103 results about "Azine" patented technology

The disclosure provides compounds, e.g., compounds of Formula I, and their use in treating medical diseases or disorders, such as cancer. The compounds are contemplated to be modulators of Ras (e.g., K-Ras).

The invention relates to a low-temperature curing polyimide precursor solution and a preparation method thereof. The method comprises the following steps: carrying out condensation polymerization reaction on a dianhydride monomer and a diamine monomer in a reaction solvent to obtain a polyamide acid solution; and adding an amino compound containing one or more special functional groups of pyridine, imidazole, quinoline, pyrimidine and azine into the polyamide acid solution, and fully stirring to enable amino in the compound to fully react with carboxyl in a polyamide acid molecular chain, thereby obtaining the polyimide precursor solution capable of being cured at low temperature. According to the preparation method, the curing temperature of polyimide can be greatly reduced, meanwhile, the mechanical property of the material can be improved, the thermal expansion coefficient can be reduced, and the preparation method can be used for preparing polyimide binders, photoresist, electronic packaging, resin, films, fibers and aerogel.

The present disclosure provides compounds and their methods of use. In particular, the compounds of the present disclosure may be useful for inhibiting RAS proteins, such as KRAS proteins. The disclosed compound may be used in the treatment of cancer and be highly selective for KRAS proteins having the G12D mutation. Alternatively or additionally, said compounds may have broad spectrum activity across a range of KRAS proteins.

The invention provides a positive pole piece, an electrochemical device and an electronic device, the positive pole piece comprises a positive current collector, a positive active material layer and a coating, the coating is located on the surface and / or inside the positive active material layer, and the coating comprises an organic compound, the organic compound includes at least one functional group selected from a cyano group, an isonitrile group, an azinyl group, and an isocyanate group, and the thickness of the coating layer is 0.3 [mu] m to 3 [mu] m. The positive pole piece provided by the invention can improve the thermal safety, the high-temperature cycle performance, the high-temperature storage expansion rate and the mechanical safety of the electrochemical device.

The present invention relates to an organic light emitting device. In particular, the present invention relates to an organic light emitting diode and an organic light emitting device each of which includes at least one emitting material layer comprising an anthracene-based host substituted with at least one deuterium and a boron-based dopant, at least one electron blocking layer comprising an amine-based compound substituted with aryl group, and optionally at least one hole blocking layer comprising at least one of an azine-based compound and a benzimidazole-based compound. The organic light emitting diode and the organic light emitting device has improved luminous efficiency and enhanced luminous lifespan.

The present disclosure relates to an organic light emitting diode that includes at least one emitting material layer including an anthracene-based host and a boron-based dopant, at least one electron blocking layer including an amine-based compound substituted with at least one fused aromatic or hetero aromatic ring, and optionally at least one hole blocking layer including an azine-based compound or a benzimidazole-based compound. The organic light emitting diode has enhanced luminous efficiency as well as excellent luminous lifetime.

To provide: a material for an organic electroluminescent element with which it is possible to obtain an organic EL element that emits light at a high efficiency while being driven at a low voltage, has long life characteristics, and is practically useful; and an organic electroluminescent element obtained by using the same.　This mixed material for an organic electroluminescent element contains a compound represented by general formula (1) and a cyclic azine compound represented by general formula (10). This organic electroluminescent element is formed by using the mixed material. m represents the number of repetitions and is 2 or 3. Ar1 is, inter alia, a substituted or unsubstituted aromatic hydrocarbon group having 6-20 carbon atoms, and R2-R7 are, inter alia, each independently hydrogen or a substituted or unsubstituted aromatic hydrocarbon group having 6-20 carbon atoms. Ar2 and Ar3 are, inter alia, each independently a substituted or unsubstituted aromatic hydrocarbon group having 6-20 carbon atoms, and L1 is a single bond or a substituted or unsubstituted phenyl group.

The present application relates to the technical field of plastic processing aids, and specifically discloses a method for preparing a PVC processing aid. A method for preparing a PVC processing aid, based on elaiophyllic acid, introduces a rigid benzene ring structure through esterification with benzyl alcohol, introduces a ketal and an ester structure through reaction with ethyl levulinate, then reacts with palmitoleic acid to introduce a double bond, and forms an epoxy structure through cyclization with m-chlorobenzene peroxyformic acid, and finally prepares a PVC processing aid, and the prepared PVC processing aid has higher plasticity, lower volatility and lower mobility. In addition, the PVC processing aid of the present application uses biomass renewable resources as raw materials, is non-toxic and harmless, and is environmentally friendly.

