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Composite preservative containing amino acid derivatives and preparation method for composite preservative and cosmetic

A technology for compounding preservatives and derivatives, applied in the field of preservatives, can solve problems such as skin irritation and unsatisfactory antiseptic effects, and achieve safe use, good antiseptic and antibacterial effects

Pending Publication Date: 2020-05-12
广东迪美生物技术有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the existing preservatives can have a certain antiseptic effect, they have a certain stimulating effect on the skin, and the antiseptic effect is not ideal.

Method used

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  • Composite preservative containing amino acid derivatives and preparation method for composite preservative and cosmetic
  • Composite preservative containing amino acid derivatives and preparation method for composite preservative and cosmetic
  • Composite preservative containing amino acid derivatives and preparation method for composite preservative and cosmetic

Examples

Experimental program
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Effect test

Embodiment 1

[0040] The compound preservative containing glycine derivatives in the present embodiment is prepared by the following method:

[0041] Step A, take the following components by weight percentage:

[0042] Bis-octylaminoethylglycine: 10%

[0043] Capryl Glycine: 3%

[0044] Sodium hydroxide: 0.55%

[0045] Hexylene glycol: 30%

[0046] Water: 56.45%;

[0047] Step B, stirring and mixing bis-octylaminoethylglycine, caprylylglycine, hexanediol and water at 50-70°C;

[0048] Step C, adding sodium hydroxide for neutralization, so that the raw materials are completely dissolved into a transparent liquid.

Embodiment 2

[0050] The compound preservative containing glycine derivatives in the present embodiment is prepared by the following method:

[0051] Step A, take the following components by weight percentage:

[0052] Bis-octylaminoethylglycine: 5%

[0053] Lauroyl Lysine: 5%

[0054] Potassium hydroxide: 0.75%

[0055] Pentylene Glycol: 30%

[0056] Butanediol: 10%

[0057] Water: 49.25%;

[0058] Step B, stirring and mixing bis-octylaminoethylglycine, lauroyl lysine, potassium hydroxide, pentylene glycol, butanediol, and water at 50-70°C;

[0059] Step C, adding potassium hydroxide for neutralization, so that the raw materials are completely dissolved into a transparent liquid.

Embodiment 3

[0061] The compound preservative containing glycine derivatives in the present embodiment is prepared by the following method:

[0062] Step A, take the following components by weight percentage:

[0063] Bis-octylaminoethylglycine: 10%

[0064] Lauryl iminodipropionic acid: 2%

[0065] Sodium hydroxide: 0.4%

[0066] Hexylene glycol: 30%

[0067] Water: 57.6%;

[0068] Step B, stirring and mixing bis-octylaminoethylglycine, lauryl iminodipropionic acid, hexanediol and water at 50-70°C;

[0069] Step C, adding sodium hydroxide for neutralization, so that the raw materials are completely dissolved into a transparent liquid.

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Abstract

The invention discloses a composite preservative containing amino acid derivatives. The composite preservative contains the amino acid derivatives, 1,2-vicinal diol and a solvent; the amino acid derivatives are octanoyl amino acid derivatives and / or lauroyl amino acid derivatives. The composite preservative can disturb and inhibit a physiological environment of a cell membrane, namely that the composite preservative is selectively gathered on an oil-water interface in an oil-in-water emulsion system, so that a food source for microorganisms in a region where the composite preservative is gathered is changed to result in being not in favor of growth of the microorganisms, and thereby, the growth of the microorganisms is inhibited; while after the 1,2-vicinal diol is compounded with the octanoyl amino acid derivatives and lauroyl amino acid derivatives dissolved in the solvent, a synergistic effect is generated, so that antisepsis and bacteriostasis effects of octyl chains in the octanoyl amino acid derivatives and lauryl chains in the lauroyl amino acid derivatives can be enhanced to make the composite preservative have a good antisepsis and bacteriostasis effect, and the compositepreservative is very safe and mild to use. The invention further provides a preparation method for the composite preservative and a cosmetic containing the composite preservative.

Description

technical field [0001] The invention relates to the technical field of preservatives, in particular to a compound preservative containing amino acid derivatives, a preparation method thereof, and cosmetics containing the compound preservative. Background technique [0002] Preservatives are one of the indispensable components of cosmetics, which ensure that cosmetics will not deteriorate due to microbial contamination during production, storage and use. In recent years, more and more consumers use cosmetics to enhance their image and beautify themselves. Although the existing preservatives can have a certain antiseptic effect, they have a certain stimulating effect on the skin, and the antiseptic effect is not ideal. Therefore, it is of great practical significance to develop a mild, safe and efficient anti-corrosion system. [0003] The prior art discloses a multifunctional facial cleanser and a preparation method thereof, and records that the multifunctional facial clean...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/44A61K8/34A61Q19/00
CPCA61K8/44A61K8/345A61Q19/00A61K2800/524A61K2800/5922A61K2800/10
Inventor 宋天龙刘永龙杨娟陶宏兵黄泽彬邓小锋黄小茉
Owner 广东迪美生物技术有限公司
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