113 results about "Phenylhydrazine" patented technology

The invention discloses 1, 2-dibromo-6-tert-butyl-9-(4-tert-butylphenyl)-9H-carbazole and a synthesis method of the 1, 2-dibromo-6-tert-butyl-9-(4-tert-butylphenyl) The method comprises the following steps: taking 3-nitrophthalic acid as an initial raw material, reacting trichloroisocyanuric acid with liquid bromine to obtain 1, 2-dibromo-3-nitrobenzene, reducing by stannous chloride to obtain 2, 3-dibromoaniline, carrying out diazotization reaction to obtain 2, 3-dibromophenylhydrazine, reacting with p-tert-butyl cyclohexanone, and reacting by using 2, 3-dichloro-5, 6-dibromophenylhydrazine to obtain 2, 3-dibromophenylhydrazine. The preparation method comprises the following steps: carrying out dehydrogenation on 2, 6-dicyanobenzoquinone to obtain 1, 2-dibromo-6-tert-butyl-9H-carbazole, and finally reacting the 1, 2-dibromo-6-tert-butyl-9H-carbazole with 4-tert-butyl iodobenzene to obtain the 1, 2-dibromo-6-tert-butyl-9-(4-tert-butylphenyl)-9H-carbazole. Due to the existence of a bromine atom functional group on the 1, 2-dibromo-6-tert-butyl-9-(4-tert-butylphenyl)-9H-carbazole, the further conversion of the compound has expandability, and the compound can be used as a material / drug molecule precursor in the fields of organic light-emitting semiconductors, pharmaceutical chemistry and the like.

The invention discloses a synthetic method of a fluorescent dye, which comprises the following steps: A, dropwise adding POCl3 into DMF (Dimethyl Formamide) at the temperature of 0 DEG C under the condition of protective atmosphere and stirring, and fully reacting; continuously dropwise adding cyclohexanone, heating, stirring, fully reacting, adding the reaction liquid into ice water, and separating out a solid first compound; b, under the protective atmosphere, stirring and refluxing p-sulfonyl phenylhydrazine, 3-methyl-2-butanone and acetate in acetic acid to react completely, cooling the reaction liquid to-10 to 5 DEG C, stirring, and separating to obtain a second compound; c, under the protective atmosphere, after the second compound and 1, 4-butanesultone are stirred, refluxed and completely reacted in xylene, separating to obtain a third compound; and D, stirring and refluxing the third compound, the first compound and acetate in methanol at the temperature of 80 DEG C under the conditions of protective atmosphere and light shielding, simultaneously dropwise adding acetic anhydride, cooling to room temperature after full reaction, and separating and purifying. According to the scheme, the synthesis process is simple and efficient, and high-quality synthesis of the target dye S0456 is effectively realized.

The invention relates to the field of chemical pharmacy, and in particular to a synthesis process of apixaban, comprising the following steps: using 3-chloro-1-(4-(2-oxopiperidin-1-yl)phenyl-5,6-dihydropyridine-2(1H)-one (intermediate A) to react with oxalyl chloride monoester to obtain compound B, then reacting with p-methoxyphenylhydrazine hydrochloride to form a ring through condensation and coupling to obtain compound D, and finally preparing apixaban through amine ester exchange of compound D. Compared with the prior art, the invention has the advantages of: 1. The synthesis process is more efficient and mild, the operation is simple, and the raw materials are easy to obtain; 2. It avoids the use of expensive or toxic and irritating reagents; 3. The total yield is high and is suitable for industrial production.

