The invention provides a production process of a high-transparency glass bottle. The production process comprises the following steps: (1) weighing of the following raw materials: 75-88 parts of silica sand, 1.5-2.8 parts of lithium chinastone, 0.5-2.4 parts of mullite, 2.5-3.8 parts of dolomite, 0.5-3 parts of diopside, 2.8-5.5 parts of potash feldspar, 1.5-3.5 parts of borax, 1.2-2.6 parts of sodium carbonate, 0.05-0.2 part of cerium oxide and 0.01-0.12 parts of yttrium oxide; (2) mixing: ball milling; (3) high-temperature fusion: feeding the mixed powder into a smelting furnace, performingfusion at 1,450-1,480 DEG C, and keeping the temperature for 14-20 h to obtain a glass stock solution; (4) contour machining: after cooling to 1,380-1,400 DEG C, and performing blow-molding; and (5) annealing: transferring glass bottles into an annealing furnace with the temperature of 535-555 DEG C, keeping the temperature for 16-20 min, cooling down to 350-375 DEG C, keeping the temperature for130-150 min, and performing air cooling to the room temperature. The raw materials are reasonable in proportion, the fusion temperature is lower than 1,500 DEG C, and all technological steps work together to ensure that the produced glass bottles are high in transparency, almost free from internal stress, excellent in strength and resistant to shock chilling and shock heating.