10 results about "Dimethyl glutarate" patented technology

SOLVENT COMPOSITIONS The present invention relates to a solvent composition for solvent-based paints or other coatings characterized in that it comprises a combination of dimethyl glutarate and at least one other compound selected from isobutyl acetate, ethyl lactate, dimethyl 2-methylglutarate, 2-methyltetrahydrofuran, ethyl acetate, cyclopentyl methyl ether, dithoxymethane, dimethyl carbonate, dimethyl succinate, benzyl alcohol, dimethyl adipate, and glyceryl triacetate. Fig. 1

This invention provides a continuous preparation method for dimethyl 2-methylglutarate, carried out in a first microchannel reactor and a second microchannel reactor connected in series. The method includes: feeding 2-methylglutaronitrile and sulfuric acid solution into the first microchannel reactor for hydrolysis; and contacting them with methanol in the second microchannel reactor for esterification. The esterified material is then subjected to phase separation to obtain dimethyl 2-methylglutarate. The mass ratio of 2-methylglutaronitrile to sulfuric acid solution is 1:(5~20). The controlled temperature of the first microchannel reactor is 80~120℃; the controlled temperature of the second microchannel reactor is 65~105℃, and the controlled temperature of the second microchannel reactor is not higher than that of the first microchannel reactor; the mass ratio of 2-methylglutaronitrile to methanol is 1:(1~6). Through the synergistic operation of the microchannel reactor and multiple control parameters, the eutectic precipitation of intermediate products with ammonium sulfate can be avoided, clogging can be prevented, and efficient, high-yield continuous preparation can be achieved.

The invention discloses a preparation method of 2, 4-bis [2-(6-trifluoromethylpyridine-2-oxymethyl) phenyl] dimethyl glutarate. The 2, 4-bis [2-(6-trifluoromethylpyridine-2-oxymethyl) phenyl] dimethyl glutarate is used as a raw material. 2, 4-bis [2-(6-trifluoromethylpyridine-2-oxymethyl) phenyl] dimethyl glutarate is taken as an associated impurity in the synthesis process of picoxystrobin, and the prepared high-purity impurity standard sample has important significance on registration of picoxystrobin at home and abroad and qualitative and quantitative impurity and process optimization in the research and development process. At present, the compound 2, 4-bis [2-(6-trifluoromethylpyridine-2-oxymethyl) phenyl] dimethyl glutarate is not reported in literatures, and a preparation method of the compound is not provided. According to the method, a picoxystrobin key intermediate 2-(6-trifluoromethylpyridine-2-oxymethyl) phenyl methyl acetate is taken as a raw material and reacts with paraformaldehyde under the action of strong base to generate a crude product, and finally, a pure product of the compound is obtained through column chromatography.

The present invention relates to an anisotropically conductive heat activated adhesive composition, comprising a) one or more thermoplastic resin; b) metal coated particles; and c) a solvent selected from the group consisting of l-methoxy-2- propanylacetate,2-butoxyethyl acetate, 2-(2-butoxyethoxy)ethanol, [2-(2-butoxyethoxy)-ethyl]acetate, 2-butoxyethanol, isophorone, 3, 3, 5-trimethyl-2-cyclohexene-l-one, dimethyl succinate, dimethyl glutarate, dimethyl adipate, acetic acid, l-methoxypropan-2-ol, 1- methoxy-2-propylacetat, dipropylene glycol (mono)methylether, toluene, ethanol, isopropyl alcohol, n-propanol, ethoxy propanol, ethylacetate, butyl acetate, n-propyl acetate, isopropyl acetate, methyl ethyl ketone, methyl isobutyl ketone, glycol ethers and mixtures thereof, wherein the one or more thermoplastic resin is dissolved into the solvent. The composition can be used in electronic devices.

The application relates to the technical field of electronic equipment, in particular to an ink, a preparation method thereof, a camera decoration assembly, a shell and an electronic equipment. The ink comprises a main agent, a pigment filler, a diluent and a curing agent; the main agent comprises a main body resin, and the main body resin comprises the following components in parts by mass: 60-80 parts of methyl methacrylate; 1-3 parts of bisphenol A diglycidyl ether; and 6-10 parts of dimethyl glutarate. The above ink can solve the problem that ultraviolet light cannot penetrate the shielding layer to cure the ultraviolet curing glue.

