36 results about "Phthalocyanine dye" patented technology

Provided herein are anti-Programmed Death-Ligand (PD-L1) antibodies, antigen-binding fragments thereof, multispecific antibodies and encoding polynucleotides. Also provided are PD-L1-targeted phthalocyanine dye conjugates, compositions and articles of manufacture containing the conjugates, and methods for their administration to subjects for photoimmunotherapy. In some embodiments, the anti-PD-L1 antibodies, fragments, and conjugates specifically bind to human PD-L1. Among the anti-PD-L1 antibodies are human antibodies and humanized antibodies. Also provided are methods and uses employing the provided anti-PD-L1 antibodies, antigen-binding fragments, and conjugates such for treatment of human patients.

Provided are compositions comprising phthalocyanine (PC)-loaded or naphthalocyanine (NC) dye-loaded nanoparticulate polymeric or lipid micelles and methods for visualization of tumors without optical imaging equipment, the methods comprising injecting a subject with the phthalocyanine (PC)-loaded nanoparticulate amphiphilic polymer or lipid micelles and b) detecting by endoscopy an accumulation of blue dye in a tumor and a demarcation of tumor margins. Also provided are methods for treating a tumor, the method comprising a) administering intravenously to a subject phthalocyanine (PC) dye-loaded or naphthalocyanine (NC) dye-loaded nanoparticulate amphiphilic polymer or lipid micelles; b) detecting by intraoperative photoacoustic imaging an accumulation of dye in a tumor and a demarcation of tumor margins; and / or c) irradiating the PC dye or the NC dye within the tumor with a laser to heat the tumor, thereby decreasing tumor cell viability and / or killing the tumor cells.

Provided are compositions containing a conjugate containing a phthalocyanine dye, including compositions containing stabilizing agents, such as non-ionic surfactants and / or protectants. In some aspects, the compositions result reduced aggregation of the conjugate due to agitation, temperature exposure, and / or pH. Also provided are articles of manufacture containing the compositions containing the conjugates, and methods for their administration to subjects for photoimmunotherapy. In some embodiments, the phthalocyanine dye conjugates are conjugated to a targeting molecule, such as an antibody, that targets the conjugate to a cell or pathogen, such as by binding to a cell surface protein.

Provided are methods for manufacturing a conjugate containing a phthalocyanine dye, including methods that include one or more steps of preparing or producing the conjugate, formulating the conjugate and packaging the conjugate. In some aspects, the manufacturing methods result in the generation of a stable conjugate. Also provided are stable phthalocyanine dye conjugates, compositions and articles of manufacture containing the stable conjugates, and methods for their administration to subjects for photoimmunotherapy. In some embodiments, the phthalocyanine dye conjugates are conjugated to a targeting molecule, such as an antibody, that targets the conjugate to a cell or pathogen, such as by binding to a cell surface protein.

To provide a liquid detergent for hard surfaces which has a proper liquid color in terms of visibility and prevention of staining, while exhibiting superior liquid color stability even under storage in high-temperature conditions.SOLUTION: A liquid detergent for hard surfaces comprises (A) a non-soap anionic surfactant, (B) an aminocarboxylic acid-type chelating agent, (C) a nonionic aromatic compound represented by formula (c1), and (D) a dye selected from phthalocyanine dyes, triphenylmethane dyes, and thiazine dyes, wherein the mass ratio (A+B) / C is 2 to 400. In formula (c1), X represents an oxygen atom or an alkylene group having 1 to 4 carbon atoms, Y each independently represents a chlorine atom or a bromine atom, a, b, and c each independently represent 0 or an integer of 1 to 3, m is 0 or 1, and n is 0 or 1.SELECTED DRAWING: None

The application discloses a kind of high solubility green phthalocyanine dyes for photoresist and a synthesis method thereof, the synthesis method comprises the following steps: (1) S N Ar reaction: under the action of catalyst, attack aromatic ring using carboxyl compound to carry out S N Ar reaction, and after treatment to obtain intermediate P1;(2) preparation of phthalocyanine dye: using intermediate P1 obtained in step (1), metal salt, high-boiling alcohol as raw material, and under the activation condition of catalyst, reaction, after treatment to obtain phthalocyanine P2. The application provides a new type of high solubility phthalocyanine dye molecule, which can be mixed with other colorants to configure green photoresist color paste, which has phthalocyanine as parent structure, improves dye solubility by introducing halogen atom, alkoxycarbonyl, etc., and has excellent thermal stability and light stability;At the same time, the synthesis method provided by the application is simple, easy to mass production, and can be used to improve the quality of LCD display.

