1223 results about "Gamma-Aminobutyric acid" patented technology

A method for preparing a highly purified N-long chain acyl neutral amino acid for use of a detergent and the like in a simple and convenient manner and in a high yield by reacting a neutral amino acid such as glycine, gamma-aminobutyric acid, and alanine, with a saturated or unsaturated fatty acid halide having 8 to 22 carbon atoms, wherein the reaction is performed in a mixture of water and one or more kinds of hydrophilic organic solvents selected from the group consisting of acetone, acetonitrile, a secondary alcohol having 3 or 4 carbon atoms, and a tertiary alcohol having 4 carbon atoms such as isopropanol, sec-butanol, and tert-butanol in the presence of a base.

The invention relates to a method for preparing health-benefiting fermented soybean meal enriched in small peptides, gamma-aminobutyric acid (GABA), reducing sugar, lactobacillus plantarum and antimicrobial peptide. By utilizing strains of aspergillus oryzae, saccharomyces cerevisiae, bacillus subtilis and lactobacillus plantarum, the small peptides, free amino acids, reducing sugar, GABA and high viable count content in the lactobacillus plantarum in the health-benefiting fermented soybean meal are obtained through the two-stage solid state fermentation method, the small peptides account for 8.01-18 percent, the free amino acids has the content of 80-300mg / g, the reducing sugar reaches 20-80mg / g, the GABA reaches 0.317-0.5mg / g, the viable count content in the lactobacillus plantarum is 2-6.5*1010cfu / g, the antibacterial titer of antimicrobial peptides is 2.0*103-7.0*104 IU / g, and the yield of the health-benefiting fermented soybean meal is 82.03-90 percent. According to the process, the nutrient effect of the soybean meal can be improved, the prepared fermented soybean meal has the antibacterial effect, partial antibiotics can be replaced, the fermented soybean meal is conveniently preserved and saved, the process is simple and feasible, and the fermented soybean meal is green and environment-friendly and has application significance and wide prospect in the feed industry and breeding industry.

The present invention provides a method of treating pain and pain related conditions by administering to a patient in need thereof, a therapeutically effective amount of a slow release Tapentadol Hydrochloride and therapeutically effective amount of a second analgesic, wherein the second analgesic is tramadol, gamma-aminobutyric acid (GABA) analogue or an NSAID. The present invention further provides a pharmaceutical composition comprising a therapeutically effective amount of a slow release Tapentadol Hydrochloride and a therapeutically effective amount of a second analgesic, wherein the second analgesic is tramadol, gamma-aminobutyric acid (GABA) analogue or an NSAID.

A protocol or procedure is provided for lowering sympathetic nervous system arousal in a person in order to prepare that person for a medical or dental procedure. First, a therapeutic dosage of one or more neurotransmitter supplements, such as a gamma aminobutyric acid formulation, a tryptophan-derived neurotransmitter precursor, and dehydroepiandrosterone are administered to the patient. Concomitantly, gelled electrodes are placed adjacent or below the mastoid. The gelled electrodes are connected to a cranial electrotherapy stimulation device that administers a sub-sensation level current to the patient. Also, a noise dampening headset is placed on the patient and a neuroacoustic entrainment recording or program is played. Next, light is blocked with black out glasses. Then, the medical or dental procedure is performed.

The invention provides a novel high gamma-aminobutyric acid, high flavone fragrant black glutinous germinating brown rice and preparation thereof. The germinating brown rice is produced from material of long-shaped fragrant glutinous black rice, which has gamma-aminobutyric content 89mg / 100g, flavone content 8603mg / kg, and protein content 12.4%, wherein the content of amino acid and mineral substances is 3-5 times higher then the ordinary rice. The preparation includes material selecting, husk sieving, sterilizing, cleaning, immersing, sprouting, cleaning, terminating activity of enzyme, microwave drying, checking. The germinating brown rice has thick fragrance of popcorn, great mouth feeling, high content of gamma-aminobutyric acid, flavone and protein, high content of amino acid and mineral, high nutrition value. The germinating brown rice has reasonable materials, easy processing, enhances quality of germinating brown rice, prolongs storage period of the product, has obvious economic value, and provides technological guarantee to popularization of the germinating brown rice as a functional food.

