53results about How to "React Safe" patented technology

The invention provides a mining inorganic environment-friendly reinforcing material and application thereof, and belongs to the technical field of mining reinforcing materials. A component A comprises the following components in parts by mass: 60-80 parts of anhydrite, 5-20 parts of lime, 5-10 parts of silica fume, 2-8 parts of sodium silicate, 1-0.5 part of a naphthalene water reducer, 3-7 parts of an early strength agent and 0.2-0.8 part of lithium salt; the component B comprises the following components in parts by mass: 50-70 parts of cement clinker, 10-30 parts of slag cement, 5-10 parts of iron powder, 1-8 parts of aluminum sulfate, 5-10 parts of calcium carbonate and 0.5-1 part of sodium tripolyphosphate; the component C is prepared from the following components in parts by mass: 10 to 25 parts of water glass, 10 to 20 parts of emulsion, 40 to 60 parts of water, 5 to 10 parts of high-efficiency water reducing agent and 1 to 5 parts of triethanolamine. The mining inorganic environment-friendly reinforcing material provided by the invention is low in reaction heat and is not easy to cause coal combustion.

The invention discloses a synthesis method of an aryl bidentate phosphine compound, which comprises the following steps of: (1) reacting benzene or alkylbenzene with benzyl chloride or 4-alkyl benzyl chloride at 0-100 DEG C for 0.5-5 hours in the absence of oxygen and under the condition of a lewis acid catalyst to prepare a first intermediate; (2) dropwise adding an alkyl lithium reagent into tetramethylethylenediamine at the temperature of-30 to 40 DEG C under the conditions of no water, no oxygen and a solvent, stirring for 1 to 3 hours, dropwise adding the first intermediate into the mixed solution at normal temperature, and reacting for 4 to 20 hours at the temperature of-20 to 40 DEG C to prepare a second intermediate; and (3) under anhydrous and anaerobic conditions, adding diphenyl phosphine chloride into the second intermediate obtained in the step (2), and reacting at-20 to 80 DEG C for 5-60 hours to obtain the aryl bidentate phosphine compound. The synthesis method disclosed by the invention is simple in process, mild in condition and high in product yield, and has a relatively good industrial prospect.

The invention provides a fluorine-containing polymer wetting reversal agent suitable for shale reservoir protection as well as a preparation method and application of the fluorine-containing polymer wetting reversal agent. The preparation method of the reverse wetting agent comprises the following steps: adding ethylamine, triethylamine and deionized water into a reaction flask, and adding perfluorooctanoyl chloride into the system for reaction; after the reaction is completed, potassium hydroxide and 2-chloroethanol are continuously added for reaction; and after the reaction is completed, obtaining the N-ethyl-N-hydroxyethyl perfluorooctanamide. Adding nanoparticles, a silane coupling agent and ammonia water into the dispersant solution, and carrying out a modification reaction to obtain a modified nanoparticle solution; and adjusting the pH value of the obtained modified nanoparticle solution to 5-9, adding N-ethyl-N-hydroxyethyl perfluorooctanamide, introducing nitrogen to remove oxygen, adding an initiator, and carrying out thermal initiation polymerization reaction to obtain the composite material. The wetting reversal agent disclosed by the invention has excellent wetting reversal performance and a certain filtration reduction effect, and provides innovative thinking for development of a high-performance water-based drilling fluid technology.

The invention relates to the field of high polymer materials, and discloses a visible light repairing type waterborne polyurethane emulsion and a preparation method thereof.The preparation method comprises the following steps that polytetrahydrofuran, isophorone diisocyanate, 2, 2-dimethylolpropionic acid and butyltin dilaurate are taken and placed in a reactor, pre-polymerization chain extension is conducted at the temperature of 60-90 DEG C, and a polyurethane prepolymer is obtained; the preparation method comprises the following steps: firstly, adding ASB-PEG2000-ASB, carrying out chain extension at 40-60 DEG C, then adding butanediol and carbohydrazide, continuously carrying out chain extension, then adding glucose, carrying out crosslinking at 40-60 DEG C, finally cooling to 25-50 DEG C, adding triethylamine, carrying out stirring to form a salt, adding deionized water, carrying out stirring dispersion, and carrying out emulsification so as to prepare the visible light repairing type waterborne polyurethane emulsion. The water-based polyurethane emulsion has the advantages that the water-based polyurethane emulsion has wide absorption in the visible light wave band, the self-repairing efficiency is high, the water-based polyurethane emulsion and polytetrahydrofuran are simultaneously used as soft segments to be introduced into water-based polyurethane, and the prepared water-based polyurethane emulsion has high mechanical performance and a visible light induced self-repairing function.

