36 results about "Sulfohydrazide" patented technology

The invention discloses a perovskite solar cell doped with a sulfonyl hydrazide foaming agent and a preparation method thereof, and belongs to the field of photovoltaic power generation, a perovskite light absorption layer is FA1-x-yMAxCsyPb (I1-zBrz) 3 doped with the sulfonyl hydrazide foaming agent, x is equal to 0-1, y is equal to 0-1, and z is equal to 0-1. The sulfonyl hydrazine foaming agent interacts with uncoordinated Pb < 2 + > and I <->, and the sulfonyl hydrazine foaming agent is decomposed in the thermal annealing process to induce crystal grains to realize secondary fusion growth, so that defects in the perovskite light absorption layer are effectively passivated, recombination of photon-generated carriers of the perovskite solar cell is reduced, and the photoelectric conversion efficiency of the perovskite solar cell is improved. The open-circuit voltage, the fill factor and the photoelectric conversion efficiency of the perovskite solar cell are obviously improved, and the device efficiency PCE exceeds 26%; according to the preparation method provided by the invention, the p-i-n inversion structure device is prepared by spin coating through a one-step method, the preparation process is simple and convenient, and the cost is low.

The application provides a reverse Markovnikov hydroamination reaction of trifluoromethyl enone under catalyst-free and base-free conditions, uses a sulfonhydrazide compound with good functional group tolerance as a nitrogen source, realizes the introduction of a nitrogen-containing functional group in a green and environment-friendly manner, and synthesizes a series of alpha-sulfonhydrazine-alpha-hexafluoroisopropyl-substituted carbonyl compounds. The method has the characteristics of no transition metal participation, mild conditions, wide substrate universality and the like.

The invention relates to a thermally expandable composition comprising: a) At least one thermoplastic polymer TP and / or at least one solid rubber R and b) At least one polymeric blowing agent BA selected from the group consisting of sulfonyl hydrazide-functionalized polymers, sulfonyl semicarbazide-functionalized polymers, carbamate-functionalized polymers, and ureido carbamate-functionalized polymers, wherein the polymeric blowing agent BA has a number average molecular weight (Mn) determined by gel permeation-chromatography (GPC) using polystyrene 0 as standard of at least 500 g / mol, preferably at least 750 g / mol.

The application belongs to the technical field of polyvinyl chloride foam material preparation, and particularly relates to a polyvinyl chloride foam material for offshore operation and a preparation method thereof. The polyvinyl chloride foam material for offshore operation comprises polyvinyl chloride resin as a base resin, silane-modified aluminum borate nanometer whisker, 1-(9,10-epoxy octadecanoyloxy)-3-(2-methylprop-2-enoyloxy)propan-2-ol and oleic acid-modified Mg-Al-Zn ternary intercalation hydrotalcite as modified raw materials, 4,4'-diphenyl methane diisocyanate and 4,4'-dicyclohexyl methane diisocyanate are compounded to construct a soft and hard synergistic crosslinking network, azodicarbonamide, benzene-1,3-disulfonyl hydrazide and zinc oxide are compounded to form a foaming agent to realize gradient nucleation foaming, and a heat stabilizer, a light stabilizer and an antioxidant are further added. As a result, the synergistic effect between the raw materials enables the polyvinyl chloride foam material to have excellent salt mist resistance and impact resistance.

The invention relates to a method for preparing 1, 2-bis (4-vinylphenyl) ethane, and relates to the technical field of organic chemistry, the preparation method comprises the following steps: (1) mixing a compound 1, p-toluenesulfonhydrazide and an organic solvent 1, and reacting to obtain a compound 2; and (2) reacting the compound 2 in an organic solvent 2 under the action of alkali and a polymerization inhibitor to generate the 1, 2-bis (4-vinyl phenyl) ethane. The method is mild in reaction condition, simple and convenient to operate, high in product purity, high in yield and suitable for industrial production.