The present invention relates generally to pharmaceutical dosage forms having immediate release and controlled release properties that contain a γ-aminobutyric acid (GABAB) receptor agonist, e.g., baclofen, for the treatment of medical conditions, which includes spasms, cramping, and tightness of muscles, associated with ailments such as multiple sclerosis or certain spinal injuries.

The invention discloses a preparation method and product of germinated wheat rich in gamma-aminobutyric acid, and the method is used for solving the problems of bad existing effect and unstable yield since GABA is enriched by utilizing tea and rice products according to an existing method for preparing gamma-aminobutyric acid based on a biological concentration method. The method comprises the following steps of: raw material selection, pretreatment, imbibition, temperature control training and germination termination. Wheat seeds are dramatically taken as raw materials, the improvement of GAD enzyme activity in wheat seeds is effectively promoted by controlling germination conditions, a cultivated substrate and the pH value, and meanwhile the GAD activity is ensured by controlling the pH value, the activity of GABA aminopherase is inhibited, and the content of gamma-aminobutyric acid in germinated wheat is greatly improved, so that the nutritive value of wheat is greatly improved. Experimental results show that the content of GABA in the prepared germinated wheat is 31.08 mg per 100 g at most, and achieves domestic and international leading level of similar methods.

The invention relates to a production process of germ and corn composite nutritional powder and the product of the production process, and belongs to the technical field of food processing. The production process is characterized in that mixing corn which sprouts in stress with wheat germ which is subjected to microwave enzyme inactivation; performing extrusion and superfine grinding to prepare germ and corn meal; adding carrot meal, spirulina meal, white granulated sugar, maltodextrin and vegetable fat powder into the germ and corn meal; and sterilizing and packaging to prepare the germ and corn composite nutritional powder. The production process is simple and high in industrial degree, so that the germ resource can be further utilized, corn can be completely utilized, and the additional value of agricultural products can be increased. The germ and corn composite nutritional powder produced by the production process is good in dissolubility, fine in taste and high in nutritional value, is rich in gamma-aminobutyric acid, glutathione, octacosanol, dietary fiber and other components, has the functions of improving brain functions, calming nerves, improving sleeping, resisting oxidation, delaying senescence, improving body immunity and the like, and is an ideal health-care nutritional food, wherein the content of gamma-aminobutyric acid in the product is between 20 and 60mg / 100g.

The invention discloses a sleeping-aid beverage. A sleeping-aid composition is composed of, by mass, at least one of 0.001-0.4 part of gamma-aminobutyric acid, 0.001-0.4 part of theanine, 0.001-0.4 part of spine date seed extract, 0.001-0.4 part of valerian root extract and 0.001-0.4 part of chamomile extract. The sleeping-aid composition is used for preparing a sleeping-aid product. The sleeping-aid beverage comprises the sleeping-aid composition and water. Gamma-aminobutyric acid, theanine, spine date seed extract, valerian root extract and chamomile extract in the beverage can play a role in keeping people calm, soothing nerves and improving sleeping quality, and can also have a certain effect on relieving pressure and promoting sleeping when independently used; due to the addition of minerals, vitamin C and B-vitamins, the nutritional value of the beverage can be increased, and the sleeping promoting effect can be improved.

The invention provides a sleep improvement composition. The sleep improvement composition is composed of gamma-aminobutyric acid, a spine date seed extract, magnesium and vitamin B6. The invention also provides a preparation of the sleep improvement composition and a preparation method of the sleep improvement composition. The sleep improvement composition contains no hypnotic components, and can effectively calm motion and improve the sleep for high-pressure populations and poor sleepers.

A peptide of the formula Iwherein X is hydrogen, glycine, alanine, leucine, isoleucine, valine, N-valine, proline, tyrosine, phenylalanine, tryptophan, D-alanine, D-leucine, D-isoleucine, D-valine, D-N-valine, D-proline, D-tyrosine, D-phenylalanine, D-tryptophan, gamma-aminobutyric acid or ζ-aminocaproic acid; A is D-gluptamic acid or D-y-glutamic acid; and Y is glycine, alanine, leucine, isoleucine, valine, N-valine, proline, tyrosine, phenylalanine, tryptophan, D-alanine, D-leucine, D-isoleucine, D-valine, D-N-valine, D-proline, D-tyrosine, D-phenylalanine, D-tryptophn, gamma-aminobutyric acid, ζ-aminocaproic acid, hydroxyl, or an amide group.

