30 results about "Azine" patented technology

The invention belongs to the technical field of photocatalytic materials, and discloses a triazine-hydrazine bond-based efficient water photolysis COF material as well as a preparation method and application thereof. The material is prepared by carrying out condensation polymerization reaction on benzo [1, 2-b: 3, 4-b ': 5, 6-b'] trithiophene-2, 5, 8-tricarboxaldehyde, 4, 4 ', 4' '-(1, 3, 5-triazine-2, 4, 6-triyl) tribenzaldehyde and hydrazine hydrate. An intramolecular donor-acceptor (D-A) electronic structure is constructed by introducing an electron-rich benzotrithiophene unit and an electron-deficient triazine unit, and the electron-deficient triazine unit and the electron-deficient triazine unit are connected through a full-conjugated azine bond, so that separation and transmission of photo-generated charges are effectively promoted. The preparation method adopts a solvothermal method, and a high-crystallinity product is obtained through acid catalysis and degassing crystallization. The material has high specific surface area and excellent chemical stability, and shows high-efficiency photocatalytic water splitting hydrogen production activity and good cycle stability under the driving of visible light.

The present disclosure provides compounds, in part, compounds having Formula (I) or Formula (II), and their use in the treatment of medical diseases or disorders, such as neurodegenerative diseases, e.g., Parkinson's disease. Pharmaceutical compositions and methods of making the compounds of the present disclosure are provided. These compounds are envisaged to be modulators, e.g., inhibitors, of cyclic ADP ribohydrolase (CD38).

Provided are: a material for organic electroluminescent elements, which is capable of obtaining an organic EL element that is driven at a low voltage, emits light at high efficiency, has long-life characteristics, and is practically useful; and an organic electroluminescent element obtained using the material. A mixed material for an organic electroluminescent element, which contains a compound represented by general formula (1) and a cyclic azine compound represented by general formula (10), and an organic electroluminescent element formed using the mixed material. And m represents the number of repetitions and is 2 or 3. Ar1 is a substituted or unsubstituted aromatic hydrocarbon group having 6-20 carbon atoms or the like, and R2-R7 are each independently hydrogen, a substituted or unsubstituted aromatic hydrocarbon group having 6-20 carbon atoms or the like. Ar2 and Ar3 are each independently a substituted or unsubstituted C6-20 aromatic hydrocarbon group or the like, and L1 is a single bond or a substituted or unsubstituted phenyl group.

This invention relates to the field of electrochemical organic synthesis technology, specifically providing an electrochemically promoted method and application for the synthesis of indole-benzo[selenium]azine ketones. A C3-selenoindole derivative, an organoselenium catalyst, an electrolyte, and an acid are added to an organic solvent to form a reaction system. A graphite felt is used as the anode, and a platinum sheet as the cathode, and a constant current reaction is carried out at room temperature in an air atmosphere. After the reaction is complete, the reactants are post-treated to obtain indole-benzo[selenium]azine ketones. The obtained compounds exhibit significant anti-inflammatory and anti-ulcer dual activities, achieving dual anti-inflammatory and anti-ulcer effects. This solves the problem that traditional NSAIDs only have anti-inflammatory properties but easily cause gastrointestinal damage, and has value for further research and application.

Compounds of formula (I) or pharmaceutically acceptable salts thereof are provided, which are useful for inhibiting Drp1 and treating various Drp11-mediated conditions or diseases. JPEG2026510505000203.jpg3055

A cyclic azine compound of formula (1) is provided. A material for an organic light emitting diode containing the cyclic azine compound of formula (1) is also provided. An organic light emitting diode containing the cyclic azine compound which exhibits both excellent driving voltage characteristics and excellent current efficiency characteristics is also provided.

The present invention relates to a process for providing halogenated 5,6-difluoro-2- methoxybenzenamine and 4,5,6-trifluoro-2-methoxybenzenamine. Further it relates to a process for converting it to substituted azine compounds with herbicidal activity.

This invention discloses a dithiophosphoryl-substituted azine compound and its synthetic method, belonging to the field of organic synthesis technology. The synthetic method uses azine compounds, phosphorus pentasulfide, and alcohols as substrates. In a membrane-free electrolytic cell, using tetrabutylammonium bisulfate as the electrolyte and acetonitrile as the solvent, a three-component dehydrogenation coupling reaction is achieved by constant current electrolysis at room temperature. No metal catalyst or external chemical oxidant is required. Inexpensive phosphorus pentasulfide serves as both the sulfur and phosphorus source. By controlling the electrolysis time, mono- or bis-dithiophosphoryl-substituted azine compounds can be selectively prepared with moderate to excellent product yields. Mechanistic studies show that the reaction proceeds via a free radical-mediated pathway. This method is mild, simple to operate, and has a wide range of applicable substrates, meeting the requirements of green chemistry and providing a new route for the efficient synthesis of functionalized phenoxazine derivatives.