The application discloses a kind of green enzymatic polycondensation synthesis polyamide 6,5 method, with dimethyl glutarate and 1,6-hexanediamine as raw material, using Novozym435 immobilized lipase as biological catalyst, by direct enzymatic polycondensation reaction preparation biobased polyamide 6,5.The method uses toluene as reaction medium, combined with vacuum by-product, molecular sieve water absorption balance control strategy, realizes the green efficient synthesis of polyamide 6,5, product has excellent thermal stability (melting point 221 DEG C, maximum decomposition temperature 434 DEG C), suitable for melt spinning and other industrial processes, compared with traditional chemical synthesis method, greatly reduce energy consumption, reduce the use of toxic chemicals, provide a new way for the green manufacturing of polyamide.

The present invention relates to the field of chemical drug synthesis, and specifically discloses a preparation method of a nirmatrelvir intermediate, which comprises the following steps: (1) The raw material (2S,4R)-2-((tert-butoxycarbonyl)amino)-4-(cyanomethyl)dimethyl glutarate is subjected to a reduction cyclization reaction under the action of a potassium borohydride / cobalt chloride system, and then undergoes post-treatments such as extraction washing, concentration and recrystallization to obtain compound (Ⅱ); (2) An ammonolysis reaction is carried out at a relatively low temperature in an ammonia methanol solution, and then filtration is carried out to prepare an isopropanol solution of compound (Ⅲ); (3) Acetyl chloride is dropped into isopropanol to prepare an isopropanol solution of hydrogen chloride, and compound (Ⅲ) is added to the prepared isopropanol solution of hydrogen chloride. A deprotection and salt formation reaction is carried out at a low temperature, and the product precipitates. Filtration and drying are carried out to obtain a high-purity finished compound (Ⅳ), which is the nirmatrelvir intermediate.

The application discloses a preparation method of 2-methyl glutaric acid dimethyl ester, which comprises the following steps: taking methyl acrylate as a starting material, firstly adding to obtain an intermediate 2-methylene glutaric acid dimethyl ester, and then catalytically hydrogenating to obtain 2-methyl glutaric acid dimethyl ester; the catalyst used in the addition reaction is a composite catalyst of tributyl phosphine and 18-crown-6 ether-6; the amount of tributyl phosphine is 1-10% of the weight of methyl acrylate; the amount of 18-crown-6 ether-6 is 0.1-5% of the weight of methyl acrylate; and the molar ratio of tributyl phosphine to 18-crown-6 ether-6 is 1:0.1-1:0.3. The addition reaction of the application adopts a composite catalyst composed of a small amount of 18-crown-6 ether-6 and tributyl phosphine; the composite catalyst has high catalytic activity, can obtain high reaction conversion rate, and has low by-product content, so that the reaction yield is high; in particular, the price of the composite catalyst is obviously lower than that of a diamino phosphine catalyst, so that the production cost is obviously reduced.

The invention discloses an anti-aging biodegradable material and a preparation method thereof, and relates to the technical field of high polymer materials. When the anti-aging biodegradable material is prepared, rutin and ethyl chlorophosphate epoxypropyl ester react to prepare modified rutin; the preparation method comprises the following steps: polymerizing ionone dimethyl glutarate, alpha-hydroxyl-omega-carboxyl oligomeric lactic acid, 1, 6-hexanediol and 3-(1H-imidazole-1-yl) propane-1, 2-diol to obtain oligomeric lactic acid copolyester; the straw powder and 4-(1, 1, 1, 3, 5, 5, 5-heptamethyltrisiloxan-3-yl) butyl chloride are subjected to a reaction, and modified straw powder is prepared; and uniformly mixing the oligomeric lactic acid copolyester, the modified straw powder and the modified rutin, and performing injection molding in an injection molding machine to obtain the anti-aging biodegradable material. The anti-aging biodegradable material prepared by the invention has excellent anti-aging, flame-retardant and mechanical properties.

An aqueous suspension or colloid composition comprising dimethyl glutarate, a further dialkyl ester which is not a sugar ester or dimethyl glutarate, a glycoside surfactant, an essential oil, and a su