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459 results about "Phenol derivative" patented technology

Phenol derivatives are compounds that are obtained from phenol, a carbolic acid found in household products such as detergents and throat sprays.

Phenol derivative, medicinal composition containing the same, and medicinal use thereof

InactiveUS20070185197A1Lowering excessive intracellular accumulationGood effectBiocideOrganic active ingredientsAcute hyperglycaemiaChemical structure
The present invention provides phenol derivatives represented by the following general formula or pharmaceutically acceptable salts thereof, or prodrugs thereof, which exhibit an inhibitory activity in human SGLT and are useful as agents for the prevention or treatment of a disease associated with hyperglycemia such as diabetes, postprandial hyperglycemia, impaired glucose tolerance, diabetic complications, obesity or the like, and pharmaceutical compositions comprising the same, and pharmaceutical uses thereof. In the chemical structure, R1 and R2 represent H, OH, NH2, etc.; R3and R4represent H, OH, a halogen atom, an optionally substituted alkyl group, etc.; ring A represents an aryl group or a heteroaryl group; G represents a group represented by the following general formula (G); E1 represents H or F; and E2 represents H, F, or a methyl group, etc.
Owner:KISSEI PHARMA

N-diethylaminoacetyl-2,6-dimethylaniline derivatives, preparation method and applications thereof

The invention provides N-diethylaminoacetyl-2,6-dimethylaniline derivatives, a preparation method and applications thereof. The structure of the derivatives is represented by the formula (I). The preparation method comprises the following steps: carrying out reactions between N-diethylaminoacetyl-2,6-dimethylaniline and halogenated compounds to obtain a corresponding quaternary ammonium salt intermediate, and then subjecting the quaternary ammonium salt intermediate to react with corresponding 2-methoxyl-4-subsituted phenol derivative raw material so as to obtain the N-diethylaminoacetyl-2,6-dimethylaniline derivatives. The derivatives can be used as a long-acting local anesthetic drug or a pain relieving drug capable of separating the motion and the feeling, can exert a reversible and lasting local anesthetic effect in organism bodies, do not affect motor function in a certain dosage range, and have an ideal retardant effect on separation of motion and feeling.
Owner:WEST CHINA HOSPITAL SICHUAN UNIV

Alkylphenol modified phenolic amide curing agent and preparation method thereof

The invention discloses an alkylphenol modified phenolic amide curing agent and a preparation method thereof. The alkylphenol modified phenolic amide curing agent comprises the raw components including phenol or phenol derivatives, methanal or paraformaldehyde, polyamine and fatty acid or fatty acid polymer. The preparation method comprises the following steps of: uniformly mixing the fatty acid or the fatty acid polymer and the polyamine, heating the mixture, cooling the mixture, adding the phenol or the phenol derivatives in the mixture, uniformly mixing the methanal or the paraformaldehyde with the mixture, heating the new mixture, and performing dehydration on the new mixture to obtain the product; or the preparation method comprises the following steps of: uniformly mixing the phenol or the phenol derivatives, the polyamine and the methanal or the paraformaldehyde, heating the mixture, adding the fatty acid or the fatty acid polymer into the mixture, heating the new mixture, and performing the dehydration on the new mixture to obtain the product. The curing agent disclosed by the invention is very strong in salt spray corrosion resistance, is superior to polyamide curing agent and curing agent products of modified phenolic aldehyde amide resin and mixtures of the modified phenolic aldehyde amide resin, and has good impact strength and flexibility as well as excellent water tolerance.
Owner:CARDOLITE CHEM ZHUHAI