The present invention relates to a solvent system specific to fractionation by liquid-liquid extraction, particularly by centrifugal partition chromatography, of a PVC-based feedstock comprising a PVC polymer and at least one additive. The system comprises two non-miscible liquid phases A and B, each comprising an organic solvent or a mixture of organic solvents selected from the same list consisting of ketones, amides, azines, esters, ethers, halogenated solvents, hydrocarbons, sulfur-containing solvents, and dihydrolevoglucosenone. The partition coefficient of the PVC polymer in the solvent system (ratio of the mass concentrations of the PVC polymer dissolved in phase B and in phase A) tends towards zero, and the partition coefficient of the additive in the solvent system (ratio of the mass concentrations of the additive dissolved in phase B and in phase A) is greater than or equal to 0.05.

The application provides a sulfonic acid solid acid catalyst and a preparation method thereof and a method for catalyzing keto-nitrogen isomerization into 2-pyrazoline, and belongs to the technical field of novel aerospace fuels, so as to solve the technical problems of catalyst separation and recovery difficulty and large acid-containing wastewater discharge in the keto-nitrogen isomerization cyclization method catalyzed by a homogeneous acid. The solid acid catalyst mainly comprises methyl sulfonic acid and a carrier amorphous silica, and the main feature of the solid acid catalyst is a high B acid center. In addition, the application provides a method for synthesizing 2-pyrazoline by catalyzing keto-nitrogen isomerization with a sulfonic acid solid acid catalyst, compared with a traditional homogeneous acid method, the catalyst can be easily separated from the reaction system and can be recycled, so that the production cost is reduced; the generation of a large amount of acid-containing wastewater in the removal process of the acid catalyst is solved, so that the wastewater treatment cost is greatly reduced; the method has high catalytic efficiency, and the catalyst can be recycled for three times, so that the catalytic efficiency is maintained.

The present disclosure relates to an OLED that includes a first electrode; a second electrode facing the first electrode; a first emitting material layer including a first host, a second host and a blue dopant and positioned between the first and second electrodes; a first electron blocking layer including an electron blocking material of a spirofluorene-substituted amine derivative and positioned between the first electrode and the first emitting material layer; and a first hole blocking layer including a first hole blocking material of an azine derivative and positioned between the second electrode and the first emitting material layer, wherein the first host is an anthracene derivative, and the second host is a deuterated anthracene derivative.

The present invention relates to herbicidal compositions comprising at least one compound of formula (I) wherein the variables are defined as given in the specification, and at least one further active compound selected from herbicides of classes b1) to b15) and safeners C.

The present disclosure relates to an organic light emitting device. In particular, the present disclosure relates to an organic light emitting diode and an organic light emitting device each of which includes at least one emitting material layer including a boron-based dopant and an anthracene-based host substituted with at least one deuterium, at least one electron blocking layer including an amine-based compound substituted with at least one fused hetero aryl group, and optionally at least one hole blocking layer including an azine-based or a benzimidazole-based compound. The organic light emitting diode and the organic light emitting device has improved luminous efficiency and enhanced luminous lifespan.

The invention discloses an application of a benzo-aza derivative in preparation of a medicine for preventing or treating atherosclerosis, the benzo-aza derivative is a compound with a chemical structure as shown in a formula I, or a pharmaceutically acceptable salt, a precursor or a metabolite of the compound, and in the formula I, X is halogen or H. The traditional Chinese medicine composition has the technical effects that the plaque stabilizing effect is obvious, the plaque composition is improved, the necrosis core area in the plaque is reduced, the total plaque load can be effectively reduced, the lesion progress is delayed / reversed, the dependence on lipid reduction is avoided, the treatment blank is filled, a brand new plaque stabilizing treatment strategy is provided, and the clinical problem of residual cardiovascular risks is expected to be solved. The safety is good, the organ specificity is high, and the whole body toxicity is low. The invention provides a new treatment normal form, new use of old medicines and large clinical transformation potential, and can be used as a supplement and enhancement of a basic therapy (such as statin lipid reduction) to form a combined treatment scheme of lipid reduction and spot stabilization, thereby realizing multi-channel cooperative control of atherosclerosis.

The present disclosure relates to an organic light emitting device. In particular, the present disclosure relates to an organic light emitting diode and an organic light emitting device each comprising at least one light emitting material layer comprising a boron-based dopant and an anthracene-based host substituted with at least one deuterium, at least one electron blocking layer comprising an amine-based compound substituted with at least one polycyclic aryl group, and optionally at least one hole blocking layer comprising an azine-based or benzimidazole-based compound. The organic light emitting diode and the organic light emitting device have improved luminous efficiency and enhanced luminous lifetime.

The present invention relates to a process for providing substituted azines of formula (T). Further it relates to a process for converting it to substituted azine compounds with herbicidal activity.

The present invention relates to a process for providing halogenated 3,4-difluorophenol and 3,4,5-trifluorophenol. Further it relates to a process for converting it to substituted azine compounds with herbicidal activity.

Provided is a photochromic compound represented by the following General Formula 1. In General Formula 1, Az represents a monovalent azine ring group which is unsubstituted or has a substituent, L represents a divalent or higher linking group, D represents a photochromic dye structure, a and c each independently represent an integer of 1 or more, b represents 0 or an integer of 1 or more; and when there are a plurality of Az's in General Formula 1, the plurality of Az's may be the same as or different from each other, and when there are a plurality of L's in General Formula 1, the plurality of L's may be the same as or different from each other.

