5 results about "Vicinal" patented technology

The present application relates to a kind of preparation method of vicinal diol compound, which comprises the following steps: in non-aqueous solvent, formula (I) compound and reducing agent are reacted under light condition, to obtain the vicinal diol compound shown in formula (II);The reducing agent is formic acid or formate;The wavelength of the light is less than 390nm;Its reaction formula is as follows.The preparation method of the present application does not need transition metal catalyst, also does not need other special catalyst and special additive, and the aldehyde ketone substrate can be reacted with formic acid or formate in solvent by specific wavelength of light, to obtain corresponding vicinal diol compound with high yield, its reaction condition is mild, has wide substrate applicability, and green and environmental protection, simple and practical operation method, provides an effective synthesis strategy for the synthesis of shikimic alcohol compound.

The application belongs to the technical field of compound preparation, and discloses a preparation method of (1'S, 2'S)-eugenol glycerol 3'-O-beta-D-glucopyranoside. The method is characterized in that: a phenolic hydroxyl group allyl compound protected by a benzyl group is subjected to O-glycosylation reaction with a D-glucopyranosyl donor protected by an acetyl group, so as to obtain an olefin type protected glycoside intermediate which retains a side chain carbon-carbon double bond; then, asymmetric dihydroxylation reaction is performed on the intermediate, so as to construct a target vicinal diol chiral structure; finally, the acetyl protecting group of the sugar hydroxyl group and the benzyl protecting group of the phenolic hydroxyl group are sequentially removed, so as to obtain the target compound. The preparation method of (1'S, 2'S)-eugenol glycerol 3'-O-beta-D-glucopyranoside is characterized in that: the glycoside bond is constructed before dihydroxylation, which is beneficial to reducing the competition reaction of multiple hydroxyl groups and realizing the preparation of the target compound.

In some aspects, the present disclosure provides polyiodinated polyamino compounds that comprise a residue of a carboxylic-acid-substituted polyamino compound that is linked to a residue of a polyiodinated aromatic compound that comprises a plurality of vicinal diol groups, each having a proximal hydroxyl group and a distal hydroxyl group, wherein the polyiodinated polyamino compound is formed by a process that comprises reacting a single carboxylic acid group of the carboxylic-acid-substituted polyamino compound in an ester coupling reaction with a single hydroxyl group selected from the proximal and distal hydroxyl groups of the plurality of vicinal diol groups of the polyiodinated aromatic compound, thereby forming an ester group that links the residue of the carboxylic-acid-substituted polyamino compound to the residue of the polyiodinated aromatic compound. Other aspects of the present disclosure pertain to methods of making such polyiodinated polyamino compounds and systems employing such polyiodinated polyamino compounds.

A first aspect of the invention relates to a purification process for obtaining vicinal toluenediamine. In a second aspect, the invention is directed to vicinal TDA (vTDA) obtained or obtainable from a process of the first aspect of the invention, comprising less than 100 weight-ppm of a toluidine compound of formula (I). A third aspect of the invention is related to vicinal TDA (vTDA) having a purity in the range of at least 99 weight- % and comprising less than 100 weight-ppm of a toluidine compound of formula (I).

Carbon dioxide foam treatment fluid comprising: a plurality of functionalized silanol-group silica nanoparticles the silanol group selected from the group consisting of an isolated silanol group, a vicinal silanol group, a geminaol silanol group, and any combination thereof; wherein the plurality of functionalized silanol group silica nanoparticles comprise crystalline silica; and a surfactant having a hydrophilic-lipophilic balance (HLB) value of 8 to 18.