Methods for treating a central nervous system (CNS) injury in a subject are provided. Aspects of the methods include administering to the subject an effective amount of gamma aminobutyric acid (GABA) receptor signaling inhibitor to treat the subject for the CNS injury. Also provided are compositions finding use in embodiments of the methods. Methods and compositions of the invention find use in the treatment of a variety of different CNS injuries, including but not limited to, treating a subject for CNS injury associated with the occurrence of stroke.

The invention discloses a beverage capable of maintaining beauty and nourishing the skin and a preparing method of the beverage. The beverage capable of maintaining beauty and nourishing the skin is prepared from collagen tripeptide, chitosan oligosaccharide, gamma-aminobutyric acid, fish collagen peptide and skipjack elastin peptide. The beverage achieves great effects of adjusting and repairingthe skin of the human body in combination with multiple collagen nutrients, vitamin C and nutrient substances resistant to sugar and oxidation required for the human body.

The invention provides a tablet candy and a producing method thereof. The tablet candy is made of the following raw materials according to weight percent: 73.9-85% of sorbitol, 2-5% of flaxseed powder, 0.1-0.3% of L-theanine, 0.1-0.5% of gamma-aminobutyric acid, 0.5-2% of phosphatidylserine, 5-10% of xylitol, 0.1-0.3% of sucralose, 0-5% of flavoring essence, 0-0.1% of colorant, and 1-3% of magnesium stearate. In the tablet candy of the invention, flaxseed powder, L-theanine, gamma-aminobutyric acid and phosphatidylserine interwork according to certain proportion and in synergy, promote mutually, can effectively relieve pressure, tranquillize mood, calm sentiments, and improve memory and thinking capability, so that the tablet candy has health care functions of relieving pressure, relaxingmood, enhancing memory and the like, and is suitable to be eaten by common people as well as diabetics, obese people or people hoping to reduce weight.

The invention relates to a relaxing beverage for relaxing metal pressure and improving sleeping, belonging to the field of functional food. The beverage is prepared from soothing factors (such as tea extract, spine date seed extract and gamma-aminobutyric acid) and nutrient substances (such as vitamins and mineral substances) which are matched in a liquid base stock; and a series of relaxing beverages are prepared respectively according to the product design requirements and the different taste requirements of consumers. The product not only has the advantages of replenishing water and nutrient substances, but also has the efficacies of resisting the fatigue and relaxing the metal pressure.

The invention relates to highland barley with rich gamma-aminobutyric acid and a preparation method thereof, belonging to the technical field of fine and further processing of the highland barley. The preparation method comprises the steps of: sterilizing the highland barley, adding a calcium chloride solution for soaking, adjusting pH value, spraying a vitamin B6 solution, drying and obtaining a finished product. The highland barley has the beneficial effects that the highland barley germ takes the highland barley as a raw material to prepare germinated highland barley germ, and compared with the directly-extracted germ of the seed, the yield of the germ is improved by 200-300%; in the process of preparation, due to addition of the calcium chloride solution and vitamin B6 solution, the enrichment amount of GABA can be increased; the highland barley germ prepared by taking the highland barley as the raw material has rich nutritional value, also has prominent medical and health-care actions and lays a solid foundation for utilizing the highland barley germ; and the product can be used for health-care foods, functional beverages and the like with the functions of resisting fatigue and reducing blood pressure, so that the additional value of the highland barley is greatly improved.

The invention relates to a substance for curing or relieving pain, and provides application of a gamma-aminobutyric acid A receptor inverse agonist containing alpha 5 subunits in preparing a drug for preventing and improving or curing the pain and also provides a drug composition containing the substance for curing or relieving the pain.

The invention relates to nutrient powder of germinated brown rice and a production process thereof and belongs to the food processing technology field. The invention is characterized in that the germinated brow rice is used as the main material is expanded, crushed, screened, mixed with oatmeal, soybean powder and white granulated sugar, sterilized and packaged, finally the nutrient powder of the germinated brown rice containing health ingredients of gamma-aminobutyric acid (GABA) is made. The germinated brown rice is produced by extrusion and expansion, so the invention has the advantages of no agglomeration and no precipitation during pouring the water into the nutrient powder, convenient use, being easily to be digested and absorbed by human body, and 15 to 20 mg per 100g GABA in the product.