The present invention relates to the field of medicine, and discloses a preparation method for reducing the content of oxytetracycline impurity C, comprising the following steps: S1: oxytetracycline crude product is added to a saturated alcohol aqueous solution, then substituted phenylhydrazine is added, and the reaction is stirred for 0.5-1.2h; S2, step S1 reaction solution is filtered, the filter cake is beating with a saturated alcohol aqueous solution for 1h, filtered, and the filter cake is washed with a saturated alcohol aqueous solution once; S3, step S2 solid is added to a saturated alcohol solution, hydrochloric acid solution is added to adjust the system pH to 2-3, stirring reaction, amine solution is added to adjust the pH to 5-6, and solvent is filtered out; S4, step S3 solid is placed in a vacuum drying oven and dried to constant weight to obtain a oxytetracycline finished product with low impurity C content, and the impurity C content in the finished product is as low as 0.2%. The preparation method for reducing the content of oxytetracycline impurity C provided by the present invention can effectively remove the difficult-to-remove impurity C in oxytetracycline compared to traditional purification methods, and its content can be reduced from 2-5% to less than 0.3%, greatly improving product quality and reducing adverse drug reactions.

The invention discloses a method for synthesizing a 1-aminoindole derivative through electrooxidation cyclization, which comprises the following steps: adding an acetyl phenylhydrazine derivative, an alkyne derivative, [Cp * RhCl2] 2, sodium acetate, potassium hexafluorophosphate, t-BuOH and distilled water into a container filled with magnetons to obtain a mixed reaction solution; placing the mixed reaction liquid in a sand bath preheated to a preset temperature, taking a carbon rod as an anode and a platinum sheet as a cathode, inserting one ends of the cathode and the anode into the mixed reaction liquid at intervals, and connecting the other ends of the cathode and the anode to an electrochemical workstation to construct an electrooxidation cyclization system; and electrifying the electrochemical workstation to react for a preset time, so as to prepare the 1-aminoindole derivative. The method provided by the invention takes flowing electrons as an oxidant to replace an external oxidant, realizes regeneration internal circulation of the catalyst through driving of an electrochemical workstation, does not need the external oxidant, and is mild in reaction condition, simple in synthesis step and relatively short in reaction time.

The present invention proposes a method and use for stabilizing a simple agglomerate for pH and salt and with adjustable size. In phosphoric acid buffer solutions with different salt concentrations and pH values, the polyacrylic acid hydroxypropyl group condensation body has specific stability; hydrophobic thermal response blocks are introduced into a hydroxypropyl acrylate monomer through reversible addition-fragmentation chain transfer polymerization to regulate and control the size of a condensation body, and a phase separation behavior is shown at different temperatures; a hydrophobic block without thermal response is introduced to regulate and control the size of the aggregate, and no thermal response behavior is shown. Continuous regulation and control of the size of the aggregate from the micron level to the nano level are achieved, and the requirements of different application scenes are met. The hydroxypropyl polyacrylate condensation body can be used for packaging various dyes and drugs; high-efficiency enzyme protection is achieved, formed aggregates can protect glucose oxidase, and the retention rate of enzyme activity reaches 85% or above after treatment is conducted for 3 hours at 60 DEG C; as a micro-reactor for the reaction of generating p-nitrobenzaldehyde phenylhydrazone from p-nitrobenzaldehyde and phenylhydrazine, the reaction rate is greatly improved.

The application discloses a perovskite solar cell based on a 4-carboxyphenylhydrazine hydrochloride modified hole transport layer. A co-self-assembly monolayer is constructed by adding 0.05-0.20 mg / mL of 4-carboxyphenylhydrazine hydrochloride to a Ph-4PACz solution, and the co-assembly behavior of the 4-carboxyphenylhydrazine hydrochloride and the Ph-4PACz is utilized to inhibit the pi-pi stacking aggregation of rigid conjugated groups, repair the long-range ordered charge transport channel in the molecular layer, improve the hole extraction and transport characteristics, and at the same time, the 4-carboxyphenylhydrazine hydrochloride can synergistically passivate the uncoordinated Pb 2+ defects and deep energy level Pb 0 defects, reduce the interface non-radiative recombination loss, and improve the perovskite thin film crystallization quality. The application synchronously optimizes the charge transport characteristics and the interface passivation effect, significantly improves the photoelectric conversion efficiency and the device stability of the perovskite solar cell, and has certain guiding significance for manufacturing large-area perovskite solar cells.