The invention relates to the technical field of yoga mat production, in particular to a uniformly foamed yoga mat and a preparation method thereof, polyvinyl chloride resin is used as a main component, and polyformaldehyde resin and polymethyl methacrylate resin are added as reinforcing components; the wear resistance, the elasticity, the heat resistance, the cold resistance and the corrosion resistance of the traditional PVC yoga mat can be improved; moreover, aiming at the mixed raw material of the polyvinyl chloride resin, the polyformaldehyde resin and the polymethyl methacrylate resin, three foaming agents with different decomposition temperatures, namely toluenesulfonyl hydrazide, di (benzenesulfonyl hydrazide) ether and p-toluenesulfonyl semicarbazide, are added, and three stages are set in the foaming stage, so that the foaming performance of the polyvinyl chloride resin, the polyformaldehyde resin and the polymethyl methacrylate resin is improved. Different foaming temperatures and foaming time are controlled in each stage, so that the mixed raw materials can be foamed more sufficiently, the foaming of the foaming materials is ensured to be more uniform, and the quality of the yoga mat is improved.

The application relates to the technical field of pharmaceutical chemistry, and discloses a sulfuryl hydrazone compound, a preparation method thereof and anti-tumor application. The compound is synthesized from isatin derivatives and sulfuryl hydrazine through two-step nucleophilic substitution-elimination reaction, has a chemical structure as shown in formula (I), and is characterized by 1H NMR, 13C NMR and HRMS. The sulfuryl hydrazone compound has significant inhibitory activity on A549 (lung cancer), HepG2 (liver cancer) and Hela (cervical cancer) three human cancer cell strains, the value of some compounds is as low as 0.03 micromole / L, the compound can induce cell apoptosis by mediating ROS generation in tumor cells, inhibiting the NF-kappa B signal pathway and activating Caspase-3 activity, and can effectively inhibit cancer cell migration and colony formation. The compound has a mild synthesis process, simple operation and wide substrate applicability, can be used as a potential anti-tumor active ingredient, can be used for preparing drugs for resisting lung cancer, liver cancer, cervical cancer and other tumors, and can provide new candidate compounds and technical support for cancer treatment.

This invention discloses a method for preparing high-performance tin-containing perovskite solar cells using bifunctional acylhydrazide small molecules. The method focuses on selecting bifunctional acylhydrazide small molecules such as p-toluenesulfonylhydrazide (PTSH) and oxaloyl dihydrazide (ODZ) as additives to enhance the performance of tin-containing perovskite (ASn) solar cells. x Pb 1‑x X3) Modification of the active layer of solar cells. Compared to traditional Sn 2+ The coordination strategy of the bifunctional hydrazide small molecule selected in this invention can, in addition to coordinating with Sn... 2+ In addition to providing an antioxidant environment through coordination, Sn can also achieve... 4+ To Sn 2+ The reduction of Sn in perovskite films can be minimized. 4+ This leads to the P-type self-doping effect and defect density. The photoelectric conversion efficiency and device stability of the tin-containing perovskite solar cells prepared based on this invention are effectively improved.

The invention relates to a process for producing polyurethanes using a component A comprising a polyhydrazide, a polysemicarbazide, a polysulfonyl hydrazide and / or carbodihydrazide, in particular a polyhydrazide, wherein the component A is employed in the form of a mixture C which further comprises a component B comprising a dispersion medium.

This invention discloses the preparation and application of an oxygen-modified carbon catalyst with adjustable surface carbon group number. The catalyst is prepared by using Ketjen black as a carbon substrate and ethylenediaminetetraacetic acid as an oxygen source, through stepwise oxygen addition (including surface oxidation and pyrolysis of oxygen-containing precursors) to modify the carbon substrate, thus obtaining the target catalyst. The number (concentration) of carbonyl groups at activated persulfate sites on the catalyst surface can be controlled by adjusting the pyrolysis temperature or by modifying the surface with glutaraldehyde or / and dansyl hydrazine. This concentration change causes an electron distribution between adjacent carbonyl groups, i.e., the intersitu spacing effect; utilizing this effect, efficient purification of water bodies contaminated with organic pollutants and effective soil remediation can be achieved.