Subjects having at least one condition selected from the group consisting of mental retardation, Down's syndrome, fragile X syndrome and autism are treated with a composition that includes gamma-aminobutyric acid agonists and / or M1 muscarinic receptor antagonists. The gamma-aminobutyric acid agonist (GABA) can be a GABA(B) agonist, such as baclofen. GABA(B) agonists can be used in combination with Group I mGluR antagonists and M1 muscarinic receptor antagonists in methods of treating humans.

The invention discloses a method for preparing a brown rice enzyme yogurt. The preparation method mainly comprises the steps of pretreatment of raw materials, homogenization, sterilization, cooling, addition of brown rice enzyme and a ferment, fermentation, cooling, filling and refrigeration. The addition of the brown rice enzyme and the ferment is as follows: 3-7 parts by weight of the brown rice enzyme and 4-6 parts by weight of the ferment are added in 100 parts by weight of mixed solution after the treatment for carrying out inoculation; and the ferment is mixed culture solution of streptococcus thermophilus and lactobacillus bulgaricus. The brown rice enzyme is formed by fermenting brown rice, dozens of types of new enzyme can be derived when having the nutrition of the brown rice, and the brown rice enzyme yogurt is further rich in gamma-aminobutyric acid, glutathione, gamma-oryzanol, ceramide, lipopolysaccharides from rice bran, minerals and other nutritional components. The brown rice enzyme yogurt mixes the dual functions of the brown rice enzyme and the yogurt, is easy to be absorbed by human body and can improve the immunity of the human body and activate cells, thereby being the beneficial complement to modern dietary nutrition.

Fermented soybean foods rich in gamma-aminobutyric acid are produced by fermentation of soybean using Tempe molds. Fermented soybean foods rich in gamma-aminobutyric acid and free amino acids are produced by fermentation of soybean using Tempe molds with anaerobic treatment. Fermented cereal foods rich in gamma-aminobutyric acid and free amino acids are also produced by fermentation of cereals with anaerobic treatment. Rhizopus oligosporus and Rhizopus oryzae are favorably used as the Tempe mold and Koji molds.

The invention belongs to the research field of rice seed initiation technologies, and discloses a composite natural plant extract rice seed initiator as well as a preparation method and an application thereof. The composite natural plant extract rice seed initiator is prepared from the following raw materials by weight percent: 47.50-48.50% of a cany tea extract, 33.10-34.50% of a tea extract, 14.50-15.00% of a rosemary extract, 0.15-0.20% of vitamin B2, 0.15-0.20% of pantothenic acid, 0.15-0.20% of vitamin C, 0.15-0.20% of folic acid, 0.15-0.20% of gamma-aminobutyric acid and 2.00-3.00% of aloe vera gel freeze-dried powder. The composite natural plant extract rice seed initiator is reasonable in formula composition, fully utilizes the characteristics and the functions of all the raw materials, and the raw materials can be reasonably combined and matched, so that the best initiation effect can be obtained by the cooperation of the raw materials.

The invention discloses heat-stress-resistant fermented feed for a laying hen. The heat-stress-resistant fermented feed is prepared from the following raw materials: corn, soybean meal, cottonseed meal, apple pomace, chili meal, corn steep liquor sprayed corn husk, wheat bran, bacteria liquid, compound premixed feed and water, wherein the bacteria liquid is prepared from enterococcus aureus, bacillus subtilis, saccharomyces cerevisiae, brown sugar and water. The preparation method of the heat-stress-resistant fermented feed comprises the following steps: crushing the raw material, mixing the dried material, preparing the bacteria liquid, secondarily mixing the wet feed, and conducting anaerobic fermentation. The heat-stress-resistant fermented feed disclosed by the invention has the following benefits: the main essential nutrients in the fermented feed are approximate to that of complete feed for the laying hen and comprise active beneficial bacteria, gamma-aminobutyric acid, organic acid and other active factors; the feed can be added to the daily ration of the laying hen based on the rate of 5-15% to obviously improve the laying rate of the laying hen, the feed-gain ratio, the broken egg rate and the oxidation resistance, synergistically give play to multiple action of the beneficial bacteria on microecologic control to bacterial flora in the gastrointestinal tract, nerve regulation to the central nervous system by the neurotransmitter, and buffering of the organic acid to respiratory alkalosis due to high temperature, and obviously resist against the heat stress due to high temperature in summer for the laying hen.

