120 results about "Biphenyl derivatives" patented technology

A biphenyl derivative is included in a photosensitive layer of an electrophotographic photoconductor. The electrophotographic photoconductor includes a single-layer photosensitive layer coated on a conductive substrate. The photosensitive layer includes a resin binder, a charge generation substance, a hole transport substance, and an electron transport substance. An electrophotographic apparatus using such an electrophotographic photoconductor has excellent electrical characteristics in a positive chargine system and is stable in repeated use.

This invention provides biphenyl derivatives of formula I: wherein R<1>, R<2>, R<3>, R<4>, R<5>, R<6>, R<7>, W, a, b and c are as defined in the specification, or a pharmaceutically acceptable salt or solvate or stereoisomer thereof. The biphenyl derivatives of this invention possess both beta2 adrenergic receptor agonist and muscarinic receptor antagonist activity and therefore, such biphenyl derivatives are useful for treating pulmonary disorders, such as chronic obstructive pulmonary disease and asthma.

Biphenyl derivatives useful as ion channel antagonists are disclosed herein. The compositions thereof are useful for treating or relieving pain-related conditions.

A pesticide having stabilized high pesticidal effects for crop plants infected with plant diseases, is presented. The pesticide contains a biphenyl derivative represented by the formula (I) or its salt, as an active ingredient: wherein X, Y and Z are each independently a halogen atom, a hydroxyl group, a formyl group, an alkyl group which may be substituted, an alkoxy group which may be substituted, an alkylthio group, an alkylsulfonyl group, an alkylsulfinyl group, or the like, A is a carbonyl group, a thiocarbonyl group, an alkylene group, or a single bond, R¹ and R² are each independently a hydrogen atom, an alkyl group which may be substituted, an alkenyl group which may be substituted, an alkynyl group which may be substituted, an aryl group which may be substituted, a formyl group, an alkylcarbonyl group, a cyano group, or the like, and m and n are each independently 0, 1, 2, 3 or 4.

The present invention provides a chiral phase-transfer catalyst of the following formula (I):

The compound (I) can be produced by reacting a 2,2′-dimethylene bromide-1,1′-biphenyl derivative, which can be produced through comparatively small number of steps, with an easily available secondary amine.

The invention relates to a method for electrochemical synthesis of a carbazole compound. The method comprises the following steps: taking an N-substituted acylamino biphenyl derivative as a substrate,adding the substrate and an electrolyte into an organic solvent, inserting an electrode, stirring, carrying out electrolytic reaction, stirring in nitrogen at room temperature by taking a carbon rodas an anode and a platinum sheet electrode as a cathode, carrying out constant-current reaction, removing the solvent by using a rotary evaporator after the reaction is finished, and carrying out rapid silica gel column chromatography purification on residues to obtain a product. According to the method, the reaction is electrically promoted, expensive metal catalysts and other oxidizing agents are not needed, the reaction can be carried out mildly at the room temperature, the selectivity is good, the yield is high, the whole process is simple and easy to implement, and the concept of green chemistry is met. According to the method, no extra oxidant is needed, the method is simple and efficient, the substrate is wide in applicability, and the yield of compounds with different substituent effect groups can be very high. The preparation method is simple, economical and environment-friendly, and has a certain industrial prospect.

A non-aqueous electrolytic solution favorably employable for a lithium secondary battery employs a non-aqueous electrolytic solution which comprises a non-aqueous solvent and an electrolyte which further contains 0.001 to 0.8 weight % of a biphenyl derivative having the formula:

in which each of Y¹ and Y² represents hydroxyl, alkoxy, hydrocarbyl, hydrogen, acyloxy, alkoxycarbonyloxy, alkylsulfonyloxy, or halogen, and each of p and q is an integer of 1 to 3.

A method for producing biphenyl and its derivative comprising oxidatively coupling a benzene aromatic compound in the presence of a catalyst comprising a palladium salt, a copper salt, and a bidentate ligand compound capable of forming a complex with the palladium salt via the nitrogen atom and the oxygen atom in the molecule thereof in an atmosphere containing molecular oxygen. In particular, an improved method for selectively producing an asymmetrically substituted biphenyl derivative, such as a 2,3,3′,4′-biphenyltetracarboxylic acid tetraester, which comprises oxidatively coupling a substituted aromatic compound, such as a phthalic diester, in the presence of the catalyst in an atmosphere containing molecular oxygen without replenishing with a ligand.

Biphenyl derivatives are disclosed for use in the treatment of androgen-dependent diseases such as prostate cancer, benign prostatic hyperplasia, precicious puberty, polycystic ovarian syndrome, acne, hirsutism, seborrhea, androgenic alopecia and premature male baldness. For example, some preferred compounds having the structure: are formulated together with pharmaceutically acceptable diluent or carrier for topical use in the treatment of androgen-dependent prostate cancer.

