups while increasing the types of the intestinal probiotic groups; the prepared weight-losing probiotic tablets are high in bioactivity, long in planting time in the human intestinal tracts, remarkable in weight-losing effect, and wide in the range of appropriate crowds.

Multicomponent vaccines are provided which aid in the prevention and treatment of staphylococcal infections and which include certain selected combinations of bacterial binding proteins or fragments thereof, or antibodies to those proteins or fragments. By careful selection of the proteins, fragments, or antibodies, a vaccine is provided that imparts protection against a broad spectrum of Staphylococcus and other bacterial strains and against proteins that are expressed at different stages of the logarithmic growth curve. In one embodiment of the invention, a composition is provided that includes a fibrinogen binding domain of a fibrinogen binding protein and a bacterial component such as ca capsular polysaccharide, and both active and passive vaccines based on these components are also provided, along with methods of treating infection using these compositions and vaccines.

The invention provides human binding molecules specifically binding to West Nile virus and having West Nile virus neutralizing activity, nucleic acid molecules encoding the human binding molecules, compositions comprising the human binding molecules and methods of identifying or producing the human binding molecules. The human binding molecules can be used in the diagnosis, post-exposure prophylaxis and / or treatment of a condition resulting from West Nile virus.

The invention provides laying hen compound biological feed additive, and belongs to the technical field of feed science and feed additives. The feed additive is compoundly prepared by feed grade fluvic acid, worm powder, fermented frass, an extractive compound preparation, a microecologic preparation and carriers by a certain ratio. Premix of the compound biological feed additive is used in the feed of a laying hen. Environment in the digestive tract of livestock and poultry can be regulated and controlled, intestinal flora balance in an organism can be regulated, the organism immunity can be improved, and the feed additive has the properties of being antimicrobial and anti-stress, and improving immunity and production. The feed additive is added into daily ration of the laying hen to improve the laying capacity and the immunity of the laying hen, improve the feed conversion rate, and then to reduce drug residue and improve egg quality. The compound biological feed additive is a safe and reliable and green environmental protection feed additive product, and the application prospect is good.

The present invention relates to tartarian buck wheat tea. It includes 1.5-3 kg of tartarian buck wheat, 1-2 kg of chrysanthemum flower, 1-2 kg of medlar, 0.5-1 kg of cassia seed and 0.05-0.2 kg of tartaria buck wheat extract extracted by CO2 supercritical extraction process. Its preparation method includes the following steps: selecting material, disinfecting, pulverizing, baking, mixing, uniformly stirring, drying, bagging and sterilizing to obtain the invented product which rickly contains biological active flavone and can be used for making health-care beverage with the functions of preventing and hypertension, hyperlipemia and hyperglycemia.

The invention discloses a beautifying and nursing essence and a preparation method thereof. The essence is prepared from an epidermis cell nutrient solution and contains a plurality of cell growth factors, amino acids and vitamins. The essence mainly comprises an epidermal growth factor, a fibroblast growth factor, collagen type I, a stem cell growth factor, a horn cell growth factor and amino acids and vitamins including gamma-aminobutyric acid, coenzyme Q, medical vitamin C, medical vitamin B5 and medical vitamin E. The preparation method for the essence comprises the following steps: acquisition of epidermis of umbilical cord tissue of a newborn; cell culture; collection of a cell nutrient solution; filtration sterilization; condensation of a volume; addition of active components; addition of glycerin and hyaluronic acid; etc. The beautifying and nursing essence provides a plurality of endogenous nutritional ingredients with physiological activity for the skin, can promote metabolism of epidermis cells and repair damaged cells, has a moisture retention effect and is applicable to skin beautifying and nursing.

The invention discloses medicinal steamed bread for treating diabetes. Every 100 grams of steamed bread contain 3-10 percent by weight of medicament which is prepared from the following raw materials in parts by weight: 10-6 parts of Chinese yam, 10-5 parts of gorgon euryale seed, 10-3 parts of fragrant solomonseal rhizome, 8-3 parts of common anemarrhena, 8-3 parts of Mongolian snakegourd root, 8-3 parts of sophora flower, 8-2 parts of sealwort, 8-2 parts of corn stigma, 6-2 parts of dwarf lilyturf root, 6-2 parts of asparagus, 6-2 parts of propolis, 6-1 parts of curcumin and 6-1 parts of mulberry leaf. The medicinal steamed bread can be used for relieving, improving, preventing and treating diabetes type I and diabetes type II, so that the aims of relieving, improving, preventing and treating with medicinal foods are achieved.

The invention is generally directed to methods and compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind a TREM2 protein, e.g., a mammalian TREM2 and / or human TREM2. The methods provided herein find use in preventing, reducing risk, or treating an individual having dementia, frontotemporal dementia, Alzheimer's disease, Nasu-Hakola disease, or multiple sclerosis.

