147results about "Preparation of aldehyde/ketone chelates" patented technology

The invention discloses a curcumin-zinc compound, a preparation method and application of solid dispersions of curcumin-zinc compounds. The weight ratio of the curcumin-zinc compounds to the polyvinylpyrrolidone K30 ranges from 1 to 1 to 1 to 28. The curcumin and the acetic acid are dissolved in the organic solvents and the organic solutions containing the zinc acetate are added drop by drop in the organic solutions containing the curcumin under the protection of the nitrogen; the obtained mixtures are stirred, refluxed, cooled down and filtered; the precipitates are collected and then washed; the precipitates are dried in a vacuum environment so as to obtain the curcumin-zinc compounds. The curcumin-zinc compounds and the PVP-k30 are mixed with each other and dissolved in the ethanol under the protection from the pumped nitrogen; the obtained mixtures are homogeneously filtered and then the filtrates are subject to the spray drying so as to obtain the solid dispersions of the curcumin-zinc compounds. The solid dispersions of the curcumin-zinc compounds overcome various weakpoints of the curcumin, are outstandingly effectively in treatment of various senile diseases, solve the problems widely existing in the treatment of senile diseases that the drug indication is single and the efficacy is not ideal, have simple preparation method and wide application prospect.

An organoruthenium complex represented by the general formula (1-1), bis(acetylacetonato)(1,5-hexadiene)ruthenium and bis(acetylacetonato)(1,3-pentadiene)ruthenium have low melting points, show excellent stability against moisture, air and heat, and are suitable for the film formation by a CVD method. (1-1) wherein X represents a group represented by the general formula (1-2); Y represent a group represented by the general formula (1-2) or a linear or branched alkyl group having 1 to 8 carbon atoms; Z represents a hydrogen atom or an alkyl group having 1 to 4 carbon atoms; and L represents an unsaturated hydrocarbon compound having at least two double bonds: (1-2) wherein Ra and Rb independently represent a linear or branched alkyl group having 1 to 5 carbon atoms.