15 results about "Tertiary alcohols" patented technology

The disclosed and claimed subject matter relates to formulations comprising a combination of (i) one or more alkynes and (ii) one or more tertiary alcohols and their use for enhancing passivation of metal substrates.

The invention belongs to the technical field of organic synthesis, and particularly relates to a universal selective co-production method of monosubstituted alkynyl tertiary alcohol, which comprises the following steps: 1) adding alkali and an organic solvent into a reaction container, replacing air in the reaction container with acetylene gas, and continuously introducing the acetylene gas into the reaction container to keep the acetylene pressure in the reaction container at 0.10-0.25 MPa; 2) stirring and heating to 20-80 DEG C, dropwise adding ketone into the reaction container, and carrying out heat preservation reaction until the reaction is finished; and 3) quenching the reaction liquid, taking an organic phase material, washing, drying, and carrying out rotary evaporation concentration to obtain the target product. Acetylene and ketone are used as raw materials for co-production of the monosubstituted alkynol and the disubstituted alkynol, the yield of the monosubstituted alkynol can reach 24.86% at most, and the method is suitable for various ketone compounds and has good universality, and the process is simple to operate and easy to industrially popularize.

N-Biarylmethylene substituted pyrrolopyridinone, pyrrolopyrazinone, pyrrolopyrimidinone, and isoindolin-1-one compounds having a tertiary alcohol-containing group substituted on the biarylmethylene are positive allosteric modulators of the muscarinic acetylcholine receptor M1 (mAChRM1). The compounds and pharmaceutical compositions may be used in treating neurological disorders, psychiatric disorders, or a combination thereof.

The present application provides a demercaptan agent consisting of: (1) at least one aminocarboxylate salt containing a primary amine group, a secondary amine group or a tertiary amine group, (2) at least one alcohol amine being a primary alcohol amine, a secondary alcohol amine or a tertiary alcohol amine, and (3) water. The present application also provides a preparation method and use of the demercaptan agent and a method for removing mercaptans from liquefied petroleum gas using the demercaptan agent. The demercaptan agent of the present application removes mercaptans by extraction without using inorganic bases such as sodium hydroxide, and the regenerated demercaptan agent can be regenerated by steam stripping, recycled and used, and no alkali residue is discharged. The demercaptan agent of the present application can be used for removing mercaptans from liquefied petroleum gas, and the total sulfur content of refined liquefied petroleum gas can be reduced to 5 μg·g ‑1 The following.

The invention discloses a preparation method and application of a series of novel chiral polydentate amino alcohol ligands. The synthesis method comprises the following steps: preparing primary alcohol type chiral amino alcohol by taking L-amino alcohol and 2-halogenated heteroaromatic ring as raw materials and carrying out nucleophilic substitution reaction in one step; the tertiary alcohol type chiral amino alcohol is prepared by taking L-leucine as a raw material, and sequentially carrying out methyl esterification, Buchwald-Harwig cross-coupling reaction and phenyl magnesium bromide addition reaction to synthesize the tertiary alcohol type chiral amino alcohol. The method disclosed by the invention is simple in process, mild in reaction condition, cheap and easily available in raw materials, easy in product separation and purification and high in yield; and the prepared chiral polydentate amino alcohol ligand can be applied to identification of camphorsulfonic acid enantiomers and determination of enantiomer excess (ee value).

This invention belongs to the field of organic synthesis technology and relates to a method for preparing high-purity tertiary alcohols, comprising: (1) reacting the crude product of the compound shown in Formula I with p-nitrobenzoyl chloride; (2) recrystallizing the obtained product to obtain the compound shown in Formula II; and (3) hydrolyzing and distilling the compound shown in Formula II to obtain the pure product of the compound shown in Formula I, as shown below. The high-purity tertiary alcohol prepared by this method has a single impurity content of less than 0.1% and has been successfully applied to E-nerolidol, with a purity sufficient to meet the requirements for use as a pharmaceutical raw material. This method has high yield, low cost, and is suitable for industrial production.

[Problem] To provide a method for improving the selectivity of an unsaturated aldehyde. [Solution] A method for producing an unsaturated aldehyde, which uses a catalyst including a complex oxide containing molybdenum, bismuth, iron, and cobalt, and subjects a compound selected from propylene, isobutylene, and a tertiary alcohol to catalytic gas-phase oxidation in the presence of a molecular oxygen-containing gas in a fixed-bed multi-tubular reactor, wherein the catalyst is obtained by reduction treatment followed by oxidation treatment.

Disclosed herein are methods for preparing tertiary alcohols from optionally substituted phenyl ketones or optionally substituted pyridyl ketones, the methods comprising the use of chiral ligands and boron trifluoride etherate. The tertiary alcohols can be used to prepare synthetic forms of natural products and / or drugs.