The invention discloses a device and a process for continuously preparing alpha-phase silicon nitride by a precursor method, and relates to the technical field of preparation of alpha-phase silicon nitride. In the process provided by the invention, the raw material silicon tetrachloride directly reacts with liquid ammonia in the reactor in a vaporific form under the action of high-purity nitrogen through an atomizer, and meanwhile, the by-product ammonium chloride solid generated by the reaction can be ensured to be completely dissolved in the liquid ammonia through the reaction temperature and the reaction pressure and by limiting the feed flow ratio of the raw material silicon tetrachloride to the liquid ammonia; the content of ammonium chloride impurities in generated solid material precursor silicon imine is reduced, and the impurity decomposition amount during subsequent calcination is reduced while the product purity is improved.

The invention belongs to the technical field of noble metal catalysts, and particularly relates to a bifunctional ternary supported noble metal catalyst for preparing 2-hydroxy-gamma-butyrolactone through malic acid hydrogenation and application. The invention relates to a ternary supported noble metal catalyst, which has two catalytic reaction functions of hydrogenation and lactonization, the active metal of the catalyst has a higher catalytic hydrogenation function, and the molecular sieve provides favorable reaction acidic sites for lactonization. A combination of metals Re, Ru and Pt is used as an active metal component of the catalyst; wherein in percentage by weight, the zeolite molecular sieve accounts for 82-84%, and the active metal accounts for 16-18%. According to the present invention, the high activity and high selectivity noble metal catalyst has high activity and high selectivity under neutral and low temperature conditions, and the hydrogenation and the lactonization reaction are simultaneously performed in the synthesis system by using the bifunctional ternary metal catalyst and using the malic acid as the raw material so as to directly obtain the alpha-hydroxy-gamma-butyrolactone;

The invention relates to a method for industrially and continuously producing 2, 2, 4, 4-tetramethyl-1, 3-cyclobutanediol, and belongs to the technical field of organic synthesis. The method for industrially and continuously producing 2, 2, 4, 4-tetramethyl-1, 3-cyclobutanediol comprises the following steps: A, mixing isobutyric acid, a chlorinating agent and a solvent, and carrying out continuous chlorination reaction to obtain isobutyryl chloride; b, mixing the isobutyryl chloride with a dechlorinating agent and a solvent to carry out dehydrochlorination reaction and dimerization reaction to obtain 2, 2, 4, 4-tetramethyl-1, 3-cyclobutanedione; c.2, 2, 2, 4, 4-tetramethyl-1, 3-cyclobutanedione is subjected to continuous hydrogenation reduction, and 2, 2, 4, 4-tetramethyl-1, 3-cyclobutanediol is obtained through preparation of 2, 2, 4, 4-tetramethyl-1, 3-cyclobutanediol; the continuous chlorination reaction in the step A is sequentially controlled to be 30-40 DEG C, stays for 0.5-2 hours, is controlled to be 50-65 DEG C and stays for 0.5-2 hours, and is controlled to be 80-100 DEG C and stays for 1-3 hours. The method provided by the invention realizes industrial large-scale continuous production of 2, 2, 4, 4-tetramethyl-1, 3-cyclobutanediol.

The invention belongs to the technical field of chemical product preparation, and particularly relates to a method for preparing 5-nitrobenzimidazolone through continuous nitration. According to the method, a sulfonic acid group modified Ni-resin material is used as a catalyst, and a tubular reactor-multi-reaction module microchannel reactor combined system is combined, so that continuous preparation of 5-nitrobenzimidazolone can be efficiently realized, a high-purity product can be obtained by adopting the method, meanwhile, the reaction process is safe and stable, and the method is suitable for industrial production. The method has significant value in industrial production.