This invention belongs to the field of medicinal chemistry, specifically relating to 2-[2-methyl-6-(quinoline-3-yl)nicotinyl]-N-phenylhydrazine-1-formamide derivatives, their preparation methods, and applications. This invention is the first to synthesize 2-[2-methyl-6-(quinoline-3-yl)nicotinyl]-N-phenylhydrazine-1-formamide derivatives. Furthermore, the preparation method for these derivatives features low raw material costs, high yield, and a simple and easily controllable reaction process, making it suitable for industrial production. Moreover, these derivatives exhibit high NR4A1 protein-level inhibitory activity and can be used to prepare anti-hepatocellular carcinoma drugs.

The invention belongs to the technical field of pesticide chemistry, and particularly relates to an application of a substituted phenylhydrazine copper salt complex as an agricultural fungicide, the structural general formula of the substituted phenylhydrazine copper salt complex is [Cu (ArNHNH2) 2] Xn, Ar is selected from 3-chlorphenyl-, 2, 4-dichlorophenyl-, 2, 4-dichlorophenyl-, 2, 4-dichlorophenyl-, 2, 4-dichlorophenyl-, 2, 4-dichlorophenyl-, 2, 4-dichlorophenyl-, 2, 4-dichlorophenyl-, 2, 4-dichlorophenyl-, 2, 4-dichlorophenyl-, the compound is prepared from 2, 6-dichlorophenyl, p-trichloromethoxyphenyl, 4-trifluoromethylphenyl, 4-trifluoromethoxyphenyl, 4-bromophenyl, 4-nitrophenyl, 4-cyanophenyl and 4-carboxyphenyl, and the compound is prepared from 2, 6-dichlorophenyl, p-trichloromethoxyphenyl, 4-trifluoromethylphenyl, 4-trifluoromethoxyphenyl, 4-bromophenyl, 4-nitrophenyl, 4-cyanophenyl and 4-carboxyphenyl. X is selected from SO4 <->, Cl <-> and NO3 <->; n is equal to 1-2. The substituted phenylhydrazine copper salt complex disclosed by the invention has remarkable inhibitory activity on plant pathogenic bacteria, has very high inhibition rate on three plant pathogenic fungi, namely fusarium graminearum, rhizoctonia solani and sclerotium rolfsii, can be used as a safe and efficient novel bactericide, and is applied to prevention and treatment of various crop diseases.

The present disclosure provides a reagent and a method for detecting paraquat in herbicide preparation, the reagent comprising reagent A, reagent B and reagent C, the reagent A being a solution prepared from dipotassium hydrogen phosphate and an alkaline buffer, the reagent B being methanol, and the reagent C being a solution of acetylphenylhydrazine. The method comprises mixing the herbicide preparation to be tested with the reagent A to form a uniform solution A, then adding the reagent B to the uniform solution A, shaking and waiting for phase separation, taking the supernatant B and adding it to the reagent C, immediately visually comparing the color or using a spectrophotometer to compare the color, and determining whether the herbicide preparation to be tested contains paraquat according to the color change. The present disclosure uses acetylphenylhydrazine as a reducing agent combined with solvent to control the redox potential of the reducing agent, develops a detection system specific for reducing paraquat, and applies it to the detection of latent ingredients in herbicide preparations, which has the characteristics of high detection sensitivity, convenient operation and obvious phenomenon, and is suitable for on-site detection.