The invention discloses blood pressure reducing and sleeping promoting health-care food. The health-care food comprises oligosaccharide, gamma-aminobutyric acid, theanine, taurine, 5-hydroxytryptophan, minerals and vitamins. The health-care food is reasonable in prescription and rich in nutrients, and can be used for effectively relieving physical and psychological stress, relaxing mind, promoting sleeping and reducing blood pressure.

The invention provides a germinated brown rice nutrition tablet and a preparation method thereof, and belongs to the technical field of fine and deep processing of agricultural and sideline products. The germinated brown rice nutrition tablet is prepared from germinated brown rice serving as a main raw material by germinating the brown rice, drying, cooling, tabletting, re-drying, cooling and sterilizing. The nutrition tablet is rich in gamma-aminobutyric acid, phytic acid, dietary fiber and nutritive elements such as vitamins B1, B2, B6 and E, is purely vegetarian and can be eaten. The germinated brown rice nutrition tablet is suitable for being eaten by normal crowds such as children, students, office workers, patients and the middle-aged and aged people, and is particularly suitable for people with overstrained nerves, people with gastrointestinal disorders and obese people, can be added into porridge, can also be put into rice to cook steamed rice, and can be added into tea cakes, cakes, biscuits, baby foods and the like as a raw material.

The invention belongs to the technical field of rice deep processing, in particular to a production method of a functional rice product which has a special sweet flavor and is rich in Gamma-aminobutyric acid and a product thereof, the rice product is produced by virtue of the activities of high glutamate decarboxylase, amylase and protease in germinated brown rice of an indica type rice or a non glutinous rice. The invention takes the indica type rice or the non glutinous brown rice as a raw material which carries out the steps of cleaning, disinfection, soaking, germination, cleaning, beating into rice milk, heat insulation, transformation, drum drying or spray drying, and the like, to be produced into functional nutrition rice flake or rice powder which is rich in Gamma-aminobutyric acid. Compared with the prior art, the rice product makes full use of the activities of the glutamate decarboxylase, the amylase and the protease in the germinated brown rice; the produced rice product has the special sweet flavor; by calculating based on dry basis, the content of Gamma-aminobutyric acid is high (1,000-1,400mg / 100g), and the nutritional value and the digestibility are high. The rice product of the invention can be taken as the functional food for resisting fatigue and reducing blood lipid.

The invention relates to a method for preparing a germinated brown rice ferment drink. Germinated brown rice is processed in an Aspergillus oryzae and Rhizopus oryzae mixed culture manner, is decomposed by using the enzyme system complementarity, and is inoculated with lactic acid bacteria to carry out fermentation. The prepared germinated brown rice ferment drink is rich in organic acids, variousfree amino acids, soluble dietary fibers, and active components which are gamma-aminobutyric acid and SOD, and has the advantages of sour-sweet mouthfeel, convenience in drinking, no additives, excellent nutrition and healthcare effects, great improvement of the raw material utilization rate in a two-stage fermentation process, and great solving of resource wastes of existing brown rice having bad mouthfeel.

Embodiments herein provide the formulation and use of gamma-aminobutyric acid (“GABA”) in combination with one or more of a herbicide and an insecticide. In one embodiment, the herbicide is glyphosate; in another, the insecticide is imidacloprid. Methods and formulations described and claimed herein may be useful for encouraging growth of desired plants while discouraging the growth of undesirable plants and / or pests. Method and formulations described and claimed herein may be useful for alleviating stress conditions for desirable plants, and for decreasing yield losses resulting from application of herbicides and / or insecticides.

The invention discloses a germinated whole grain and a preparation method thereof, and belongs to the technical field of deep processing of grains. The whole grain is subjected to ultrasonic washing, high-voltage pulsed electric field treatment, biological enzymolysis or combined high-voltage pulsed electric field and biological enzymolysis treatment in a soaking process, and a segmented soaking and germination manner for germination is adopted, so that the sensory quality, germination yield and quality of a germinated whole grain product are improved, and germination loss is reduced. The preparation method is simple, low in soaking and germination temperature, short in cycle, energy-saving and environment-friendly. The content of functional, nutritional and bioactive substances in the germinated whole grain product is remarkably increased, and food safety is remarkably improved. For example, for brown rice, germinated brown rice prepared by the preparation method has gamma-aminobutyric acid content of 303.8 to 312.6 mg / 100 g, glutathione content of 16.8 to 18.3 mg / 100 g, IP6 content of 460.8 to 484.4 mg / 100 g and dietary fiber content of 3.5 to 3.6 mg / 100 g.