A preparation method of the bio-based degradable high-temperature-resistant benzoxazine resin comprises the following steps: firstly, mixing a primary amine compound and an aldehyde compound A, and stirring and reacting for 10-60 minutes at the temperature of 90-120 DEG C to generate a triazine compound; then adding a triazine compound, a bisphenol compound containing a hydroxymethyl diacetal structure synthesized from a bio-based raw material, and an aldehyde compound B into an organic solvent, and carrying out a stirring reaction at 60-90 DEG C for 1-15 h; after the reaction is finished, separating, purifying and drying a reaction product to obtain a benzoxazine monomer; the bisphenol compound containing the hydroxymethyl diacetal structure is selected from xylitol dicondensation p-hydroxy benzaldehyde or xylitol dicondensation m-hydroxy benzaldehyde; and finally, heating and curing the obtained benzoxazine monomer to obtain the benzoxazine resin. The benzoxazine resin prepared by the invention not only has excellent chemical degradability, but also has good high temperature resistance, and the highest glass transition temperature can reach 305 DEG C.

To provide a polyamide composition which is excellent in machine physical properties, heat resistant aging properties at 180°C for a long term of about 2,000 hours, and electric characteristic, is suppressed in bleedout of an additive agent at 80°C and a relative humidity of 95%, makes an additive agent hardly elute in water, and enables obtaining a molded article having excellent external appearance.SOLUTION: A polyamide composition contains: (A) polyamide; 0.1 pt.mass or more and 3 pts.mass or less of (B) branch type polyamine based on 100 pts.mass of the (A) polyamide; 0.05 pt.mass or more and 3 pts.mass or less of (C) steric hindrance phenol; and 0.01 pt.mass or more and 0.5 pt.mass or less of (D) azine dye or phthalocyanine dye. A concentration of (F) halide ion measured by combustion ion chromatography is 500 mass ppm or less based on the total mass of the polyamide composition.SELECTED DRAWING: None

The invention belongs to the technical field of photocatalytic materials, and discloses a triazine-hydrazine bond-based efficient water photolysis COF material as well as a preparation method and application thereof. The material is prepared by carrying out condensation polymerization reaction on benzo [1, 2-b: 3, 4-b ': 5, 6-b'] trithiophene-2, 5, 8-tricarboxaldehyde, 4, 4 ', 4' '-(1, 3, 5-triazine-2, 4, 6-triyl) tribenzaldehyde and hydrazine hydrate. An intramolecular donor-acceptor (D-A) electronic structure is constructed by introducing an electron-rich benzotrithiophene unit and an electron-deficient triazine unit, and the electron-deficient triazine unit and the electron-deficient triazine unit are connected through a full-conjugated azine bond, so that separation and transmission of photo-generated charges are effectively promoted. The preparation method adopts a solvothermal method, and a high-crystallinity product is obtained through acid catalysis and degassing crystallization. The material has high specific surface area and excellent chemical stability, and shows high-efficiency photocatalytic water splitting hydrogen production activity and good cycle stability under the driving of visible light.

The present disclosure provides compounds, in part, compounds having Formula (I) or Formula (II), and their use in the treatment of medical diseases or disorders, such as neurodegenerative diseases, e.g., Parkinson's disease. Pharmaceutical compositions and methods of making the compounds of the present disclosure are provided. These compounds are envisaged to be modulators, e.g., inhibitors, of cyclic ADP ribohydrolase (CD38).

Provided are: a material for organic electroluminescent elements, which is capable of obtaining an organic EL element that is driven at a low voltage, emits light at high efficiency, has long-life characteristics, and is practically useful; and an organic electroluminescent element obtained using the material. A mixed material for an organic electroluminescent element, which contains a compound represented by general formula (1) and a cyclic azine compound represented by general formula (10), and an organic electroluminescent element formed using the mixed material. And m represents the number of repetitions and is 2 or 3. Ar1 is a substituted or unsubstituted aromatic hydrocarbon group having 6-20 carbon atoms or the like, and R2-R7 are each independently hydrogen, a substituted or unsubstituted aromatic hydrocarbon group having 6-20 carbon atoms or the like. Ar2 and Ar3 are each independently a substituted or unsubstituted C6-20 aromatic hydrocarbon group or the like, and L1 is a single bond or a substituted or unsubstituted phenyl group.