The present application provides a method for preparing and using a graphene / poly N,N-diethylacrylamide hydrogel film electrode. The graphene / poly N,N-diethylacrylamide hydrogel film electrode is prepared by the preparation method provided by the present application. Phenylhydrazine is used as an active probe of environmental pollution molecules. The graphene / poly N,N-diethylacrylamide hydrogel film electrode exhibits pH, temperature, and salt-sensitive electrochemical responses and exhibits switch properties. Furthermore, the graphene / poly N,N-diethylacrylamide hydrogel film electrode is combined with phenylhydrazine molecular electrocatalysis, and the electrochemical catalytic oxidation of phenylhydrazine is controlled and regulated by utilizing the changes in various stimulating factors of the external environment, thereby realizing the monitoring and control of phenylhydrazine and the construction of a logic gate system.

The invention discloses a synthesis method of 1-(4-chlorphenyl) pyrazolidine-3-ketone, which comprises the following steps: by taking p-chlorophenylhydrazine hydrochloride and acrylamide as raw materials and toluene as a solvent, carrying out azeotropic dehydration under the normal pressure condition, cooling, adding flaky sodium hydroxide or potassium hydroxide, adding acrylamide, carrying out condensation reaction at 40-80 DEG C, filtering, washing and drying to obtain the 1-(4-chlorphenyl) pyrazolidine-3-ketone. And after the reaction is finished, acidifying, desolventizing, crystallizing and filtering to obtain the high-purity 1-(4-chlorphenyl) pyrazolidine-3-ketone. Compared with the prior art, the method provided by the invention has the following advantages: firstly, the inorganic base is adopted to replace the traditional sodium alkoxide organic base, so that the problems of flammability, danger and the like are avoided, and the reaction safety is greatly improved; process conditions are mild, operation steps are simplified, and repeated heating and cooling or negative pressure maintaining are not needed; and thirdly, the process is more environment-friendly, the molecular utilization rate is higher, by-products of alcohols are not generated compared with the traditional process, and the burden of sewage treatment is reduced. Sodium alkoxide is replaced by inorganic base, production cost is saved, and economic benefits are good.

The present invention provides an electrochemical catalytic synthesis method for phenidone, comprising the following steps: step (1), adding an electrolyte, phenylhydrazine, and acrylate to an organic solvent, then placing an anode electrode and a cathode electrode, and passing a direct current to perform an electrochemical catalytic reaction to obtain an intermediate 1; step (2), dissolving the intermediate 1 in an organic solvent, heating and refluxing under light-proof conditions to obtain a crude phenidone product; and step (3), recrystallizing the crude phenidone product to obtain a compound phenidone. The present invention utilizes an electrochemical method to study the reaction of phenylhydrazine and methyl acrylate. The reaction conditions are mild, the reaction occurs at room temperature, and the selectivity, yield, and safety are high. The method is a new method for synthesizing phenidone with high yield.

The present invention relates to the field of drug synthesis, and in particular to a synthesis process of celecoxib, comprising the following steps: the route uses A compound p-methylacetophenone, B compound 4-sulfonamidophenylhydrazine hydrochloride and C compound trifluoroacetaldehyde as starting materials, and obtains intermediate D compound through Mannich reaction under certain conditions. Under certain conditions, D compound undergoes intramolecular condensation reaction to obtain 2,3-dihydropyrazole intermediate products, and the 2,3-dihydropyrazole intermediate products are aromatized under the action of MnO2 or DDQ, and the target product celecoxib is obtained by "one pot method". A synthesis process of celecoxib provided by the present invention, the whole route is short and novel, the raw materials are cheap and easy to obtain, the reaction conditions are mild, economical and effective, and the yield is higher than the existing preparation method, and it is suitable for large-scale industrial production.

