178 results about "Ortho position" patented technology

The invention relates to the technical field of catalytic synthesis, in particular to a chloromethylation catalyst, a preparation method of the chloromethylation catalyst and a method for preparing high-purity ortho-position, meta-position and para-position chloromethyl styrene through the chloromethylation catalyst, and the chloromethylation catalyst is prepared by loading sulfonic acid compounds and (or) pyridine compounds and (or) copper salt on a molecular sieve. The method can improve the localization selectivity of chloromethylation. The method for preparing high-purity ortho-position, meta-position and para-position chloromethyl styrene comprises the following steps of: reacting beta-bromophenylethane, paraformaldehyde and lewis acid in the presence of the chloromethylation catalyst to generate chloromethyl beta-bromophenylethane, and then performing elimination reaction under an alkaline condition to generate a chloromethyl styrene crude product; the high-purity ortho-position, meta-position and para-position chloromethyl styrene is obtained after the crude product is rectified, the brand-new catalyst is adopted in the method, the reaction selectivity is enhanced, the process is simple, and industrial production is facilitated.

The invention provides a high-activity adjustable solid catalyst as well as a preparation method and application thereof. The preparation method of the adjustable solid catalyst comprises the following steps: mixing and stirring hexadecyl trimethyl ammonium bromide, ferric chloride hexahydrate and water according to a solid-to-liquid ratio of (1-3): (1-3): (30-40) to prepare a mixed solution; and dipping transition metal salt into the prepared mixed solution, and then carrying out hydrothermal crystallization reaction to prepare the high-activity adjustable solid catalyst. The product prepared by the invention is doped with transition metal, so that the coupling effect is strong; and the structure morphology of the catalyst and the distribution of transition metal elements are more uniform. Metal ions in the regular octahedral structure are located at the vertex, so that reactant adsorption is more facilitated, the selectivity of ortho-alkylation of aromatic compounds is higher, and the activity of catalyzing ortho-alkylation of the catalyst is obviously improved. The metal salt-loaded high-activity adjustable solid catalyst prepared by the invention can be applied to production of hindered phenol antioxidants from phenolic substances.

The invention discloses 4-hydroxy-3-methyl benzoic acid monooxygenase, a strain and a preparation method and application thereof, and relates to the technical field of bioengineering, the nucleotide sequence of the 4-hydroxy-3-methyl benzoic acid monooxygenase is shown as SEQ ID NO: 1, and the amino acid sequence of the 4-hydroxy-3-methyl benzoic acid monooxygenase is shown as SEQ ID NO: 2 and / or SEQ ID NO: 3. The gene of the 4-hydroxy-3-methyl benzoic acid monooxygenase disclosed by the invention can be used for encoding to obtain the 4-hydroxy-3-methyl benzoic acid monooxygenase, and the obtained 4-hydroxy-3-methyl benzoic acid monooxygenase can be used for effectively catalyzing continuous oxidation of ortho-methyl of hydroxyl in 4-hydroxy-3-methyl benzoic acid; the selective continuous oxidation of the ortho-position methyl of the 4-hydroxy-3-methylbenzoic acid can be realized, the 4-hydroxyisophthalic acid is generated, and the compound 4-hydroxyisophthalic acid with industrial added value is synthesized while the selective oxidation of the methyl is solved.

The present disclosure aims to provide a perovskite composition that can obtain a crystalline film that is flat, free of voids, and has high power generation efficiency. [Solution] The perovskite composition according to this embodiment comprises a perovskite compound precursor, a first component which is a solvent for the perovskite compound precursor, and at least one second component selected from the group consisting of nitrogen-containing pyridines and 4-tert-butylpyridine. The nitrogen-containing pyridines are compounds in which a first nitrogen-containing group is bonded to one of the ortho, meta, or para positions of a pyridine ring, and a hydrogen atom is bonded to a position other than the position to which the first nitrogen-containing group is bonded, or at least one of the positions other than the position to which the first nitrogen-containing group is bonded is bonded to one selected from the group consisting of a carbon-containing group, a second nitrogen-containing group, and an alkoxy group.