Topical agent for dermatological use

The objetive of the present invention was to enhance the skin whitening effects and blackening prevention effects and supply safe and stable topical agents for dermatological use. For that purpose 4-Hydroxyphenyl-alpha-D-glucopyranoside was combined with auxiliary agents such as ascorbic acid and its derivatives, crude drugs and its extracts, hydroxycarboxylic acid and its salts, oil soluble glycyrrhiza extract, gentian extract, phenol derivatives and their salts, placenta extract, kojic acid and its derivative, glucosamine and its derivatives, azelaic acid and its derivatives, retinol and its derivatives, pyridoxin and its derivatives, tocopherol and its derivatives, chitosan and its decomposition products, caffeic acid derivatives, hydroxycinnamate and its derivatives, Umbelliferae plant extracts, mycelial cultures and their extracts, plant leaves and their extracts.
Owner:DSM IP ASSETS BV +1

Electrophotographic photoreceptor, image forming apparatus, and process cartridge

An electrophotographic photoreceptor of the present invention comprises a conductive support and a photosensitive layer. The photosensitive layer on the farthest side from the conductive support, includes a phenol derivative-containing layer which contains a phenol derivative having a methylol group and a charge transport material having at least one selected from the group consisting of a hydroxyl group, a carboxyl group, an alkoxysilyl group, an epoxy group, a thiol group and an amino group. An infrared absorption spectrum of the phenol derivative-containing layer satisfies the conditions represented by the following formula (1): (P2 / P1)≦0.2  (1) P1 is an absorbance of a maximum absorption peak in a range of 1560 cm−1 to 1640 cm−1, and P2 is an absorbance of a maximum absorption peak in a range of 1645 cm−1 to 1700 cm−1.
Owner:FUJIFILM BUSINESS INNOVATION CORP

Method for preparing cyclohexanol by catalyzing by base metal catalyst

The invention discloses a method for preparing cyclohexanol by catalyzing phenol hydrogenation by taking a porous carbon material loaded base metal as a catalyst. The synthetic route of the traditional two-step method comprises phenol hydrogenation and cyclohexanol dehydrogenation, and the catalysis of phenol hydrogenation in preparing cyclohexanol is mainly completed through metals, namely nanometer noble metal Pd, Ni radical and the like which have higher activated cracked hydrogen molecules. The method is characterized in that cyclohexanol is prepared in the presence of a solvent by using the porous carbon material loaded base metal as the catalyst, taking phenol or a phenol derivative as a raw material and catalyzing hydrogenation; a general formula of the catalyst is aM@CXy, wherein a indicates the weight percentage content of the metals contained in the catalyst, M indicates the base metal, C indicates carbon, X indicates a doped mixed element, and y indicates the weight percentage content of the mixed element. The method disclosed by the invention can be used for reducing the usage cost of the catalyst by recovering the catalyst by adopting a simple filtering method, and can obtain cyclohexanol by directly concentrating filter liquor obtained through filtration.
Owner:ZHEJIANG UNIV +1

Recovery method of carbon-fiber reinforced epoxy composites

The invention relates to a recovery method of carbon-fiber reinforced epoxy composites. A method in the prior art has defects of strict reaction requirements and high recovery cost. The method provided in the invention comprises the steps of: cutting composites needing to be decomposed into blocks with volumes smaller than 5 cubic centimeters, placing the blocks in a reflux device filled with acid solution, heating for 5-30 minutes at a boiling temperature, drying in vacuum after washing the composites, placing the dried composites in a sealed reactor, adding materials containing hydroxyl and oxidizing agent into the sealed reactor, heating, then cooling the material to normal temperature to obtain primary products, placing and dipping solid products of the primary products in industrial acetone solution after washing the solid products, recycling to obtain carbon fiber, and carrying out liquid separation, extraction and distillation for liquid products to obtain phenol and phenol derivatives. According to the invention, the recovery is carried out under low temperature and low pressure; the reaction condition is mild; the recovery can be controlled easily; the recovery has few by-products, almost no pollution, and no equipment corrosion. The recovery method is a green recovery way.
Owner:NINGBO INST OF MATERIALS TECH & ENG CHINESE ACADEMY OF SCI

