49 results about "Metalation" patented technology

Metalation (Alt. spelling: Metallation) is a chemical reaction which involves the bonding of a metal atom to what is typically an organic molecule to form a new compound. This reaction usually involves the replacement of a halogen atom in an organic molecule with a metal atom to form an organometallic compound. In the laboratory, metalation is commonly used to activate organic molecules during the formation of C—X bonds (where X is typically Carbon, Oxygen, or Nitrogen), which are necessary for the synthesis of many organic molecules.