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36 results about "Phagocytic index" patented technology

Phagocytic index any arbitrary measure of the ability of neutrophils to ingest native or opsonized particles determined by various assays; it reflects either the average number of particles ingested or the rate at which particles are cleared from the blood or culture medium.

Health food for improving immunity and preparation method thereof

ActiveCN102415568AEnhance immune functionEnhance humoral immune functionFood preparationBiotechnologyDisease
The invention discloses a health food for improving immunity and a preparation method thereof. The health food is prepared from the following raw materials in part by weight: 1 to 3 parts of dendrobium officinale, 2 to 6 parts of American ginseng and 6 to 18 parts of Chinese wolfberry. Pharmacological experiments prove that: the health food has an obvious effect of promoting an immune system, canobviously improve a phagocytic index of macrophage of immunosuppressed mice and increase coefficients of immune organs in nonspecifc immune experiments, can improve the conversion rate of lymphocytes, improve the level of immunoglobulin IgG, IgA and IgM in serum of the immunosuppressed mice and assist in conditioning immunodeficiency disease, and diseases such as weakened immune system, low resistance and the like.
Owner:常熟雷允上制药有限公司

Method for detecting activity of abdominal cavity phagocytic cells by flow cytometry

The invention discloses a method for detecting the activity of abdominal cavity phagocytic cells by a flow cytometry, which aims at providing a method for fast, accurately, simply and easily detecting the activity of the phagocytic cells through the quantitative analysis on the number of phagocytic yeasts of the phagocytic cells on the basis of eliminating the influence of unendocytosed fluorescence yeast cells on the analysis results. The method comprises the following steps: preparing beer yeast cell freeze-dried powder; using FITC to mark the beer yeast cells; carrying out incubation on the suspension liquid of the fluorescence marked beer yeast cells and the blood serum of the mice at the room temperature; adding the suspension liquid of the abdominal cavity phagocytic cells into a hole of a culture plate; adding the fluorescence marked beer yeast cells after the incubation with the blood serum of the mice and the identical suspension liquid of the abdominal cavity phagocytic cells into the rest holes in the cell culture plate; carrying out wall adherence incubation on the cell culture plate; and using the flow cytometry to obtain data and carrying out analysis on the data. The method of the invention accurately measures the phagocytic rate and the phagocytic index, and has good repetitiveness.
Owner:TIANJIN UNIV OF COMMERCE

Sealwort and ginseng formula for enhancing immunity and relieving fatigue and preparation method of formula

The invention discloses a traditional Chinese medicine formula and a preparation method of the traditional Chinese medicine. According to the formula, the traditional Chinese medicine is prepared from sealwort, ginseng (artificial planted) and poria cocos in a weight ratio of (50-100): (5-40): (10-50). The traditional Chinese medicine is prepared by the following steps of drying; crushing; extracting; drying and the like and has the functions of enhancing immunity and relieving fatigue (boosting qi and nourishing yin). The traditional Chinese medicine has the effects of raising the half value (HC50) of hemolysin of mice serum to different extents and increasing the phagocytic index (a) of mice, which means that the traditional Chinese medicine can be used for enhancing the humoral immune function and mononuclear-macrophage function and exerting a function of boosting immunity. The traditional Chinese medicine can be prepared into various dosages such as tabletted candies, tea bags, instant tea, troches, capsules, powder, pills, granules, oral liquids, injections and the like by using a modern preparation technology, and has good development and application prospects in preparation of drugs, health care foods or foods.
Owner:HANGZHOU JUQIAN BIOTECH

Lactobacillus rhamnosus and application thereof

The invention aims to provide lactobacillus rhamnosus having bacteriostatic and immunity enhancement function, with the preservation number: CCTCC NO: M 2013355. The lactobacillus rhamnosus provided by the invention can be applied in the biological products which are medicines, food or health products. The lactobacillus rhamnosus has very powerful bacteriostatic ability, can obviously improve the achroacyte conversion and HCso of a mouse, phagocytosis rate and index of macrophage and NK cell activity, can enhance normal mouse immunity, and therefore can be widely applied in the medicines, food or the health products.
Owner:QINGDAO VLAND BIOTECH GRP

Protein peptide powder for enhancing immunity and preparation method and application thereof