The present invention relates to a synthetic method of 2-methyl-α-methoxyiminophenylacetic acid methyl ester, and the method flow comprises the following: Step 1: using o-methylphenylacetic acid or o-methylphenylacetamide or o-methylphenylacetic acid methyl ester as raw material, first directly oximating and esterifying with sodium nitrite in sulfuric acid in a solvent; Step 2: "one-pot method" hydrogenation of sodium hydroxide or potassium hydroxide to control pH value, and reacting with dimethyl sulfate to obtain 2-methyl-α-methoxyiminophenylacetic acid methyl ester. The present invention uses o-methylphenylacetic acid or o-methylphenylacetamide or o-methylphenylacetic acid methyl ester as raw material, and adopts safe and reliable sodium nitrite as oximation reagent, avoids using nitrite esters that are flammable and explosive, avoids using expensive methoxyamine hydrochloride, has safe and reliable reaction, low raw material cost, and adopts "one-pot method" in the operation process, has simple and smooth process, mild reaction conditions, and is suitable for industrialized amplification production.

This invention relates to the field of new energy and discloses a highly selective photocatalytic method for producing acetone from methane. The method includes: placing a transparent substrate coated with a photocatalyst in a photocatalytic reactor, adding liquid water, introducing methane gas to purge air, sealing the photocatalytic reactor, and conducting a gas-solid two-phase photocatalytic reaction under light irradiation and heating at 50-100°C to generate a liquid oxygen-containing organic compound, primarily acetone. The photocatalyst is BiVO4, ZnO, or a modified photocatalyst based on morphology control, surface modification, semiconductor composite, or elemental doping of BiVO4 or ZnO. This invention uses methane and water as raw materials, reacting with a photocatalyst in a gas-solid two-phase reaction to produce a liquid oxygen-containing organic compound, primarily acetone, with high acetone yield and selectivity. This invention has advantages such as low requirements for the reaction environment, simple and environmentally friendly process, and low cost.

The application discloses a preparation method of zolmitriptan, relates to the technical field of drug synthesis, and comprises the following steps: adding compound 1 and reagent 1 into solvent 1 to perform a first reaction to obtain compound 2; adding the compound 2, reagent 2 and reagent 3 into solvent 2 to perform a second reaction to obtain compound 3 and the like. Compared with the prior art, the application provides a novel synthetic route for preparing zolmitriptan, the route uses L-4-bromophenylalanine as a starting material, and new synthetic steps are adopted, such as using reagent 5, such as a t-butyl alcohol metal salt and sodium hydride, to construct the oxazolidinone structure in zolmitriptan and using a coupling reaction to construct the indole ring in zolmitriptan, so that the yield of the obtained target product is significantly improved, the use of high-toxicity and high-risk reagents in the existing synthetic route is effectively avoided, and a mild, efficient, green and environmentally-friendly synthetic route for preparing zolmitriptan is provided.

The invention relates to a novel synthesis method of (E)-2-(2-chloromethylphenyl)-2-methoxyiminoacetic acid methyl ester. The method comprises the following steps: Step 1: 2-methyl-α-methoxyiminophenylacetonitrile is used as a raw material and dissolved in a methanol solvent; Step 2: the temperature is controlled at 40-50 DEG C, chlorine is slowly introduced, and the heat preservation reaction time is 5-6 hours; Step 3: methyl is chlorinated, and the hydrogen chloride generated at the same time causes the cyano group to be esterified, so that the key intermediate (E)-2-(2-chloromethylphenyl)-2-methoxyiminoacetic acid methyl ester of trifloxystrobin or kresoxim-methyl is obtained by a "one-pot method", and the temperature is lowered to 0-5 degrees after the heat preservation reaction is completed, and the product is filtered out. The invention uses 2-methyl-α-methoxyiminophenylacetonitrile as a raw material and adopts safe and reliable sodium nitrite as an oximation reagent, avoids the use of inflammable and explosive nitrites, avoids the use of expensive o-hydroxymethylphenylacetic acid lactone, has a safe and reliable reaction, low raw material cost, adopts a "one-pot method", has a simple and smooth process, a short route, and is suitable for industrialized scale-up production.