This invention discloses a migration C(sp²)-H / C(sp³)-H cross-coupling reaction achieved using metal / photoredox catalysis, belonging to the fields of organic chemistry and medicinal chemistry. Under the action of a nickel source, photocatalyst, ligands, base, and additives, this invention enables the reaction of alkanes with ortho-alkenyl-substituted aryl halides or ortho-pyridine-substituted aryl halides in an organic solvent under light irradiation, yielding a series of polysubstituted olefins or polysubstituted aromatic compounds with excellent regioselectivity, stereoselectivity, and good yields, which can serve as active pharmaceutical molecules. This invention uses inexpensive transition metal nickel as a catalyst, readily available alkanes and haloaromatics as raw materials, and features mild and simple conditions, good functional group compatibility, and easy operation.

The invention concerns a composite comprising fibre materials with a density of less than or equal to 450 kg / m3 bonded by an aqueous adhesive composition. The composition comprises a thermosetting resin based on: - at least one aromatic compound A1 comprising at least one aromatic ring bearing at least two functions, one of these functions being an aldehyde function or a hydroxymethyl function and the other being an aldehyde function or a hydroxymethyl function; - at least one aromatic phenol compound A2 bearing at least one aromatic ring bearing at least two hydroxyl functions, said functions being in the meta position relative to one another, the two positions ortho to at least one of the hydroxyl functions being unsubstituted; in which the amount of resin is at least 3.5% by weight of dry extract of resin relative to the total weight of the composition.

The present invention relates to the use as perfuming ingredient of a compound of formula (I) in the form of any one of its stereoisomers or a mixture thereof, and wherein, when R 1 represents a C 1‑2 1-4 alkyl group, X represents a CHO group; or, when R 1 represents a hydrogen atom or a C 1‑2 1-4 alkyl group, X represents a CH(R 6 )CHO group; R 2 , R 3 , R 4 , R 5 and R 6 independently of one another represent a hydrogen atom or a C 1‑2 1-4 alkyl group, or R 3 and R 4 together represent an ethanediyl group; and, relative to position 1, the -C(R 3 )(R 4 )-CH(R 5 )-OH group is an ortho, meta, para substituent of the aromatic ring or a mixture thereof. Furthermore, the compound of formula (I) as part of a perfuming composition or of a perfumed consumer product is also part of the invention.

The application provides a synthesis method of 1-substituted phenanthrene compounds, which comprises the following steps: mixing ortho-substituted aryl diazonium salt with KI, adding a palladium acetate catalyst, adding norbornadiene, adding a base, adding an organic phosphine ligand, adding 2-halobenzoic acid, heating to 80-150 DEG C in an aprotic solvent under a nitrogen atmosphere, and reacting for 2-10 hours to obtain the 1-substituted phenanthrene compounds. The method uses cheap and easily obtained ortho-substituted aryl diazonium salt instead of expensive aryl iodide to prepare 1-substituted phenanthrene compounds, and has the characteristics of easy raw material, mild conditions and simple operation, and is a simple synthesis method of 1-substituted phenanthrene compounds.

The application provides an alpha-diamino nickel complex for catalytically preparing polyethylene, realizes control of polymer molecular weight and branching degree by regulating N-aryl ortho groups in the alpha-diamino nickel complex molecules and polymerization conditions, and has the advantages of high catalytic activity, low cost, stable performance and the like. The prepared polyethylene has high molecular weight, narrow molecular weight distribution, high branching degree and excellent mechanical mechanical performance.