The invention relates to protein peptide powder for enhancing immunity and a preparation method and application thereof. The protein peptide powder is prepared from the following raw materials by weight: 30%-45% of marine fish skin collagen oligopeptide powder, 30%-50% of soybean oligopeptide powder, 10%-20% of Isomaltooligosaccharide, 8%-13% of polydextrose and 0%-0.5% of a sweetener. The protein peptide powder can increase macrophage phagocytic rate and phagocytic index and serum hemolysin content, enhances lymphocyte proliferation and NK cell activity, promotes antibody formation cell number increase, improves the body's immunity, and enhances body immunity.
Owner:GUANGZHOU BAIYUSN GUANGHUA PHARMA

Application of arctigenin in preparation of anti-infectious immunity drugs

The invention provides application of arctigenin in preparation of anti-infectious immunity drugs, which belongs to the field of medicine. Arctigenin is a natural monomer extracted from the traditional Chinese medicine burdock; it is discovered that arctigenin can substantially improve the clearance index and the phagocytic index of an immunocompromised patient and enhance non-specific immunity of the patient, exerts good treatment effects on infection caused by parasites, bacteria and viruses and especially has an excellent treatment effect on infectious diseases caused by Gram-positive bacteria. Arctigenin has the advantages of definite therapeutic effects, small toxic and side effects and wide medical application prospects when used for treatment of infectious diseases.
Owner:LUNAN PHARMA GROUP CORPORATION

Composite feed for improving immunity of herring and preparation method thereof

The invention discloses a composite feed for improving immunity of herring. The feed comprises the following components by weight portion: 3-6 parts of a fish meal, 15-25 parts of a soybean meal, 2-5 parts of a meat and bone meal, 4-6 parts of wheat bran, 4-8 parts of rice chaff and 5-10 parts of compound vitamin; and the feed also comprises 5-15 parts of Chitosan Oligosaccharide and 10-20 parts of konjac mannan oligosaccharide. The feed provided by the invention has effects of enhancing body function and immunity of herring, and the effects are reflected in the significantly increased immune indexes including superoxide dismutase, phagocytic percentage and phagocytic index of herring; and the feed provided by the invention has extensive component sources and low price, and is suitable for large-scale cultivation.
Owner:JURONG CITY GUOZHUANG TOWN NANHE FARM

Method for identifying function and capability of cells for phagocytizing exogenous foreign bodies

The invention discloses a method for identifying and researching the function and capability of cells for phagocytizing exogenous foreign bodies. The method comprises the following steps: preparing an infection source; performing mixed culture; directly observing the whole process that the researched cells phagocytize the infection source and cysts under a fluorescence microscope; and analyzing changes of phagocytic capability of the researched cells under different conditions so as to obtain phagocytic indexes. The method is characterized in that in the step of preparing the infection source, escherichia coli for expressing green fluorescent protein is taken as the infection source. In the method, the escherichia coli capable of expressing the green fluorescent protein is taken as the infection source so as to research the phagocytosis of various cells; and the method is intuitive, accurate, fast and convenient and can be also used for distinguishing the types of cells with a phagocytic function.
Owner:SHANGHAI OCEAN UNIV

Herba dendrobii composition with immunity improving function and preparation method of herba dendrobii composition

The present invention discloses a Dendrobium composition and preparation method with enhanced immune function.Dendrobium compositions are composed of Dendrobium, astragalus, jujube, wolfberry, longan meat, Poria, yellow essence, and hybrid maltose, which can exert the overall adjustment advantage of compound traditional Chinese medicine. It can regulate the body's immune function and small toxic side effects.Experiments have confirmed that it can promote the proliferation and transformation of mice lymphocytes and the devouring ability of macrophages, which can improve the activity of serum hemolytin levels, carbon outlines, and NK cells.In human health.
Owner:广东力之宝生物科技有限公司

Traditional Chinese medicine composition for improving organism immunity and preparation method thereof

The invention discloses a traditional Chinese medicine composition for improving the organism immunity and a preparation method thereof. The traditional Chinese medicine composition is prepared by using radix codonopsis, poria cocos, rhizoma acori graminei and polygala tenuifolia as raw materials. The invention also provides the preparation method of the traditional Chinese medicine composition for improving the organism immunity. Animal pharmacodynamic results show that after the traditional Chinese medicine composition provided by the invention is taken, the phagocytic index and the phagocytic rate of mouse peritoneal macrophages can be obviously improved; the result shows that the traditional Chinese medicine composition can enhance the non-specificity immunocompetence of the organism. In addition, the traditional Chinese medicine composition has the advantages that the content of the normal mouse serum hemolysincan can be obviously increased; the result shows that the effect of enhancing the mouse humoral immune function is achieved.
Owner:GUANGXI WUZHOU PHARMA GRP