Biosynthesis of phloroglucinol and preparation of 1,3-dihydroxybenzene therefrom

ActiveUS7943362B2FungiSugar derivativesPerylene derivativesCoenzyme biosynthesis
The present invention provides methods, enzymes, and cells for the biosynthetic production of phloroglucinol from malonyl-CoA, which is ultimately obtained from simple starting materials such as glucose; also provided are methods for preparing derivatives of biosynthetic phloroglucinol, including, e.g., resorcinol.
Owner:BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIV

Pyrolyzation and debromination method of waste printed circuit board

The invention relates to a pyrolyzation and debromination method of a waste printed circuit board. A nonmetal substance containing the main components of epoxy resin and glass fiber is separated from the waste print circuit board, a nitrogen-contained compound which is cheap and easy to obtain is used as a catalyst, pyrolyzation and debromination are carried out in three temperature stages through controlling a pyrolyzation temperature raising procedure, so that bromine in a nonmetal separator of the waste printed circuit board is volatilized and removed in a low molecular bromide gas product way (HBr, CH3Br), the formation of dioxin as an objectionable constituent is effectively avoided, and meanwhile, a liquid product taking phenol derivatives (phenyl hydroxide, australol) as the main components is obtained, and finally, the effective utilization ratio of the nonmetal material in the waste printed circuit board is improved. The invention has the advantages of simple method, easy obtaining of raw materials, no environment pollution, and the like, and can be widely applied to the recycling of the waste printed circuit board.
Owner:SHAANXI NORMAL UNIV

Targeted ligand-PEG (polyethylene glycol)-cholesterol/tocopherol derivative, and preparation method and application of derivative

The invention belongs to the field of pharmaceutic preparations, and relates to a targeted ligand-PEG (polyethylene glycol)-cholesterol / tocopherol derivative, and a preparation method and an application of the derivative, in particular to an application of the derivative in a composite mechanism mediate tumor targeted drug delivery system. According to the derivative, the preparation method and the application, a drug delivery system consisting of the targeted ligand-PEG-cholesterol / tocopherol derivative with a targeting function, a long circulating function and a pH (power of hydrogen) sensitive function as a functional material, a cation liposome and a drug can simultaneously carry anticancer polypeptide and gene / chemotherapy drugs. According to the system, different drugs are jointly entrapped into the lipid nano drug delivery system and delivered into a targeted cell by utilizing a physicochemical property difference between components or by in-vivo specific targeted recognition, signal conduction blocking and pH triggering PEG chain breaking charge reversion methods, so that a targeted tumor therapeutic effect is improved. According to the derivative, the preparation method and the application, the advantages of the system in directional delivery, co-delivery and the like are proved by in-vivo and in-vitro activity evaluation, the anticancer activity is improved significantly, and definite synergic therapeutic and immunity effects are provided.
Owner:SHENYANG PHARMA UNIVERSITY

Oil-based demulsifying agent and its use in the treatment of drains bored in oil-based mud

An oil-based demulsifying formulation which can be used in the treatment of drains bored in oil-based mud, non ecotoxic and optimally compatible with formation fluids, comprises at least one wetting agent selected from the group consisting of anionic surfactants and at least one demulsifier (or "emulsion breaker") selected from the group consisting of copolymers of ethylene oxide and propylene oxide, alcohol or phenol derivatives with alkoxylated or polyalkoxylated chain formations, polyalkyleneglycols, polyamines, alkoxylated or polyalkoxylated derivatives of amines, quaternary ammonium salts, quaternized alkanolamine esters, alkyl esters of fatty acids or natural oils, possibly alkoxylated or polyalkoxylated, and silicated derivatives such as polysiloxanes.
Owner:INST FR DU PETROLE

Pharmaceutical preparation with cyclosporin A

The invention relates to a pharmaceutical preparation which consists of or contains cyclosporin A, an emulsifying alpha-tocopherol derivative, an ethoxylation product of vegetable oils, fatty acids or fats as a further emulsifier and a pharmaceutically customary alcohol.
Owner:HEXAL AG