The purpose of the present disclosure is to provide a perovskite composition with which it is possible to obtain a void-free and flat crystal film having high power generation efficiency. A perovskite composition according to an embodiment of the present invention contains: a perovskite compound precursor; a first component that is a solvent of the perovskite compound precursor; and at least one second component selected from the group consisting of pyridines having a nitrogen-containing group and 4-tert-butylpyridine, wherein the pyridines having a nitrogen-containing group are compounds in which a first nitrogen-containing group as a nitrogen-containing group is bonded to any one of an ortho position, a meta position, or a para position of a pyridine ring and hydrogen atoms are bonded to positions of the pyridine ring other than the position at which the first nitrogen-containing group is bonded, or one selected from the group consisting of a carbon-containing group, a second nitrogen-containing group, and an alkoxy group is bonded to at least one position of the pyridine ring other than the position at which the first nitrogen-containing group is bonded.

The invention belongs to the technical field of electrolysis, and discloses a method for preparing p-hydroxyanisole through electrolytic oxidation of anisole. The method comprises the following steps: S1, adding anisole, an acylation reagent, an organic alkali proton trapping agent and an alkaline amine group-containing solvent into a single-chamber electrolytic bath together, starting electrification, carrying out electrolysis, and obtaining a product liquid containing p-methoxytrifluoroacetic acid phenyl ester in the single-chamber electrolytic bath after electrolysis is finished; the organic base proton trapping agent is at least one of N, N-diisopropylethylamine, tributylamine and tripropylamine; and S2, adding a saturated sodium bicarbonate aqueous solution into the product liquid containing p-methoxytrifluoroacetic acid phenyl ester in the step S1 to hydrolyze p-methoxytrifluoroacetic acid phenyl ester, and extracting to obtain p-hydroxyanisole. The selectivity of para-position and ortho-position products of methoxyl on anisole is regulated and controlled, so that the selectivity of p-hydroxyanisole prepared by the method is higher.

Acylated benzene sulfonated compounds with dual functionality can have the following structure:wherein each R is independently hydrogen or a C1 to C11 alkyl, each X is independently an alkali metal ion, an alkaline earth metal ion, and / or a quaternary ammonium cation, n is 1 to 3, and m is 1 to 2, with the proviso that when m is 2, the —OC(O)R groups are not located in an ortho configuration at positions 1 and 2 of the benzene ring. Cleaning compositions including the acylated benzene sulfonated compound are also disclosed.

The invention relates to the technical field of electronic chemicals, in particular to high ortho-ortho '-position four-component phenolic resin and a preparation method and application thereof, the high ortho-ortho'-position four-component phenolic resin has a structure shown in a formula 1, in the formula 1, m, n, o and p are polymerization degrees and are all 0.2-50, the high ortho-ortho '-position four-component phenolic resin is a random copolymer, and no certain connection sequence exists among polymerization monomers; the phenolic resin prepared by the preparation method has high ortho-ortho'position connection degree, so that an I-line photoresist product containing the phenolic resin has obviously improved resolution ratio, the heat resistance is ensured by matching with a cross-linking agent, and the practical application requirements are better met.

A formulation for decreasing aldehyde content in a polymeric material includes a compound which includes at least three moicties of formula (A) wherein each moiety (A) includes an amine moiety (—NH2) bonded ortho or meta to the amide moiety (—CONH); wherein each R1I independently represents a substituent and m is an integer from 0 to 4; and wherein the three moieties (A) are bonded, via their respective amide nitrogen atoms, to respective carbon atoms of a Main Fragment, wherein the Main Fragment includes carbon and hydrogen atoms only and is saturated.

This invention discloses a novel molecular fingerprinting algorithm for assisting in the design of MOFs for acid gas separation, comprising the following steps: S1, using drawing software to draw 17 possible ortho, meta, and para positions of benzene rings, five-membered rings, and six-membered rings, obtaining their .mol ​​files; S2, converting the .mol ​​files to .smart format and writing a separate .py file for the new fingerprint; S3, calling the original fingerprint in the newly written .py file, adding the two results to obtain a new 184-bit fingerprint; S4, using the new fingerprint to test multiple CoRE-MOFs using various machine learning methods. This invention can determine whether the N-bond in a five-membered or six-membered ring of a macromolecule is ortho, meta, or para, which is beneficial for identifying differences in molecular structure between molecules with different performance characteristics, thereby accelerating the screening of high-performance materials, effectively saving time and costs, and shortening the development cycle.