This invention discloses a method for preparing 4-(trifluoromethylsulfinyl)pyrazole compounds, comprising: dissolving terminal alkyne in n-hexane under nitrogen atmosphere, adding anhydrous zinc chloride, and reacting trifluoromethylsulfinyl chloride to obtain α-trifluoromethylalkynyl sulfoxide; adding benzoyl chloride dropwise to a CH2Cl2 solution of phenylhydrazine and triethylamine under nitrogen atmosphere to obtain acylhydrazine; adding carbon tetrachloride to a suspension of acylhydrazine and triphenylphosphine in acetonitrile to obtain hydrazone chloride; and reacting α-trifluoromethylalkynyl sulfoxide, hydrazone chloride, potassium carbonate, and anhydrous ethanol at room temperature to obtain 4-(trifluoromethylsulfinyl)pyrazole compounds. This invention uses inexpensive and readily available raw materials, the entire reaction route is mild and simple to operate, does not require stringent reaction conditions, and most of the reaction process is carried out at room temperature. The product yield is high, and the prepared trifluoromethylalkynyl sulfoxide pyrazole structure has multiple derivatization sites, showing good application prospects.

The invention discloses a diazotization anaerobic gel breaker for removing polyacrylamide micelles in strata and a preparation method of the diazotization anaerobic gel breaker, and relates to the technical field of oil exploitation. The diazotization anaerobic gel breaker for removing the polyacrylamide micelles in the stratum comprises an intermediate I and a mature body I, the intermediate I is a mixed solution of phenylhydrazine, carbamide, distilled water, acetone cyanohydrin and concentrated sulfuric acid, and the mature body I is a mixed solution of the intermediate I, hydrobromic acid and hydrogen peroxide. In the invention, the obtained diazotized anaerobic gel breaker has a diazo structure, and the diazo structure starts to decompose free radicals and release nitrogen under an acidic condition. The released free radicals have an oxidation effect and can gradually dissolve polyacrylamide micelles from outside to inside, the released nitrogen can tear the micelles from the inside, and meanwhile, the release of the nitrogen can increase the internal pressure of a crack space, so that the emission of the cracked micelles is facilitated, and the method has a wide application prospect.

The application discloses a preparation method and product of a myrtenyl-1,3,4-oxadiazole formylhydrazine compound and application of the compound, and synthesizes myrtenic acid by oxidizing myrtenal; myrtenyl hydrazine is generated by reacting the myrtenic acid with hydrazine hydrate; myrtenyl-1,3,4-oxadiazole methyl ester is generated by reacting the myrtenyl hydrazine with oxalyl chloride methyl ester; the myrtenyl-1,3,4-oxadiazole formylhydrazine compound is generated by reacting the myrtenyl-1,3,4-oxadiazole methyl ester with each substituted phenylhydrazine; the compound has a general formula I: wherein R is H, 4-F, 4-Cl, 4-Br, 4-I, 4-CH3, 2-CH3, 2-F, 3-F, 2-Cl, 3-Cl, 2-Br, 3-Br or 4-OCH3; the compound has good prevention effects on sclerotinia sclerotiorum, botryosphaeria dothidea and fusarium graminearum under an in-vitro condition, and can be used for preventing and treating fungal diseases of agricultural or forestry plants. The preparation method of the compound is simple, the yield is high, and the product is stable in property.

The invention discloses a COF nanosheet prepared through electrolysis and application of the COF nanosheet to preparation of hydrogen peroxide through electro-catalysis O2 reduction (ORR), and belongs to the technical field of covalent organic framework materials. Specifically, the condensation reaction of the covalent organic framework material is promoted by electrolyzing 1, 2-diphenylhydrazine to generate acid serving as a catalyst, the thickness of the obtained covalent organic framework material nanosheet can be accurately regulated and controlled, the prepared nanosheet has high crystallinity, the stability and orderliness of the material are improved, and the covalent organic framework material can be applied to the preparation of the covalent organic framework material. A more regular atomic arrangement and chemical bonding network is formed in the crystal structure, the prepared nanosheet also presents a porous structure, the pore channel distribution is uniform, and the pore size can be adjusted in a certain range. The COF nanosheet prepared by the method has good performance as an electrocatalyst, the formation and desorption of intermediate-state OOH * of ORR reaction are adjusted in alkaline electrolyte, electrocatalytic hydrogen peroxide production is promoted, the COF nanosheet shows very high catalytic performance, and the Faraday efficiency of hydrogen peroxide preparation is 90% or above.