The invention discloses an organic amine composition for capturing CO2 in flue gas, a decarburization solvent containing the composition and a decarburization method of the decarburization solvent, the organic amine composition comprises 2, 4, 6-trisubstituent-1, 3, 5-triazinane and tertiary alcohol amine, and substituent groups are selected from alcohol groups and / or hydroxyl groups. The composition and the decarburization solvent have excellent CO2 absorption performance and CO2 desorption performance when applied to decarburization, and indexes such as CO2 absorption capacity, absorption rate, desorption efficiency and desorption energy consumption can be considered at the same time.

The invention provides a novel method for realizing conversion from tertiary alcohol to ester in one step through carbon-carbon bond oxidative cleavage. According to the method, the ester compound is prepared from the tertiary alcohol compound by reacting for 12-48 hours at 110-180 DEG C in the presence of a nitrate catalyst in an oxygen atmosphere, and the method has the following advantages: 1) the application range of a substrate is wide, and the yield of medium or above can be obtained; and 2) the method does not need additional addition of an initiator, an oxidant and the like, and has the advantages of simplicity in operation, high stability, capability of realizing gram-level scale amplification and the like. And 3) the method can realize functional group conversion of complex bioactive molecules.

The present invention discloses a polymerizable compound, a liquid crystal composition comprising the polymerizable compound, and a liquid crystal display device. The polymerizable compound is a compound represented by the following formula I, wherein Sp represents a single bond or a C1-C5 linear, branched or cyclic alkyl group, and the Sp groups are not both single bonds, wherein any one or more non-adjacent —CH2— can be replaced by —O—, —S—, —CO—, —CH2O—, —OCH2—, —COO—, —OOC—, or an acrylate group in such a manner that O- or S-atoms are not directly connected with each other, one or more H atoms can be independently replaced by F, C1, or G3, and at least one H atom is replaced by G3; G3 represents a C1-C7 tertiary alcohol structure; and X represents —CH2—, —O—, or —S—. In particular, the polymerizable compound has the advantages of good diffusivity, high stability of the formed polymer, and low residue after a UV process. It can be ensured that a display exhibits excellent IS performance under extreme conditions.

The invention belongs to the technical field of organic synthesis, and particularly relates to a method for tubular production of monosubstituted alkynyl tertiary alcohol, which comprises the following steps: 1) in an oxygen-free environment, adding magnesium chips and an initiator into an organic solvent, stirring and heating to 30-50 DEG C, adding an organic solution of halogenated alkane, and reacting for 25-50 minutes to obtain an alkyl magnesium halide mixed solution; 2) in an oxygen-free environment, continuously introducing acetylene gas into the organic solvent, dropwise adding the alkyl magnesium halide mixed solution into the organic solvent, reacting at 30-60 DEG C to obtain an ethynyl magnesium halide mixed solution, and stopping introducing the acetylene gas; and 3) in an oxygen-free environment, dropwise adding an organic solution of ketone into the ethynyl magnesium halide mixed solution which is heated to 45-60 DEG C, continuously reacting for 1-3 hours after dropwise adding is finished, and adding an acidic compound for quenching to obtain a target product. The monoalkynol with different structures is prepared by the same method, the whole process adopts a closed series process, intermediate products do not need to be treated, the process flow is simple, the safety is relatively high, the process production cost can be reduced, and the like, and industrial production is facilitated.

The present invention provides a polyurethane resin composition that exhibits excellent compatibility between hydroxyl group-containing compounds and crosslinking agents, and in which the cured product can exhibit hardness, elongation, and tensile strength suitable for following stress changes in parts, as well as excellent moisture resistance. [Solution] A polyurethane resin composition containing (A) an isocyanate group-containing compound, (B) a hydroxyl group-containing compound, and (C) a crosslinking agent, The (C) crosslinking agent comprises a secondary alcohol group and / or a tertiary alcohol group. The crosslinking agent (C) has a number average molecular weight of 900 or less. A polyurethane resin composition characterized by the following features.

Disclosed herein are methods for preparing tertiary alcohols from an optionally substituted phenyl ketone or an optionally substituted pyridinyl ketone that includes the use of a chiral ligand and boron trifluoride diethyl etherate. Tertiary alcohols can be used to prepare synthetic versions of natural products and / or pharmaceuticals.

The present invention aims to provide a means for imparting adhesiveness to nails even without polishing. The present invention is a nail primer resin composition containing (A) and (B) components and not containing a photoradical initiator, the (A) component: at least one selected from the group consisting of a secondary alcohol having a (meth)acryl group and a molecular weight of 145 or more, and a tertiary alcohol having a (meth)acryl group and a molecular weight of 145 or more (wherein the (B) component is excluded); and the (B) component: a phosphate ester compound having a (meth)acryl group.