Provided are a phthalocyanine dye represented by formula (1) and a method for producing the same. (In the formula, M, L, Q, R2, R3, R7, R8, R4, R5, R6, R9, R10, R11, R12, R13, R14, R15, R16, R17, R18, R19, R20, R21, R22, R23, X2, and X3 are as defined in the claims.)

The invention discloses photo-assisted lithium ion battery positive electrode slurry based on dye sensitization and a preparation method thereof, and relates to lithium ion battery positive electrode slurry and a preparation method thereof. The invention aims to solve the technical problems of large size, complex structure and high cost of the existing photo-rechargeable lithium ion battery. According to the positive electrode paste, N719 dye, N3 dye, black dye or titanyl phthalocyanine dye is added into the positive electrode paste with lithium iron phosphate, nickel-rich layered oxide Li [Ni0. 8Co0. 1Mn0. 1] O2, lithium cobalt oxide or lithium manganate as active substances. The preparation method comprises the following steps: adding the carbon black into a dye solution, then adding the active substance and the polyvinylidene fluoride, and uniformly stirring to obtain positive electrode slurry; after illumination, the capacity of a positive electrode prepared from the slurry is increased from 135.87 mAh g <-1 > to 144.77 mAh g <-1 > to 155.27 mAh g <-1 >, and is increased by 6.55%-14.72%. The invention can be used in the field of lithium ion batteries.

The invention provides a colorful tire sidewall rubber composition, which is prepared from the following components in parts by weight: 10 to 30 parts of natural rubber, 30 to 60 parts of chlorinated isobutylene-isoprene copolymer, 10 to 18 parts of ethylene propylene diene monomer or 35 to 45 parts of butadiene rubber and 1 to 2 parts of stearic acid, 0 to 20 parts of a layered aluminosilicate mineral; 10 to 30 parts of titanium dioxide; 5 to 25 parts of white carbon black; 0.4 to 3 parts of a silane coupling agent; 5-20 parts of an azo dye or a phthalocyanine dye; 4-8 parts of a vulcanizing agent; 1-8 parts of an anti-aging agent; the invention also discloses a preparation method of the sidewall rubber composition. Layered aluminosilicate mineral and azo dye or phthalocyanine dye organic dye are added, hydroxyl on the surface of the layered aluminosilicate mineral adsorbs rubber molecular chains through Van der Waals force, filler agglomeration is reduced, dispersion uniformity is improved, local stress concentration is reduced, and mechanical performance is improved; meanwhile, the color saturation of the colorful tire sidewall composition can be high due to the organic dye, and the colorful tire sidewall composition can be widely applied to preparation of personalized customized colorful tires.

A thermal bubble inkjet printer includes a recording head having a plurality of nozzle rows; the ink at least comprises black ink, cyan ink, magenta ink and yellow ink; the black nozzle row corresponding to the black ink and the yellow nozzle row corresponding to the yellow ink are arranged at a farthest position, and the black nozzle row and the cyan nozzle row corresponding to the cyan ink are arranged at adjacent positions. The black ink contains a self-dispersing pigment, and the cyan ink contains a phthalocyanine dye; the static surface tension gamma K of the black ink and the static surface tension gamma C of the cyan ink meet the condition that gamma K is less than or equal to 38.0 mN / m; gamma K-gamma C < = 4.0 mN / m. According to the thermal bubble type ink-jet printer, even if a heat dissipation plate is not used, heat dissipation of the recording head can be effectively achieved, and printed images are prevented from being disordered. Meanwhile, when the black nozzle row and the cyan nozzle row are adjacently arranged, the black nozzle row can be prevented from being blocked, and the spraying stability and the printing reliability are met.

