329 results about "Boron trifluoride" patented technology

The invention discloses a boron trifluoride purification device and a boron trifluoride purification method, and relates to the technical field of boron trifluoride purification. The boron trifluoride purification device comprises an adsorption tower, the side face of the adsorption tower is connected with a material mixing tower through a pipeline, the side face of the material mixing tower is connected with a light component removal tower through a pipeline, and the side face of the light component removal tower is connected with a heavy component removal tower through a pipeline. The side surfaces of the light component removal tower and the heavy component removal tower are connected with a three-waste treatment bin through pipelines. The boron trifluoride purification method comprises the steps that after gas is introduced into the mixing tower, a servo motor is started, and a rotating cylinder, a rotating disc, a torsional spring, an extrusion block, a fixing block, a hydraulic device, a first stress rod, an arc-shaped rod, a first spring, a rotating block and a mixing plate are matched, so that the residence time of the gas in the mixing tower can be prolonged when needed, and the mixing effect of the device is improved.

To provide a fluorine substituent-containing hydrocarbon resin polymer having excellent electric performance, and production method of the same, and a substrate structure including a resin layer formed by cross-linking a resin composition including the hydrocarbon resin polymer.SOLUTION: A hydrocarbon resin polymer including a repeating unit (A) is derived from dicyclopentadiene (DCPD). The hydrocarbon resin polymer has a fluorine substituent where a content of the fluorine substituent is 100-4,500 ppm. A production method of the hydrocarbon resin polymer includes a step of polymerizing a mixture in the presence of a fluorine-containing compound, where the fluorine-containing compound is a boron trifluoride complex, and the mixture includes dicyclopentadiene. A substrate structure includes a resin layer, and a conductive layer disposed on the resin layer. The resin layer is formed from a resin composition including the hydrocarbon resin polymer using a cross-linking process.SELECTED DRAWING: Figure 2

The invention relates to the technical field of trimethyl boron preparation, in particular to a high-purity trimethyl boron preparation method which comprises the following steps: S1, reaction raw material preparation: magnesium powder and methane chloride react to generate methylmagnesium chloride; reacting boron trifluoride with aluminum trichloride to generate boron trichloride; s2, taking methyl magnesium chloride and boron trichloride as raw materials, and carrying out dry reaction under the conditions that the pressure is 0-1.0 MPa and the temperature is 40-150 DEG C to generate crude trimethyl boron and magnesium chloride; s3, the crude trimethyl boron is subjected to condensation, adsorption and two-stage rectification in sequence, and a high-purity trimethyl boron product is obtained; and S4, magnesium chloride is electrolyzed to obtain magnesium powder and chlorine, and the magnesium powder and the chlorine are recycled. Compared with the prior art, the method has the advantages that the trimethyl boron is prepared by adopting the dry reaction, the reaction is more sufficient, the reaction efficiency is high, the crude trimethyl boron product is purified, the product purity is improved, in addition, the byproduct magnesium chloride can be recycled, and the resource waste is reduced.

The invention relates to a preparation method of lithium fluoroborate containing unsaturated bonds, and belongs to the technical field of lithium ion battery additives. The preparation method comprises the following steps: carrying out reaction on organic acid lithium containing unsaturated bonds and boron trifluoride gas in a solvent at a low temperature of-10 to 0 DEG C, and carrying out solid-liquid separation to obtain a lithium fluoroborate crude product containing unsaturated bonds; the solvent is a poor solvent of lithium fluoroborate containing unsaturated bonds. According to the method, boron trifluoride gas is used as a fluorine reagent, so that introduction of water is avoided; the method has the advantages of simple operation, high product quality, high yield, low cost, full utilization of raw materials, reduction of the generation of three wastes, and suitableness for large-scale production. The yield of the obtained product can reach 96% or above, and the purity can reach 99% or above.

The invention belongs to the technical field of electrochemical energy storage, and particularly relates to a battery capable of supplementing lithium or sodium in situ, which comprises a positive plate, a negative plate and an electrolyte, and is characterized in that the electrolyte contains a component A, and a positive electrode and / or a negative electrode contains a component B; the structural general formula of the component A is X-Y, and X is lithium fluorosulfonate, sodium fluorosulfonate, lithium difluorophosphate or sodium difluorophosphate; y is boron trifluoride or phosphorus pentafluoride; the component B is at least one of lithium oxalate, sodium oxalate, lithium fluoride and sodium fluoride. Compared with the prior art, the component A and the component B are simultaneously added into the battery disclosed by the invention, so that the battery shows more excellent cycle performance and high-temperature performance. The combination mode has better performance compared with the mode that the component B is independently used in the electrode material or the component A is independently used in the electrolyte.