Color conversion composition, color conversion film and backlight unit, display and lighting device each comprising same

A color conversion composition converting incident light to light having a longer wavelength than the incident light, and containing the following components (A)-(C): (A) at least one luminescent material; (B) a binder resin; and (C) at least one of tertiary amines, catechol derivatives and nickel compounds, in which the tertiary amines, the catechol derivatives and the nickel compounds have a molar extinction coefficient ε of 100 or less over the whole wavelength range from 400 nm to 800 nm is provided. This color conversion composition achieves a good balance between improvement of color reproducibility and durability if used for a liquid crystal display or an LED lighting device.
Owner:TORAY IND INC

Phosphorus-containing hydroquinone derivatives, process for their production, phosphorus-containing epoxy resins made by using the derivatives, flame-retardant resin compositions, sealing media and laminated sheets

A phosphorus-containing hydroquinone derivative represented by a general formula (1): (where R1 and R2 represent linear or branched alkyl groups that are identical or may be different, and / or R1 and R2 may form a circular group; X represents an oxygen atom or sulfur atom; Y and Z represent hydrogen atom, hydroxy group, linear or branched alkyl group, aralkyl group, alkoxy group, allyl group, aryl group or cyano group, and / or Y and Z may form a circular group). The present invention provides phosphorus-containing hydroquinone derivatives that are useful for intermediate materials for reactive type flame-retardant agents or phosphorus-containing epoxy resins.
Owner:NIPPON CHECMICAL IND CO LTD

O-mercapto phenol derivatives and preparation method thereof

The invention provides o-mercapto phenol derivatives and a preparation method thereof. The preparation method comprises the following steps: a, synthesizing a precursor; b, synthesizing a target product; and c, purifying. Compared with the prior art, the invention provides a brand new synthetic method of poly-substituted o-mercapto phenol for generating a series of novel o-mercapto phenol derivatives. Compared with common o-mercapto phenol derivatives, the o-mercapto phenol derivatives prepared by the method provided by the invention have multiple rings, so that the o-mercapto phenol derivatives are more complex and diverse in structure and further show a broader application prospect in chemical industry production and clinical medicines.
Owner:ANHUI NORMAL UNIV

Anti-microbial/anti-viral composition

An environmentally-safe method for protecting plants is provided for reducing the use of chemically-synthesized pesticide. Specifically, an anti-microbial and / or anti-viral composition comprising a laccase, a cell of a laccase-producing microorganism or a treated product thereof, and one or more kinds of phenol derivatives each represented by the general formula (I) shown below or a salt of the phenol derivative is provided. Furthermore, a plant disease-preventing agent, seed-sterilizing agent, post-harvest agent, and nutrient solution-sterilizing agent, each containing the composition; and plant disease-preventing method, seed-sterilizing method, post-harvest-treatment method, and nutrient solution-sterilizing method in hydroponics and solid-medium hydroponics using each f the agents are provided. (in this formula, each of R1 to R5 independently represents hydrogen, an alkyl group having 1 to 6 carbon atoms, substituted or unsubstituted alkenyl group having 2 to 6 carbon atoms, alkoxy group having 1 to 6 carbon atoms, substituted or unsubstituted aryl group having 6 to 20 core carbon atoms, carboxyl group having 1 to 10 carbon atoms, carbonyl group having 1 to 10 carbon atoms, or halogen atom, and at least one of R1 to R5 is an alkenyl group having 1 to 10 carbon atoms; provided that at least one of R1 and R5 is not an alkoxy group).
Owner:IDEMITSU KOSAN CO LTD

Fluorescent probe for detecting ultra-oxygen anion free radical, synthesis method and use

The invention discloses a new typed fluorescent probe and synthesizing method and application to detect hyperoxygen anion free radical in the cell selectively, which comprises the following steps: dissolving aromatic o-aminophenyl-sulfhydrate or aromatic o-aminophenyl-sulfhydrate derivant with weight rate at 1:2 -3.5 into composite solution with butanol and benzene with bulk rate at 1:0.3-0.6; heating the composite liquid to reflux 3-5h; decompressing to remove solvent; obtaining rough product; recrystallizing through alcohol; drying in the vacuum; obtaining pure product.
Owner:SHANDONG NORMAL UNIV