The invention provides a 1, 4-fullerene C60 derivative and a preparation method thereof. The preparation method of the fullerene C60 derivative comprises the following steps: sequentially adding an organic solvent and a tetrabutyl ammonium hydroxide (TBAOH) solution into a reaction flask, introducing inert gas as shielding gas, adding an ester organic matter and fullerene C60, stirring at 25-60 DEG C, then adding iodine into the system, ending the reaction after a period of time, spin-drying the solvent through a rotary evaporator, and obtaining the fullerene C60 derivative. Carrying out acetonitrile precipitation treatment and filtering to obtain a crude product; and dissolving the crude product in toluene, and separating and purifying by high performance liquid chromatography to obtain the fullerene derivative. The preparation method of the fullerene derivative is simple to operate, mild in reaction condition, safe, easy to control, efficient and high in selectivity. # imgabs0 #

The invention discloses a synthesis method of 3, 3-dimethyl-4, 6, 6-trichloro-7, 7, 7-trifluoroheptanoate, and relates to the technical field of organic synthesis. The 3, 3-dimethyl-4, 6, 6-trichloro-7, 7, 7-trifluoroheptanoate is obtained by taking methyl 3, 3-dimethyl-4, 6, 6-trichloro-7, 7, 7-trifluoroheptanoate and trifluorotrichloroethane as raw materials and carrying out addition reaction under the action of a catalyst. The preparation method comprises the following steps: (1) preparing a catalyst; (2) premixing; (3) initiating reaction; (4) reacting; (5) recycling; (6) layered washing; and (7) dehydrating. The method has the advantages that the reaction is performed in stages, and the catalyst with stable property and flowability is firstly prepared; adding relatively excessive catalyst to initiate reaction at low temperature; and after the reaction is initiated, adding the residual catalyst and the reaction raw materials in a double-dropwise manner. Therefore, the problems of low synthesis efficiency of the catalyst after addition by a one-pot method, high deactivation rate of the catalyst due to too fast temperature rise after initiation of the addition reaction, too long reaction time, low reaction yield and the like are avoided.

The present invention relates to the technical field of nanomaterial preparation, and in particular to hydrophobic silica and its preparation method and application. The method comprises the following steps: vinyl trialkoxy silane and 1,1,1,3,5,5,5-heptamethyl trisiloxane are mixed, a Pt catalyst is added, a microchannel reactor is entered, a heating reaction is carried out, a reactor is entered to continue the stirring reaction, and the reaction heat in the microchannel reactor is used to heat the reactor and remove unreacted components; a hydrophobic agent is obtained by distillation, and the bottom of the reactor is recycled as a catalyst; silica and a hydrophobic agent are mixed, heated and stirred, and low-boiling substances are removed to obtain hydrophobic silica. The present invention uses an alkoxy group and a lipophilic trimethylsiloxy group to prepare a hydrophobic agent, and an effective reaction grafting is carried out with the surface of silica, and the grafting is stable; the microchannel reactor and the reactor can be used together to ensure that the reaction is completely carried out while improving the reaction efficiency. This method not only improves the reaction efficiency, but also achieves the production goal of green energy saving.

The invention belongs to the technical field of multi-scene safety monitoring, and relates to a multi-scene intelligent safety monitoring system. According to the method, the meteorological scene, the load scene and the water scene where the target monitoring object is located currently are determined, potential safety risks can be recognized in advance, basic support is provided for subsequent analysis, and the safety risk of the target monitoring object can be recognized by determining the suitable safety reference values of the health information parameters corresponding to the scene where the target monitoring object is located currently. Whether the structure of the target monitoring object is in an abnormal stress or adverse environment state or not is found in time, a basis is provided for formulating an accurate maintenance plan, and potential safety hazards can be found in time by analyzing the health coefficients of the main beams, the bridge floor and the bridge piers of the scene where the target monitoring object is located currently. And traffic control or maintenance measures are taken, so that accidents are avoided, the target monitoring object can be always kept in a relatively good health state, and the service life of the target monitoring object can be effectively prolonged.

