598results about "Amino preparation from amines" patented technology

This process occurs in the presence of activated carbon or its equivalent by decomposing adsorbed hazardous materials, such as hydrazine and microorganisms, on the carbon surface by radiofrequency energy in the microwave range at near ambient conditions of temperature and pressure. Further microwave oxidation to nonhazardous gases occurs in the presence of a microwaves enhanced oxidation catalyst.

This invention relates to the field of heterogeneous catalysis, and more particularly to catalysts including carbon supports having formed thereon compositions which comprise a transition metal in combination with nitrogen and/or carbon. The invention further relates to the fields of catalytic oxidation and dehydrogenation reactions, including the preparation of secondary amines by the catalytic oxidation of tertiary amines and the preparation of carboxylic acids by the catalytic dehydrogenation of alcohols.

The present invention relates to a method for deuteration of a compound having an aromatic ring, using an activated catalyst, and the method comprises reacting a compound having an aromatic ring with heavy hydrogen source in the presence of an activated catalyst selected from a platinum catalyst, a rhodium catalyst, a ruthenium catalyst, a nickel catalyst and a cobalt catalyst.

Disclosed are: a process for producing purified pentamethylenediamine by simple production steps and in high yield; and others. The process for producing purified pentamethylenediamine comprises: a thermal decomposition step of heating pentamethylenediamine carbonate to yield crude pentamethylenediamine and carbon dioxide; and a distillation step of distilling the crude pentamethylenediamine produced in the thermal decomposition step to yield pentamethylenediamine, wherein the concentration of pentamethylenediamine in the crude pentamethylenediamine is 30 mol% or more relative to the total concentration of pentamethylenediamine and pentamethylenediamine carbonate.

Process for the preparation of substituted dimethyl-(3-aryl-butyl)-amine compounds. The process comprises dehydration by heterogeneous catalysis of substituted 4-dimethylamino-2-aryl-butan-2-ol compounds, to form substituted dimethyl-(3-aryl-but-3-enyl)-amine intermediates, which are then converted by hydrogenation with hydrogen to substituted dimethyl-(3-aryl-butyl)-amine compounds.

Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis, are disclosed.

A novel method for producing amine-aldehyde sulfur scavenging compositions are disclosed, where the method comprises contacting an amine containing component and a aldehyde containing component in the presence of an alcohol at an amine to aldehyde ratio of between about 0.8 and 0.45 for a reaction time and at a reaction temperatures sufficient to produce an amine-aldehyde adduct product having a specific gravity between about 3% and 7% less than the specific gravity of a mixture of starting materials.

The disclosed invention relates to a process, comprising: flowing a first reactant feed stream comprising a reactant substrate and a second reactant feed stream comprising an alkylating agent, an acylating agent or a mixture thereof, in a process microchannel in contact with each other to form a product comprising at least one alkylation product, at least one acylation product, or a mixture thereof; transferring heat from the process microchannel to a heat sink; and removing the product from the process microchannel.

The invention discloses an aggregation-induced emission molecule as well as a preparation method and use thereof. The aggregation-induced emission molecule has a structural formula (shown in the description), wherein when Ar1 and Ar2 are same groups, Ar2 is a group shown in the description; and when Ar2 is hydrogen, Ar1 is a group shown in the description. The preparation method comprises the steps of: starting from a group shown in the description, wherein X=br, and Y=H or X=H, and Y=Br and tetraphenyl ethylene boric acid ester, obtaining derivatives of fluorene containing toluene and triphenylamine units by utilizing an acid-induced intramolecular dehydration reaction, linking tetraphenyl ethylene to a ninth site of the fluorine in a conjugated manner by utilizing a Suzuki reaction, and finally obtaining a target compound. According to the compound disclosed by the invention, the heat stability and the aggregation-induced emission property are good, the solid fluorescence quanta of the compound are high in yield and are emitted by blue lights, and the compound can be applied to a luminescent layer material of a blue-light inorganic light emitting diode; and the reaction conditions of the preparation method are mild, and the yield is high.