Medicine composition for improving human body memory as well as preparation method and purpose thereof

The invention discloses a medicine composition for improving the human body memory and a preparation method thereof. The medicine composition is prepared from the following raw materials in parts by weight: 10 to 100 parts of radix ginseng, 10 to 100 parts of fructus alpiniae oxyphyllae, 5 to 80 parts of mulberries and 5 to 80 parts of rhizoma anemarrhenae. Through experiment verification, the medicine composition can reduce the expression of hippocampi CA1 region A beta protein; the study memory ability of dementia mice caused by scopolamine can be obviously improved; the study memory ability of IBO substrate nuclear microinjection dementia model rats is improved. Meanwhile, the medicine composition can increase the carbon clearance index, the phagocytic index, the thymus index and the spleen index, and has the effect of improving the immunologic function. The medicine is formed by combining natural medical raw materials or medical raw material extracts, and has the advantages that the curative effect is good; no toxic and side effects exist; the tolerance cannot be easily generated, and the like.
Owner:北京京师脑力科技有限公司

Application of lachnum water-soluble melanin SLIM404 in raising immunity

An application of lachnum water-soluble melanin SLIM404 in raising immunity. The invention belongs to the field of immunity in medicine and provides lachnum melanin SLIM404 and specifically relates to an application of the melanin in raising immunity and in preparing medicines for raising immunity. The melanin is intracellular melanin of lachnum YM404 and is a water-soluble lachnum melanin obtained after sulfur trioxide-pyridine modification. The melanin has an effect of raising immunologic function, and raises immunity by promoting thymus organ development, raising phagocytosis percentage and phagocytic index of macrophage, enhancing B cell-mediated humoral immunity, promoting a T cell-mediated immune response, increasing activity of an in-vivo antioxidant enzymatic system and removing excess free radicals and lipid peroxide in the immunocompromised body and the like. A medicine prepared from the melanin has various routes of administration, is safe and nontoxic, is easy to prepare and is suitable for large-scale popularization and application.
Owner:HEFEI UNIV OF TECH

Composition and preparation method thereof

The invention provides a composition. The composition is prepared from the following components in parts by weight of 1 to 8 parts of herba cistanche, 1 to 8 parts of radix astragali seu hedysari, 1 to 8 parts of fructus ligustri lucidi and 1 to 8 parts of fructus lycii. The medicinal materials of the composition supplement each other and can be taken as a health-care product for a long time. Pharmacodynamic experiments prove that the composition can significantly enhance the delayed allergic reaction and carbon clearance phagocytic index of mice and enhance the phagocytic function of peritoneal macrophages, and has the effect of significantly enhancing immunity.
Owner:JIANGSU KANION PHARMA CO LTD

Preparation method of functional yam-flavored wine

The invention discloses a preparation method of functional yam-flavored wine and belongs to the technical field of preparation of functional wine. The preparation method comprises steps as follows: preparation of a yam saccharification liquid, preparation of glutinous rice saccharification mash, dry yeast activation, mixed fermentation, clarification, ageing and sterilization. The yam-flavored healthcare wine has stable quality, mellow taste and good healthcare effects. Yam has the functions of reducing blood glucose, resisting oxidation, delaying senescence and resisting tumor and mutation and can improve the intestinal function. Yam polysaccharide can enhance the capability of lymphocyte proliferation, has a function of promoting antibody generation and can obviously increase the macrophage phagocytosis percentage and phagocytic index under the condition of low immune function caused by cyclophosphamide, promote formation of mature hemolysin and hemolysis plaque and conversion of lymphocyte and remarkably increase the peripheral T-lymphocyte ratio.
Owner:安徽孔氏奇医药科技有限公司

Probiotic composition suitable for intestines and stomach

The invention provides a probiotic composition suitable for intestines and stomach, and relates to the technical field of probiotic compositions. The probiotic composition suitable for intestines and stomach comprises a probiotic group, an unsaturated fatty acid group, a plant polysaccharide group, protease, lipase and a vitamin group. The unsaturated fatty acid group composed of linoleic acid, linolenic acid and arachidonic acid cooperates with the probiotic group to achieve the effects of promoting blood circulation and reducing the content of cholesterol in blood; the plant polysaccharide group composed of rhamnose, fucose, mannose and uronic acid cooperates with the probiotic group to improve the phagocytic index of macrophages of a body, and moreover, production of antibodies can be stimulated, so that the immune function of the human body can be enhanced; and the vitamin group consisting of a vitamin K1 and a vitamin U, and the protease and the lipase cooperate with the probiotic group, so that the composition can resist gastric ulcer, protect and repair gastric mucosa tissues, keep gastric cells active and vigorous, and reduce the probability of lesion.
Owner:河北源民生物科技有限公司