The present disclosure provides bifunctional compounds of formula (IA) through the ubiquitin proteasome pathway as selective SMARCA2 degradation agents, and therapeutic uses thereof for the treatment of cancer.

The present invention relates to a process for providing halogenated 3,4-difluoro-2-nitrophenol and 3,4,5-trifluoro-2-nitrophenol. Further it relates to a process for converting it to substituted azine compounds with herbicidal activity.

The present invention relates to a solvent system specifically designed for the liquid-liquid extraction fractionation, particularly by centrifugal partition chromatography, of a PVC-based feed comprising a PVC polymer and at least one additive. The system comprises two immiscible liquid phases, A and B, each containing an organic solvent or a mixture of organic solvents selected from a list consisting of ketones, amides, azines, esters, ethers, halogenated solvents, hydrocarbons, sulfide solvents, and dihydrolevoglucosenone. The partition coefficient of the PVC polymer in the solvent system (ratio of the mass concentrations of PVC polymer dissolved in phase B and in phase A) tends toward zero, and the partition coefficient of the additive in the solvent system (ratio of the mass concentrations of the additive dissolved in phase B and in phase A) is greater than or equal to 0.05.

The invention provides a method for catalytically synthesizing ketazine by using fluorine-containing amide, which comprises the following steps: preheating ketone, fluorine-containing amide, fluorine-containing ammonium acid and a stabilizer EDTA (Ethylene Diamine Tetraacetic Acid) disodium to the reaction temperature of 20-80 DEG C, dropwise adding ammonia water and hydrogen peroxide within 1 hour, and continuously reacting for 0-3 hours to generate ketazine. The method is characterized in that the fluorine-containing amide catalyst is adopted and is different from formamide, acetamide and other amide catalysts, fluorine-containing amide is an amide catalyst difficult to hydrolyze, and the procedure of dehydrating and recycling the catalyst is reduced, so that the energy consumption is greatly reduced, the yield of ketazine is increased, and the yield of ketazine is increased. And the reaction temperature is reduced, so that the generation of an intermediate ketoxime can be reduced.

The application discloses a trace developing xanthene fluorescent dye and a preparation method and application thereof, and belongs to the technical field of criminal investigation. The compound provided by the application has a structural formula as shown in the formula A: wherein R is independently selected from C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C6 cycloalkyl or C2-C5 epoxyalkyl. The trace developing dye compound has the advantages of low cost, small dosage, rapid development, high development quality and simple operation. Compared with similar products, the compound has further improved comprehensive performance and is more convenient to use.

The invention discloses a silane-based azine bond-connected three-dimensional covalent organic framework material, a preparation method thereof and application of the silane-based azine bond-connected three-dimensional covalent organic framework material in hydrogen storage, and belongs to the technical field of hydrogen storage materials and preparation thereof. The problem that the hydrogen storage capacity cannot be further increased due to the fact that the interaction force of an existing COF hydrogen storage material on hydrogen is weak is solved. According to the invention, TFS and hydrazine hydrate are used as monomers to synthesize the silane-based azine bond-connected covalent organic framework material with a three-dimensional space network structure, the three-dimensional structure of the material enables pore channels to be complex and has obvious advantages in gas adsorption, and the azine bond contained in the structure has rich nitrogen atoms, so that the material has a wide application prospect. Hydrogen can be polarized, and the interaction force of hydrogen can be enhanced. Besides, the obtained covalent organic framework material has a highly interspersed structure, the pore size is 0.8 nm, the extremely small pore size is beneficial to enhancing the interaction force between hydrogen and the framework, and the high hydrogen storage capacity is further achieved.

The present invention relates to a process for providing halogenated 3,4-difluoro-2-nitrophenol and 3,4,5-trifluoro-2-nitrophenol. Further it relates to a process for converting it to substituted azine compounds with herbicidal activity.

The utility model provides a device for producing benzophenonetazine in the same kettle, which is characterized in that a reaction kettle adopts a self-suction stirrer, and ammonia gas in a gas phase at the top of the kettle is sucked back to a liquid phase for reuse; the method comprises the following steps: aminating a benzophenone raw material under the condition that water is used as a solvent to form benzophenone imine slurry; an ammonia water outlet is formed in the side surface of the reaction kettle and automatically discharges water after amination is finished; and after dewatering, oxidizing by using high-pressure air under a high-temperature condition to obtain a benzophenone azine solid. The method avoids the use of an organic solvent in a traditional method, the amination reaction and the oxidation reaction are carried out in the same reaction kettle, material transfer is not needed, and all production steps are completed by adopting an automatic means, so that the raw material utilization rate, the labor productivity and the high-quality rate of products are improved.

The present invention relates to a process for providing halogenated 1,2-difluoro-4-methoxy-3- nitrobenzene and 1,2,3-trifluoro-5-methoxy-4-nitrobenzene. Further it relates to a process for converting it to substituted azine compounds with herbicidal activity.