The present invention provides a chemical synthesis method of EPS-G7, wherein β-cyclodextrin A is acetylated to obtain β-acetylcyclodextrin B, B is ring-opened in a mixed solution of acetic anhydride / concentrated sulfuric acid to obtain a chain acetylated heptose C, p-nitrophenol is condensed with intermediate C using boron trifluoride acetonitrile to obtain a key intermediate p-nitrophenyl (G1)-O-acetyl-D-maltoseptaglycoside D with α as the dominant configuration, D is removed from the acetyl group under the action of sodium methoxide to obtain pNP-G7 (p-nitrophenyl (G1)-D-maltoseptaglycoside), pNP-G7 is in the presence of p-toluenesulfonic acid and dimethoxyethane, and acetal protection is formed between the hydroxyl groups on C4 and C6 of the terminal monosaccharide to obtain EPS-G7. The reaction raw materials used in the method of the present invention are cheap and readily available, and the chemical synthesis of α-amylase detection reagent EPS-G7 is realized, which is a simple, economical and efficient synthesis method.

The invention discloses an electrolyte with high and low temperature performance under high voltage and a lithium ion battery. The electrolyte comprises a first additive and a second additive, the first additive at least comprises pyrosulfate boron trifluoride composite lithium salt with a structure shown in a formula (I-1): # imgabs0 #, a cyclic sulfonate compound serving as a second additive and oxalate lithium salt serving as a third additive, and the first additive, the second additive and the third additive respectively account for a%, b% and c% of the total mass of the electrolyte, the following relational expressions are met: 0.2 < = b + c < = 4; 0.2 < = b / c < = 10; 0.07 < = (b + c) / a < = 20. The electrolyte is used for the lithium ion secondary battery, the battery impedance can be reduced under the high voltage larger than or equal to 4.3 V, meanwhile, high-temperature storage gas production of the battery is restrained, and the high-temperature performance and the low-temperature performance of the battery are improved.

The invention relates to a preparation method of a polyester film based on full-hydroxyl column [5] arene. The polyester film with salt separation is prepared by taking full-hydroxyl column [5] arene as a water-phase monomer through an interfacial polymerization method. The method comprises the following steps: (1) synthesizing methoxy pillar [5] arene from 1, 4-dimethoxybenzene and paraformaldehyde under the catalysis of boron trifluoride diethyl etherate; (2) reacting the purified product with boron tribromide, and removing methyl groups to obtain full-hydroxyl column [5] arene; (3) dissolving the product in an aqueous solution containing triethylamine, and forming a two-phase solution of interfacial polymerization reaction with an n-hexane solution of trimesoyl chloride; and (4) sequentially coating the surface of the polyacrylonitrile ultrafiltration membrane with the aqueous phase solution and the organic phase solution, and carrying out interfacial polymerization reaction to obtain the polyester membrane. Based on the inherent cavity and polyhydroxy characteristics of the full-hydroxyl column [5] arene, compared with a traditional polyamide membrane, the obtained polyester membrane has high permeability and selectivity, can efficiently separate dye and inorganic salt, and is suitable for water treatment processes of printing and dyeing wastewater and the like.

The invention discloses a preparation process of a cefpodoxime mother nucleus 7-AMCA, and relates to the technical field of 7-AMCA. According to the technical scheme, the method comprises the following steps: adding dimethyl carbonate and a boron trifluoride-dimethyl carbonate complex into a reaction bottle A, and dropwise adding an alkylation reagent; adding D-7ACA, and reacting at room temperature; adding purified water, sodium pyrosulfite and edetate disodium into the reaction bottle B; transferring the feed liquid in the reaction bottle B into a reaction bottle A, adding an organic solvent into the mixed liquid at room temperature, and extracting and separating the liquid to obtain a water phase; dropwise adding an alkaline solution into the water phase, adjusting the pH value to 2.8-3, and cooling to grow crystals; dropwise adding an alkaline solution, adjusting the pH value to 4.5-5.2, and cooling to grow crystals; and filtering out mother liquor, washing to be colorless, leaching by using an organic solvent, pumping, and drying in vacuum to obtain the cefpodoxime mother nucleus 7-AMCA. According to the invention, D-7ACA is taken as a starting raw material, the process flow is improved, the preparation process of 7-AMCA is optimized, and the purposes of improving the product quality and increasing the yield are achieved.