Disclosed herein are compounds and VLP-compound conjugates comprising a photoactivatable silicon-phthalocyanine dye core and having unique linker groups that facilitate binding the photoactivatable silicon-phthalocyanine dye core VLP-binding moieties. In some aspects, the linker groups can be attached to beta-positions of the compounds and also can be varied in length, which can facilitate improving therapeutic activity of the compounds or VLP-compound conjugates and / or can increase yields associated with methods for making the compounds. Also disclosed are methods of making and using the compounds and VLP-compound conjugates described herein.

The application discloses a blue-green zinc phthalocyanine dye for display photoresist and a synthesis method thereof. The halogen, sulfone group and liposoluble reaction group are introduced into the side chain of the metal phthalocyanine ring through nucleophilic substitution reaction, oxidation reaction and esterification reaction, so that the solubility, heat resistance and coloring power of the dye molecule are further improved. The phthalocyanine dye molecule can be mixed with a yellow pigment to prepare a green photoresist color paste, so as to improve the light transmittance and dispersibility of the color paste, and the color paste has excellent coloring power and heat resistance. Meanwhile, the synthesis method is simple, safe and reliable in operation, and is easy to realize large-scale production.

The invention discloses a special lens for sports scenes. The lens body has a blue-green absorption layer, an auxiliary absorption layer and a green-red absorption layer. The blue-green absorption layer, the auxiliary absorption layer and the green-red absorption layer are pasted together by glue or fixed together by hot-melt pressing process. The blue-green absorption layer is injection-molded by adding 1.2 g of blue light absorber and 1.04 g of phthalocyanine dye per 100 g of substrate material. The auxiliary absorption layer is injection-molded by adding 2.4 g of phthalocyanine dye and 2.4 g of azo nickel metal compound per 100 g of the substrate material. The green-red absorption layer is injection-molded by adding 1.04 g of azo nickel metal compound and 1.2 g of blue light absorber per 100 g of the substrate material. The invention makes the blue and green colors of the object more vivid and improves the contrast and clarity of the color of the object.

The present application relates to a thermal bubble inkjet printer, comprising a recording head having a plurality of nozzle rows; ink, including at least black ink, cyan ink, magenta ink, yellow ink; the black ink corresponding black nozzle row and the yellow ink corresponding yellow nozzle row are arranged at the farthest position, and the black nozzle row and the cyan ink corresponding cyan nozzle row are arranged at the adjacent position; the black ink contains self-dispersible pigment, and the cyan ink contains phthalocyanine dye; the static surface tension γ K of the black ink satisfies γ C of the cyan ink satisfies γ K ≤38.0 mN / m; |γ K -γ C |≤4.0 mN / m. The thermal bubble inkjet printer can effectively realize the heat dissipation of the recording head without using a heat sink, and avoid the disorder of the printed image. At the same time, when the black nozzle row and the cyan nozzle row are arranged adjacent to each other, the black nozzle row can be prevented from being blocked, and the jetting stability and printing reliability can be satisfied.

The application discloses a kind of green display photoresist color paste with dimer phthalocyanine dye and its synthesis method, the synthesis method includes the following steps: (1) coupling reaction: using phthalic dinitrile and binary alcohol, binary acid or binary ester coupling reaction occurs, after treatment, get bridging intermediate B;(2) cyclization reaction, using zinc salt and bridging intermediate B and functional phthalic dinitrile cyclization reaction occurs, after treatment, get dimer phthalocyanine dye compound C.The application provides a new type of dimer phthalocyanine dye molecule, which can be used for the preparation of green display photoresist color paste, and the heat resistance and light resistance are obviously improved compared with monomolecular dye color paste.In addition, the dimer phthalocyanine dye color paste of the application has high transmittance, high contrast, good dispersibility, color strength and other advantages.

Disclosed herein are compounds and biomolecule-compound conjugates comprising a photoactivatable silicon-phthalocyanine dye core and having unique linker groups that facilitate binding the photoactivatable silicon-phthalocyanine dye core biomolecule-binding moieties. In some aspects, the linker groups can be attached to beta-positions of the compounds and also can be varied in length, which can facilitate improving therapeutic activity of the compounds or biomolecule-compound conjugates and / or can increase yields associated with methods for making the compounds. Also disclosed are methods of making and using the compounds and biomolecule-compound conjugates described herein.