The invention discloses a composite sewage treatment agent as well as a preparation method and application thereof, and relates to the technical field of water treatment. When the composite sewage treatment agent is prepared, firstly, 1, 3, 6, 8-pyrene tetrasulfonic acid tetrasodium salt is treated through thionyl chloride and then reacts with hydrazine hydrate to obtain pyrene sulfonyl hydrazide, and oxidized cellulose, pyrene sulfonyl hydrazide and polyethylene glycol react to obtain porous cellulose; secondly, reacting the maleic anhydride esterified starch with 4-mercaptophthalonitrile, then carrying out ammonia gas treatment, and then reacting with boron chloride subphthalocyanine to obtain modified starch; finally, mixing the modified cellulose, the modified starch and an initiator to obtain the composite sewage treatment agent. The composite sewage treatment agent prepared by the invention has good adsorbability, antibacterial property and photocatalytic degradation property.

The invention belongs to the technical field of organic synthesis, and particularly relates to a benzenesulfonyl hydrazide derivative, a preparation method and application. Under electrochemical reaction conditions, cheap and easily available ketone, benzenesulfonyl hydrazide and corresponding sodium benzenesulfinate are used as raw materials, acetonitrile (CH3CN) / water (H2O) is used as a solvent, triethylamine (Et3N) is used as alkali, the benzenesulfonyl hydrazide derivative is prepared at room temperature and in an air atmosphere, and the benzenesulfonyl hydrazide derivative has potential medicinal value and is widely applied to the fields of pesticides and medicines. Compared with a previously reported preparation method, the method has the advantages of being green, environmentally friendly, safe, efficient and energy-saving, raw materials are easy to obtain, operation is easy and convenient, and potential industrial application prospects are achieved.

The invention relates to the technical field of vitamin intermediates, and particularly discloses a preparation process of a vitamin D3 key intermediate 7-p-toluenesulfonyl epide-3-cholesteryl ester. The invention relates to a preparation process of a vitamin D3 key intermediate 7-p-toluenesulfonylepide-3-cholesteryl ester, which comprises the following steps: reaction: adding 7-keto-3-cholesteryl ester, p-toluenesulfonhydrazide and concentrated hydrochloric acid into methanol, heating to 45-50 DEG C, and carrying out heat preservation reaction for 6.5-7.5 hours; post-treatment: after the reaction is finished, cooling crystallization and suction filtration are performed to obtain a solid, the solid is eluted by using iced methanol, suction drying is performed to obtain a washing solution and a filter cake, and the filter cake is subjected to vacuum drying to constant weight to obtain the product 7-p-toluenesulfonylepide-3-cholesteryl ester. The concentrated hydrochloric acid is used as a catalyst, and the reaction is carried out at 45-50 DEG C for 6.5-7.5 h, so that the reaction is mild, the energy consumption is reduced, and the production efficiency of the 7-p-toluenesulfonylepide-3-cholesteryl ester is improved.

The invention discloses a (2, 3-indoline-(thio) carbonyl) substituted sulfonyl hydrazide compound as well as a preparation method and application of the (2, 3-indoline-(thio) carbonyl) substituted sulfonyl hydrazide compound. The structural formula is shown as a formula I. The N '-(2, 3-indoline-1-(thio) carbonyl) substituted sulfonyl hydrazine compound is obtained by introducing a sulfonyl fragment into a substituted benzaldehyde semicarbazone (thio) urea skeleton containing a 2, 3-indoline-1-(thio) carbonyl fragment, and the N'-(2, 3-indoline-1-(thio) carbonyl) substituted sulfonyl hydrazine compound is novel in structure, the preparation method is simple to operate, raw materials are easy to obtain, and harmful by-products are not easy to generate; the compound disclosed by the invention shows an inhibition effect on various plant pathogenic bacteria, particularly has an obvious inhibition effect on cucumber bacterial angular leaf spot bacteria, can be used as an agricultural bactericide, and has a great application value.

The invention discloses a method for synthesizing a thiosulfonate compound through aerobic oxidative coupling, and relates to the technical field of organic synthesis.The synthesis method comprises the steps that a nitrogen-doped carbon-loaded cobalt-based catalyst is adopted, and in the oxygen or air atmosphere, a sulfydryl-containing compound and sulfonyl hydrazide are catalyzed to be subjected to an oxidative coupling reaction; the preparation process of the catalyst comprises the following steps: reacting cobalt salt with sodium dicyandiamide in a water phase to generate a dicyandiamide cobalt complex; mixing the complex with an ionic liquid containing dicyandiamide anions in proportion, stirring and drying to obtain an ionic liquid precursor of metal cobalt; and carbonizing the obtained precursor at a high temperature of 500-1000 DEG C in an inert atmosphere, etching for 2-10 hours by using a 1-6 mol / L hydrochloric acid solution, washing to be neutral, and drying to obtain the nitrogen-doped carbon-loaded cobalt-based catalyst. The catalyst used in the method is green, economical and recyclable, the reaction process is mild in condition and simple and convenient to operate, the product yield is excellent, and the method has a good application prospect.