The present invention provides a preparation method of lithium difluorooxalate borate, belonging to the technical field of lithium battery electrolyte additives. The present invention obtains a bis(methylsilyl) oxalate compound by a substitution reaction between a methylchlorosilane compound and oxalic acid, and mixes the bis(methylsilyl) oxalate compound with lithium oxalate, a boron trifluoride complex and an organic solvent to obtain lithium difluorooxalate borate; wherein the bis(methylsilyl) oxalate compound is used as a raw material, has strong reaction activity, generates a stable methylfluorosilane gas byproduct while introducing oxalate into the system, and does not cause chloride ions and free acid residues; in addition, when the raw material is bis(trimethylsilyl) oxalate, even if there is a small amount of raw material residue, it can be used as a new multifunctional electrolyte additive, play a certain synergistic role, and can improve the compatibility between electrolytes. The whole process is simple, the product yield obtained by the reaction is high, the product purity is high, and the separation is easy, which is suitable for industrial production.

The invention relates to preparation of a cefazolin compound, in particular to a preparation method of a cefazolin acid three-position intermediate TDA. The preparation method comprises the following steps: carrying out condensation reaction on 7-ACA and MMTD serving as raw materials, dimethyl carbonate serving as a solvent and a boron trifluoride dimethyl carbonate complex and glacial acetic acid serving as catalysts to obtain condensation reaction liquid; adding EDTA (Ethylene Diamine Tetraacetic Acid) and sodium pyrosulfite into water, carrying out stirring reaction, transferring the condensation reaction liquid into water, and continuously carrying out heat-preservation stirring, so as to obtain a hydrolysis reaction liquid; and adding a sodium carbonate solution into the hydrolysis reaction solution while stirring, adjusting the pH value, growing crystals, and then performing suction filtration, washing and drying to obtain a finished product. A boron trifluoride dimethyl carbonate complex-glacial acetic acid catalysis method is adopted, the product quality and yield are guaranteed in industrial production, meanwhile, the reagent usage amount and the waste liquid generation amount are reduced, the production cost and the environment pressure are reduced, normal reaction is maintained at normal pressure, and the reaction is prevented from being too severe.

The invention discloses an expandable rubber cable pipe plugging device and a preparation method thereof.The expandable rubber cable pipe plugging device is prepared from, by weight, 100 parts of EPDM rubber, 0.5-1.0 part of graphene, 0.2 part of silane coupling agent KH550, 10 parts of sodium carboxymethyl cellulose, 15 parts of sodium acrylate-acrylamide copolymer, 5 parts of polyvinyl alcohol, 8 parts of bentonite, 5 parts of expandable graphite and 3 parts of 4, 4 '-oxybisbenzenesulfonyl hydrazide foaming agent. The anti-aging coating is prepared from the following components in parts by weight: 1 part of zinc stearate, 2.5 parts of peroxide DCP, 2 parts of assistant crosslinker TAIC, 5 parts of zinc oxide, 1 part of stearic acid, 30 parts of fumed silica, 5 parts of modified nano montmorillonite, 20 parts of light calcium carbonate, 1.5 parts of anti-aging agent TMQ, 1 part of anti-aging agent 6PPD, 0.5 part of hindered phenol antioxidant 1076, 2 parts of UV absorbent UV-3292, 8 parts of naphthenic oil, 10 parts of microcapsules and 0.5 part of boron trifluoride diethyl etherate complex catalyst.

The invention provides a high-quality boron isotope separation process and device, the device comprises an exchange rectification system, a complexing system, a complex cracking system and a boron-11 refining system, natural abundance boron trifluoride isotopes are separated through an exchange rectification tower, and cyclic regeneration of boron trifluoride and anisole is realized by adopting the complexing system and the cracking system. A boron-11 refining system is arranged to further improve the abundance of boron-11. According to the method, the industrial continuous production of the high-quality boron trifluoride-10 with the abundance of 99% and the high-quality boron trifluoride-11 with the abundance of 99.9% can be synchronously realized, the process is simple and clear, and the operability is high.