The invention relates to the technical field of chemical engineering, in particular to a preparation method and system of isooctyl nitrate. The invention provides a preparation method of isooctyl nitrate, which comprises the following steps: A) feeding nitric acid, sulfuric acid and isooctyl alcohol into a microchannel reactor according to a flow ratio of 1.05: 2-2.5: 1, and reacting to obtain an isooctyl nitrate crude product; b) performing waste acid regeneration on the waste acid generated by the reaction; and carrying out alkali washing deacidification and water washing desalination on the isooctyl nitrate crude product to obtain the isooctyl nitrate. The preparation method and system provided by the invention are safer in reaction; the micro-channel reactor has no amplification effect from small test to industrial amplification; the catalyst can be used for synthesis reactions under various extreme conditions; the specific surface area is increased, and heat released by reaction is rapidly transferred; and the heat transfer process and the mass transfer process are enhanced. And the conversion rate and the product yield of the prepared isooctyl nitrate are excellent, and the quality of the prepared isooctyl nitrate is excellent.

The invention relates to a method for integrally recycling kettle residues generated in the synthesis process of 5, 5-dimethylhydantoin, which comprises the following steps: 1, dissolving the kettle residues in water, and filtering an adsorbent to obtain a yellow kettle residue solution containing hydantoin; and 2, carrying out vacuum concentration on the kettle residue solution, adding a formaldehyde aqueous solution, and carrying out reaction, filtration and impurity removal to obtain the dimethylol hydantoin product. And 3, adding calcium hydroxide and a catalyst into the kettle residue solution which is obtained by filtering in the step 2 and does not contain hydantoin, and carrying out medium-high temperature reaction, concentration and recrystallization to obtain a glycine product. According to the method, the kettle residues generated in the synthesis process of the 5, 5-dimethylhydantoin are integrally recycled, firstly, the residual 5, 5-dimethylhydantoin product in the kettle residues is used for synthesizing the dihydroxy hydantoin product, then other components in the kettle residues are decomposed into glycine, and all compounds in the kettle residues are effectively utilized. No harmful'three wastes' are generated in the recycling process, so that the treatment cost of the kettle residues is saved, and the environment-friendly integrated recycling of the kettle residues is realized.

The invention relates to the technical field of adiponitrile synthesis, in particular to the field of IPC C07C253, and more particularly relates to a method for synthesizing adiponitrile from butadiene in one step. Comprising the following steps: S1, respectively preheating butadiene, hydrocyanic acid and a catalytic system; s2, preliminarily mixing the preheated butadiene and hydrocyanic acid to form a first mixture; and S3, uniformly mixing the preheated catalytic system to form a second mixture. And S4, carrying out a microchannel reaction on the first mixture and the second mixture to obtain a crude product, and carrying out rectification separation to obtain the product. Through independent heating of the catalyst and the raw material and control of specific parameters, generation of impurities in a non-reactor can be reduced, thereby greatly improving purity and yield.

The present invention relates to a 2,3-hydrogen substituted aminoindole derivative and a preparation method and application thereof, and relates to the field of organic synthesis. The structural formula of the aminoindole derivative is shown in formula (I): wherein R 1 is selected from hydrogen, halogen, alkyl, methoxy, or cyano; R 2 is selected from hydrogen, halogen, alkyl, methoxy, or cyano; R 3 is selected from hydrogen, halogen, alkyl, methoxy, or cyano; R 4 is selected from hydrogen, halogen, alkyl, methoxy, or cyano; R 5 The 2,3-hydrogen substituted aminoindole derivative has biological activity and good modification and derivatization properties.

The invention belongs to the technical field of organic synthesis, and is particularly related to a method for preparing methyl 2-methoxy-4-aminobenzoate, which specifically comprises the following steps: step one: 2-methoxytoluene reacts with chromium oxide to synthesize 2-methoxybenzoic acid; step two: 2-methoxybenzoic acid and methanol prepared in step one are catalyzed by concentrated sulfuric acid to synthesize methyl 2-methoxybenzoate; step three: methyl 2-methoxybenzoate prepared in step two reacts with hydroxylamine sulfate to synthesize methyl 2-methoxy-4-aminobenzoate. The invention has the beneficial effects that the total reaction yield of the method for preparing methyl 2-methoxy-4-aminobenzoate is high, the obtained methyl 2-methoxy-4-aminobenzoate has high purity, is simple to operate, does not require dimethyl sulfate to participate in the reaction, and has mild reaction conditions, thereby reducing production costs, and large-scale production will not affect reaction performance, and the safety and controllability of the production process are higher.