Double-effect dropping pills for enhancing immunity and memory of human body and preparation method thereof

The invention provides double-effect dropping pills for enhancing the immunity and memory of a human body and a preparation method thereof and belongs to the technical field of fine and deep processing of agricultural and sideline products and comprehensive utilization of by-products of the agricultural and sideline products. The pine seed source assisted double-effect dropping pills for enhancing the immunity and memory of the human body are obtained through matrix deployment, condensing agent deployment, peptide powder and matrix deployment, dropping pill preparation and processing, cooling, drying and other operations, wherein the molecular weight of the dropping pills is 3000-10000 Da, the carbon clearance phagocytic index of the dropping pills is 6.5%-8.5%, the fluorescent microsphere phagocytosis rate of peritoneal macrophages is 25%-35%, the incubation period of a channel water maze is short, error times are few, the appearance (high hardness, good rounding and trailing absence) of the dropping pills is high in quality, the dissolution time limit is less than 8 minutes, and the pill weight difference is below 0.2 g.
Owner:JILIN UNIV

Preparation method of hyriopsis cumingii polysaccharide

The invention relates to a method for preparing hyriopsis cumingii polysaccharide, which comprises following steps: crushing hyriopsis cumingii, extracting with hot water, filtering with 60-100 orders, condensing filter liquor, then, adding ethanol to deposit, re-dissolving deposition with hot water, adjusting the pH value to be 7-10, adding remixed proteinase 0.3%-0.6% according to a protein weight gage in re-dissolved materials, carrying out enzymatic hydrolysis for 4-8 hours under the temperature of 30-60DEG C, wherein components of the remixed remixed proteinase comprise: alkaline protease (Alcalase) and compound protease (Protamex) which are mixed equivalently, killing enzyme for the materials after the enzymatic hydrolysis under the temperature of 80-90DEG C, using the ethanol to deposit for the second time, drying the deposition in the vacuum, crushing over 60 orders, and obtaining products of the hyriopsis cumingii polysaccharide. Experiments show that the hyriopsis cumingii polysaccharide which is prepared by the method of the invention has the ability to induce the mouse spleen lymphocytes to proliferate, the hyriopsis cumingii polysaccharide can increase the volume value of mice serum hemolysin and can increase the phagocytic rate and the phagocytic index of chicken-red cells phagocytosis in mouse peritoneal, and the hyriopsis cumingii polysaccharide has a pluralityof biological activity and has the application prospect as medicinal resources and healthy food.
Owner:ZHEJIANG GONGSHANG UNIVERSITY

Medicine composition for improving immune function of human body as well as preparation method and application

The invention discloses medicine composition for improving the immune function of a human body and a preparation method of the medicine composition. The medicine composition is prepared from components of raw materials in parts by weight as follows: 8-80 parts of ficus hirta, 5-60 parts of radix angelicae sinensis and 1-30 parts of ganoderma lucidum. Experiments indicate that the medicine composition has the function of improving the immune function of the human body, the influence of the medicine composition on carbon particle clearance indexes, phagocytic indexes, thymus indexes, spleen indexes and other indexes of immunosuppressed mice is higher than that in two-two compatibility group, and results indicate that the components have a synergistic function. Besides, the medicine composition can remarkably reduce the TC and TG level in serum of the mice and has a blood fat reduction function.
Owner:北京京师脑力科技有限公司

Application of traditional Chinese medicine composition in preparation of drug for improving immunity

The invention belongs to the field of traditional Chinese medicine preparations, and particularly relates to an application of a traditional Chinese medicine composition in preparation of a drug for improving immunity. The traditional Chinese medicine composition is mainly prepared from cibot rhizomes, cherokee rose fruits, suberect spatholobus stems, philippine flemingia roots, scarlet kadsura stems, beautiful millettia roots, glossy privet fruits, Chinese taxillus herb, dodder seeds, rhizoma corydalis, shinyleaf pricklyash roots, frankincense and myrrh. Experiments prove that the traditionalChinese medicine composition prepared by the invention can obviously increase the body weight of mice with reduced immune function, obviously (P<0.01) improves the clearance of charcoal particles, has the tendency of increasing the phagocytic index, and has the effect of obviously improving the immunity.
Owner:GUANGZHOU CHEN LI JI PHARMA FACTORY