The invention discloses a traditional Chinese medicine extract for preventing bird flu and a preparation method thereof. The traditional Chinese medicine extract contains honeysuckle, forsythia, Baikal skullcap root, radix isatidis, thick wood-fern rhizome, heartleaf houtluynia, radix astragali and Bupleurum and has the characteristics of obvious medical effect and safe and convenient use for preventing and curing the bird flu. The preparation method of the invention is that: a. the ingredients are respectively crushed into coarse powders; b. the coarse powders are added with solvent and the extracted liquid is collected; c. the obtained solution is concentrated; d. the clarifying agent is added, fully mixed and stewed; e. the sediments of the clarified liquid medicine are removed by an industrial centrifuge to obtain the liquid medicine that meets the standard. The healing effect of the preparation achieved due to using the preparation method of the invention is exact and the quality is reliable.

The invention provides a light fasting full nutrition formula brewing instant bar and a preparation method thereof. The formula can brew various components of instant nutrient nutrients according to the suggested configuration of the 'Chinese Dietary Guidelines', foods are diverse, and no preservatives, no sweeteners and no artificial pigments are added; the bar is prepared from, by weight, oil, aquatic eggs, dairy products, soybeans, nuts, cereal potatoes, dietary fibers, fruits and vegetables, nutritional strengthening components and the like, is convenient to eat, and is especially suitablefor meeting the full nutritional needs of a body during light fasting and fat reduction.

The invention discloses a Chinese medicinal herb nonreactor biological feed additive which comprises the following effective ingredients in parts by weight: 1-4 parts of astragalus membranaceus, 1-2 parts of semen cuscutae, 1-2 parts of herba epimedii, 1-3 parts of pericarpium citri reticulatae, 1-3 parts of scorched hawthorn fruit, 1-3 parts of fructus aurantii, 1-2 parts of liquorice root, 1-3 parts of isatis root, 1-2 parts of dandelion, 1-3 parts of cordate houttuynia, 1-2 parts of herba portulacae, 1-3 parts of honeysuckle, 1-3 parts of rhizoma atractylodis and 1-3 parts of compound microbial starters. The Chinese medicinal herb nonreactor biological feed additive has functions of resisting bacteria and diminishing inflammation, regulating qi-flowing and helping digestion, benefiting the spleen and invigorating the stomach, enhancing immunity and the like, plays a role of completely replacing antibiotics, does not generate drug resistance; various growth performances and indexes are remarkably improved after beasts and birds are fed with the Chinese medicinal herb nonreactor biological feed additive; the beasts and the birds produced after the beasts and the birds are fed with the Chinese medicinal herb nonreactor biological feed additive are green, safe and pollution-free.

The invention relates to an artificially cultured black termitornyces albuminosus berk heim entity and a culture method thereof. The method comprises the following steps: finely selecting wide collected black termitornyces albuminosus berk heim to obtain pure strains by a tissue and spore separation method; carrying out stock spawn preparation and mother seed and culture seed preparation; using cotton seed hulls, broad-leaved tree sawdust, various crop straws and forestry leftovers as major culture raw materials to be matched with additives of wheat bran, corn powder, rice bran and mineral elements as a culture medium; using artificial temperature, humidity, air and light illumination control and mushroom loosening measures for auxiliary effect under the condition of natural environment; and realizing the annual culture to obtain large-blade thick-stipe twisting black termitornyces albuminosus berk heim entities with light brown or dark brown to darkish brown pileus and stipe surfaces. The artificially cultured black termitornyces albuminosus berk heim has the advantages of tender flesh quality, crisp soft smooth and cooling effect and delicious taste. The weight of a fresh single blade is about 50 to 200g, the processing and the eating are convenient, and the artificially cultured black termitornyces albuminosus berk heim has higher eating and medicine values. The invention has the characteristics of low cost, easy realization and the like, and can be widely applied to the scaled annual culture of the black termitornyces albuminosus berk heim.

The invention discloses a whole molecule IgG antibody of a whole human-derived anti-CD47. The whole molecular IgG antibody contains a light chain variable region and a heavy chain variable region; the amino acid sequence of the light chain variable region is as shown in a SEQIDNO.3, or a conservative variant obtained by addition, deletion, replacement and modification on one or more amino acids of the sequence; the amino acid sequence of the heavy chain variable region is as shown in a SEQIDNO.4, or a conservative variant obtained by addition, deletion, replacement and modification on one or more amino acids of the sequence. The invention also discloses a DNA molecule, an expression vector, a host cell and the application of the whole molecular IgG antibody.