The present invention relates to the technical field of steel slag cooling, and in particular to an explosion-proof system for a steel slag hot stewing container, and more specifically, to an explosion-proof system using a dehydrogenation device in order to effectively prevent explosion accidents caused by the accumulation of hydrogen during the hot stewing cooling process of the steel slag. The dehydrogenation device can effectively remove even low-concentration hydrogen, thereby preventing hydrogen accumulation in advance. The present invention provides an explosion-proof system for a steel slag hot stewing container, that is, an explosion-proof system using a dehydrogenation device in order to prevent hydrogen explosions generated during the hot stewing cooling process of the steel slag, and is characterized in that it includes: a hydrogen collection device for collecting hydrogen in the hot stewing container; a dehydrogenation device with a built-in catalyst for oxidizing hydrogen in a fluid through a catalyst to remove hydrogen; and an energy release device for converting the energy of the oxidation reaction into other energies and releasing them.

The present invention relates to a photochemical synthesis method of a full-peptide nano-colloid. In this method, a double-terminal dityrosine sequence peptide containing aspartic acid D and aminocaproic acid X is used as a cross-linkable precursor, and a mixed solution of a precursor, a photosensitizer, and an oxidant is photochemically synthesized in water. The precursor can be designed from scratch with the help of a peptide database, and standardized solid-phase synthesis can be achieved. The primary structure of the polypeptide chain segment can be transformed into a higher-level structure of a functional colloid within a few minutes by irradiation with a high-intensity photoreactor. The morphology and particle size of the colloid can be regulated by the concentration of the precursor and the pH environment, the degree of cross-linking and the speed of the synthetic reaction can be regulated by the intensity of illumination and the ratio of photosensitizer / oxidant, and the space occupancy, amphiphilicity, water solubility, charge distribution, and encapsulation characteristics of the colloid can be regulated by designing a hydrophilic / hydrophobic / ionic repeating peptide sequence. The nano-colloid is based on a complete peptide unit structure, has excellent biocompatibility, can encapsulate molecules and ions to construct nano-probes, and realizes biomedical applications such as fluorescence imaging and magnetic resonance imaging.

The invention belongs to the technical field of organic synthesis. The invention particularly relates to a preparation method of an edoxaban intermediate. The method comprises the following steps: by taking 2, 5-dimethyl-4, 5, 6, 7-tetrahydrothiazole [5, 4-c] pyridine (compound 1) as a raw material, firstly carrying out oxidation reaction with an oxidizing agent to obtain 5-methyl-4, 5, 6, 7-tetrahydrothiazole [5, 4-c] pyridine-2-formaldehyde (compound 2), then carrying out reaction with chlorite to obtain 5-methyl-4, 5, 6, 7-tetrahydrothiazole [5, 4-c] pyridine-2-formic acid (compound 3), and finally, carrying out reaction on the 5-methyl-4, 5, 6, 7-tetrahydrothiazole [5, 4-c] pyridine-2-formic acid (compound 3) to obtain 5-methyl-4, 5, 6, 7-tetrahydrothiazole [5, 4-c] pyridine-2-formic acid (compound 3). And finally salifying in an organic solution of hydrochloric acid to obtain the edoxaban intermediate (compound 4). The method has the advantages of short reaction route, cheap and easily available materials, mild reaction conditions, high atom economy, high product purity, product quality meeting subsequent requirements, and high yield. # imgabs0 #

The invention belongs to the technical field of organic synthesis, and specifically relates to a method for preparing N2-BOC-isonicotinic acid hydrazine-1-oxygen, comprising the following steps: step 1, synthesizing isoniazid nitrogen oxide: isoniazid methyl ester nitrogen oxide reacts with hydrazine hydrate to obtain a reaction solution of isoniazid nitrogen oxide; step 2, synthesizing N2-BOC-isonicotinic acid hydrazine-1-oxygen: the reaction solution of isoniazid nitrogen oxide in step 1 directly reacts with sodium bicarbonate and BOC anhydride to obtain the final product N2-BOC-isonicotinic acid hydrazine-1-oxygen. Beneficial effects of the invention: the total reaction yield of the preparation method of N2-BOC-isonicotinic acid hydrazine-1-oxygen is high, the obtained N2-BOC-isonicotinic acid hydrazine-1-oxygen is high in purity, and the safety of the raw materials is high, the reaction conditions are mild, the reaction time is short, and the operation is simple.