The application discloses a method for sulfonylating halogenated quinoline and aryl sulfonohydrazide, wherein the halogenated quinoline compound and the aryl sulfonohydrazide are subjected to a sulfonylating reaction in a solvent to obtain a target compound. The application provides a simple method for forming a sulfonyl quinoline without adding any catalyst and additive, and the method is green and environment-friendly, and the reaction condition is simple and mild, and the method has the characteristics of simple post-treatment, green step, low pollution, high economic benefit and the like.

The application provides a self-repairing stretch silver paste, a preparation method and application thereof.The self-repairing stretch silver paste comprises the following raw materials: conductive silver paste, pore-forming agent and silicon modified resin; and the pore-forming agent is at least one of p-toluenesulfonyl hydrazide, sodium bicarbonate, molecular sieve and 4,4'-oxobenzene sulfonyl hydrazide.The self-repairing stretch silver paste of the application comprises the pore-forming agent and the silicon modified resin in addition to the conventional conductive silver paste, so that the silver paste can form an elastic conductor with porous cavities after gradient curing, the displacement of the conductive filler is reduced through the stress deformation of the cavities, the resistance recovery hysteresis is significantly improved, and the resistance deterioration is reduced; the obtained silver paste has fast resistance recovery speed, low hysteresis and excellent conductive stability under 50% stretch deformation, and is suitable for repeated deformation scenes such as flexible sensors, wearable devices and flexible circuits.

The invention discloses a preparation method of a thiocarbamate compound. According to the method, an isocyanide compound and a sulfinic acid compound are used as raw materials, and a series of target products are conveniently prepared under the condition of an oxidizing agent. The method disclosed by the invention has the advantages of cheap and easily available raw materials, mild reaction conditions, very simple reaction system, convenience in operation, good substrate universality, high target product yield, safe production and environmental friendliness, and is suitable for industrial production. According to the process, sulfinic acid compounds are used as raw materials, so that the unpleasant smell of thioether and mercaptan and the hidden danger of safe production in the prior art are avoided; meanwhile, a series of problems that thiosulfonate, sulfonyl hydrazide and the like need to be prepared in advance, the technological process is tedious and the like are solved.

The present invention discloses a preparation method of a polycyclic ketone derivative, which is obtained by adding a cyano-containing 1,6-enyne compound and a sulfonylhydrazide compound into a reactor, then adding a solvent and an oxidant, and after the reaction is complete, separating and purifying. The present invention only needs one step to construct four new chemical bonds and form two new rings, providing a new method for synthesizing polycyclic ketone derivatives. Moreover, this method does not require the use of a catalyst and a base, greatly reducing the manufacturing cost; and the substrate has a wide adaptability range, the operation is simple, the reaction is green and mild, and it is particularly suitable for industrial production.

The invention discloses a method for preparing deoxycholic acid. Specifically, the preparation method comprises the following steps: step 1, in the presence of a solvent and N-bromosuccinimide, carrying out oxidation reaction on a compound 2 to prepare a compound 3; 2, under the condition of a solvent, the compound 3 and p-toluenesulfonhydrazide are subjected to a condensation reaction, and a compound 4 is prepared; 3, in the presence of a solvent and sodium borohydride, the compound 4 is subjected to a reduction reaction, and deoxycholic acid is prepared. The method is mild in reaction condition, environmentally friendly, high in efficiency, low in cost and suitable for industrial production.

The present invention discloses a β-ketosulfone compound and a synthesis method thereof, belonging to the field of chemical synthesis technology. The present invention uses an enol ester compound and a sulfonylhydrazide compound to synthesize the β-ketosulfone compound through electrochemical redox catalysis. This method has the advantages of being green, sustainable, highly efficient, and using mild conditions, and avoids the use of additional oxidants or reducing agents.