A method for selectively controlling weeds in rice, which comprises applying to the crop cultivation area an effective amount of a herbicide A selected from a compound of formula (I) and salts of the compound of formula (I) wherein R1 to R8 are as defined above.

The present invention relates to the technical field of nano-carbon materials, and in particular to a kind of synthetic method of electrochemically active azine alkyne carbon material. Calcium carbide (CaC2) and cyanuric chloride (C3Cl3N3) are uniformly mixed by synthetic method of the present invention, then added into a ball mill and carried out mechanochemical reaction, and the product obtained is washed with 0.1mol / L dilute nitric acid, acetone and deionized water, and then the washed product is freeze-dried to obtain azine alkyne carbon material. The present invention utilizes cyanuric chloride monomer and calcium carbide to synthesize C N heterocyclic azine alkyne carbon material in a controllable structure for the first time through the method for mechanochemical action, while realizing its morphology and structure controllable preparation; During the process, no solvent is needed, operating conditions are mild, chemical effect is remarkable, principle is simple, raw material cost is low and easy to industrial production, the azine alkyne carbon material obtained is made as lithium ion battery negative electrode material, the performances such as charge and discharge capacity, cycle life of composite material can be improved, and it is of great significance for the development of new energy.

The invention provides a synthetic method of methyl ethyl ketazine. According to the synthetic method, a nonionic surfactant is introduced into a traditional hydrogen peroxide method reaction system; the specific reaction system comprises raw materials, a catalyst, an oxidizing agent and an auxiliary agent, wherein the raw materials comprise butanone and ammonia water, the oxidizing agent is hydrogen peroxide, the catalyst is an amide compound, the auxiliary agent is a nonionic surfactant, and preferably, EDTA disodium can be introduced into the hydrogen peroxide. By introducing the auxiliary agent to modulate the reaction system environment, the effective contact area between the reaction materials can be greatly increased, the synthesis reaction is ensured to be more uniform and rapid, the reaction temperature for synthesizing the methyl ethyl ketazine can be reduced, the energy consumption is reduced, and the effects of improving the reaction efficiency and the yield of the methyl ethyl ketazine are also achieved.

This invention relates to the field of electrochemical organic synthesis technology, specifically providing an electrochemically promoted method and application for the synthesis of indole-benzo[selenium]azine ketones. A C3-selenoindole derivative, an organoselenium catalyst, an electrolyte, and an acid are added to an organic solvent to form a reaction system. A graphite felt is used as the anode, and a platinum sheet as the cathode, and a constant current reaction is carried out at room temperature in an air atmosphere. After the reaction is complete, the reactants are post-treated to obtain indole-benzo[selenium]azine ketones. The obtained compounds exhibit significant anti-inflammatory and anti-ulcer dual activities, achieving dual anti-inflammatory and anti-ulcer effects. This solves the problem that traditional NSAIDs only have anti-inflammatory properties but easily cause gastrointestinal damage, and has value for further research and application.

Compounds of formula (I) or pharmaceutically acceptable salts thereof are provided, which are useful for inhibiting Drp1 and treating various Drp11-mediated conditions or diseases. JPEG2026510505000203.jpg3055

The present disclosure relates to an organic light emitting device. In particular, the present disclosure relates to an organic light emitting diode and an organic light emitting device each of which includes at least one emitting material layer comprising an anthracene-based host substituted with at least one deuterium and a boron-based dopant, at least one electron blocking layer comprising an aryl-substituted amine-based compound, and optionally at least one hole blocking layer comprising at least one of an azine-based compound and a benzimidazole-based compound. The organic light emitting diode and the organic light emitting device has improved luminous efficiency and enhanced luminous lifespan.

Provided is a plant or plant part comprising a polynucleotide encoding a mutated cellulose synthase (CESA) polypeptide, wherein the expression of said polynucleotide confers to the plant or plant part tolerance to CESA-inhibiting herbicides, such as azines.