The present invention provides a paroxysmal hemoglobinuria indication drug ipropam key intermediate synthesis method, and relates to the technical field of ipropam, the method comprises: taking p-bromobenzaldehyde as an initial raw material, adopting an S-configuration catalyst to obtain an intermediate 03, carrying out protection group removal on the intermediate 03, carrying out automatic ring closing to obtain an intermediate 04, and carrying out post-treatment to obtain the paroxysmal hemoglobinuria indication drug ipropam key intermediate. Reducing the intermediate 04 with sodium borohydride to obtain a single cis-configuration intermediate 05, then carrying out a chiral flip reaction and hydrolysis to remove p-nitrobenzoic acid, then carrying out an etherification reaction with diethyl sulfate to obtain an intermediate 08, reducing amide of the intermediate 08 with sodium borohydride and boron trifluoride diethyl etherate to obtain an intermediate 09, then carrying out an acetylation reaction to protect amino, and finally carrying out a reaction to obtain the chiral cis-configuration intermediate 03. Cuprous cyanide is subjected to a cyanation reaction and a hydrolytic esterification reaction to obtain the ipropam key intermediate TM. The method is low in raw material price, high in chiral control selectivity, easy in reaction condition control and low in equipment requirement, avoids column chromatography and other operations, and is more suitable for industrial production.

The invention discloses an epoxy resin material for electronic plastic package of a radio frequency chip and a preparation method of the epoxy resin material. The preparation method comprises the following steps: firstly, carrying out alkylation reaction on dicyclopentadiene and phenol in the presence of a catalyst boron trifluoride diethyl etherate to synthesize dicyclopentadiene phenol resin, and epoxidizing the dicyclopentadiene phenol resin through epoxy chloropropane to obtain dicyclopentadiene epoxy resin DCPDDE; then, synthesizing a poly (dicyclopentadiene) linear polymer PDCPD by taking a Pd / Ag ionic compound as a catalyst, and then reacting the PDCPD with cysteamine sulfydryl to obtain dicyclopentadiene cysteamine PDCPDAm; and finally, mixing the DCPDDE, the PDCPDAm, the filler and the coupling agent, stirring, defoaming and curing to form the thermosetting resin with a three-dimensional network structure. The synthetic process is simple, the cost is low, the mobility and polarizability of molecules are limited due to high rigidity and low polarity of the obtained resin, transmission of a radio frequency chip under a high-frequency high-speed signal is ensured, stable operation in a complex working environment is ensured, reliable packaging protection is provided for the radio frequency chip, and the service life of the radio frequency chip is prolonged. And the thermal stability and the low dielectric property of the radio frequency chip are improved to the greatest extent.

A problem to be addressed by the present invention is to provide a carbon fiber bundle capable of efficiently transiting the tensile strength of the fiber to a carbon fiber-reinforced composite material formed using the carbon fiber bundle, the carbon fiber bundle including a sizing agent added thereto, wherein the tensile strength of resin-impregnated strands (tensile strength A' of resin-impregnated strands) of the carbon fiber bundle is 5.0 GPa or more and 6.0 GPa or less, as evaluated on the basis of JIS R7608 (2007) using Resin Formulation A below; wherein the tensile strength of resin-impregnated strands (tensile strength B' of resin-impregnated strands) of the carbon fiber bundle is 4.7 GPa or more and 5.5 GPa or less, as evaluated on the basis of JIS R7608 (2007) using Resin Formulation B below; wherein the ratio of the tensile strength B' of resin-impregnated strands to the tensile strength A' of resin-impregnated strands is 85% or more; and wherein the single-fiber diameter of the carbon fiber bundle is 6.0 µm or more; Resin Formulation A: "CELLOXIDE (registered trademark)" 2021P, boron trifluoride monoethyl amine, and acetone are used at a ratio of 100:3:4 (parts by mass), and the curing conditions of a normal pressure, a temperature of 125°C, and a time of 30 minutes are used; and Resin Formulation B: "JER (registered trademark)" 828, dicyandiamide, and 3-(3,4-dichlorophenyl)-1,1-dimethylurea are used at a ratio of 100:6.3:2 (parts by mass), and the curing conditions of a normal pressure, a temperature of 130°C, and a time of 90 minutes are used.

