The invention discloses an urazole chiral axis compound. The urazole chiral axis compound is represented by a formula I or II, wherein the R<1a> is selected from
alkyl,
halogen, phenyl, substituted phenyl and other groups shown in the descriptions, the R<5> is selected from
halogen,
alkyl and alkoxy, the R<6> and the R<7> are respectively and independently selected from an aliphatic
substituent group and an aromatic
substituent group, and the R<1b>, R<1c>, R<1d> and R<1e> are respectively and independently selected from
hydrogen,
halogen, phenyl, substituted phenyl,
alkyl, alkoxy, hydroxyl, a ester group, an
aldehyde group, a cyano group and
amide. The R represents an
aryl group free of a
substituent group or provided with one or more of substituent groups, and the R' represents
hydrogen or alkyl. The invention further discloses an asymmetric synthesis method of the compound. The high-yield high-ee-value urazole chiral axis compound is prepared through synthesis under the moderate
reaction conditions. The synthesis method has very good substrate adaptability and can achieve synthesis of more than shown grams of the compound under the situation that the dosage of a catalyst is decreased. The compound can serve as a catalyst or a ligand for a certain asymmetric reactions.