Composition with immunity enhancement effect and application of composition in preparation of immunoenhancement drugs and health food

The invention provides a composition with an immunity enhancement effect and belongs to the technical field of immunoregulation drugs. The composition comprises garlic lectin, alliin and garlic polysaccharide in a mass ratio being (0.4-0.6):(0.8-1.2):(17-25). The composition can increase a spleen index and a thymus index of immunosuppression mice, increase total white blood cells, a clearance index K and a phagocytic index alpha and ensure content levels of IL-2, TNF-alpha and IFN-gamma in serum to approach to normal levels and has the significant immunity enhancement effect.
Owner:XINJIANG AILEXIN PHARMA

Preparation method and application of liver cancer immunogen Z1

The invention discloses a preparation method and application of liver cancer immunogen Z1, belonging to the technical field of biological engineering. The preparation method provided by the invention comprises the following steps of: inoculating H22 liver cancer cells in a culture medium, simultaneously adding lentinan to co-culture, taking out after culturing, repetitively freezing, thawing and crushing the cells, centrifugally separating to obtain supernate, adding ammonium sulphate into the supernate to salt out, and separating and collecting precipitate after salting out so as to finally obtain the liver cancer immunogen Z1. If a mouse is inoculated with the immunogen prepared by the preparation method provided by the invention, the survival rate of the mouse can be effectively prolonged; compared with a control group, the survival rate of the mouse inoculated with the immunogen prepared by the invention can be increased by 100%; the thymus index and the spleen index are up to 2.68 and 4.56 respectively; the phagocytic rate and the phagocytic index of macrophage are up to 52% and 3 respectively; and the serum antibody titer of the mouse is up to 25600x.
Owner:潍坊峡山维泰生物科技有限公司

Health-care composition and capsule for improving immunity function and preparation method of health-care composition and capsule

The invention relates to a health-care composition and capsule for improving an immunity function and a preparation method. The content of the compound health-care capsule is prepared from the following raw materials in percentage by weight: 25-35% of NMN, 10-15% of ganoderma lucidum spore powder, 10-15% of dendrobium officinale powder, 8-12% of a moisture-proof agent and a flow aid, 30-40% of an adhesive and a diluent and 2-3% of a lubricant. Compared with the prior art, the capsule shell can cover the unpleasant odor of the NNM raw material medicine, contact of light, air and moisture is avoided, and the stability and bioavailability of the medicine are improved; the compound health-care composition can improve the thymus index of a mouse, reduce the ear swelling degree of the mouse, promote lymphocyte proliferation and increase the phagocytic index and NK cell activity of the mouse. The NMN compound health-care capsule prepared by the invention is uniform in content, good in in-vitro dissolution behavior, simple in production process, better in stability and easy for large-scale production.
Owner:SHANGHAI INST OF TECH

A kind of feed additive and its preparation method and application in aquatic animal feed

The invention relates to a feed additive. The feed additive is prepared from a volatile oil mixture and a carrier, wherein the mass ratio of the volatile oil mixture to the carrier is 1 to (4-8), the volatile oil mixture is prepared by mixing turmeric volatile oil, fiveleaf gynostemma herb volatile oil and atractylodes rhizome volatile oil, and the carrier is beta-cyclodextrin. The invention further relates to a preparation method and application of the feed additive in a feed for aquatic animals. Compared with the prior art, if the feed additive disclosed by the invention is applied to the feed for the aquatic animals, the antioxidant ability of the aquatic animals can be notably improved, the total antioxidant ability of serum and the activity of superoxide dismutase can be improved, the antioxidant ability of organisms can be improved, the oxidative damage of the organisms can be avoided, the immunity of the aquatic animals can be improved, the lysozyme vitality and complement vitality in the serum of the aquatic animals can be improved, the leucocyte phagocytic index in the serum can be increased, the health of the organisms can be improved, the growth rate and the survival rate of the aquatic animals can be increased, the growth is promoted, and a theoretical basis is laid for the development of the green raising of the aquatic animals.
Owner:NINGBO INST OF TECH ZHEJIANG UNIV ZHEJIANG