The application discloses a kind of big steric hindrance C-C coupling palladium ligand and synthesis method, ligand is used naphthyl as the main group of stable ligand, this group provides big plane rigid configuration during ligand use, simultaneously, it provides big π electron for complex molecule to stabilize complex;In addition, the configuration of pyridofuran is used, the N coordination point of traditional N-P bidentate ligand is introduced O by furan this functional group in ortho position to adjust the chemical environment of intramolecular N coordination point, so as to modify the traditional N-P bidentate ligand to tridentate ligand, this change can effectively increase the penetration ability of Pd active center in actual ligand use to improve catalytic activity.

The invention discloses a copper-catalyzed aryl aldehyde ortho-position direct C-H etherification method, which comprises the following steps: by taking aryl aldehyde as a raw material, adding alcohol or phenol as shown in a formula (II), a copper catalyst, a guiding group, alkali and a solvent into a reactor, and reacting in an argon gas atmosphere to prepare an aryl ether compound as shown in a formula (III), a substituent group R1 is hydrogen, methyl, trifluoromethyl, methoxyl, phenyl, iodo, isopropyl, trimethylsilyl, dimethylamino, fluoro, chlorine, ester, tourmaline, naphthyl, isoquinolyl, benzothienyl or phenanthryl; a substituent group R2 is hydrogen, methyl, trifluoromethyl, methoxyl, phenyl, iodo, isopropyl, trimethylsilyl, dimethylamino, fluoro, chlorine, ester, tourmaline, naphthyl, isoquinolyl, benzothienyl or phenanthryl; and a substituent group R2 is methyl, 4-fluorophenyl, cyclobutane methyl, 4-tert-butyl phenyl, pentafluorophenyl, 4-cyanophenyl, 4-methyl ester phenyl, 3-nitrophenyl, adamantane methyl, cyclohexyl or an oestrone analogue. The copper catalyst and amino acid which are low in cost and easy to obtain are used as guiding groups, the operation process is simple and efficient, and the corresponding aryl ether compound can be obtained with the good yield.

The invention relates to the technical field of medicine synthesis, and particularly discloses a preparation method of a cefdil intermediate. According to the invention, trichloroisocyanuric acid (TCCA) is taken as a green chlorination reagent, and reaction solvent and temperature are selected, so that the problem that benzene ring polychlorination side reaction and aldehyde functional group nucleophilic substitution side reaction are effectively inhibited while ortho-position high-selectivity mono-chlorination of phenolic hydroxyl is realized is successfully solved; and thus, the 2-chloro-3-hydroxy-4-methoxybenzaldehyde can be obtained at a high yield. On the basis, according to the scheme, subsequent anhydridation and amidation steps are further optimized, trimethylacetyl chloride is adopted to replace a traditional highly toxic activating reagent, safety and atom economy are improved, and meanwhile continuity and high efficiency of the reaction are ensured. The whole process route is reasonable in design, simple and convenient to operate and high in safety, raw materials and reagents are easy to obtain, the total yield of the reaction and the purity of the product are remarkably improved, and the method shows a wide application prospect in large-scale industrial production of the ceftidil.

A system for effecting conversion of hydrogen from an ortho-isomer to a para-isomer is disclosed. The system comprises at least one reactor (10) comprising at least one reaction chamber (11) filled with a catalytic bed comprising a metal organic framework (MOF), characterized in that the at least one reaction chamber (11) is surrounded by a housing (12) through which a flow of cooling fluid is susceptible to pass.

