44results about "Diaryl/thriaryl methane dyes" patented technology

The invention provides a triarylmethane dye and application thereof, and particularly provides a triarylmethane dye, a coloring composition and an optical filter. By designing the structure of the triarylmethane dye, the triarylmethane dye with excellent performance is obtained, and the triarylmethane dye has high thermal stability.

The invention discloses a triarylmethane type I photosensitive dye as well as a synthesis method and application thereof. The structure of the dye is shown as a general formula I; intramolecular charge separation is optimized by regulating substituent groups, and the generation efficiency of superoxide anions and hydroxyl radicals is remarkably improved. According to the synthesis method, 4-diphenylaminobenzaldehyde or 4-vinyl benzaldehyde is used as a raw material, efficient preparation is achieved through the steps of condensation, oxidation and the like, the raw material is easy to obtain, and operation is easy and convenient. The dye has strong absorption at the wavelength of 600-630 nm, is suitable for red light triggered photodynamic therapy (PDT), especially keeps high reactive oxygen yield under the hypoxic condition, and breaks through the oxygen dependence limitation of traditional PDT. Experiments show that the dye can induce ferroptosis of tumor cells, has the functions of fluorescence imaging and treatment, and has wide application prospects in the fields of antitumor drugs, in-vivo fluorescence labeling, photoresponsive functional preparations and the like.

To provide a colored resin composition capable of forming a color filter that exhibits excellent brightness and contrast.SOLUTION: The colored resin composition comprises at least one acid selected from the group consisting of a phenylphosphonic acid and a diphenylphosphonic acid each of which may have a substituent, a colorant, a dispersant, and a resin, wherein the colorant comprises a compound represented, for example, by the following formula and the dispersant has an amine value from 0 mgKOH / g to 65 mgKOH / g inclusive.SELECTED DRAWING: None

The present invention relates to a process for preparing a compound corresponding to the formula, this process being characterized in that it comprises at least one oxidation step of sulfonated triphenylmethane of formula [Chem V] with a quinone selected from 1,4-benzoquinone, 1,2-benzoquinone, a dialkyl(C1-C4) 1,4-benzoquinone, a dialkyl(C1-C4) 1,2-benzoquinone, a monoalkyl(C1-C4) 1,4-benzoquinone, a monoalkyl(C1-C4) 1,2-benzoquinone. Novel crystalline form of Patent Blue, sodium salt.

To provide: a triarylmethane dye excellent in heat resistance; and a coloring agent for a color filter having favorable color characteristics by means of a colored composition using the dye.SOLUTION: The invention provides: a triarylmethane dye represented by the general formula (1) in the figure; a colored composition containing the dye; a coloring agent for a color filter; and a color filter. (In the formula (1), R1 to R4 each represent H, an alkyl group, or an aromatic hydrocarbon group; R5 and R6 each represent H, a halogen atom, OH, CF3, NO2, CN, an alkyl group, an alkoxy group, or an aryloxy group; AH represents a heterocyclic group; An represents an anion; and m represents a natural number.)SELECTED DRAWING: None

To provide a color filter excellent in light resistance.SOLUTION: A color filter according to the present invention includes pigment and binder, and has chloride ion content of 10 ppm or more and 400 ppm or less.SELECTED DRAWING: None

The invention provides a compound containing a triarylmethane structure and application thereof, and belongs to the technical field of dye materials. The organic compound with excellent performance is prepared by designing the molecular structure of the compound containing the triarylmethane structure. The compound containing the triarylmethane structure has the characteristics of high brightness, high contrast ratio and high solvent resistance, and can be used as a coloring agent for preparing a liquid crystal display screen.

Revealed is a coolant composition for a vehicle, with excellent color stability and corrosion resistance.

The invention relates to the technical field of organic synthesis, in particular to a preparation method and application of 2-[4-(dihexylamino)-2-methoxybenzoyl] benzoic acid. Comprising the following steps: reacting N, N-dihexyl-3-methoxyaniline with phthalic anhydride in an aprotic solvent by taking Lewis acid as a catalyst, so as to obtain the 2-[4-(dihexylamino)-2-methoxybenzoyl] benzoic acid. By adopting the preparation method disclosed by the invention, high-yield (more than or equal to 88.35%) and high-purity (more than or equal to 99.32%) synthesis of 2-[4-(dihexylamino)-2-methoxybenzoyl] benzoic acid is realized; compared with an existing nucleophilic acyl substitution-hydrolysis method, the yield is 55.62%, and the purity is 75.85%, the yield is improved by 32.73%, and the purity is improved by 23.74%; compared with an existing transition metal catalysis-oxidation method with the yield of 64.94% and the purity of 80.85%, the yield is improved by 23.41%, and the purity is improved by 18.47%.

Provided are tissue regeneration wound treatments, methods of producing the tissue regeneration wound treatments, and methods of treating wounds using the tissue regeneration wound treatments. The tissue regeneration wound treatments include a skin substitute and a colorant applied to the skin substitute. The colorant is a biocompatible colorant that degrades upon attack by proteases within the treated wound.