The invention relates to the technical field of antibody drugs, in particular to a humanized anti-CD47 monoclonal antibody and an application thereof. The humanized anti-CD47 monoclonal antibody provided by the invention can effectively inhibit tumor growth, dose-dependently block the binding of human SIRP alpha and human CD47, promote the phagocytosis effect of macrophages on tumor cells, preventthe tumor cells from evading a defense system of tumor immunity, and play an anti-tumor role; the monoclonal antibody can block the binding of the CD47 on the surfaces of the tumor cells and the SIRPalpha on the surfaces of the macrophages, block a ''do not eat me'' signal of the tumor cells, promote the recognition and uptake of the tumor cells by the macrophages, and promote the progress of phagocytizing the tumor cells; and the binding of the CD47 on the surfaces of the tumor cells and the SIRP alpha on the surfaces of the macrophages is a universal ''do not eat me''signal, and the CD47 can be used as a very promising target in the tumor immune system, and can play a powerful and effective role in human tumor treatment.

The invention relates to a feed additive for broiler chickens and a preparation method of the feed additive, belonging to the field of feed additives. The feed additive comprises the following materials based on parts by weight: 35-38 parts of chitosan, 35-38 parts of chitin, 12-15 parts of calcium amino acid chelate, 2-3 parts of zinc amino acid chelate, 2-3 parts of iron chitosan chelate, 1-2 parts of copper chitosan chelate and 5-7 parts of D-glucosamine hydrochloride. The feed additive is obtained by means of conventionally drying, mixing, crushing, sifting, physical blending and packaging the above materials. The feed additive for broiler chickens is applied after being mixed with the daily ration of animals, and the addition amount is 1.5% of the total amount of the daily ration. The use of the feed additive can effectively promote animal growth, enhance organism immunity and reduce fat content and cholesterol content of the broiler chickens, and the feed additive can partly or completely replace antibiotics in the daily ration.

The invention discloses an iron tailing far-infrared ceramic material and a preparation method thereof. The ceramic material is characterized by being prepared from the following components in percentage by weight: 35-75% of iron tailings, 1-9% of clay, 11-25% of silicon dioxide, 11-25% of calcium carbonate and 2-6% of aluminum oxide, wherein the sum of the percentage of the components is 100%; the iron tailing comprises the following main components: 30-35% of SiO2, 20-25% of Fe2O3, 10-15% of Al2O3, 10-15% of TiO2 and a small amount of CaO, Na2O and MgO, and the sum of percentage of the components is 100%; XRD shows that the main components of the ceramic material are anorthite, diopside and titanium sheet iron ore. According to the preparation method, the iron tailing, the clay, silicon dioxide, calcium carbonate and aluminum oxide are used as raw materials, and are subjected to ball-milling, screening, allocation, stirring, drying, mixing, dry pressing forming and sintering, thereby preparing the iron tailing far-infrared ceramic material.

The invention discloses an immune type protein powder solid beverage and a preparation method thereof and belongs to the field of nutritional foods. The solid beverage comprises the following components: 70-85 percent of concentrated whey protein powder, 3-8 percent of pea protein, 5-15 percent of wheat protolysate, 2-4 percent of phospholipid, 1-3 percent of an acerola cherry extract, 1-5 percent of edible essence, 0.5-1.5 percent of a yeast extract, 0.5-1.5 percent of gamma-aminobutyric acid, 0.5-1.5 percent of coconut milk powder, 0.3-0.8 percent of silicon dioxide and 0.1-0.3 percent of stevioside. The invention also discloses the preparation method of the solid beverage. The solid beverage disclosed by the invention fully meets the demands of the human body, is scientific in prescription design, reasonable in nutrition arrangement and different in taste according to different customers, and can meet the special demands of different people on taste; the solid beverage is mellow in taste, convenient to use, stable in quality, simple in preparation method, easy to operate, suitable for large-scale industrial production, free of sugar in the prescription and suitable for diabetics to eat.

The invention provides a Chinese herbal tea for preventing and treating flu and for preventing and treating cold and upper respiratory infection. The Chinese herbal tea is prepared by processing 13 herbal medicines including honeysuckle, fructus forsythia, chrysanthemum, folium mori, scutellaria baicalensis, folium isatidis, dandelion, houttuynia cordata, isatis root, cyrtomium fortune, astragalus mongholicus, poria cocos and liquorice. The formula of the Chinese herbal tea for preventing and treating the flu is formulated on the basis of traditional Chinese medicine, traditional Chinese internal medicine, traditional Chinese medicine and pharmacology, traditional tea art and clinical experience of traditional Chinese folk medicine recipes for clearing summer heat, relieving exterior syndrome and resolving dampness, treating fever and aversion to cold, headache and body fatigue, bad appetite, choking sensation in chest and sicchasia, dispelling the wind and relieving pain, dispelling mild wind and opening the inhibited lung-energy. The Chinese herbal tea has the functions of enhancing immunity, resisting microbes and bacteria and preventing flu, can be used for effectively preventing and treating rhinitis, sphagitis, pneumonia and other diseases caused by cold and upper respiratory infection. The Chinese herbal tea is convenient to take and good in prevention and treatment effect.