The invention discloses a preparation method of liquid lithium tetrafluoroborate, which comprises the following steps: fluorating anhydrous lithium chloride by anhydrous hydrogen fluoride in an organic solvent to obtain lithium fluoride, then introducing boron trifluoride gas or adding a boron trifluoride complex, and reacting to obtain a lithium tetrafluoroborate liquid; the preparation process is simple and efficient, the adopted raw materials are very easy to obtain, meanwhile, the fluorination reaction and the lithium tetrafluoroborate synthesis reaction are sequentially carried out in an organic solvent environment, the whole reaction process is safe, stable and reliable, and the preparation method is very suitable for large-scale batch popularization and application; and the lithium tetrafluoroborate liquid with a low acid value can be directly obtained and can be directly applied as an electrolyte additive.

The invention relates to the technical field of organic functional material synthesis and mycotoxin removal, in particular to a magnetic covalent organic framework for adsorbing zearalenone and a preparation method and application thereof.The magnetic covalent organic framework is Fe3O4 (at) COF-VPBA and is prepared from 1, 3, 5-tris (4-aminophenyl) benzene, 2, 5-dimethoxy terephthalaldehyde, 4-alkenyl phenylboronic acid, boron trifluoride diethyl etherate, 2, 3-dichloro-5, 5-di (4-aminophenyl) benzene, 2, 5-dimethoxy terephthalaldehyde, 2, 5-dimethoxy terephthalaldehyde, 2, 5-dimethoxy terephthalaldehyde, 2, 5-dimethoxy terephthalaldehyde, 2, 5-dimethoxy terephthalaldehyde, 2, 5-dimethoxy terephthalaldehyde, 2 The catalyst is prepared from 2, 6-dicyano-1, 4-benzoquinone and nano ferroferric oxide through a four-component one-pot in-situ Povarov reaction. According to the method, the process is simplified, the defects of a fractional step method are avoided, due to specific covalent binding of boric acid groups and ZEN catechol hydroxyl groups, the adsorption capacity and the adsorption rate are remarkably superior to those of traditional and unfunctionalized adsorption materials, the adsorption rate still exceeds 90% after acetonitrile is eluted and regenerated and is repeatedly used for more than 5 times, and the comprehensive requirements of high selectivity, high adsorption capacity, easiness in separation and recyclability are met.

The invention relates to a synthesis method of 5, 5-disubstituted 2-isoxazoline, according to the method, oxime of a formula (II) and a carbonyl compound of a formula (I) react in the presence of a boron trifluoride complex and in the presence of an optional organic solvent or no solvent, the reaction conditions are mild, and the product yield is high.

The invention provides a preparation method of high-purity lithium difluoro (oxalato) borate, which comprises the following steps: taking a boron trifluoride complex, lithium oxalate and anhydrous oxalic acid as raw materials, simultaneously adding a composite catalyst prepared from polyaluminum chloride and silicon dioxide gel, filtering, concentrating, evaporating and crystallizing, washing and drying to obtain a lithium difluoro (oxalato) borate product. The yield of the lithium difluoro (oxalato) borate obtained by the method can reach 90% or above, and the purity of the lithium difluoro (oxalato) borate can reach 99.65% or above; meanwhile, the composite catalyst disclosed by the invention can be repeatedly utilized, and high-yield and high-purity lithium difluoro (oxalato) borate can also be obtained.

The invention discloses a phototherapy reagent and a preparation method and application thereof. The preparation method comprises the following steps: 1-[4-(diethylamino) phenyl]-ethane-1-ketone and 4-methoxybenzaldehyde are subjected to a condensation reaction in a NaOH ethanol solution, and a product and nitromethane are subjected to addition; performing condensation and addition on the other groups of raw materials by the same method; cyclizing the two addition products with ammonium acetate, and coordinating with boron trifluoride diethyl etherate to obtain NHM; carrying out substitution reaction on the NHM and sodium nitrite to obtain NOO; and oxidizing NOO by m-chloroperoxybenzoic acid to obtain NNOO. The reagent can target a tumor hypoxia microenvironment, hypoxia monitoring is achieved, NO is released through photostimulation for tumor gas therapy, meanwhile, the secondary amplification photo-thermal therapy effect is achieved, preparation is controllable, diagnosis and treatment are integrated, and the reagent is sensitive, safe and suitable for biomedical research and clinical diagnosis.