The application discloses a novel and efficient electrochemical catalytic synthesis of sulfone isoxazole derivatives. The method uses beta, gamma-unsaturated ketone oxime and p-toluenesulfonyl hydrazine as starting materials, under the condition of C(+) / C(-) as an electrode, a current of 10 mA, and reaction at room temperature for 4 h, the oxidation sulfonation reaction of the alkenyl oxime substrate can be smoothly realized, and sulfone isoxazole derivatives are obtained. The sulfone radical is generated by anodic single electron oxidation of p-toluenesulfonyl hydrazine, then the radical addition is carried out on the alkenyl oxime, the benzyl radical is generated, then the radical oxidation reaction of the benzyl position and the intramolecular nucleophilic cyclization reaction are further carried out at the anode to generate the sulfone isoxazole product. Compared with the traditional synthesis scheme, the application only needs to add inorganic electrolyte as a conductive medium under mild conditions, without the addition of metal and additional oxidants, and the sulfone group can be introduced into the skeleton of the isoxazole ring under the electrochemical condition, and the aryl alkyl sulfone compound constructed is widely used in medicines, biologically active products and materials, and has important biological and synthetic research value.

The invention discloses a synthesis method of 2, 4, 5-trifluorophenylacetic acid, and relates to the technical field of organic chemical industry, 2, 4-dichloro-5-fluorobenzoyl chloride is firstly subjected to cyanation to generate 2, 4-dichloro-5-fluorobenzoyl nitrile, then the 2, 4-dichloro-5-fluorobenzoyl nitrile and potassium fluoride are subjected to halogen exchange reaction in the presence of a phase transfer catalyst to generate 2, 4, 5-trifluorobenzoyl nitrile, and the 2, 4, 5-trifluorophenylacetic acid is obtained. The 2, 4, 5-trifluorophenylacetic acid is prepared from 2, 4, 5-trifluorophenylacetic acid and 2, 4, 5-trifluorophenylacetic acid as raw materials, then reduction is performed under p-toluenesulfonhydrazide and sodium borohydride, and hydrolysis is performed under an acidic condition to generate 2, 4, 5-trifluorophenylacetic

The invention relates to the technical field of organic synthesis, in particular to a preparation method for electrochemical synthesis of a 3-trifluoromethyl quinoxalinone compound. The preparation method comprises the following steps: adding a quinoxalinone compound, trifluoromethylsulfonhydrazide and an electrolyte into an electrochemical reaction bottle, and then adding a solvent for dissolving; connecting an anode and a cathode, connecting to a constant-current power supply, then carrying out electrochemical reaction under the reaction current of 8-15mA, and finally separating to obtain the 3-trifluoromethylquinoxalinone compound. Compared with the prior art, the method provided by the invention effectively reduces dependence on harmful oxidants and high-load metal catalysts, and also has the advantages of mild reaction conditions, short process flow, high reaction selectivity and the like.

This invention discloses a sulfonylpyridinone compound, its preparation method, and its applications. The compound is prepared by introducing a sulfonyl group at the 4-position of pyridazin-3(2H)one, giving it multiple functional groups such as sulfone, phenyl, and pyridazinone. The sulfonylpyridinone compound of this invention exhibits a certain antibacterial effect against *Escherichia coli* / *Staphylococcus aureus* and can be used to prepare broad-spectrum antibacterial drugs. Due to its multifunctional nature involving flame retardant groups, this compound is expected to be applied in the flame retardant field. This invention also provides a method for preparing the above-mentioned sulfonylpyridinone compound, achieved through a dehalogenation sulfonation reaction of 4,5-dihalo-2-phenylpyridazin-3(2H)one with sulfonylhydrazine. This reaction process not only avoids transition metal catalysis and the addition of oxidizing or reducing agents, but also features a simple reaction system, a wide range of applicable substrates, and a high yield, which is beneficial for industrial production.

