7 results about "Tertiary alcohols" patented technology

N-Biarylmethylene substituted pyrrolopyridinone, pyrrolopyrazinone, pyrrolopyrimidinone, and isoindolin-1-one compounds having a tertiary alcohol-containing group substituted on the biarylmethylene are positive allosteric modulators of the muscarinic acetylcholine receptor M1 (mAChRM1). The compounds and pharmaceutical compositions may be used in treating neurological disorders, psychiatric disorders, or a combination thereof.

The present application provides a demercaptan agent consisting of: (1) at least one aminocarboxylate salt containing a primary amine group, a secondary amine group or a tertiary amine group, (2) at least one alcohol amine being a primary alcohol amine, a secondary alcohol amine or a tertiary alcohol amine, and (3) water. The present application also provides a preparation method and use of the demercaptan agent and a method for removing mercaptans from liquefied petroleum gas using the demercaptan agent. The demercaptan agent of the present application removes mercaptans by extraction without using inorganic bases such as sodium hydroxide, and the regenerated demercaptan agent can be regenerated by steam stripping, recycled and used, and no alkali residue is discharged. The demercaptan agent of the present application can be used for removing mercaptans from liquefied petroleum gas, and the total sulfur content of refined liquefied petroleum gas can be reduced to 5 μg·g ‑1 The following.

This invention belongs to the field of organic synthesis technology and relates to a method for preparing high-purity tertiary alcohols, comprising: (1) reacting the crude product of the compound shown in Formula I with p-nitrobenzoyl chloride; (2) recrystallizing the obtained product to obtain the compound shown in Formula II; and (3) hydrolyzing and distilling the compound shown in Formula II to obtain the pure product of the compound shown in Formula I, as shown below. The high-purity tertiary alcohol prepared by this method has a single impurity content of less than 0.1% and has been successfully applied to E-nerolidol, with a purity sufficient to meet the requirements for use as a pharmaceutical raw material. This method has high yield, low cost, and is suitable for industrial production.

Disclosed herein are methods for preparing tertiary alcohols from optionally substituted phenyl ketones or optionally substituted pyridyl ketones, the methods comprising the use of chiral ligands and boron trifluoride etherate. The tertiary alcohols can be used to prepare synthetic forms of natural products and / or drugs.

The invention provides a novel method for realizing conversion from tertiary alcohol to ester in one step through carbon-carbon bond oxidative cleavage. According to the method, the ester compound is prepared from the tertiary alcohol compound by reacting for 12-48 hours at 110-180 DEG C in the presence of a nitrate catalyst in an oxygen atmosphere, and the method has the following advantages: 1) the application range of a substrate is wide, and the yield of medium or above can be obtained; and 2) the method does not need additional addition of an initiator, an oxidant and the like, and has the advantages of simplicity in operation, high stability, capability of realizing gram-level scale amplification and the like. And 3) the method can realize functional group conversion of complex bioactive molecules.

The present invention discloses a polymerizable compound, a liquid crystal composition comprising the polymerizable compound, and a liquid crystal display device. The polymerizable compound is a compound represented by the following formula I, wherein Sp represents a single bond or a C1-C5 linear, branched or cyclic alkyl group, and the Sp groups are not both single bonds, wherein any one or more non-adjacent —CH2— can be replaced by —O—, —S—, —CO—, —CH2O—, —OCH2—, —COO—, —OOC—, or an acrylate group in such a manner that O- or S-atoms are not directly connected with each other, one or more H atoms can be independently replaced by F, C1, or G3, and at least one H atom is replaced by G3; G3 represents a C1-C7 tertiary alcohol structure; and X represents —CH2—, —O—, or —S—. In particular, the polymerizable compound has the advantages of good diffusivity, high stability of the formed polymer, and low residue after a UV process. It can be ensured that a display exhibits excellent IS performance under extreme conditions.

The present invention aims to provide a means for imparting adhesiveness to nails even without polishing. The present invention is a nail primer resin composition containing (A) and (B) components and not containing a photoradical initiator, the (A) component: at least one selected from the group consisting of a secondary alcohol having a (meth)acryl group and a molecular weight of 145 or more, and a tertiary alcohol having a (meth)acryl group and a molecular weight of 145 or more (wherein the (B) component is excluded); and the (B) component: a phosphate ester compound having a (meth)acryl group.