The invention relates to novel multi-amino functionalized ionic liquid and a general preparation method thereof, and belongs to the fields of functional materials and preparation. The preparation method comprises the following steps: allowing halogenated aliphatic amine with protective groups to react with organic amine such as imidazole, pyrrole, indole, carbazole, pyrazole, 1,2,4-1-H-triazole, 1-H-tetrazole, purine, piperidine, imidazoline, piperazine, primary aliphatic amine, and secondary aliphatic amine in an aprotic solvent, performing protective group removal of the product to obtain amino functionalized liquid with anions being halogen ions, then performing an anion displacement reaction to displace the halogen anions into other anions; the amino functionalized ionic liquid obtained in the invention is insoluble in non-polar solvents, is simple in separation, and can be used repeatedly; the amino functionalized ionic liquid is applicable to the absorption and separation of acidic gas such as carbon dioxide, sulfur dioxide, hydrogen chloride, hydrogen sulfide, and the like.

The invention discloses a novel diamine compound, and a preparation method and an application thereof. The preparation method of the novel functional diamine compound comprises the following steps: a large conjugate structure comprising benzophenone carbonyl group is obtained; the ketone carbonyl group is subjected to a Wittig or Wittig-Horner reaction, such that a large conjugate system with a triphenylethylene/tetraphenylethylene structure and comprising a halogen atom is obtained; the halogen atom is further subjected to a Suzuki reaction or a plurality steps of reactions, such that a monoamine compound comprising a triphenylethylene/tetraphenylethylene large conjugate system is obtained; the monoamine compound is subjected to a reaction with halogenated nitrobenzene, such that a dinitro monomer comprising triphenylamine and the triphenylethylene/tetraphenylethylene large conjugate system is obtained; and the dinitro monomer is reduced into the novel diamine compound, such that the novel functional diamine compound comprising triphenylamine and a triphenylethylene/tetraphenylethylene structure is obtained. The synthesis method provided by the invention is simple. Purification is easy. The method is suitable for industrial productions. The synthesized diamine compound has a significant aggregation-induced emission property, and can be used for synthesizing high-performance and functional polymers such as polyamide, polyimide, polyamideimide, polyesterimide, and the like.

The invention provides a method for preparing bromhexine hydrochloride, which comprises the steps as follows: (1) 2-amino-3,5-dibromo benzaldehyde and reducing agents are in a reduction reaction to generate 2-amino-3,5-dibromo benzyl alcohol; (2) 2-amino-3, 5-dibromo benzyl alcohol that is obtained in the step (1) reacts with chlorinating agents to generate 2, 4-bromine-6-chloride methylaniline; and (3) 2,4-bromine-6-chloride methylaniline obtained in the step (2) and N-methylcyclohexylamine are in an amination reaction, and then 2, 4-bromine-6-chloride methylaniline and HCl salification agents are in a salification reaction, so that bromhexine hydrochloride is obtained. The preparation method adopts multiple advanced technologies, is easy to get starting materials, and has the advantages of stable property of intermediates, extremely low environment pollution, high yield coefficient of products and high purity.

Provided are immediate or prolonged administration of certain salts of K_ATP channel openers such as diazoxide to a subject to achieve novel pharmacodynamic, pharmacokinetic, therapeutic, physiological, metabolic and compositional outcomes in the treatment of diseases or conditions involving K_ATP channels. Also provided are pharmaceutical formulations, methods of administration and dosing of the salts that achieve these outcomes and reduce the incidence of adverse effects in treated individuals. Further provided are method of co-administering the salts with other drugs to treat diseases of humans and animals.

Compositions and curing agents comprising a benzylated Mannich base composition. The benzylated Mannich base composition includes a reaction product of (a) a substituted phenolic compound having at least one substituent of formula (I):

wherein R₁ is each independently a linear or branched alkyl group having 1 to 4 carbon atoms, and R₂ is hydrogen, methyl, ethyl or phenyl, with (b) a benzylated polyalkylene polyamine (II):

wherein R_A is substituted or unsubstituted benzyl; R_B is each independently R_A, or a hydrogen atom, or a group selected from C₁-C₁₆ linear, cyclic, and branched alkyl, alkenyl, and alkaryl groups; X, Y, and Z are independently selected from C₂-C₁₀ alkylene, and cycloalkylene groups; y is an integer from 0 to 7, and z is an integer from 0 to 4; and, optionally, (c) a multifunctional amine. Amine-epoxy compositions and articles produced from these compositions are also disclosed.