The application relates to a method for preparing 1,2-bis(4-vinylphenyl)ethane and relates to the technical field of organic chemistry, wherein the preparation method comprises the following steps: (1) mixing compound 1, p-toluenesulfonyl hydrazide and organic solvent 1, and then performing reaction to obtain compound 2; (2) reacting the compound 2 in organic solvent 2 under the action of alkali and a polymerization inhibitor to generate 1,2-bis(4-vinylphenyl)ethane. The method has the advantages of mild reaction conditions, simple operation, high product purity, high yield and suitability for industrial production.

The invention relates to the technical field of repairing slurry, in particular to composite material repairing slurry and a preparation process thereof. The invention relates to a composite material repairing slurry, which comprises a filler, a thermal expansion agent, a reinforcing fiber, a thermosetting plastic and a solvent according to a mass ratio of (13-15): (4-5): (10-12): (40-45): (40-45), wherein the filler is a carbon nanotube, the thermal expansion agent is selected from one or more of azodiisobutyronitrile, p-toluenesulfonyl hydrazide, N, N '-dinitroso-N, N'-dimethyl terephthalamide and benzenesulfonyl hydrazide, and the reinforcing fiber is selected from one or more of glass fiber, wollastonite fiber, cellulosic fiber and ceramic fiber. The composite material repairing slurry can be heated to expand after being heated at 100 DEG C, cracks are filled, the repairing difficulty of operators is reduced, and the repaired bumper is good in impact resistance.

This invention relates to an electrochemical synthesis method for fully substituted sulfonated pyrazole compounds. The method includes the following steps: mixing acetylacetone, substituted arylsulfonyl hydrazides, and an electrolyte, adding the mixture to a mixed solvent to obtain a mixed solution; subjecting the mixed solution to an electrochemical reaction to obtain a reaction mixture; and separating and purifying the reaction mixture to obtain the fully substituted sulfonated pyrazole compounds. Compared with existing technologies, this invention uses an electrochemical method to prepare fully substituted sulfonated pyrazole compounds. During the reaction, an iodine-containing electrolyte undergoes an oxidation reaction at the anode to generate iodine free radicals. These iodine free radicals then react with arylsulfonyl hydrazides and acetylacetone with different substituents to form the fully substituted sulfonated pyrazole compounds. This method has advantages such as simple preparation, convenient operation, high atom utilization, and mild reaction conditions.

The present invention belongs to the technical field of organic synthesis, and discloses a toluenesulfonyldiazodiphenylphosphine compound, a preparation method and application thereof. The structural formula of the toluenesulfonyldiazodiphenylphosphine compound is shown in Formula I. The preparation method comprises the following preparation steps: adding p-toluenesulfonylhydrazine to an organic solvent, stirring and dissolving evenly, cooling to 5-10°C, then dripping diphenylphosphine chloride and stirring at room temperature for reaction; after the reaction is completed, heating to 40-50°C, then dripping hydrogen peroxide, heating to reflux temperature for reflux reaction, standing and stratifying after the reaction is completed to remove the aqueous phase layer, taking the organic phase for concentration and crystallization, and obtaining a toluenesulfonyldiazodiphenylphosphine compound. The toluenesulfonyldiazodiphenylphosphine compound of the present invention can be used as a photoinitiator. The synthesis method is simple, the reaction conditions are mild, the raw material sources are wide, the production cost is low, and it is easy to be industrialized and applied.

The invention belongs to the technical field of green organic synthesis, and particularly relates to a preparation method of an N-sulfonyl pyrazole compound. According to the preparation method, the eutectic solvent which is easy to prepare is used as a reaction solvent and also used as a catalyst to catalyze a sulfonyl hydrazine compound and a beta-dicarbonyl compound to be subjected to a cyclization reaction, and the N-sulfonyl pyrazole compound is prepared. According to the preparation method, the product can be obtained only through one-step reaction, preparation is efficient, and operation is easy and convenient; post-treatment is simple, a solid-state product is directly separated out from a system in the reaction process without extraction of an organic solvent, a liquid-state product can be obtained through extraction, and complex post-treatment such as column chromatography purification is not needed; the product is high in yield, good in universality, cheap and easily available in raw materials, low in cost and suitable for industrial large-scale production; meanwhile, the eutectic solvent used in the invention has good biodegradability and small volatility, can be recycled, and meets the development requirements of green chemistry.