A method for selectively controlling weeds in corn, which comprises applying to the crop cultivation area an effective amount of a herbicidal mixture comprising as a component 1) a herbicide A of the formula (I) wherein R1 to R8 are as defined above and as component 2) at least one further compound selected from compounds B.

The invention relates to the use of at least one organic dialkyl dicarbonate for reducing the content of acetone azine and / or butanone azine in an aqueous polyurethane-polyurea dispersion containing at least one polyurethane-polyurea and acetone azine and / or butanone azine; furthermore to a process for producing an aqueous polyurethane-polyurea dispersion having a reduced content of acetone azine and / or butanone azine; to an aqueous polyurethane-polyurea dispersion containing at least one polyurethane-polyurea and at least one alkyl carbazate; and to an article, cosmetic, coating, adhesive layer, coating formulation, adhesive formulation and / or cosmetic formulation obtainable therefrom.

The present disclosure relates to an OLED that includes a first electrode; a second electrode facing the first electrode; a first emitting material layer including a first host, a second host and a blue dopant and positioned between the first and second electrodes; a first electron blocking layer including an electron blocking material of a spirofluorene-substituted amine derivative and positioned between the first electrode and the first emitting material layer; and a first hole blocking layer including a first hole blocking material of an azine derivative and positioned between the second electrode and the first emitting material layer, wherein the first host is an anthracene derivative, and the second host is a deuterated anthracene derivative.

A cyclic azine compound of formula (1) is provided. A material for an organic light emitting diode containing the cyclic azine compound of formula (1) is also provided. An organic light emitting diode containing the cyclic azine compound which exhibits both excellent driving voltage characteristics and excellent current efficiency characteristics is also provided.

The invention relates to hyperbranched polyamide containing methylpiperazine and polytriphenylamine structures as well as a preparation method and application thereof. The invention relates to a monomer containing methyl piperazine and triphenylamine cores, namely N1, N1-bis (4-aminophenyl)-N4-(4-(bis (4-aminophenyl amino) phenyl) 4-(4-(4-methyl azine-1-yl) benzene) phenyl-1, 4-diamine and hyperbranched polyamide, and a preparation method and application of N1, N1-bis (4-aminophenyl)-N4-(4-(4-methyl azine-1-yl) benzene) phenyl-1, 4-diamine and hyperbranched polyamide. In order to solve the problems of low solubility, poor thermal stability, single color change, low optical contrast and poor electrochemical stability of a triphenylamine-based polyamide material in an organic solvent, a methyl piperazine electron-donating group and multiple electroactive centers are introduced in a molecular design process, and hyperbranched polyamide is synthesized; and the discoloration capability and the cycling stability of the polymer are improved. The solubility of the hyperbranched polyamide is remarkably improved, and the hyperbranched polyamide has excellent electrochromic performance including excellent cycling stability, multiple color changes and high optical contrast. The method is applied to the fields of electrochromic display, sensing, photoelectric detection and the like.

A method for selectively controlling weeds in cereals, which comprises applying to the crop cultivation area an effective amount of a herbicide A selected from a compound of formula (I) and salts of the compound of formula (I) wherein R1 to R8 are as defined above.

A method for selectively controlling weeds in rice, which comprises applying to the crop cultivation area an effective amount of a herbicidal mixture comprising as a component 1) a herbicide A of the formula (I) wherein R1 to R8 are as defined above and as component 2) at least one further compound selected from compounds B.

The present invention relates to a process for providing halogenated 5,6-difluoro-2- methoxybenzenamine and 4,5,6-trifluoro-2-methoxybenzenamine. Further it relates to a process for converting it to substituted azine compounds with herbicidal activity.

The present invention provides novel compounds of formula (I) and pharmaceutical compositions containing these compounds. The compounds of formula (I) can act as PAR-2 inhibitors / antagonists, which renders these compounds highly advantageous for use in therapy, particularly in the treatment or prevention of pain, an autoimmune disorder, an autoinflammatory disorder, an inflammatory disorder, a central nervous system disorder, spinal cord injury, a metabolic disorder, a gastrointestinal disorder, a cardiovascular disorder, a fibrotic disorder, a respiratory disorder, a skin disorder, an allergic disorder, or cancer.