The invention relates to a Chinese traditional hypoglycemic medicine, in particular a thirty-ingredient hypoglycemic gelatin capsule, which is prepared from thirty ingredients, including red ginseng, astragali, ganoderma lucidum, magnolia vine fruit, kudzu root, radix salviae miltiorrhizae, hemlock parsley, symbranchoid eels, dodder, black sesame seed, radix rehmanniae, radix rehmanniae preparata, blackfungus and so on, through extraction.

The invention relates to Chinese herbal medicament oral liquid for treating chicken colibacillosis, which is a preparation prepared from the following raw materials in part by weight: Chinese pulsatilla root 4-6, golden thread root 2-4, baical skullcap root 2-4, amur corktree bark 1-3, ash bark 1-3, white paeony root 1-3, dark plum 1-3, medicine terminalia fruit 1-2, campanumaea pilosula 1-3, astragalus root 1-3 and liquoric root 1-2. The raw materials are crushed, mixed, boiled in water for extraction, the extract is packed and packaged, and the oral liquid of the invention is manufactured. The Chinese herbal medicament oral liquid has a remarkable treatment effect on chicken colibacillosis.

The subject invention concerns a novel polysaccharide. RR1 is an α-D-glucan polysaccharide composed of a (1→4) linked back bone and (1→6) linked branches, which has been isolated from a medicinal herb, Tinospora cordifolia. RR1 exhibits unique immune-stimulating properties, is non-cytotoxic, and non-proliferating to normal lymphocytes, as well as tumor cell lines. The subject invention also concerns compositions containing an RR1 compound and methods for modulating an immune response in a subject using RR1 compounds. The present invention also provides methods for the use of an RR1 compound in conjunction with an antigen to stimulate an immune response, the RR1 compound providing an adjuvant-like activity in the generation of a Th1-type immune response to the antigen.

The invention relates to a mactra veneriformis extract which is prepared by the following method of taking the soft body part of the mactra veneriformis as a material, washing and grinding the material, adding water for decoction, filtering, then obtaining water decoction extracting solution, centrifuging the water decoction extracting solution,collecting supernatant fluid, concentrating, cooling, then adding ethanol for precipitating, filtering, obtaining an ethanol precipitate, drying and then obtaining the mactra veneriformis extract; and deproteinizing the mactra veneriformis extract to obtain purified mactra veneriformis extract which has glycemia-reducing, immune adjusting and liver-protecting functions. The invention also discloses the applications of the mactra veneriformis extract on preparation of medicaments or health care products simultaneously.

Multicomponent vaccines are provided which aid in the prevention and treatment of staphylococcal infections and which include certain selected combinations of bacterial binding proteins or fragments thereof, or antibodies to those proteins or fragments. By careful selection of the proteins, fragments, or antibodies, a vaccine is provided that imparts protection against a broad spectrum of Staphylococcus and other bacterial strains and against proteins that are expressed at different stages of the logarithmic growth curve. In one embodiment of the invention, a composition is provided that includes a fibrinogen binding domain of a fibrinogen binding protein and a bacterial component such as a capsular polysaccharide, and both active and passive vaccines based on these components are also provided, along with methods of treating infection using these compositions and vaccines.

The invention relates to the field of fish medicine preparations, in particular to Sanhuang supper micropowder as well as a preparing method and applications thereof. The supper micropowder comprises in percentage by weight as follows: 25-35% of baical skullcap roots, 25-35% of amur cork tree bark, 25-35% of rhubarb and 5-10% of indigowoad leaves. The Sanhuang supper micropowder has effects of clearing heat, cooling blood, resisting viruses and detoxifying, plays powerful antibacterial, disinfection and antiviral roles in water bodies and pathogenic bacteria of aqueous animal (gills, body surfaces and the like) tissue and is particularly used for mainly treating bacterial enteritis caused by pseudomonas, vibrio, aeromonas hydrophila and Edwardsiella in the aqueous animals. Tests prove that the Sanhuang wall-breaking supper micropowder can improve and treat white excrement enteritis of penaeus vannamei boone and septicemia of Micropterus salmoides to a certain extent, can enhance the aeromonas hydrophlia infection resistance of the Micropterus salmoides and is a novel fish medicine for effectively protecting intestinal tracts and preventing bacterial enteritis in the aqueous animals, and the use amount can be significantly decreased by 2-3 times.