The application discloses a kind of high solubility phthalocyanine dyes and its synthesis method and color filter, belong to display technical field.High solubility phthalocyanine dye is selected branched structure is more special, increase its solubility for color photoresist from multiple directions.This kind of dye shows extraordinary solubility in propylene glycol monomethyl ether acetate (PGMEA) It can reach about 15-50wt.%, and suitable for a variety of metal phthalocyanine.In addition, this dye shows excellent spectral properties and thermal stability.Therefore this dye meets the application in color filter, and can further self-regulation color gamut of color filter.

Provided are compositions containing a conjugate containing a phthalocyanine dye, including compositions containing stabilizing agents, such as non-ionic surfactants and / or protectants. In some aspects, the compositions result reduced aggregation of the conjugate due to agitation, temperature exposure, and / or pH. Also provided are articles of manufacture containing the compositions containing the conjugates, and methods for their administration to subjects for photoimmunotherapy. In some embodiments, the phthalocyanine dye conjugates are conjugated to a targeting molecule, such as an antibody, that targets the conjugate to a cell or pathogen, such as by binding to a cell surface protein.

The present application relates to the technical field of functional fiber, in particular to a preparation method of colored fiber with sterilization and aldehyde removal, a composite photocatalyst is formed by using metal phthalocyanine dye, n-butyl titanate and trichloromethyl silane, taking metal phthalocyanine dye as the inner core, taking porous-mesoporous titanium dioxide as the intermediate layer, and taking mesoporous silicon dioxide as the shell layer, the composite photocatalyst is configured into dipping liquid, then the fiber is added and dipped, and the colored fiber is obtained through high-temperature baking, the present application solves the problem of fiber damage caused by the existing photocatalyst, the silicon-oxygen material is used as the wrapping barrier layer, the isolation effect is realized, the light requirement of titanium dioxide and metal phthalocyanine dye is ensured, and the fiber protection and the antibacterial and aldehyde removal performance are considered.

The invention belongs to the technical field of organic synthesis, and discloses a metal phthalocyanine sulfonamide polyoxyethylene ether derivative as well as a preparation method and application thereof. The metal phthalocyanine dye disclosed by the invention has excellent solubility in an organic solvent, can be used for dyeing natural or synthetic resin, wax, paint (such as nitrolacquer or baking varnish) and plastic materials (such as cellulose ether or ester), is particularly suitable for body dyeing of acetyl cellulose, and can also be used for dyeing natural or synthetic polymers or condensation products. A product dyed by the dye has excellent chlorine resistance, industrial smoke resistance and light resistance, is high in color fastness, and can keep good appearance and performance for a long time. The filtering difficulty of an acetyl cellulose acetone spinning solution containing the metal phthalocyanine dye is greatly reduced, the filtering speed is 5-10 times that of a corresponding phthalocyanine dye with a traditional structure, the blockage of a spinning nozzle is effectively reduced, the filtering operation in the acetyl cellulose spinning process is simplified, and the production efficiency is improved.

The invention discloses a medical pressure belt based on nylon spandex elastic flannelette and a preparation method of the medical pressure belt, and relates to the technical field of medical pressure belts. The preparation method comprises the following steps: pretreating brocade spandex elastic flannelette through alkali washing and acid washing, immersing the brocade spandex elastic flannelette into an epsilon-polylysine solution to form a bottom coating, dispersing composite phthalocyanine powder consisting of water-soluble phthalocyanine dye, monosubstituted beta-carboxyl zinc phthalocyanine and iron phthalocyanine derivatives, adjusting the pH value, adding an auxiliary agent to prepare slurry, dip-dyeing a base material with the bottom coating, pre-drying, and curing to obtain a finished product. The pressure belt integrates the functions of efficient antibiosis, deodorization and dyeing, the coating is high in adhesive force, washable and durable, the base material is elastically attached, the biological safety is high, and the pressure belt is suitable for the scenes of clinical infection prevention, postoperative care and the like.