The invention relates to a technique method for preparing quaternary ammonium salt through a reaction of carbonate and ammonium salt without any catalyst; aiming at the shortcoming showed in the former documents (the application number is 200510061094.4) that catalyst is used in the synthesis reaction of the carbonate and the ammonium salt, through improving the technique, the method makes the reaction possible in the condition of no catalyst, which also leads the yield of products of halide quaternary ammonium and sulfuric quaternary ammonium salt to be equal or more than 99 percent so as to avoid the problems such as the impurity of products caused by the difficult separation of catalyst and products and the catalyst which can not be used repeatedly; the technique process of the method is as following, amine is in a neutralization reaction with acid or the solution of acid, when an end point is reached, absolute ammonium salt is obtained after water elimination and drying, then certain amount of carbonate and ammonium salt are separately weighted and put in to a reaction kettle which is then sealed, the carbonate and ammonium salt are in reaction with agitation, the reaction temperature is between 50 to 300 DEG C and the reaction time is between 0.5 to 20 hours.

The invention discloses alkali metal salts of binary or ternary fluorine-containing sulfimide, a method for preparing ionic liquid from the alkali metal salts of binary or ternary fluorine-containing sulfimide, and applications of the alkali metal salts and the ionic liquid as electrolytes in carbon-based supercapacitors, secondary lithium (ion) batteries, and the like. The method for preparing the alkali metal salts of binary or ternary fluorine-containing sulfimide provided by the invention is short in operation steps, and the product is easy to separate and purify, and very high in yield and purity; the binary or ternary fluorine-containing lithium sulfimide provided by the invention is good in thermal stability and hydrolysis resistance; the non-aqueous electrolyte has high conductivity and lithium ion transport number, exhibits good oxidation resistance, and has good compatibility with widely-used electrode materials; meanwhile, the ionic liquid containing binary or ternary fluorine-containing sulfimide anions is characterized by low viscosity and high conductivity, and has a wide electrochemical window.

The invention discloses a preparation method of Boscalid, which comprises the following steps that Suzuki coupling reaction occurs between o-iodoaniline and 4-chlorobenzene boronic acid to produce an intermediate product 4'-chlorinated biphenyl-2-amine under the catalytic effect of Pd/C by using methylbenzene and alkaline water as mixed solvent; and condensation reaction occurs between the 4'-chlorinated biphenyl-2-amine and 2-chloronicotinyl chloride to produce the Boscalid. The preparation method of the Boscalid has the advantages that the production cost is reduced, the yield of the intermediate product 4'-chlorinated biphenyl-2-amine is improved, the total yield of the two steps exceeds 84 percent and the industrial production is expected to be realized.

The invention relates to a method for preparing quaternary amine dual-functional ionic liquid. The quaternary amine dual-functional ionic liquid is prepared by sequentially adopting an anion exchange reaction, a hydrolysis reaction and an acid-alkali neutralizing reaction; a synthetic route is simple; the reaction can be completed at the normal temperature and under the normal pressure with moderate reaction conditions; an apparatus is simple; in the process of preparing the quaternary amine dual-functional ionic liquid by quaternary ammonium hydroxide and acid through the acid-alkali neutralizing reaction, the reaction is sufficient; through ICP-MS and ionic chromatographic detection, the content of sodion and chloridion in the methyl trioctylphosphine ammonium nitric acid ionic liquid prepared by the acid-alkali neutralizing reaction is obviously lower than that of the methyl trioctylphosphine ammonium nitric acid ionic liquid prepared by the anion exchange reaction. In the invention, superficial characteristics on the decomposition temperature, the density, the moisture content of the prepared dual-functional ionic liquid and the intersolubility of normal organic solvents are carried out.

The invention discloses a fluoradene derivative and a preparation method thereof. The preparation method comprises the following steps of: introducing fluoradene rings into compounds, namely carbazole, hexyl carbazole, triphenylamine and hexyl triindole; and catalyzing intramolecular carbon-hydrogen bond activation and hydrogen halide elimination reaction through palladium and efficiently constructing a carbon ring or a heterocyclic compound, particularly constructing the carbon ring with a novel structure. The invention aims to synthesize and characterize a fluoradene structural unit-containing large-tension cyclic compound; and the novel fluoradene structural unit-containing compound is expected to be used in the field of organic photoelectric materials.