Benzothiophene compound and application thereof in preventive and/or treatment medicine for breast cancer and osteoporosis

The invention relates to a novel benzothiophene derivative and application thereof in preventive and / or treatment medicine for breast cancer and osteoporosis. The benzothiophene derivative is an ideal selective estrogen receptor modulator, can be used for treating or preventing various indications related to estrogen functions, and is particularly applicable to treating post-menopause breast cancer and osteoporosis. The compound has the advantages that oxidative metabolism is lowered, effective bioavailability is higher, and accordingly, dosage of the compound is little, tolerance of the compound is fine, and side effects are low.
Owner:苏州波锐生物医药科技有限公司

Process for preparing sulfidomethyl phenol derivatives

The invention relates to a method for preparing sulfur methyl phenol derivative which is shown in formula (1). The inventin is characterized in that it takes compound in formula (2) and (3) as catalyst, and proceeds reaction with phenol, formaldehyde and thiols compounds under 50- 250 Deg. C; the carrier in compound of formula (2) is inorganic compound or organic ploymer, R5 is alkyl of direct or branch chain for C1-C8, substituent with benzene ring or alkyl of direct or branch chain containing N, O and / or Si and other atoms; R6 is H or alkyl of direct or branch chain for C1-C8 or alkyl of direct or branch chain containing N, O and / or Si and other atoms or miscellaneous naphthenic base; the carrier in compound of formula (3) is inorganic matter or organic polymer, said R7 and R8 are alkyl of direct or branch chain for C1-C12 respectivly, and R7 and R8 can also be different.
Owner:GUANGZHOU INST OF GEOCHEMISTRY - CHINESE ACAD OF SCI

Diesel fuel and lubricating oil antifoams and methods of use

The present invention relates to diesel fuel and lubrication oil defoaming agents, and crude oil demulsifiers, as well as methods for using same. In particular, the defoaming agents and demulsifiers are comprised of copolymers which have structures constituting a backbone of polysiloxane onto which is grafted an organic group. These structures comprise a polymer of the formula MD.sub.xD'.sub.yD".sub.zM, where M is O.sub.0.5Si(CH.sub.3).sub.3, D is a OSi(CH.sub.3).sub.2, D' is OSi(CH.sub.3)R, D" is OSi(CH.sub.3)R', R is a polyhydric C.sub.6-C.sub.28 organic group, R' is a phenol derivative or a long chain aliphatic group or polyethers, z is between 0 and 80, x+y+z is between 10-200, x / z is .gtoreq.1, and x / (y+z) is between about 1 and about 5, or formula M'D.sub.aM' where M' is O.sub.0.5Si(CH.sub.3).sub.2R, a is between 4-10, and R and D are the same as defined above.
Owner:GRABOWSKI WOJCIECH +1

Resin composition for laser engraving, relief printing plate precursor for laser engraving and method for producing the same, and relief printing plate and method for making the same

A resin composition for laser engraving, including at least a phenol derivative (A) represented by the following Formula (A), a binder polymer (B), and a crosslinking agent (C), wherein the content of the phenol derivative (A) with respect to the total solid content of the resin composition is from 5% by mass to 50% by mass:
Owner:FUJIFILM CORP