The invention belongs to the technical field of emission reduction of nitrous oxide in soil, and particularly relates to application of hydroquinone type biochar in reduction of emission of nitrous oxide in soil, and the hydroquinone type biochar is applied to reduction of emission of nitrous oxide in soil. The preparation method of the hydroquinone type biochar comprises the following steps: S1, mixing p-benzoquinone and straws, and pyrolyzing in a heating furnace to prepare quinone / hydroquinone type biochar; s2, phenylhydrazine and hydrochloric acid are dissolved in ethyl alcohol, then the quinone / hydroquinone type biochar is added and stirred, then precipitates are separated and washed with ethyl alcohol, and the hydroquinone type biochar is obtained after drying. The hydroquinone type biochar containing quinone groups is prepared and applied to N2O emission reduction of soil, the hydroquinone type biochar serves as an electron shuttle, N2O is promoted to be converted into N2, and the N2O emission reduction amplitude can reach 60%-90%.

The invention provides an electrochemical catalytic synthesis method of phenidone, which comprises the following steps: step (1), adding electrolyte, phenylhydrazine and acrylate into an organic solvent, then putting into an anode electrode and a cathode electrode, and electrifying direct current to carry out electrochemical catalytic reaction to obtain an intermediate 1; (2) dissolving the intermediate 1 in an organic solvent, and heating and refluxing under a dark condition to obtain a phenidone crude product; and (3) recrystallizing the phenidone crude product to obtain the compound phenidone. The reaction of phenylhydrazine and methyl acrylate is researched by utilizing an electrochemical method, the reaction condition is mild, the reaction is performed at room temperature, the selectivity is high, the yield is good, the safety is high, and the method is a novel method capable of synthesizing the phenidone at high yield.

The application belongs to the technical field of molecular biology and drug screening, and provides a method for screening phenylhydrazine sulfate based on a key binding amino acid site of SOCS5-CP and application thereof, which comprises the following steps: key amino acid sites of SOCS5-CP binding are screened through alanine virtual point mutation, and a binding pocket is determined; a ligand molecule is used to perform virtual screening by taking the binding pocket as a docking area, and a compound with the best binding energy is obtained; the obtained drug is screened through AMDET; the selected compound is used for subsequent in-vitro cell experiments, and further screening is performed; the application uses the method of molecular docking and virtual screening in combination with in-vitro experiments for screening, and finds that phenylhydrazine sulfate can be stably combined at the key amino acid sites of SOCS5-CP, in-vitro experiments show that phenylhydrazine sulfate can effectively inhibit the binding of SOCS5-CP, and further down-regulate the protein expression level of HIF1a in hepatoma cells, and also has a significant inhibitory effect on the invasion and migration ability of primary hepatocellular carcinoma.

The application discloses a preparation method of sulfentrazone intermediate, which comprises the following steps: in a solvent, substitution ring-closing reaction of cis-trans isomer compound (nitro hydrazone) shown in formula II and cyanate salt is carried out to generate sulfentrazone intermediate shown in formula III. The scheme provided by the application solves the problems in the prior art, such as the use of a large amount of inorganic reducing agent, such as sodium sulfite, in the production of raw material phenylhydrazine for preparing triazolinone through phenylhydrazine, generation of a large amount of solid waste, and low atomic economy; the scheme solves the problems in the prior art, such as the use of a large amount of sulfite reducing agent and sodium hypochlorite oxidant in the production of raw material phenylhydrazine for preparing triazolinone through phenylhydrazine, generation of a large amount of mixed salt, and low chloro-substitution selectivity of sulfentrazone prepared by using phenylhydrazine as raw material; the scheme solves the problems, such as the reduction of diazonium salt to hydrazine, the oxidation of hydrazine to hydrazine, and the like; the scheme directly utilizes intermediate hydrazine and then utilizes cyanate salt ring-closing, and compared with the prior art, the scheme is shortened by 3 steps, and energy consumption and labor intensity are greatly reduced.