The present disclosure provides a novel method of amplifying and sequencing L-form polynucleotide. Further provided include L-form nucleotides and D-form enzymes that can be used in the method. The method of making the L-form nucleotides and D-form enzymes are also provided.

The invention relates to a triarylmethane dye and application thereof, and belongs to the technical field of dye compounds. By designing the structure of the triarylmethane dye, the dye compound with relatively good thermal stability and relatively high transmittance is obtained, and the optical filter prepared from the triarylmethane dye has excellent comprehensive performance.

The present disclosure relates to compositions, kits, and methods for in situ synthesis of Schiff reagents, i.e., directly on a substrate, for example, in a liquid pool disposed on the surface of the substrate. In some embodiments, the kit comprises at least a dye composition and a sulfite composition. In some embodiments, the dye composition comprises a compound having a 4-benzohydrylidene-2,5-cyclohexadien-1-imine core functionalized to include at least two substituted or unsubstituted amine groups, the compound having a molecular weight in the range of about 300 g / mol to about 600 g / mol. In some embodiments, the dye composition optionally includes an acid. In some embodiments, the sulfite composition includes a sulfite or a SO2 source.

The application provides a triarylmethane compound and a preparation method and application thereof, and belongs to the technical field of organic compounds. The triarylmethane compound is prepared by connecting a benzopentacyclic ring structure to a key position of a triarylmethane compound skeleton through structure design, and has excellent performance. The preparation method of the triarylmethane compound is simple and convenient, and has a high yield. The blue dye obtained by taking the triarylmethane compound as a blue dye has high selective absorption and transmission capacity at a wavelength of 450 nm, and has high thermal stability.

Provided is a reaction solution for amplifying a nucleic acid, the reaction solution having coloration that is easily visible before a reaction and having no coloration that interferes with fluorescence from the amplified nucleic acid after the reaction. A reaction solution for amplifying a nucleic acid, the reaction solution having a pH of 7.5-10.5 and containing a colorant, the colorant being a water-soluble dye colorless in the reaction solution at a pH of 7.5-10.5 and at 40 DEG C or higher. A reaction solution for amplifying a nucleic acid, the reaction solution containing a color-changing agent and a colorant, the color-changing agent being an oxidizing agent, a reducing agent, or an acidifying agent, and the colorant being a water-soluble dye that changes color or becomes colorless in the reaction solution at 40 DEG C or higher in the presence of the color-changing agent.

The field of the DISCLOSURE lies in active materials in imaging systems. The present disclosure relates to benzofluoran-based active materials and their use in thermo-imaging and full color imaging and methods for their synthesis. The present disclosure also relates to compositions comprising the benzofluoran-based active materials according to the present disclosure. Moreover, the present disclosure relates to a thermo-imaging system comprising a thermochromic layer comprising at least one benzofluoran-based compound according to the present disclosure and to a method for thermo-imaging or full color imaging.

The purpose of the present invention is to provide: a resin composition achieving a high residual film rate when alkaline development is performed; and a compound employed therein.　In order to achieve the aforementioned purpose, the compound of the present invention takes the form represented by formula (1). (In the formula, An- represents an anion that has a specific structure and that has n valency. R1-R4 each independently represent an alkyl group having 5-10 carbon atoms. n represents an integer from 1 to 3.)

The invention provides a blue dye compound and photoresist, and belongs to the technical field of dye compounds. The blue dye compound comprises a compound as shown in a formula I. By designing the molecular structure of the blue dye compound, the dye compound which has relatively good optical performance and relatively high thermal stability, is uniform in dyeing and is simple and convenient in preparation method is obtained.

An object of the present application is to provide a compound which can form a color filter having excellent luminance. The above object is achieved by a compound represented by formula (I). [In formula (I), T 1 represents a divalent aromatic hydrocarbon group which can have a substituent, T 2 represents a divalent aromatic hydrocarbon group which can have a substituent or a divalent aromatic heterocyclic group which can have a substituent, L 1 represents an a-valent aliphatic hydrocarbon group having 1 to 12 carbon atoms which can have a substituent or a group represented by formula (i), and a represents an integer of 2 or more.][In formula (i), T 3 represents an a-valent aromatic hydrocarbon group which can have a substituent or an a-valent aromatic heterocyclic group which can have a substituent, L 2 represents a divalent aliphatic hydrocarbon group having 1 to 5 carbon atoms which can have a substituent.

The present disclosure relates to chromogenic conjugates including a chromogenic moiety and a peroxidase substrate moiety, methods of chromogenic analysis, such as ImmunoHistoChemistry (IHC) and Chromogen In Situ Hybridization (CISH), and methods of making chromogenic conjugates.

Disclosed is an amide-substituted fluoran compound represented by formula (la) wherein R1 to R6 can be the same or different, and are each independently selected from the group consisting of hydrogen, halogen, linear or branched alkyl, cycloalkyl, alkoxy, benzyl, aryl and heteroaryl; R7 to R10 can be the same or different, and are each independently selected from the group consisting of hydrogen, linear or branched alkyl, halogen, carboxyl, alkoxy, aryl or heteroaryl, nitro, amide, and amine; R11 and R12 can be the same or different, and are each independently selected from the group consisting of hydrogen, alkyl, cycloalkyl, alkoxy, cycloalkoxy, carboxyl and benzyl, or are linked via cycloalkyl; and X is either OH or SH. Furthermore a composition, use of a compound or a composition, a thermo-imaging system, a method for thermo-imaging or full color imaging and a method for synthesizing the compound disclosed herein are described.