Medicine for preventing fish saprolegniasis and application thereof

InactiveCN103142592AGood control effectSmall minimum inhibitory concentrationSalicyclic acid active ingredientsAntimycoticsBiotechnologyCarbamate
The invention relates to medicine for preventing fish saprolegniasis and application thereof. The medicine is combination of one or more types of the following materials: industrial biocide containing bromine, pyridine thioketone salts, 3-iodo-2-propynyl-butyl-carbamate, phenol derivatives, compound containing aldehyde group, mildew preventive 10, 10' oxybis-phenoxarsine, prepared rehmannia roots, garden burnet, pomegranate bark, dyer woad leaves and artemisia carvifolia. The medicine is generally low in a minimal inhibitory concentration to saprolegnia bacterial strains, and is suitable for prevention of the saprolegniasis in aquiculture. The Chinese herbal medicine and composition thereof can prevent the saprolegniasis and have the advantages of being free of pollution and a toxic side effect. The medicine is especially suitable for prevention of the saprolegniasis of aquatic livestock of high economic value, such as ornamental fishes. Food security can be effectively ensured, and quality of aquatic products can be improved.
Owner:SHANGHAI OCEAN UNIV

Catalytic preparation method for hindered phenol derivative antioxygen

The invention discloses a catalytic preparation method for hindered phenol derivative antioxygen. In the invention, a catalytic dehydration process is adopted to prepare the hindered phenol derivative antioxygen, the reaction raw materials are subjected to acidification and monohydrazidation respectively to form two intermediates, and thionyl chloride is not used so as to reduce pollution; and then a solvent and two intermediates are added into a reactor and heated and refluxed to undergo dehydration in the presence of a catalyst, and water is separated out by a water segregator. In the invention, due to the adoption of the catalyst, the reaction temperature is lower, the raw material utilization rate is high, the reaction time is short, and the product yield is high; therefore, the method can contribute to the reduction of production cost and is suitable for industrial production. Evaluation on the use of the antioxygen in polyolefin wire and cables shows that the antioxygen prepared by the method disclosed by the invention has high antioxygen performance and metal passivating capacity.
Owner:CHINA PETROLEUM & CHEM CORP +1

Phosphorus-containing hydroquinone derivative, phosphorus-containing flame-retardant epoxy resin, preparation method and application thereof

The invention discloses a phosphorus-containing hydroquinone derivative, a preparation method and the application thereof as well as phosphorus-containing flame-retardant epoxy resin prepared by the phosphorus-containing hydroquinone derivative, a preparation method and the application thereof. The invention comprises the steps of: first, leading double-aldehyde-group compound and hydroxyl-containing primary amine compound or hydroxyl aldehyde-group compound and phenylenediamine compound to have reaction, and obtaining imine dihydric phenol which has phenolichydroxyl at the two ends of a molecule and contains Schiff base structure on the framework; then, leading the obtained imine dihydric phenol and phosphorous acid diester compound containing active P-H bond to have addition reaction, and obtaining the phosphorus-containing hydroquinone derivative which has phenolichydroxyl at the two ends of the molecule; and finally, leading the obtained phosphorus-containing hydroquinone derivative and epoxy chloropropane to have etherification reaction under the base catalysis, and obtaining the phosphorus-containing flame-retardant epoxy resin which has flame retardance, heat resistance and good comprehensive performance. The experimental result proves that the phosphorus-containing flame-retardant epoxy resin can adapt to the requirement of electronic industry for high-performance high polymer material.
Owner:GUANGZHOU CHEM CO LTD CHINESE ACADEMY OF SCI

Negative resist composition

A negative resist composition comprising: (A) a compound being capable of generating an acid upon irradiation with an actinic ray or a radiation; (B) an alkali-soluble polymer; and (C) at least two crosslinking agents being capable of generating crosslinking with the polymer (B) by an action of an acid, wherein the crosslinking agent (C) comprises at least two compounds having a different skeleton from each other, which are selected from phenol derivatives having at least one of a hydroxymethyl group and an alkoxymethyl group on a benzene ring thereof, in which a sum of the hydroxymethyl group and the alkoxymethyl group is two or more, one of the at least two crosslinking agents comprises one or two benzene rings in the molecule thereof, and other one of the at least two crosslinking agents comprises from 3 to 5 benzene rings in the molecule thereof.
Owner:FUJIFILM CORP +1
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