The invention discloses a preparation method of long-chain semi-aromatic nylon salt. The method comprises the following steps: firstly, respectively dissolving aromatic dibasic acid and long-chain diamine in an organic solvent under the temperature of 60-80 DEG C, then slowly adding the long-chain diamine into aromatic dibasic acid solution to carry out neutral reaction under the temperature of 60-80 DEG C, adjusting pH value to 7.2-7.4, cooling, separating, washing with the organic solvent, and drying to obtain the long-chain semi-aromatic nylon salt. The long-chain semi-aromatic nylon salt prepared by the invention has higher purity, the speed of the neutral reaction can be controlled, and simultaneously the molar ratio of dibasic acid and diamine can be controlled; the neutral reaction temperature of the organic solvent selected by the invention is lower, the obtained long-chain semi-aromatic nylon salt can be partially dissolved in the organic solvent at the neutral reaction temperature, and is not dissolved in the organic solvent under normal temperature, so as to be convenient to adjust the pH value, separate and purify; and the used organic solvent can be used circularly.

Provided herein are metal halide perovskite nanoplatelets, methods for making metal halide perovskite nanoplatelets, and devices and composite materials that include metal halide nanoperovskite nanoplatelets. The metal halide perovskite nanoplatelets may be stable at ambient temperature and pressure, thereby easing device fabrication.

The invention relates to the field of medicine, and relates to a synthesis and refining method of sulfuric acid terbutaline compound. The structural formula of the compound is as follows: FORMULA; industrially produced hydrochloric acid bambuterol is used as raw material, and then hydrolyzed under alkaline condition to obtain a sulfuric acid terbutaline crude product, the crude product is crystallized in methanol to obtain a refining product with high purity. The reaction condition is mild, the operation is convenient, the total yield is high (about 50%), the environment pollution is less, and the method is suitable for industrial production. The product meets the latest pharmacopoeia criterion in Europe (7.8 version) and the latest pharmacopoeia criterion in the U.S. (36 version).

Provided is an ionic liquid compound with anion containing double Lewis base functional groups. A cation of the ionic liquid compound with the anion containing the double Lewis base functional groups is tetra-alkyl quaternary ammonium, tetra-alkyl quaternary phosphine or N, N-dialkyl-imidazole. The anion is an organic anion which simultaneously contains a carboxylate radical perssad with weak Lewis basicity and a tertiary amine perssad (trialkylamine or tertiary amine on a heterocycle) with the weak Lewis basicity. The ionic liquid compound with the anion containing the double Lewis base functional groups is used for selectively removing hydrogen sulfide (H2S). When partial pressure of the H2S is respectively 10kPa, 20kPa, 50kPa and 100kPa, a molar ratio between an absorptive amount of the H2S and the ionic liquid compound with the anion containing the double Lewis base functional groups is respectively 0.409, 0.484, 0.638 and 0.809. When the partial pressure of the H2S is respectively 10kPa, 20kPa, 50kPa and 100kPa, ideal absorption selectivity of the ionic liquid compound with the anion containing the double Lewis base functional groups to H2S/carbon dioxide (CO2) is respectively 60.3, 39.1, 21.8 and 15.8. The invention discloses a preparation method of the ionic liquid compound with the anion containing the double Lewis base functional groups.

The present invention provides a method for producing amine series with an adamantane framework, including the following steps: step 1: reacting adamantane series in a mixed liquid containing oleum and organic nitrile compounds; step 2: performing hydrolyzing treatment to a reaction liquid obtained in the step 1 to form acidamide series with the adamantane framework; step 3: performing alkali treatment to the acidamide series obtained in the step 2 to form the amine series with the adamantane framework. A method for producing quaternary ammonium salts with the adamantane framework in sequence includes the following steps: step A: reacting the amine series with the adamantane framework dissolved in a dissolvant a with aminic acid and methylene oxide or paraformaldehyde, to form dimethylamine series with the adamantane framework; step B: dissolving the dimethylamine series with the adamantane framework obtained in the step A in a dissolvant b to react with halomethane so as to form quaternary ammonium salt halogenide with the adamantane framework; step C: performing ion exchange to the quaternary ammonium salt halogenide with the adamantane framework to form quaternary ammonium salt hydroxides with the adamantane framework.