The invention provides a suspending agent containing cyflumetofen and bifenazate, which is characterized by comprising the following components in percentage by mass: 15-25% of cyflumetofen, 15-25% of bifenazate, 2-4% of dispersing agent, 2-4% of wetting agent, 0.5-1% of thickening agent, 3-6% of stabilizer, 3-7% of antifreezing agent, 0.5-0.8% of defoaming agent and the balance of water. According to the suspending agent containing cyflumetofen and bifenazate provided by the invention, the dispersing agent, the wetting agent and the thickening agent are screened and matched with the specific stabilizer, so that the stability and the control effect of the cyflumetofen-bifenazate suspending agent are remarkably improved on the basis that various indexes meet the standard of a qualified suspending agent.

The application belongs to the technical field of microbial preparation of compounds, and provides a phenylhydrazine compound, which has an excellent inhibitory activity on Candida albicans.

The invention belongs to the field of organic chemical synthesis, and relates to a method for synthesizing a natural product Pyrroloazocine indole alkaloid skeleton. According to the method, a commercially available compound 1 and phenylhydrazine are taken as synthesis starting points, and a [2.2. 2] bridge ring system is constructed through key Fischer indole synthesis, Stille coupling reaction and intermolecular Diels-Alder reaction. The preparation method comprises the following steps: carrying out a cyclopropanation reaction mediated by carbene, carrying out a Ley-Griffith oxidation reaction, and carrying out a Beckmann rearrangement and an intramolecular SN2 cyclization cascade reaction so as to realize the construction of the core skeleton of the Pyrroloazocine indole alkaloid. According to the method, a material basis can be provided for activity testing of the Pyrroloazocine indole alkaloid and the analogue thereof, and a thought is provided for synthesis route design of more complex cage-shaped indole alkaloid basic frameworks.

The utility model discloses a kind of phenylhydrazine wastewater treatment resource use grading heat exchange devices, it is related to wastewater treatment technical field, including outlet and filtering recovery mechanism, the one end of the outlet is fixedly connected with filtering recovery mechanism, and filtering recovery mechanism includes recovery tank fixedly connected in the outlet one end position, the inside fixedly connected with glass fibre composite layer of the recovery tank, and the inside of recovery tank is provided with polytetrafluoroethylene layer, the inside of the recovery tank is provided with resin adsorption filter core, and the top of resin adsorption filter core is provided with impurity filter screen, and recovery tank is outer layer carrier. The phenylhydrazine wastewater treatment resource use grading heat exchange device, compared with existing ordinary wastewater heat exchange device, enhances the impact resistance of box, corrosion resistance, realizes double separation, makes wastewater in standard discharge convenient recycling, and improves heat conduction efficiency, forms waste heat recovery closed loop, improves energy efficiency and resource utilization rate, and supports device management efficiency.