The invention relates to a continuous production method of ultra-pure 2, 3, 4, 4 '-tetrahydroxybenzophenone, which comprises the following steps: completely dissolving p-hydroxybenzoic acid in high-boiling range petroleum ether, and completely dissolving pyrogallic acid in the high-boiling range petroleum ether; the preparation method comprises the following steps: adding a p-hydroxybenzoic acid solution and a pyrogallic acid solution into an ultra-pure continuous reactor group, adding boron trifluoride diethyl etherate into the ultra-pure continuous reactor group at a flowing speed, reacting at 110-140 DEG C, adding the obtained reaction solution into the next ultra-pure continuous reactor group, stirring in ice water, filtering, washing and recrystallizing to obtain the 2, 3, 4, 5-tetramethyl-3, 5-dihydroxybenzoic acid. According to the present invention, the reaction time is substantially shortened, the conversion rate is 70-80%, the purity of the obtained electronic product is more than or equal to 99.2%, the content of the metal ions such as sodium, aluminum, copper, iron, calcium, zinc and boron is less than or equal to 60 ppb, the reaction materials, the reaction temperature and the reaction rate are controllable, the reaction is sufficient, the yield of the obtained target product is stable, and the method can be used for continuous production.

The invention relates to a catalytic hydrolysis method of waste epoxy resin, which comprises the following steps: putting the waste epoxy resin into a reaction kettle, adding ultrapure water, adding a small amount of sodium dodecyl diphenyl ether disulfonate surfactant and a boron trifluoride acetic acid catalyst, and carrying out hydrolysis reaction to realize catalytic degradation of the epoxy resin. Degradation products can be converted into epoxy monomers and anhydride monomers, so that cyclic utilization is realized. Compared with the prior art, the degradation method provided by the invention is not only green and safe, but also high in degradation efficiency, solves the problem that the waste epoxy resin cannot be recycled, saves resources, meets the green development requirement, and has practical engineering application value.

The invention discloses a graphene-containing carrier material, a negative pressure container containing the same and used for storing electronic gas, and a use method and a preparation method of the graphene-containing carrier material. The negative pressure container comprises a bottle body, a valve and a carrier material filled in the bottle body, and the carrier material comprises graphene. By utilizing the characteristics that the selected carrier material has a relatively high specific surface area and a relatively large pore volume, the whole negative pressure container is filled with the carrier material so as to load and unload electronic gases including arsine, phosphorane, boron trifluoride and the like, and excellent loading capacity and unloading capacity are shown; the product type of the negative pressure container capable of containing the electronic gas is expanded, and the benign development of the negative pressure container market is guaranteed.

The present invention belongs to the technical field of synthesis of genipin derivatives, and specifically relates to a method for preparing a 1-O-alkyl genipin derivative. The present invention mixes genipin, a low-carbon alcohol, a catalyst and a polar organic solvent for alkoxylation reaction; the catalyst is fluoroboric acid or a mixture of fluoroboric acid and boric acid or a mixture of boron trifluoride etherate and water; when the catalyst is fluoroboric acid or a mixture of fluoroboric acid and boric acid, the temperature of the alkoxylation reaction is ≥rt; when the catalyst is a mixture of boron trifluoride etherate and water, the temperature of the alkoxylation reaction is ≥0°C. The preparation method provided by the present invention can achieve 1-O-alkyl genipin derivatives with high R configuration selectivity under mild reaction temperature conditions by selecting fluoroboric acid or a mixture of fluoroboric acid and boric acid or a mixture of boron trifluoride etherate and water as a catalyst for alkoxylation reaction, and the preparation method is simple, the reaction conditions are mild, and it is more suitable for industrial production.

The invention provides a device and a method for on-line measurement of boron concentration in a boron trifluoride complex system, and relates to the technical field of boron-10 acid production. The device comprises a neutron emission part, a fluid circulation part, a neutron detection part and a data processing part. The neutron emission part is used for emitting thermal neutron beams, the fluid circulation part is communicated with a fluid pipeline at the bottom of an exchange rectifying tower of the boron trifluoride-anisole complex production process, and the fluid circulation part is of a neutron penetrable structure; the neutron detection part is arranged on the side, away from the neutron emission part, of the fluid circulation part and used for receiving thermal neutron beams penetrating through the boron trifluoride-anisole complex and converting neutron intensity signals into electric signals, and the data processing part is electrically connected with the neutron detection part and used for receiving the electric signals and sending the electric signals to the fluid circulation part. And inverting the concentration of boron-10 in the boron trifluoride-anisole complex according to the attenuation degree of the thermal neutron beam to obtain the total concentration of boron. The device can output the total boron concentration measurement result in real time, and sampling can be carried out without interrupting the production process.