The invention belongs to the technical field of organic synthesis, and specifically relates to a method for synthesizing trimethylsilyl nitrile, comprising the following steps: (1) synthesizing 1,1,1-trimethylsilylamine: reacting trimethylchlorosilane and ammonia to obtain oily 1,1,1-trimethylsilylamine; (2) synthesizing an intermediate diazonium salt: reacting the 1,1,1-trimethylsilylamine in step (1) with an acid and sodium nitrite; (3) synthesizing trimethylsilyl nitrile: adding a cyaniding agent to the reaction solution in step (2), reacting for 8 to 12 hours, and then extracting and rectifying to obtain the final product trimethylsilyl nitrile. Beneficial effects of the invention: the method for synthesizing trimethylsilyl nitrile uses potassium ferrocyanide or cuprous cyanide as a cyaniding agent, avoids the use of sodium cyanide, potassium cyanide and hydrogen cyanide to endanger the safety of workers, improves the safety of synthesizing trimethylsilyl nitrile, and thus the method for synthesizing trimethylsilyl nitrile is easy to carry out large-scale industrial production.

The invention provides a method and device for preparing 5, 5 '-oxydimethylene-2-furfural, and belongs to the technical field of chemical synthesis. The method for preparing the 5, 5 '-oxydimethylene-2-furfural comprises the following steps: mixing 5-hydroxymethylfurfural, a catalyst and an organic solvent in a micro-mixer to obtain a mixture; the mixture is continuously conveyed into a dynamic tubular reactor to be subjected to a self-etherification reaction, a reaction solution containing 5, 5 '-oxydimethylene-2-furfural is obtained, and the inner diameter of the dynamic tubular reactor is 60-80 mm.

The invention discloses a plasma device and method for treating radioactive waste through liquid metal. A method for treating radioactive waste through liquid metal comprises the following steps that tin is put into a plasma furnace, and the tin is molten into a liquid state under the action of plasma jet to form a liquid metal layer; the radioactive waste resin is dried and crushed into particles, the particles are sent into the liquid metal layer through nitrogen, oxygen is introduced into the liquid metal layer, a glass solution layer is generated on the liquid metal layer, tail gas is decomposed out, and after the glass solution layer is cooled, vitrified solids are obtained. According to the method, volume reduction and innocent treatment of the radioactive waste resin can be simply, conveniently and efficiently achieved, meanwhile, coking is prevented from blocking a furnace body, and the ignition loss rate of bottom slag is reduced.

The invention discloses a continuous preparation method for nitration of sulfentrazone, which comprises the following steps: carrying out nitration reaction on raw materials, namely 1-(2, 4-dichlorophenyl)-3-methyl-4-difluoromethyl-1H-1, 2, 4-triazole-5 (4H) ketone, fuming sulfuric acid and fuming nitric acid to obtain a nitrated substance; the continuous preparation method is safe in reaction process, simple to operate, high in product yield and suitable for industrial production, and efficient mixing of materials can be realized through the continuous reaction device, so that the reaction rate can be remarkably increased, and the prepared sulfentrazone nitration intermediate is high in yield and excellent in quality.

The invention discloses a synthesis method and application of a picoxystrobin intermediate, and the synthesis method of the picoxystrobin intermediate comprises the following steps: adding 200g of acetone, 45-55g of (E)-4-hydroxymethylene-3-isochromone and 15g of sodium hydroxide into a reaction flask, uniformly mixing, then dropwise adding 37-43g of dimethyl sulfate, stirring, reacting, filtering, washing, and drying to obtain the picoxystrobin intermediate. And after the dimethyl sulfate is dropwise added, heating the reaction flask to 20-30 DEG C, carrying out a stirring reaction, filtering the sodium methyl sulfate after the reaction is finished to obtain a filtrate, concentrating the filtrate, adding methanol into the filtrate, crystallizing, filtering and drying. According to the invention, acetone is used as a reaction system, dimethyl sulfate is used for methylation reaction, the reaction period is short, the energy consumption is low, the reaction process is safe, the operation is simple, the production cost is low, and the obtained main by-product and the solvent are almost in an insoluble state and are convenient to separate; the method takes acetone as a solvent, is simple to recover, low in energy consumption, safe to operate, good in environmental protection property and suitable for industrial production.