Light source module capable of improving human immunity and lighting device

The invention relates to the technical field of lighting equipment, and particularly relates to a light source module capable of improving human immunity and a lighting device.The light source module comprises a substrate and light sources arranged on a clamping plate, and the light sources comprise a lemon light source, a red light source and an infrared light source; the wavelength of light emitted by the lemon light source is 567-587 nm, and the spectral power of the lemon light source accounts for 30-35% of the total power of the light source; the wavelength of light emitted by the red light source is 620-700 nm, and the spectral power of the red light source accounts for 30-35% of the total power of the light source; and the wavelength of light emitted by the infrared light source is 760nm-1mm, and the spectral power of the infrared light source accounts for 30-35% of the total power of the light source. The light source module is provided with the lemon light source, the red light source and the infrared light source so that the phagocytic rate and the phagocytic index of macrophages can be enhanced, and the immunity of organisms (including human bodies) can be improved.
Owner:GUANGDONG COSIO LIGHTING

Composition for improving immunity and preparation method thereof

The invention relates to the technical field of health products, in particular to a compound for improving immunity and a preparation method thereof. The compound is prepared by combining apple stem cell freeze-dried powder with paecilomyces hepiali fungus powder, and can be used for remarkably improving immunity of a human body. Tests show that after gavage in a mouse with the compound, the monocyte-macrophage phagocytic index of the mouse can be increased from 1.19 plus or minus 0.17 to 1.43 plus or minus 0.23, a significant difference is realized, and the NK cell activity of the mouse is improved from 26.84% plus or minus 13.52% to 28.96% plus or minus 13.65%. After the compound is taken by 300 low-immunity people, survey results show that 99% of the people consider the compound to be an efficacious medicine, and the percentage is remarkably higher than that obtained from a control group.
Owner:GUANGZHOU KOHEALA BIOTECHNOLOGY CO LTD

Method for detecting activity of abdominal cavity phagocytic cells by flow cytometry

The invention discloses a method for detecting the activity of abdominal cavity phagocytic cells by a flow cytometry, which aims at providing a method for fast, accurately, simply and easily detecting the activity of the phagocytic cells through the quantitative analysis on the number of phagocytic yeasts of the phagocytic cells on the basis of eliminating the influence of unendocytosed fluorescence yeast cells on the analysis results. The method comprises the following steps: preparing beer yeast cell freeze-dried powder; using FITC to mark the beer yeast cells; carrying out incubation on the suspension liquid of the fluorescence marked beer yeast cells and the blood serum of the mice at the room temperature; adding the suspension liquid of the abdominal cavity phagocytic cells into a hole of a culture plate; adding the fluorescence marked beer yeast cells after the incubation with the blood serum of the mice and the identical suspension liquid of the abdominal cavity phagocytic cells into the rest holes in the cell culture plate; carrying out wall adherence incubation on the cell culture plate; and using the flow cytometry to obtain data and carrying out analysis on the data. The method of the invention accurately measures the phagocytic rate and the phagocytic index, and has good repetitiveness.
Owner:TIANJIN UNIV OF COMMERCE

An alkaline plant salt boosting immunity and a preparing method thereof

An alkaline plant salt boosting immunity is provided. The alkaline plant salt comprises a suaeda salsa plant salt, a undaria pinnatifida extract product, dry banana powder, a cordyceps militaris sporocarp extract product, a common yam rhizome extract product, a cassia seed extract product, amorphophallus konjak powder, tea polyphenols and fucoidin. A preparing method of the alkaline plant salt is also provided. The alkaline plant salt is capable of increasing weights of immune organs, boosting body fluid immunity, increasing the hemolysin content, boosting nonspecific immunity of mice, significantly increasing the phagocytic index and phagocytic activity of phagocytes of mice, improving delayed hypersensitivity of mice and increasing the quantity of antibody producing cells.
Owner:王胜

A preparation method and application of liver cancer immunogen z1

The invention discloses a preparation method and application of liver cancer immunogen Z1, belonging to the technical field of bioengineering. The method provided by the present invention is to inoculate H22 liver cancer cells in the culture medium and add lentinan for co-cultivation, take out after the culture, repeatedly freeze-thaw and break the cells, centrifuge to obtain the supernatant, add ammonium sulfate to the supernatant for salting After the salting out, the precipitate was separated and collected, and finally the liver cancer immunogen Z1 was obtained. Utilizing the immunogen prepared by the preparation method provided by the present invention to inoculate mice can effectively prolong the survival rate of mice. Compared with the control group, the survival rate of mice inoculated with the immunogen prepared by the present invention can be increased by 100%. The index and spleen index reached 2.68 and 4.56 respectively, the phagocytosis rate and phagocytosis index of macrophages reached 52% and 3 respectively, and the mouse serum antibody titer reached 25600×.
Owner:潍坊峡山维泰生物科技有限公司
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