The invention discloses a green phthalocyanine dye for high-solubility photoresist and a synthesis method thereof, the synthesis method comprises the following steps: (1) SNAr reaction: under the action of a catalyst, attacking aromatic rings by using a carboxyl compound to carry out SNAr reaction, and carrying out post-treatment to obtain an intermediate P1; and (2) preparation of phthalocyanine dye: taking the intermediate P1 obtained in the step (1), metal salt and high-boiling-point alcohol as raw materials, carrying out reaction under the activation condition of a catalyst, and carrying out post-treatment to obtain phthalocyanine P2. The invention provides a novel high-solubility phthalocyanine dye molecule, the phthalocyanine dye molecule can be mixed with other coloring agents to prepare green photoresist color paste, phthalocyanine is used as a parent structure, the solubility of the dye is improved by introducing halogen atoms, alkoxycarbonyl and the like, and the phthalocyanine dye molecule has excellent thermal stability and light stability; meanwhile, the synthesis method provided by the invention is simple, is easy for large-scale production, and can be used for improving the display quality of the LCD.

To provide a novel phthalocyanine-based dye with high solubility in a solvent. 【Solution means】A phthalocyanine-based dye composed of compounds of formula (I-A) and formula (I-B). TIFF2026076874000036.tif70141 [M a and M b are different divalent metal atoms; A 1a ~A 8a and A 1b ~A 8b Among them, at least four of each are specific aryloxy groups, and the other substituents are F or Cl.]

To provide an electrostatic charge image developing toner set which produces images whose color shifts over time in a high-temperature, high-humidity environment is prevented.SOLUTION: An electrostatic charge image developing toner is provided, comprising a toner A comprising toner particles A containing an aluminum pigment, a toner B comprising toner particles B containing a phthalocyanine dye, and a toner C comprising toner particles C containing a pyrazolotriazole dye.SELECTED DRAWING: Figure 1

Provided herein are anti-programmed death ligand (PD-L1) antibodies, antigen binding fragments thereof, multispecific antibodies, and encoding polynucleotides. Also provided are PD-L1 targeted phthalocyanine dye conjugates, compositions and articles of manufacture containing the conjugates, and methods of administering the conjugates to an individual for photoimmunotherapy. In some embodiments, the anti-PD-L1 antibodies, fragments, and conjugates specifically bind to human PD-L1. The anti-PD-L1 antibody comprises a human antibody and a humanized antibody. Methods and uses of the provided anti-PD-L1 antibodies, antigen binding fragments, and conjugates for treating human patients are also provided.

Disclosed herein are phthalocyanine dyes, and conjugates thereof, useful as fluorescent reporters for bioassays, for optical imaging and as therapeutic conjugates as the photosensitizing agents in light-based therapies including photoimmuno therapy (PIT). Certain phthalocyanine dyes disclosed herein are water soluble, and possess photophysical and photochemical profiles useful for use in imaging or therapy.

The present invention provides conjugates, compositions and methods for use in photoimmunotherapy, such as photoimmunotherapy induced by activation of a phthalocyanine dye conjugated to a targeting molecule that binds to a protein on a cell, such as an IR700-antibody conjugate. In some embodiments, the phthalocyanine dye conjugate may be activated by irradiation with near-infrared light. Features of the conjugates, compositions, and methods, including doses of the conjugates, provide various benefits, such as lower toxicity and / or better efficacy. In some embodiments, a dual-labeled phthalocyanine dye conjugate is also provided in which the targeting molecule is conjugated to other fluorescent dyes that can be used in photoimmunotherapy and also exhibit better performance, for example, in imaging or detection. Also provided are therapeutic methods of using the conjugates and compositions to treat diseases and conditions, including tumors or cancers.

This application relates to a novel A3B type silicon phthalocyanine containing a new silicon tribenzophthalocyanine dye.

Disclosed herein are compounds and biomolecule-compound conjugates comprising a photoactivatable silicon-phthalocyanine dye core and having unique linker groups that facilitate binding the photoactivatable silicon-phthalocyanine dye core biomolecule-binding moieties. In some aspects, the linker groups can be attached to beta-positions of the compounds and also can be varied in length, which can facilitate improving therapeutic activity of the compounds or biomolecule-compound conjugates and / or can increase yields associated with methods for making the compounds. Also disclosed are methods of making and using the compounds and biomolecule-compound conjugates described herein.