The subject of this invention is to provide novel compounds that specifically bind to intracellular and / or extracellular vesicles, cellular vesicle staining agents, and methods for fluorescent staining cellular vesicles. The subject matter can be solved by compounds represented by the following formula (1). In formula (1), R1 represents H, C1-C6 alkyl, hydroxyl, amino, or carboxyl groups; R2 represents H, C1-C6 alkyl, hydroxyl, amino, or carboxyl groups. 18 Alkyl, C1-C 18 The alkoxy group, halogen, NO2 or N(CH3)2; R3 and R4 each independently represent H or CH3; wherein, R3 and R4 can also bond with each other to form a ring, in which case R3 and R4 are CH2; l represents 1 or 2, m represents 0 or 1, n represents 1, 2 or 3; Z represents a fluorescent group.

A composition including a N-[4-[[4-(diethyl amino) phenyl](2,5-disulfophenyl)methylene]-2,5-cyclohexadien-1-ylidene]-N-ethylethanaminium sodium salt, where the N-4-4-(diethylamino)phenyl (2,5-disulfophenyl)methylene-2,5-cyclohexadien-1- ylidene-N-ethylethanaminium sodium salt is at least 90% of the weight of such composition. A method of making the composition by a process including sulphonating 2-chlorobenzaldehyde, treatment with sodium sulphite and subsequent basification, a condensation step, an oxidation step and a purification step comprising utilizing HPLC to monitor the sulphonating step, the treatment step, the condensation step, and / or the oxidation step, to determine when one or more reactions of such sulphonating step, treatment step, condensation step, and / or oxidation step are substantially complete and ending such one or more reactions on the basis of the HPLC monitoring. The purification step utilizes flash chromatography to obtain a high purity N-[4-[[4-(diethyl amino) phenyl](2,5-disulfophenyl)methylene]-2,5-cyclohexadien-1-ylidene]-N-ethylethanaminium sodium salt.

The objective of this invention is to provide a compound capable of forming a color filter with excellent brightness. This objective is achieved by a compound represented by formula (I). [In formula (I), T...] 1 and T 2 Independently representing divalent aromatic hydrocarbon groups that may have substituents or divalent aromatic heterocyclic groups that may have substituents, L 1 This refers to an α-valent aliphatic hydrocarbon group with 1 to 12 carbon atoms that may have substituents, or a group represented by formula (i), wherein at least one methylene group contained in the aliphatic hydrocarbon group is substituted with -O-, and α represents an integer of 2 or more. [In formula (i), T] 3 L represents an α-valent aromatic hydrocarbon group that may have substituents or an α-valent aromatic heterocyclic group that may have substituents. 2 This refers to a divalent aliphatic hydrocarbon group having 1 to 5 carbon atoms that may have substituents, wherein at least one of the methylene groups is substituted with -O-.

The present disclosure concerns the design, formulations, preparations and optical properties of compounds of Formulas (I) and (VI):(charged dyem+)x·(counterionn−)y·(counterion receptor)z  (I) and(charged dyem−)x·(counterionn+)y·(counterion receptor)z  (VI).The charged dyem+ is a cationic dye, counterionn− is an anion, and counterion receptor is a binding ligand for the counterionn−, wherein m, n, x and y are integers greater than or equal to 1, and products of x·n and m·y are identical for formula (I).The charged dyem− is a anionic dye, counterionn+ is a cation, and counterion receptor is a binding ligand for the counterionn+, wherein m, n, x and y are integers greater than or equal to 1, and products of x·n and m·y are identical for formula (VI).

The present disclosure provides a novel method of amplifying and sequencing L-form polynucleotide. Further provided include L-form nucleotides and D-form enzymes that can be used in the method. The method of making the L-form nucleotides and D-form enzymes are also provided.

Provided herein are bifunctional compounds that bind p53 and / or promote targeted phosphorylation of p53. The induced phosphorylation of p53 can alter the substrate's structure and function, thus providing compounds which enable phosphorylation of p53, and providing new modes for inducing strategic phosphorylation of p53. Also provided are compounds that are intermediates of the bifunctional compounds. Also provided are pharmaceutical compositions comprising the disclosed compounds, methods of promoting the phosphorylation of p53, and methods of treating a disease or conditions associated with p53 (e.g., cancer) by administering a compound or composition described herein.

The invention belongs to the therapeutic field, in particular the delivery of therapeutic molecules, and more particularly vaccines, but also to the field of medical imaging, and in particular fluorescent markers used in infrared imaging, microscopy, CT scanning, or MRI. The present invention relates to a cationic lipid of formula (I), to a lipid nanoparticle or a liposome containing said lipid, and to a pharmaceutical composition containing same. The invention further relates to the pharmaceutical composition for use as a medicament, preferably in the delivery of negatively charged therapeutic molecules.