Biphenyl derivatives having four substituents at meta positions of biphenyl structure, which is a core molecular structure, and organic electroluminescent devices using the biphenyl derivatives. The biphenyl derivatives are phosphorescent host compounds having amorphous structures and have excellent thermal stability and high solubility in general organic solvents, is easily to use for solution (or wet) process, and can easily energy-transfer to a metal complex used as dopant. The biphenyl derivatives also can be used as blue host materials of phosphorescent emission layer, hole transporting materials, or a hole injecting materials of an organic electroluminescent device.

The invention discloses a preparation method of biphenyl derivatives. According to the method, the biphenyl derivatives are generated by carrying out coupling reaction by taking non-water-soluble alkyl-substituted tetrahydrofuran as a solvent, halogenated O-xylene, halogenated alkyl phthalate and halogenated phthalimide as raw materials, manganese, aluminum or zinc as a reducing agent and nickel salt, cobalt salt, palladium salt, iron salt, copper salt or a complex compound composed of the salts, organic phosphorus and organic amine as a catalyst.

The invention discloses a method for preparing a 2-amino biphenyl derivative. The method concretely comprises the following steps: dissolving a polyaniline derivative, a phenylhydrazine derivative and a phthalocyanine metal complex catalyst into a solvent, and reacting at 20-80 DEG C, so as to obtain the 2-amino biphenyl derivative. The polyaniline derivative is used as an initiator, and the prepared 2-amino biphenyl derivative is available in raw material and diverse in variety. The product obtained by using the method disclosed by the invention is diverse in variety, can be directly used, and also can be used for further reaction with the others. Meanwhile, the method is mild in reaction conditions and simple in reaction operation and post-treatment process, the reaction process is catalyzed, the dosage of a reagent and generation and emission of a reaction waste are greatly reduced, and the method is high in productive rate and applicable to large-scale production.

The invention discloses a low-cost and environment-friendly synthesis method of biphenyl derivatives. According to the method, a water-insoluble environment-friendly solvent cycloalkyl methyl ether is used as a solvent system of the reaction, halogenated o-xylene, halogenated alkyl phthalate ester or halogenated phthalimide is used as raw material and is subjected to coupling reaction in the presence of manganese or aluminum, or zinc as a reducing agent and a nickel salt, cobalt salt, palladium salt, iron salt or copper salt of transition metal or a complex prepared from the salt and a ligand such as organic phosphorus phosphine and organic amine as a catalyst to obtain the biphenyl derivatives.

The invention discloses novel compounds for fluorescent identification of metal ions, relates to naphthalene biphenyl derivatives used as a fluorescent probe of metal ions and application thereof and belongs to the field of biochemistry. The structural general formula of the naphthalene biphenyl derivatives is shown in the specification, and in the general formula, R1, R2 and R3 represent aromatic groups, namely phenyl, pyridyl, quinolyl, naphthyridinyl, pyrrolyl, anilino and other groups and R1, R2 and R3 are not phenyl at the same. The fluorescent probe can sensitively identify various metal ions such as copper ions, iron ions and other metal ions. Certain probe molecules have identification action to two types of metals. The fluorescent probe has good selectivity and high sensitivity, and has better application prospect in identification and detection of the metal ions in biological samples or the environment.

Disclosed are: a lithium secondary battery which comprises a positive electrode containing, as a positive electrode active material, a lithium-containing metal oxide that contains at least one metal element selected from nickel, manganese and iron, a negative electrode containing, as a negative electrode active material, a carbon material capable of absorbing and releasing lithium, and a non-aqueous electrolytic solution comprising a non-aqueous solvent and an electrolyte salt dissolved in the non-aqueous solvent, wherein the lithium secondary battery is characterized in that the non-aqueous electrolytic solution contains 0.1 to 5 mass % of 1,2,3,4-tetrahydronaphthalene and 0.1 to 5 mass % of a biphenyl derivative and/or an alkyl phenol derivative; and a non-aqueous electrolytic solution for use in the lithium secondary battery. The lithium secondary battery can have an excellent post-low-temperature-cycle recovery rate even after the battery is exposed to a high-temperature environment.

The present invention relates to a preparation method of 3,5-diflurodiphenyl derivative. Said preparation method includes reaction of difluorohalogeno-benzene and phenyl boric acid under the action of catalyst. Said invention also provides its chemical structural formula.

The invention discloses an organic light-emitting material with a distorted molecular structure, and application thereof to an organic electroluminescence device, and belongs to the technical field oforganic electroluminescence. The general molecular formula of the organic light-emitting material is shown as follows: two phenanthro[9,10-d]-imidazole groups are connected to 2 and 2' positions of biphenyl. In the category of molecule, the whole molecule presents a high distortion structure, and the special modular structure causes the organic light-emitting material to have a high triple excited state energy level. The di-phenanthro[9,10-d]-imidazole-biphenyl derivative can be used as a main material for preparing a light emitting layer doped with the electroluminescence device which emitsdark blue light. The above device can be used for preparing organic electroluminescence devices or organic electroluminescence illumination light sources. (The formula is shown in the description.).