The invention provides a method for synthesizing an aryl phosphine ligand by catalyzing fluoroaromatic hydrocarbon with iron, and provides a simple, convenient and green method for synthesizing an organic phosphine ligand. Specifically, in the presence of a Fe catalyst, a coupling reaction reagent and alkali, a fluorine aromatic hydrocarbon type compound B and a diphenyl phosphine oxide type compound D are subjected to a coupling reaction in an organic solvent to prepare an aryl phosphine ligand compound C, and A is a carbon atom or a nitrogen atom; when A is a carbon atom, R is a 5-6 substitutable or non-substitutable heterocyclic ring, phenyl, C1-C4 alkyl or CF3; when R is phenyl, R is ortho-substituent; when A is a nitrogen atom, R is hydrogen, and R is not connected with A.

A polypropylene composition (PC) comprising: a. from 95.0 to 99.99 wt.-%, of a polypropylene (PP), preferably a propylene homopolymer (HPP); and b. from 0.01 to 5.0 wt.-%, of a compound according to Formula (I), wherein each R is independently selected from C1 to C6 alkylene, C2 to C6 alkenylene and a single bond, each R′ is independently selected from H and C1 to C6 alkyl, each R″ is independently selected from H and C1 to C22 alkyl, wherein each alkylene, alkenylene and alkyl group may optionally be substituted by deuterium or fluorine, and the two substituents on the central benzene ring may be either positioned in an ortho, meta or para relationship; wherein the polypropylene composition (PC) has an MFR2 of from 400 to 5000 g / 10 min and a melting temperature Tm of from 140 to 170° C.

The application relates to a novel triarylamine compound with two carbazole units introduced on a biphenyl-triarylamine and application thereof, wherein, by fixing one of the carbazole units at the ortho position of the biphenyl in the triarylamine, a twisted structure is formed, thus effectively inhibiting the aggregation of the molecule, so that a stable dense film is formed; by changing the position of the other carbazole and the structure of the other two aryl groups of the triarylamine, the energy level barrier and the hole mobility can be effectively regulated, and the efficiency and the service life of the device are improved. Meanwhile, the double-carbazole system can more effectively inhibit the diffusion of electrons from the light-emitting layer to the hole side, so that the service life of the device is further improved.

The present invention relates to an aqueous adhesive composition comprising a thermosetting resin based on: - at least one aromatic hydrocarbon compound A1 comprising at least one aromatic hydrocarbon compound comprising at least two aromatic rings bearing a single hydroxyl function, it being understood that at least one of the ortho or para positions of each aromatic ring is unsubstituted; - at least one aromatic compound A2 comprising a single phenol which is unsubstituted or substituted by a single alkyl or a single alkenyl group; and - a formaldehyde compound A3. According to the invention, the aromatic compound A2 is present in a weight content of the dry extract of the adhesive composition of less than or equal to 0.18.

The invention relates to the field of chemical engineering, in particular to a bio-based hindered phenol antioxidant and a preparation method thereof. According to the bio-based hindered phenol antioxidant provided by the invention, a tert-butyl group with relatively large steric hindrance is arranged at the ortho-position of a hydroxyl group, a linear alkyl group (C15H31-) is arranged on a benzene ring, and the tert-butyl group and the linear alkyl group jointly regulate and control the activity of a phenolic hydroxyl group, so that the bio-based hindered phenol antioxidant has very good solubility in a non-polar medium (such as polyolefin plastics as polyethylene PE, polypropylene PP and the like); the compatibility is improved, volatilization and migration precipitation are reduced, and the thermal stability and the antioxidant activity are greatly improved. Moreover, the adopted raw material cardanol is a bio-based material and is safe and environment-friendly, and the preparation method is simple and easy to implement, mild in condition and beneficial to large-scale production.

The present invention relates to an extrusion molding catalyst for an ortho-alkylation reaction and a preparation method thereof, and more particularly, to an extrusion molding catalyst for an ortho-alkylation reaction, which can minimize the mass diffusion resistance of the catalyst in an ortho-alkylation reaction of a phenolic compound, and improve the yield of the catalyst. Therefore, the ortho-alkylation reaction product with high selectivity and conversion rate is obtained, and the invention also relates to a method for preparing the ortho-alkylation reaction product by using the catalyst.

