The invention discloses an <18>F-labeled aggregation-induced emission (AIE) fluorescent / positron emission tomography (PET) dual-mode probe, and a preparation method and application thereof. The compound is denoted as <18>F-TPE-TEG, and has a following structure. The synthesis method of a labelled precursor of the compound comprises the following steps: firstly, adding 2-bromo-1,1,2-triphenylethylene, 4-hydroxyphenylboronic acid and tetrabutylammonium bromide into tetrahydrofuran, and taking K2CO3 and tetrakis(triphenylphosphine)palladium as catalysts to carry out a reaction to obtain 4-hydroxytetraphenylethylene; then dissolving triethylene glycol, triethylamine and p-toluenesulfonyl chloride in dichloromethane, and carrying out a reaction to obtain 8-p-toluenesulfonyloxy-3,6-dioxyoctanol;adding the 4-hydroxytetraphenylethylene, K2CO3, the 8-p-toluenesulfonyloxy-3,6-dioxyoctanol into acetonitrile, and carrying out a reaction to obtain 8-tetraphenylethyleneoxy-3,6-dioxyoctanol; and finally, dissolving the 8-tetraphenylethyleneoxy-3,6-dioxyoctanol, p-toluenesulfonyl chloride and triethylamine in dichloromethane, and carrying out a reaction to obtain the labelled precursor. The <18>F-labeled compound can be used as an AIE fluorescent / PET dual-mode probe to be applied to tumor imaging research.