The present invention relates to the technical field of the preparation of macrocyclic compounds, specifically a preparation method and application of a novel fluorescent macrocyclic compound. The preparation method synthesizes a dialdehyde-substituted intermediate through a Suzuki coupling reaction; the obtained intermediate is reduced to benzyl alcohol and then converted into benzyl chloride; benzyl chloride and 1,4-bis(bromomethyl)benzene are subjected to a Friedel-Crafts reaction to obtain a monomer; under the catalysis of boron trifluoride diethyl ether, the monomer is cyclized to obtain a bromine-chain-substituted macrocyclic compound; the bromine-chain-substituted macrocyclic compound reacts with trimethylamine in ethanol to obtain a water-soluble fluorescent macrocyclic compound. By designing and synthesizing the novel fluorescent macrocyclic compound, the present invention can generate singlet oxygen in vitro, effectively encapsulate antibacterial drugs, and perform bacterial imaging at the same time. Through the synergistic effect, the macrocyclic compound enhances the efficacy of antibacterial drugs, overcomes the problems of drug resistance and reduced drug efficacy of traditional antibacterial agents, and provides a new strategy for antibacterial treatment.

The invention relates to a method for producing polyacetal resin. Provided is a method for producing a polyacetal resin with which it is possible to stably and continuously produce a polyacetal resin over a long period of time while suppressing the generation of a tar-like precipitate caused by a polymerization catalyst. A method for producing a polyacetal resin, characterized by comprising a polymerization step in which a polymerization reaction is carried out using (a) a cyclic ether and / or a cyclic formal containing at least trioxymethylene, (b) boron trifluoride or a boron trifluoride complex, and (c) an organic solvent. And the organic solvent (c) is a compound represented by a predetermined formula (1).

The invention discloses a ginseng extract, a preparation method and application of the ginseng extract in whitening, skin tendering and wrinkle removing products. A used whitening skin care product is mainly diglucosyl gallic acid containing ginseng powder, firstly, cyclic gamma-polyglutamic acid resin is synthesized, the resin has a good aperture structure, then the synthesized cyclic gamma-polyglutamic acid resin is added into the diglucosyl gallic acid to modify the diglucosyl gallic acid, the resin has good biocompatibility, and therefore the skin care effect is good. The hydrophilicity and the stability of the protein can be improved. Meanwhile, based on unique properties of American ginseng, the American ginseng is modified, ground and added into diglucosyl gallic acid; the diglucosyl gallic acid is synthesized by acetylation reaction, namely methyl gallate and alpha-penta-acetyl glucose are added into mixed xylene, a boron trifluoride diethyl etherate complex is used as a catalyst, penta-acetyl glucose is added and introduced into phenolic hydroxyl of methyl trihydroxybenzoate, and the diglucosyl gallic acid is synthesized by the reaction of alpha-penta-acetyl glucose, alpha-penta-acetyl glucose and alpha-penta-acetyl glucose. And salifying, acidifying and separating to obtain the diglucosyl gallic acid.

The invention discloses a preparation method of 3-((1r, 3r, 5r, 7r)-adamantane-2-yl) propiolic acid. The preparation method provided by the invention comprises the following steps: (1) taking adamantanone as a starting raw material, and carrying out French reaction to prepare a compound 2; (2) the compound 2 is subjected to a dehydroxylation reaction under the action of boron trifluoride diethyl etherate and triethyl silane, and a compound 3 is prepared; and (3) carrying out hydrolysis reaction on the compound 3 under the action of LiOH to obtain a target product, namely 3-((1r, 3r, 5r, 7r)-adamantane-2-yl) propiolic acid. The preparation method disclosed by the invention is short in process route, simple and convenient to operate, mild in reaction condition, easy to control, high in yield, few in by-products, relatively low in cost and suitable for process amplification.