Crosslinked aromatic compounds having the structure (I) are described. Compositions comprising these cross-linked compounds are also described. For example, a composition also includes a photoacid generator. Furthermore, methods of coating a substrate using such a composition and generating an image by exposing it to radiation, which can be used as a mask in microelectronic manufacturing, are described. Also disclosed is a process for the selective iodination of a polyphenol compound at the ortho-position of the phenolic function using a 1-iodopyrrolidine-2, 5-dione moiety to produce a phenolic precursor of a cross-linked aromatic compound by selective iodination in the presence of an aryl sulfonic acid. (I)

The invention relates to an adhesive composition comprising at least: - a compound comprising at least two epoxy functions; - a phenol comprising one or more aromatic rings, provided that: in the case of a single aromatic ring, the latter bears at least three hydroxyl functions; or in the case of several aromatic rings, at least two of them bear at least three hydroxyl functions each, provided that at least one ortho position of the at least one of the hydroxyl functions is unsubstituted; - a compound comprising at least one double bond that can have a linear, branched and / or cross-linked macrostructure which can be organised into a structure of the "core shell rubber", micelle or particle type; and which comprises less than 0.1 wt.-% catalyst, with the catalyst not comprising an antimony-based catalyst.

The invention discloses three kinds of ortho-substituted diaryl benzene weak acting group organic light-emitting materials with narrow-band emission. The three kinds of ortho-substituted diaryl benzene weak acting group organic light-emitting materials are a compound 19-Naph-Phen-Ben, a compound 99-Phen-Ben and a compound 91-Phen-Pyre-Ben. According to the preparation method disclosed by the invention, 9-(2-bromophenyl) phenanthrene is used as a raw material, and the 9-(2-bromophenyl) phenanthrene and arylboronic acid are subjected to suzuki coupling reaction to obtain corresponding ortho-substituted diaryl benzene. According to the ortho-substituted diaryl benzene weak acting group organic light-emitting material, space conjugation can be regulated and controlled by changing the size of an aryl element, so that a vibration energy level emission peak is inhibited, ultra-narrow band emission with the half-peak width smaller than 10 nm is finally achieved, and the ortho-substituted diaryl benzene weak acting group organic light-emitting material has the potential of being applied to photoelectric devices.

A method of decreasing aldehyde content in a polyoxymethylene (POM) polymer, increasing Oxidative Induction Time (OIT) and / or increasing thermal stability comprises contacting the POM polymer with an aldehyde scavenger selected from: (i) a compound XX which includes at least three moieties of formula (AA) wherein each moiety (AA) includes an amine moiety (—NH2) bonded ortho or meta to the amide moiety (—CONH), each R1 independently represents a substituent and m is an integer from 0 to 4; and the three moieties (AA) are bonded, via their respective amide nitrogen atoms, to respective carbon atoms of a Main Fragment, wherein the Main Fragment includes carbon and hydrogen atoms only and is saturated; and (ii) a cyanoacetamide.

The present application belongs to a curing agent structure. An epoxy resin curing agent, an insulating epoxy resin, and a preparation method thereof are provided, including at least two benzene ring structures or at least two non-coplanar rigid alicyclic structures. Two adjacent benzene ring structures or non-coplanar rigid alicyclic structures are connected by methylene, and an amino functional group is arranged on each side of the integral structure. An ortho position of the amino functional group is provided with an electron-withdrawing substituent group or several sterically hindered substituent groups. By introducing benzene rings, the thermal stability of the obtained epoxy resin is enhanced. By introducing a high electron-withdrawing group and a large sterically hindered group or using a non-coplanar alicyclic structure with saturated electrons instead of a benzene ring, it can maintain good electrical properties in an environment with a high temperature gradient and a large electric field.