The invention provides a synthesis method of a hydrogen storage material N-ethyl carbazole, and the synthesis method of the hydrogen storage material N-ethyl carbazole comprises the following steps: step 1, preparing an intermediate tetrahydrocarbazole; step 2, preparing a liquid product, and step 3, sequentially adding 53-76.5 parts of the liquid product prepared in the step 2, 213-320 parts of a solvent o-dichlorobenzene and 0.8-1.2 parts of 5% platinum / carbon into a three-neck flask provided with a reflux condenser, heating to reflux, and keeping the temperature for 1 hour; reacting, cooling to 80 DEG C, filtering, adding 26.5-40 parts of a hot solvent to wash the catalyst, and carrying out reduced pressure distillation to recover the solvent, so as to obtain a product N-ethyl carbazole; 4, adding 3-6 parts of N-ethyl carbazole prepared in the step 3, a proper amount of a solvent and 1-2 parts of an organic framework material into a reaction kettle, reacting for 8-12 hours at 120 DEG C by adopting a solvothermal method, cooling to room temperature after the reaction is completed, filtering, washing and drying to obtain a product hydrogen storage N-ethyl carbazole; a Fisher carbazole synthesis method is adopted, phenylhydrazine and cyclohexanone are used as raw materials, 1, 2, 3, 4-tetrahydrocarbazole is obtained through condensation and closed loop, an N-tetrahydrocarbazole intermediate is obtained through ethylation reaction, and the high-purity hydrogen storage material N-ethyl carbazole is obtained through dehydrogenation.

The invention belongs to the technical field of phenylhydrazine production, and discloses a metering device for phenylhydrazine production and a metering method thereof.The metering device comprises a metering tank, a feeding port is formed in the bottom end of the metering tank, the outer side face of the metering tank is fixedly sleeved with a rack, and a quantitative limiting assembly is movably sleeved with the metering tank; the top end of the quantitative limiting assembly is movably clamped with a quantitative adjusting assembly, and the bottom end of the quantitative adjusting assembly is provided with an auxiliary measuring assembly. The quantitative limiting assembly and the quantitative adjusting assembly are matched and utilized, that is, after pre-adjustment is carried out through the quantitative adjusting assembly, the maximum rising distance of the piston plate is limited through buoyancy provided by injected raw materials and the effect of the quantitative adjusting assembly, and the quantitative limiting assembly and the quantitative adjusting assembly are matched and used for limiting the maximum rising distance of the piston plate. According to the device, the overall volume of the metering tank can be adaptively adjusted, the quantitative feeding requirements in different scenes are met, quantitative feeding can be completed without replacing metering tanks of different specifications, and the overall practicability of the device is improved.

The invention relates to a hole transport layer, a perovskite solar cell and a preparation method, and the method sequentially comprises the following steps: providing a substrate, and preparing a composite hole transport layer on the substrate; depositing an inorganic salt thin film on the composite hole transport layer by adopting a vacuum evaporation method; spin-coating an organic salt solution on the inorganic salt thin film, and then annealing to form a perovskite light absorption layer; preparing a passivation layer on the perovskite light absorption layer; and preparing an electron transport layer, a hole blocking layer and a back electrode in sequence to complete cell preparation. According to the invention, by introducing a'common SAMs' technology (that is, 3, 5-bis (trifluoromethyl) phenylhydrazine hydrochloride is doped into Me-4PACz), the surface property of the hole transport layer is fundamentally improved, and the interface property and the crystallization quality of the thin film are optimized.

This invention relates to the field of chemical synthesis technology, specifically a method for preparing 2,3,3,5-tetramethylindole. The method comprises using p-methylphenylhydrazine hydrochloride and 3-pentanone as raw materials, generating 2,3,3,5-tetramethylindole through a one-step condensation-cyclization reaction in acetic acid medium, followed by further processing steps. This synthetic method offers significant advantages: First, it is highly efficient, with a one-step condensation-cyclization reaction, a molar yield of 60-68%, HPLC endpoint control, and a total processing time of one day, making it suitable for industrial production. Second, it operates under mild conditions, using acetic acid as both solvent and catalyst, with a reaction temperature of 112℃, allowing the use of ordinary enamel-lined reactors and avoiding corrosion from traditional strong acid equipment. Third, it achieves excellent purity, with no isomers and a purity exceeding 99%, offering flexible purification at low cost. Fourth, it is more environmentally friendly, with a dichloromethane recovery rate ≥90%, and wastewater with a near-neutral pH for easy treatment. Fifth, it is easily scaled up, with quantitative formulas for parameters and flexible process adjustments, adaptable to various production fields.