An organic electroluminescence device having excellent life characteristics and high reliability and a display apparatus using such a device are provided. In the organic electroluminescence device having organic thin film layers provided between a lower electrode and an upper electrode and including at least a luminescent layer, any one of the organic thin film layers (particularly, the luminescent layer) contains a styrylamine derivative represented by the general formula shown below.

A method for producing a compound having a deuterated aromatic ring or heterocyclic ring according to the invention includes heating a compound having an aromatic ring or heterocyclic ring in the presence of heavy water, a transition metal and a metal which generates deuterium. As the metal which generates deuterium, at least one metal selected from the group consisting of aluminum, magnesium, zinc, iron, lead and tin is preferred. As the transition metal, at least one metal selected from the group consisting of platinum, palladium, ruthenium and rhodium is preferred. The heating is preferably carried out by microwave irradiation.

Fluorene aniline structure-based organic photovoltaic materials are photovoltaic functional materials with different wavelengths of emitted light, which are prepared by the steps of aminating fluorene at the second position by using vinyl aniline to obtain vinyl fluorene aniline, and performing C-C coupling reaction. The novel photovoltaic materials have a basic structure in the specification, wherein Ar is one of groups such as hydrogen, fluorenyl group, anthryl group, pyrenyl group, benzene ring, thiophene and benzothiazole; and R is alkyl group (such as methyl group and octyl group), siloxane group or aryl group (such as phenyl group and thienyl group) with the chain length of C1 to C18.

The invention provides a clean production process of glycine in coproduction with ammonium chloride, which has the capability of co-producing an ammonium chloride product while producing glycine, and also has the capability of co-producing a triethylamine hydrochloride product while producing the glycine. The clean production process comprises the following steps: after a solvent methanol and a catalyst are added into a reactor for a glycine ammonolysis reaction, adding solid ammonium chloroacetate, starting adding triethylamine when the temperature is increased to 65 DEG C, completely adding the triethylamine within one and a half hours, preserving the heat for reacting to two and a half hours until pH value is 7.5; and respectively cooling and carrying out freeze separation to obtain the glycine and the triethylamine hydrochloride. Triethylamine in the triethylamine hydrochloride is recycled by utilizing an ammonium introducing method, and meanwhile, the ammonium chloride product is co-produced.

The invention discloses a continuous producing process of an anti-aging agent 4020, which has the advantages of stability and reliability in operation and high production efficiency. The process comprises the following steps of: adopting 4-aminodiphenylamine, methyl isobutyl ketone and hydrogen as raw materials; mutually preheating all raw materials by a preheater E101; enabling the preheated rawmaterials to enter a reactor; and carrying out catalytic hydrogenation reaction on the raw materials at a high pressure under the effect of a catalyst so as to obtain the anti-aging agent 4020, wherein the reactor is a gas-liquid-solid three-phase fixed bed hydrogenation reactor; the hydrogenation reaction is continuous operation carried out by using the gas-liquid-solid three-phase fixed bed hydrogenation reactor; the gas-liquid-solid three-phase fixed bed hydrogenation reactor comprises a main body container, a discharging opening, a completely discharging opening, a feed pre-distributor, an upper seal head, a lower seal head, an upper support, a lower support and a temperature measuring opening, wherein the feed pre-distributor is an exhaust pipe type pre-distributor which is mounted at the lower part of the main body container; the upper seal head is an elliptical seal head; and the lower seal head is also an elliptical seal head; and the temperature is 165-230 DEG C, the pressureis 5.5-6.0 MPa, the keto-amine ratio is 2-4:1 and the hydrogen-oil ratio is 2000-5000:1 during reaction.

Transparent monolithic aerogels based on silica, the bioderived polymer chitosan, and coordinated ions are employed to serve as a three-dimensional scaffold decorated with metal ions such as Au, Pt and Pd ions. It has also been found that the metal aerogels, such as Au(III) aerogels, can be imaged photolytically to produce nanoparticles.